Page last updated: 2024-11-03

probenecid and Fever

probenecid has been researched along with Fever in 7 studies

Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
"Fever was induced and maintained for 12 h by injecting Escherichia coli endotoxin (0."5.29The effect of induced fever on the biokinetics of norfloxacin and its interaction with probenecid in goats. ( Jha, K; Roy, BK; Singh, RC, 1996)
"Fever was induced and maintained for 12 h by injecting Escherichia coli endotoxin (0."1.29The effect of induced fever on the biokinetics of norfloxacin and its interaction with probenecid in goats. ( Jha, K; Roy, BK; Singh, RC, 1996)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Gelderen, CJ1
Jha, K1
Roy, BK1
Singh, RC1
Rao, GS1
Ramesh, S1
Ahmad, AH1
Tripathi, HC1
Sharma, LD1
Malik, JK1
Crawford, IL1
Kennedy, JI1
Lipton, JM1
Ojeda, SR1
Sirko, S1
Bishai, I1
Coceani, F1
Tattersall, MH2
Spiers, AS2
Darrell, JH1
Hutchinson, RM1
Gaya, H1

Trials

1 trial available for probenecid and Fever

ArticleYear
'One-visit' therapy for pelvic inflammatory disease.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Aug-09, Volume: 58, Issue:6

    Topics: Acute Disease; Blood Sedimentation; Drug Therapy, Combination; Escherichia coli; Female; Fever; Huma

1980

Other Studies

6 other studies available for probenecid and Fever

ArticleYear
The effect of induced fever on the biokinetics of norfloxacin and its interaction with probenecid in goats.
    Veterinary research communications, 1996, Volume: 20, Issue:5

    Topics: Analysis of Variance; Animals; Drug Interactions; Endotoxins; Escherichia coli; Female; Fever; Goats

1996
Effects of endotoxin-induced fever and probenecid on disposition of enrofloxacin and its metabolite ciprofloxacin after intravascular administration of enrofloxacin in goats.
    Journal of veterinary pharmacology and therapeutics, 2000, Volume: 23, Issue:6

    Topics: Animals; Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Drug Interactions; Endotoxins; Enro

2000
Effects of central administation of probenecid on fevers produced by leukocytic pyrogen and PGE2 in the rabbit.
    The Journal of physiology, 1979, Volume: 287

    Topics: Animals; Body Temperature; Endotoxins; Fever; Injections, Intraventricular; Male; Probenecid; Prosta

1979
Prostaglandin formation in the hypothalamus in vivo: effect of pyrogens.
    The American journal of physiology, 1989, Volume: 256, Issue:3 Pt 2

    Topics: Animals; Body Temperature; Cats; Dinoprostone; Endotoxins; Female; Fever; Hypothalamus; Indomethacin

1989
Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia.
    Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743

    Topics: Administration, Oral; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Bacterial Infections

1972
Empirical antibiotic therapy in febrile patients with neutropenia and malignant disease.
    European journal of cancer, 1973, Volume: 9, Issue:6

    Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Cephalothin; Clindamyci

1973