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caffeine and Fever

caffeine has been researched along with Fever in 39 studies

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
" The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)."7.68Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993)
"Aspirin with caffeine was more effective than aspirin alone after 30 minutes and over the entire study period."6.67Caffeine as an analgesic adjuvant. A double-blind study comparing aspirin with caffeine to aspirin and placebo in patients with sore throat. ( Baybutt, RI; Fillingim, JM; Lane, AC; Schachtel, BP; Thoden, WR, 1991)
"Febrile seizures (FS) is one of the most common convulsive disorders in infants and young children that only occurs during the first years of life in humans, when the cerebellum is still developing."5.48Cerebellar oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and lactation. ( Crespo, M; León-Navarro, DA; Martín, M, 2018)
"Dietitians, exercise physiologists, athletic trainers, and other sports medicine personnel commonly recommend that exercising adults and athletes refrain from caffeine use because it is a diuretic, and it may exacerbate dehydration and hyperthermia."4.84Caffeine, fluid-electrolyte balance, temperature regulation, and exercise-heat tolerance. ( Armstrong, LE; Casa, DJ; Ganio, MS; Maresh, CM, 2007)
" The effects of malaria infection due to Plasmodium berghei and Escherichia coli endotoxin-induced fever on the metabolism of orally-administered caffeine (CA: 10 mg/kg) to its primary metabolites (theobromine (TB), paraxanthine (PX) and theophylline (TH)) were studied in 5-week-old male Wistar rats (n = 5 for each treatment)."3.68Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever. ( Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA, 1993)
"Aspirin with caffeine was more effective than aspirin alone after 30 minutes and over the entire study period."2.67Caffeine as an analgesic adjuvant. A double-blind study comparing aspirin with caffeine to aspirin and placebo in patients with sore throat. ( Baybutt, RI; Fillingim, JM; Lane, AC; Schachtel, BP; Thoden, WR, 1991)
"Febrile seizures (FS) is one of the most common convulsive disorders in infants and young children that only occurs during the first years of life in humans, when the cerebellum is still developing."1.48Cerebellar oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and lactation. ( Crespo, M; León-Navarro, DA; Martín, M, 2018)
" In conclusion, the study suggests a potentially dangerous effect of concomitant caffeine and mephedrone, and highlights the importance of taking polydrug use into consideration when investigating the acute adverse effect profile of popular recreational drugs."1.43Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats. ( Fone, KC; Green, AR; King, MV; Shortall, SE, 2016)
"When caffeine was administered prior to MDMA, a potentiation of locomotor activity was observed, which consisted in an increase in maximal values and in a prolonged time of activity."1.33Association of caffeine to MDMA does not increase antinociception but potentiates adverse effects of this recreational drug. ( Camarasa, J; Escubedo, E; Pubill, D, 2006)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199015 (38.46)18.7374
1990's10 (25.64)18.2507
2000's5 (12.82)29.6817
2010's9 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crespo, M1
León-Navarro, DA1
Martín, M1
Chagué, F1
Georges, M1
Gudjoncik, A1
Hermerel, T1
Garet, G1
Israël, J1
Hager, JP1
Aviat, P1
Laurent, Y1
Gremeaux, V1
Cottin, Y1
Zeller, M1
Riazi, S1
Larach, MG1
Hu, C1
Wijeysundera, D1
Massey, C1
Kraeva, N1
Zheng, X1
Hasegawa, H1
Shortall, SE1
Green, AR1
Fone, KC1
King, MV1
Nybo, L1
Roelands, B1
Meeusen, R1
Vanattou-Saïfoudine, N1
McNamara, R2
Harkin, A2
Habib, M1
Waheed, I1
Howden, R1
Hanlon, PR1
Petranka, JG1
Kleeberger, S1
Bucher, J1
Dunnick, J1
Nyska, A1
Murphy, E1
Kerans, A1
O'Neill, B1
Camarasa, J1
Pubill, D1
Escubedo, E1
Armstrong, LE1
Casa, DJ1
Maresh, CM1
Ganio, MS1
Reimann, HA1
Caroff, S1
Rosenberg, H1
Gerber, JC1
Roscioni, C1
De Ritis, G1
Lotti, A1
Pozzessere, C1
De Rossi, P1
Granato, C1
Bruno, VF1
Nola, P1
Morabito, F1
De Tommaso, G1
Kokwaro, GO1
Szwandt, IS1
Glazier, AP1
Ward, SA1
Edwards, G1
Daroca, P1
Rodriguez, J1
Reaño, M1
Canto, G1
Miranda, P1
Wappler, F1
Roewer, N1
Köchling, A1
Braune, H1
Reissinger, T1
Schulte am Esch, J1
Brooksbank, R1
Badenhorst, M1
Isaacs, H1
Savage, N1
Zuev, VP2
Minkin, LN2
Evglevskaia, IuP2
Poe, BS1
O'Neill, KL1
Maskaleris, T1
Lialiaris, T1
Triantaphyllidis, C1
Du, GG1
Oyamada, H1
Khanna, VK1
MacLennan, DH1
Keip, R1
Böhme, P1
Dascombe, MJ2
Dressler, F1
Gädeke, R1
Planski, B1
Schachtel, BP1
Fillingim, JM1
Lane, AC1
Thoden, WR1
Baybutt, RI1
Hildebrand, SV1
Arpin, D1
Cardinet, G1
Shintani, S1
Murase, H1
Yamamoto, M1
Araki, M1
Tsukagoshi, H1
Kalow, W1
Britt, BA2
Terreau, ME1
Haist, C1
Milton, AS1
Glowatzki, G1
Strobel, GE1
Bianchi, CP1
Boyd, EM1
Hottenroth, SM1

Reviews

4 reviews available for caffeine and Fever

ArticleYear
Central dopaminergic neurotransmission plays an important role in thermoregulation and performance during endurance exercise.
    European journal of sport science, 2016, Volume: 16, Issue:7

    Topics: Animals; Body Temperature Regulation; Bupropion; Caffeine; Dopamine; Exercise; Female; Fever; Humans

2016
CNS fatigue provoked by prolonged exercise in the heat.
    Frontiers in bioscience (Elite edition), 2010, 01-01, Volume: 2, Issue:2

    Topics: Caffeine; Central Nervous System; Dopamine; Exercise; Fatigue; Fever; Hot Temperature; Humans; Norep

2010
Alterations in central fatigue by pharmacological manipulations of neurotransmitters in normal and high ambient temperature.
    Sports medicine (Auckland, N.Z.), 2010, Mar-01, Volume: 40, Issue:3

    Topics: Animals; Body Temperature; Body Temperature Regulation; Caffeine; Central Nervous System; Central Ne

2010
Caffeine, fluid-electrolyte balance, temperature regulation, and exercise-heat tolerance.
    Exercise and sport sciences reviews, 2007, Volume: 35, Issue:3

    Topics: Adult; Body Temperature Regulation; Caffeine; Dehydration; Exercise; Fever; Humans; Water-Electrolyt

2007

Trials

3 trials available for caffeine and Fever

ArticleYear
[Analgesic, antipyretic and anti-rheumatic activity of 2 preparations evaluated in a multicenter clinical trial].
    La Clinica terapeutica, 1982, Dec-15, Volume: 103, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Child; Child, Preschool; Clinical Trials

1982
[The experience with solpadeine -- a new analgesic].
    Klinicheskaia meditsina, 1997, Volume: 75, Issue:12

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Caffeine; Codeine; Drug Comb

1997
Caffeine as an analgesic adjuvant. A double-blind study comparing aspirin with caffeine to aspirin and placebo in patients with sore throat.
    Archives of internal medicine, 1991, Volume: 151, Issue:4

    Topics: Adult; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Female; Fever; Humans;

1991

Other Studies

32 other studies available for caffeine and Fever

ArticleYear
Cerebellar oxidative stress and fine motor impairment in adolescent rats exposed to hyperthermia-induced seizures is prevented by maternal caffeine intake during gestation and lactation.
    European journal of pharmacology, 2018, Mar-05, Volume: 822

    Topics: 5'-Nucleotidase; Adenosine; Animals; Caffeine; Cerebellum; Female; Fever; Gait; Lactation; Mothers;

2018
Cardiovascular prevention and at-risk behaviours in a large population of amateur rugby players.
    European journal of preventive cardiology, 2019, Volume: 26, Issue:14

    Topics: Adolescent; Adult; Aged; Alcohol Drinking; Athletes; Caffeine; Cardiovascular Diseases; Child; Elect

2019
Malignant hyperthermia in Canada: characteristics of index anesthetics in 129 malignant hyperthermia susceptible probands.
    Anesthesia and analgesia, 2014, Volume: 118, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthetics; Caffeine; Canada; Child; Child, Preschool; Dantrolene; Female;

2014
Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats.
    Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:7

    Topics: Animals; Behavior, Animal; Body Temperature; Brain; Caffeine; Discrimination, Psychological; Dopamin

2016
Mechanisms mediating the ability of caffeine to influence MDMA ('Ecstasy')-induced hyperthermia in rats.
    British journal of pharmacology, 2010, Volume: 160, Issue:4

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adrenergic alpha-Antagonists;

2010
Evaluation of anti-nociceptive, anti-inflammatory and antipyretic activities of Artemisia scoparia hydromethanolic extract.
    Journal of ethnopharmacology, 2013, Jan-09, Volume: 145, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Artemisia; Caffeine; Carrageenan; Edema

2013
Ephedrine plus caffeine causes age-dependent cardiovascular responses in Fischer 344 rats.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5

    Topics: Age Factors; Animals; Body Temperature; Caffeine; Central Nervous System Stimulants; Drug Synergism;

2005
Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA ("Ecstasy") and MDA ("Love").
    Neuropharmacology, 2006, Volume: 50, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Area Under Curve; Behavior, Animal; Body Temperature; Brain

2006
Association of caffeine to MDMA does not increase antinociception but potentiates adverse effects of this recreational drug.
    Brain research, 2006, Sep-21, Volume: 1111, Issue:1

    Topics: Analgesics; Animals; Body Temperature; Brain; Caffeine; Central Nervous System Stimulants; Disease M

2006
Caffeinism. A cause of long-continued, low-grade fever.
    JAMA, 1967, Dec-18, Volume: 202, Issue:12

    Topics: Adult; Body Temperature; Caffeine; Coffee; Female; Fever; Humans

1967
Neuroleptic malignant syndrome and malignant hyperthermia.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:2

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Caffeine; Fever; Fluphenazine; Halothane; Humans; Musc

1983
Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever.
    Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:12

    Topics: Administration, Oral; Animals; Caffeine; Endotoxins; Fever; Injections, Intravenous; Malaria; Male;

1993
Fever from caffeine.
    Allergy, 1996, Volume: 51, Issue:3

    Topics: Caffeine; Cross Reactions; Female; Fever; Humans; Middle Aged; Theophylline

1996
Fulminant malignant hyperthermia associated with ketoacidotic diabetic coma.
    Intensive care medicine, 1996, Volume: 22, Issue:8

    Topics: Adult; Caffeine; Cresols; Dantrolene; Diabetic Coma; Diabetic Ketoacidosis; Fever; Halothane; Humans

1996
HSP72 expression in malignant hyperthermia and normal muscle following exposure to caffeine and halothane.
    Muscle & nerve, 1997, Volume: 20, Issue:1

    Topics: Animals; Caffeine; Fever; Halothane; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Muscle, Skeleta

1997
[The use of the preparation Solpadeine in dental practice].
    Stomatologiia, 1997, Volume: 76, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caff

1997
Caffeine modulates heat shock induced apoptosis in the human promyelocytic leukemia cell line HL-60.
    Cancer letters, 1997, Dec-16, Volume: 121, Issue:1

    Topics: Apoptosis; Caffeine; Dose-Response Relationship, Drug; Fever; Heat-Shock Response; HL-60 Cells; Huma

1997
Induction of cytogenetic damage in human lymphocytes in vitro and of antineoplastic effects in Ehrlich ascites tumor cells in vivo treated by methotrexate, hyperthermia and/or caffeine.
    Mutation research, 1998, Dec-03, Volume: 422, Issue:2

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents; Body Weight; Caffeine; Carcinoma, Ehrlich Tumor;

1998
Mutations to Gly2370, Gly2373 or Gly2375 in malignant hyperthermia domain 2 decrease caffeine and cresol sensitivity of the rabbit skeletal-muscle Ca2+-release channel (ryanodine receptor isoform 1).
    The Biochemical journal, 2001, Nov-15, Volume: 360, Issue:Pt 1

    Topics: Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Caffeine; Ca

2001
[Phenomenology of antipyresis. A study on Fortalidon].
    Die Medizinische Welt, 1977, Dec-09, Volume: 28, Issue:49

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Aspirin; Barbiturates; Caffeine; Codeine; Drug

1977
Effects of methylxanthine drugs on pyrogen-induced hyperthermia.
    European journal of pharmacology, 1977, Oct-15, Volume: 45, Issue:4

    Topics: Animals; Caffeine; Female; Fever; Male; Pyrogens; Rabbits; Shigella dysenteriae; Theophylline; Time

1977
[The antipyretic effect of Lonarid N in children].
    Fortschritte der Medizin, 1979, Apr-05, Volume: 97, Issue:13

    Topics: Acetaminophen; Amobarbital; Caffeine; Child; Child, Preschool; Codeine; Drug Combinations; Drug Eval

1979
[Control of fever using symptomatic measures].
    Anasthesiologische und intensivmedizinische Praxis, 1977, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Analgesics; Antitussive Agents; Caffeine; Child; Child, Presch

1977
[Effect of drugs on the pyrogenic reactivity of sheep].
    Veterinarno-meditsinski nauki, 1978, Volume: 15, Issue:1

    Topics: Alcaligenes; Animals; Atropine; Bromides; Caffeine; Drug Evaluation, Preclinical; Fever; Lipopolysac

1978
Contracture test and histologic and histochemical analyses of muscle biopsy specimens from horses with exertional rhabdomyolysis.
    Journal of the American Veterinary Medical Association, 1990, Apr-01, Volume: 196, Issue:7

    Topics: Anesthesia; Animals; Biopsy, Needle; Caffeine; Contracture; Female; Fever; Halothane; Horse Diseases

1990
[A family study of the caffeine contracture tests on skinned muscle fibers with the propositus affected by exercise-induced hyper-CK-emia].
    Rinsho shinkeigaku = Clinical neurology, 1988, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Caffeine; Creatine Kinase; Exercise; Family; Female; Fever; Humans; Male; Middle

1988
Metabolic error of muscle metabolism after recovery from malignant hyperthermia.
    Lancet (London, England), 1970, Oct-31, Volume: 2, Issue:7679

    Topics: Adolescent; Adult; Anesthesia, General; Caffeine; Calcium; Contracture; Female; Fever; Halothane; Hu

1970
Malignant hyperthermia--an investigation of three patients.
    Annals of the Royal College of Surgeons of England, 1971, Volume: 48, Issue:2

    Topics: Adenosine Triphosphatases; Anesthesia, General; Aspartate Aminotransferases; Body Temperature; Caffe

1971
The effect of caffeine on the antipyretic action of aspirin administered during endotoxin induced fever.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Animals; Aspirin; Caffeine; Endotoxins; Fever; Rabbits

1972
[Thea nigra, a delightful drug].
    Medizinische Klinik, 1967, Mar-31, Volume: 62, Issue:13

    Topics: Caffeine; China; Drug Therapy; Europe; Fever; History, 16th Century; History, 17th Century; History,

1967
An in-vitro model of anesthetic hypertonic hyperpyrexia, halothane--caffeine-induced muscle contractures: prevention of contracture by procainamide.
    Anesthesiology, 1971, Volume: 35, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Anura; Caffeine; Culture Techniques; Drug Synergism; Fever; Halotha

1971
The toxicity of phenacetin at the range of the oral LD50(100 days) in albino rats.
    Toxicology and applied pharmacology, 1968, Volume: 12, Issue:1

    Topics: Animals; Asthenia; Ataxia; Caffeine; Chemical and Drug Induced Liver Injury; Cyanosis; Dehydration;

1968