1-(3-chlorophenyl)piperazine has been researched along with Fever in 9 studies
1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These findings demonstrate functional subsensitivity of both 5-HT2A and 5-HT2C receptors mediating hyperthermia following both acute and chronic administration of 5-HT2A/5-HT2C receptor antagonists; some differences in time course and in responses to individual antagonists at 5-HT2A versus 5-HT2C sites were also observed." | 1.30 | Functional subsensitivity of 5-HT2A and 5-HT2C receptors mediating hyperthermia following acute and chronic treatment with 5-HT2A/2C receptor antagonists. ( Aulakh, CS; Mazzola-Pomietto, P; Murphy, DL; Tolliver, T, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (88.89) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Houtepen, LC | 1 |
| Peterse, DP | 1 |
| Westphal, KG | 1 |
| Olivier, B | 1 |
| Vinkers, CH | 1 |
| Mazzola-Pomietto, P | 4 |
| Aulakh, CS | 4 |
| Wozniak, KM | 3 |
| Hill, JL | 2 |
| Murphy, DL | 4 |
| Malinka, W | 1 |
| Tatarczyńska, E | 1 |
| Tolliver, T | 1 |
| Quested, DJ | 1 |
| Sargent, PA | 1 |
| Cowen, PJ | 1 |
| Kłodzińska, A | 1 |
| Chojnacka-Wójcik, E | 1 |
| Lecci, A | 1 |
| Borsini, F | 1 |
| Mancinelli, A | 1 |
| D'Aranno, V | 1 |
| Stasi, MA | 1 |
| Volterra, G | 1 |
| Meli, A | 1 |
1 trial available for 1-(3-chlorophenyl)piperazine and Fever
| Article | Year |
|---|---|
SSRI treatment decreases prolactin and hyperthermic responses to mCPP.
Topics: Adult; Area Under Curve; Body Temperature; Cross-Over Studies; Female; Fever; Humans; Male; Middle A | 1997 |
8 other studies available for 1-(3-chlorophenyl)piperazine and Fever
| Article | Year |
|---|---|
The autonomic stress-induced hyperthermia response is not enhanced by several anxiogenic drugs.
Topics: Animals; Autonomic Nervous System; Body Temperature; Carbolines; Fever; Male; Motor Activity; Pipera | 2011 |
Evidence that 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-induced hyperthermia in rats is mediated by stimulation of 5-HT2A receptors.
Topics: Amphetamines; Animals; Drug Tolerance; Fever; Male; Piperazines; Rats; Rats, Wistar; Serotonin Antag | 1995 |
Evidence that 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane-induced hypophagia and hyperthermia in rats is mediated by serotonin-2A receptors.
Topics: Animals; Body Temperature; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; | 1994 |
Synthesis and pharmacological properties of N-(4-substituted-1-piperazinylalkyl)-1-butyl-2,5-dimethylpyrrole-3,4- dicarboxyimide derivatives.
Topics: Animals; Anticonvulsants; Apomorphine; Central Nervous System Agents; Chemical Phenomena; Chemistry, | 1993 |
Evidence that m-chlorophenylpiperazine-induced hyperthermia in rats is mediated by stimulation of 5-HT2C receptors.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Body Temperature Regulation; Dos | 1996 |
Functional subsensitivity of 5-HT2A and 5-HT2C receptors mediating hyperthermia following acute and chronic treatment with 5-HT2A/2C receptor antagonists.
Topics: Amphetamines; Animals; Body Temperature; Fever; Male; Piperazines; Rats; Rats, Wistar; Receptors, Se | 1997 |
Hyperthermia induced by m-trifluoromethylphenylpiperazine (TFMPP) or m-chlorophenylpiperazine (m-CPP) in heat-adapted rats.
Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Animals; Body Temperature; Dopamine Antagoni | 1992 |
Effect of serotoninergic drugs on stress-induced hyperthermia (SIH) in mice.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Body | 1990 |