| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
9,10-dimethyl-1,2-benzanthracene
9,10-Dimethyl-1,2-benzanthracene: Polycyclic aromatic hydrocarbon found in tobacco smoke that is a potent carcinogen.. 7,12-dimethyltetraphene : A tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke. | 2 | 1 | 0 | ortho-fused polycyclic arene;
tetraphenes | carcinogenic agent |
nitroblue tetrazolium
Nitroblue Tetrazolium: Colorless to yellow dye that is reducible to blue or black formazan crystals by certain cells; formerly used to distinguish between nonbacterial and bacterial diseases, the latter causing neutrophils to reduce the dye; used to confirm diagnosis of chronic granulomatous disease. | 2 | 1 | 0 | organic cation | |
brusatol
brusatol: quassinoid from B. javanica; structure | 7.91 | 4 | 0 | triterpenoid | |
bruceine d
bruceine D: from fructus of Brucea javanica (Chinese name Yadanzi). bruceine D : A quassinoid that is 13,20-epoxypicras-3-ene substituted by hydroxy groups at positions 1, 11, 12, 14 and 15 and oxo groups at positions 2 and 16. Isolated from the ethanol extract of the stem of Brucea mollis, it exhibits cytotoxic activity. | 1.99 | 1 | 0 | | |
glaucarubolone
glaucarubolone: a quassinoid which inhibits protein synthesis & DNA synthesis in cells; structure in first source | 2 | 1 | 0 | triterpenoid | |
glycosides
[no description available] | 7.21 | 1 | 0 | | |
bruceantin
[no description available] | 2 | 1 | 0 | triterpenoid | |
glaucarubin
Glaucarubin: (1 beta,2 alpha,11 beta,12 alpha,15 beta(S))-11,20-Epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)picras-3-en-16-one. A quassinoid (Simaroubolide) from Simaruba glauca, a tropical shrub. It has been used as an antiamebic agent and is found to be cytotoxic. It may be of use in cancer chemotherapy. | 2.67 | 3 | 0 | | |