caffeine has been researched along with Fever in 39 studies
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)." | 7.68 | Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993) |
| "Aspirin with caffeine was more effective than aspirin alone after 30 minutes and over the entire study period." | 6.67 | Caffeine as an analgesic adjuvant. A double-blind study comparing aspirin with caffeine to aspirin and placebo in patients with sore throat. ( Baybutt, RI; Fillingim, JM; Lane, AC; Schachtel, BP; Thoden, WR, 1991) |
| "Febrile seizures (FS) is one of the most common convulsive disorders in infants and young children that only occurs during the first years of life in humans, when the cerebellum is still developing." | 5.48 | Cerebellar oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and lactation. ( Crespo, M; León-Navarro, DA; Martín, M, 2018) |
| "Dietitians, exercise physiologists, athletic trainers, and other sports medicine personnel commonly recommend that exercising adults and athletes refrain from caffeine use because it is a diuretic, and it may exacerbate dehydration and hyperthermia." | 4.84 | Caffeine, fluid-electrolyte balance, temperature regulation, and exercise-heat tolerance. ( Armstrong, LE; Casa, DJ; Ganio, MS; Maresh, CM, 2007) |
| " The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)." | 3.68 | Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993) |
| "Aspirin with caffeine was more effective than aspirin alone after 30 minutes and over the entire study period." | 2.67 | Caffeine as an analgesic adjuvant. A double-blind study comparing aspirin with caffeine to aspirin and placebo in patients with sore throat. ( Baybutt, RI; Fillingim, JM; Lane, AC; Schachtel, BP; Thoden, WR, 1991) |
| "Febrile seizures (FS) is one of the most common convulsive disorders in infants and young children that only occurs during the first years of life in humans, when the cerebellum is still developing." | 1.48 | Cerebellar oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and lactation. ( Crespo, M; León-Navarro, DA; Martín, M, 2018) |
| " In conclusion, the study suggests a potentially dangerous effect of concomitant caffeine and mephedrone, and highlights the importance of taking polydrug use into consideration when investigating the acute adverse effect profile of popular recreational drugs." | 1.43 | Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats. ( Fone, KC; Green, AR; King, MV; Shortall, SE, 2016) |
| "When caffeine was administered prior to MDMA, a potentiation of locomotor activity was observed, which consisted in an increase in maximal values and in a prolonged time of activity." | 1.33 | Association of caffeine to MDMA does not increase antinociception but potentiates adverse effects of this recreational drug. ( Camarasa, J; Escubedo, E; Pubill, D, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (38.46) | 18.7374 |
| 1990's | 10 (25.64) | 18.2507 |
| 2000's | 5 (12.82) | 29.6817 |
| 2010's | 9 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crespo, M | 1 |
| León-Navarro, DA | 1 |
| Martín, M | 1 |
| Chagué, F | 1 |
| Georges, M | 1 |
| Gudjoncik, A | 1 |
| Hermerel, T | 1 |
| Garet, G | 1 |
| Israël, J | 1 |
| Hager, JP | 1 |
| Aviat, P | 1 |
| Laurent, Y | 1 |
| Gremeaux, V | 1 |
| Cottin, Y | 1 |
| Zeller, M | 1 |
| Riazi, S | 1 |
| Larach, MG | 1 |
| Hu, C | 1 |
| Wijeysundera, D | 1 |
| Massey, C | 1 |
| Kraeva, N | 1 |
| Zheng, X | 1 |
| Hasegawa, H | 1 |
| Shortall, SE | 1 |
| Green, AR | 1 |
| Fone, KC | 1 |
| King, MV | 1 |
| Nybo, L | 1 |
| Roelands, B | 1 |
| Meeusen, R | 1 |
| Vanattou-Saïfoudine, N | 1 |
| McNamara, R | 2 |
| Harkin, A | 2 |
| Habib, M | 1 |
| Waheed, I | 1 |
| Howden, R | 1 |
| Hanlon, PR | 1 |
| Petranka, JG | 1 |
| Kleeberger, S | 1 |
| Bucher, J | 1 |
| Dunnick, J | 1 |
| Nyska, A | 1 |
| Murphy, E | 1 |
| Kerans, A | 1 |
| O'Neill, B | 1 |
| Camarasa, J | 1 |
| Pubill, D | 1 |
| Escubedo, E | 1 |
| Armstrong, LE | 1 |
| Casa, DJ | 1 |
| Maresh, CM | 1 |
| Ganio, MS | 1 |
| Reimann, HA | 1 |
| Caroff, S | 1 |
| Rosenberg, H | 1 |
| Gerber, JC | 1 |
| Roscioni, C | 1 |
| De Ritis, G | 1 |
| Lotti, A | 1 |
| Pozzessere, C | 1 |
| De Rossi, P | 1 |
| Granato, C | 1 |
| Bruno, VF | 1 |
| Nola, P | 1 |
| Morabito, F | 1 |
| De Tommaso, G | 1 |
| Kokwaro, GO | 1 |
| Szwandt, IS | 1 |
| Glazier, AP | 1 |
| Ward, SA | 1 |
| Edwards, G | 1 |
| Daroca, P | 1 |
| Rodriguez, J | 1 |
| Reaño, M | 1 |
| Canto, G | 1 |
| Miranda, P | 1 |
| Wappler, F | 1 |
| Roewer, N | 1 |
| Köchling, A | 1 |
| Braune, H | 1 |
| Reissinger, T | 1 |
| Schulte am Esch, J | 1 |
| Brooksbank, R | 1 |
| Badenhorst, M | 1 |
| Isaacs, H | 1 |
| Savage, N | 1 |
| Zuev, VP | 2 |
| Minkin, LN | 2 |
| Evglevskaia, IuP | 2 |
| Poe, BS | 1 |
| O'Neill, KL | 1 |
| Maskaleris, T | 1 |
| Lialiaris, T | 1 |
| Triantaphyllidis, C | 1 |
| Du, GG | 1 |
| Oyamada, H | 1 |
| Khanna, VK | 1 |
| MacLennan, DH | 1 |
| Keip, R | 1 |
| Böhme, P | 1 |
| Dascombe, MJ | 2 |
| Dressler, F | 1 |
| Gädeke, R | 1 |
| Planski, B | 1 |
| Schachtel, BP | 1 |
| Fillingim, JM | 1 |
| Lane, AC | 1 |
| Thoden, WR | 1 |
| Baybutt, RI | 1 |
| Hildebrand, SV | 1 |
| Arpin, D | 1 |
| Cardinet, G | 1 |
| Shintani, S | 1 |
| Murase, H | 1 |
| Yamamoto, M | 1 |
| Araki, M | 1 |
| Tsukagoshi, H | 1 |
| Kalow, W | 1 |
| Britt, BA | 2 |
| Terreau, ME | 1 |
| Haist, C | 1 |
| Milton, AS | 1 |
| Glowatzki, G | 1 |
| Strobel, GE | 1 |
| Bianchi, CP | 1 |
| Boyd, EM | 1 |
| Hottenroth, SM | 1 |
4 reviews available for caffeine and Fever
| Article | Year |
|---|---|
Central dopaminergic neurotransmission plays an important role in thermoregulation and performance during endurance exercise.
Topics: Animals; Body Temperature Regulation; Bupropion; Caffeine; Dopamine; Exercise; Female; Fever; Humans | 2016 |
CNS fatigue provoked by prolonged exercise in the heat.
Topics: Caffeine; Central Nervous System; Dopamine; Exercise; Fatigue; Fever; Hot Temperature; Humans; Norep | 2010 |
Alterations in central fatigue by pharmacological manipulations of neurotransmitters in normal and high ambient temperature.
Topics: Animals; Body Temperature; Body Temperature Regulation; Caffeine; Central Nervous System; Central Ne | 2010 |
Caffeine, fluid-electrolyte balance, temperature regulation, and exercise-heat tolerance.
Topics: Adult; Body Temperature Regulation; Caffeine; Dehydration; Exercise; Fever; Humans; Water-Electrolyt | 2007 |
3 trials available for caffeine and Fever
| Article | Year |
|---|---|
[Analgesic, antipyretic and anti-rheumatic activity of 2 preparations evaluated in a multicenter clinical trial].
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Child; Child, Preschool; Clinical Trials | 1982 |
[The experience with solpadeine -- a new analgesic].
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Caffeine; Codeine; Drug Comb | 1997 |
Caffeine as an analgesic adjuvant. A double-blind study comparing aspirin with caffeine to aspirin and placebo in patients with sore throat.
Topics: Adult; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Female; Fever; Humans; | 1991 |
32 other studies available for caffeine and Fever
| Article | Year |
|---|---|
Cerebellar oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and lactation.
Topics: 5'-Nucleotidase; Adenosine; Animals; Caffeine; Cerebellum; Female; Fever; Gait; Lactation; Mothers; | 2018 |
Cardiovascular prevention and at-risk behaviours in a large population of amateur rugby players.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Athletes; Caffeine; Cardiovascular Diseases; Child; Elect | 2019 |
Malignant hyperthermia in Canada: characteristics of index anesthetics in 129 malignant hyperthermia susceptible probands.
Topics: Adolescent; Adult; Aged; Anesthetics; Caffeine; Canada; Child; Child, Preschool; Dantrolene; Female; | 2014 |
Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Caffeine; Discrimination, Psychological; Dopamin | 2016 |
Mechanisms mediating the ability of caffeine to influence MDMA ('Ecstasy')-induced hyperthermia in rats.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adrenergic alpha-Antagonists; | 2010 |
Evaluation of anti-nociceptive, anti-inflammatory and antipyretic activities of Artemisia scoparia hydromethanolic extract.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Artemisia; Caffeine; Carrageenan; Edema | 2013 |
Ephedrine plus caffeine causes age-dependent cardiovascular responses in Fischer 344 rats.
Topics: Age Factors; Animals; Body Temperature; Caffeine; Central Nervous System Stimulants; Drug Synergism; | 2005 |
Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA ("Ecstasy") and MDA ("Love").
Topics: 3,4-Methylenedioxyamphetamine; Animals; Area Under Curve; Behavior, Animal; Body Temperature; Brain | 2006 |
Association of caffeine to MDMA does not increase antinociception but potentiates adverse effects of this recreational drug.
Topics: Analgesics; Animals; Body Temperature; Brain; Caffeine; Central Nervous System Stimulants; Disease M | 2006 |
Caffeinism. A cause of long-continued, low-grade fever.
Topics: Adult; Body Temperature; Caffeine; Coffee; Female; Fever; Humans | 1967 |
Neuroleptic malignant syndrome and malignant hyperthermia.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Caffeine; Fever; Fluphenazine; Halothane; Humans; Musc | 1983 |
Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever.
Topics: Administration, Oral; Animals; Caffeine; Endotoxins; Fever; Injections, Intravenous; Malaria; Male; | 1993 |
Fever from caffeine.
Topics: Caffeine; Cross Reactions; Female; Fever; Humans; Middle Aged; Theophylline | 1996 |
Fulminant malignant hyperthermia associated with ketoacidotic diabetic coma.
Topics: Adult; Caffeine; Cresols; Dantrolene; Diabetic Coma; Diabetic Ketoacidosis; Fever; Halothane; Humans | 1996 |
HSP72 expression in malignant hyperthermia and normal muscle following exposure to caffeine and halothane.
Topics: Animals; Caffeine; Fever; Halothane; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Muscle, Skeleta | 1997 |
[The use of the preparation Solpadeine in dental practice].
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caff | 1997 |
Caffeine modulates heat shock induced apoptosis in the human promyelocytic leukemia cell line HL-60.
Topics: Apoptosis; Caffeine; Dose-Response Relationship, Drug; Fever; Heat-Shock Response; HL-60 Cells; Huma | 1997 |
Induction of cytogenetic damage in human lymphocytes in vitro and of antineoplastic effects in Ehrlich ascites tumor cells in vivo treated by methotrexate, hyperthermia and/or caffeine.
Topics: Adolescent; Adult; Animals; Antineoplastic Agents; Body Weight; Caffeine; Carcinoma, Ehrlich Tumor; | 1998 |
Mutations to Gly2370, Gly2373 or Gly2375 in malignant hyperthermia domain 2 decrease caffeine and cresol sensitivity of the rabbit skeletal-muscle Ca2+-release channel (ryanodine receptor isoform 1).
Topics: Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Caffeine; Ca | 2001 |
[Phenomenology of antipyresis. A study on Fortalidon].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Aspirin; Barbiturates; Caffeine; Codeine; Drug | 1977 |
Effects of methylxanthine drugs on pyrogen-induced hyperthermia.
Topics: Animals; Caffeine; Female; Fever; Male; Pyrogens; Rabbits; Shigella dysenteriae; Theophylline; Time | 1977 |
[The antipyretic effect of Lonarid N in children].
Topics: Acetaminophen; Amobarbital; Caffeine; Child; Child, Preschool; Codeine; Drug Combinations; Drug Eval | 1979 |
[Control of fever using symptomatic measures].
Topics: Adolescent; Adult; Age Factors; Aged; Analgesics; Antitussive Agents; Caffeine; Child; Child, Presch | 1977 |
[Effect of drugs on the pyrogenic reactivity of sheep].
Topics: Alcaligenes; Animals; Atropine; Bromides; Caffeine; Drug Evaluation, Preclinical; Fever; Lipopolysac | 1978 |
Contracture test and histologic and histochemical analyses of muscle biopsy specimens from horses with exertional rhabdomyolysis.
Topics: Anesthesia; Animals; Biopsy, Needle; Caffeine; Contracture; Female; Fever; Halothane; Horse Diseases | 1990 |
[A family study of the caffeine contracture tests on skinned muscle fibers with the propositus affected by exercise-induced hyper-CK-emia].
Topics: Adolescent; Adult; Caffeine; Creatine Kinase; Exercise; Family; Female; Fever; Humans; Male; Middle | 1988 |
Metabolic error of muscle metabolism after recovery from malignant hyperthermia.
Topics: Adolescent; Adult; Anesthesia, General; Caffeine; Calcium; Contracture; Female; Fever; Halothane; Hu | 1970 |
Malignant hyperthermia--an investigation of three patients.
Topics: Adenosine Triphosphatases; Anesthesia, General; Aspartate Aminotransferases; Body Temperature; Caffe | 1971 |
The effect of caffeine on the antipyretic action of aspirin administered during endotoxin induced fever.
Topics: Animals; Aspirin; Caffeine; Endotoxins; Fever; Rabbits | 1972 |
[Thea nigra, a delightful drug].
Topics: Caffeine; China; Drug Therapy; Europe; Fever; History, 16th Century; History, 17th Century; History, | 1967 |
An in-vitro model of anesthetic hypertonic hyperpyrexia, halothane--caffeine-induced muscle contractures: prevention of contracture by procainamide.
Topics: Anesthesia, Inhalation; Animals; Anura; Caffeine; Culture Techniques; Drug Synergism; Fever; Halotha | 1971 |
The toxicity of phenacetin at the range of the oral LD50(100 days) in albino rats.
Topics: Animals; Asthenia; Ataxia; Caffeine; Chemical and Drug Induced Liver Injury; Cyanosis; Dehydration; | 1968 |