Page last updated: 2024-10-29

ketamine and Fever

ketamine has been researched along with Fever in 19 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
"Routine premedication with adjunctive anticholinergics should not be considered in paediatric patients receiving ketamine sedation due to the increased risk of fever."9.22Anticholinergic premedication-induced fever in paediatric ambulatory ketamine anaesthesia. ( Choe, WJ; Heo, MH; Kim, JH; Kim, JW; Kim, KT; Kim, KW; Lee, SI; Park, JS, 2016)
"Pretreatment with risperidone (0."5.32Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome. ( Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T, 2004)
"Routine premedication with adjunctive anticholinergics should not be considered in paediatric patients receiving ketamine sedation due to the increased risk of fever."5.22Anticholinergic premedication-induced fever in paediatric ambulatory ketamine anaesthesia. ( Choe, WJ; Heo, MH; Kim, JH; Kim, JW; Kim, KT; Kim, KW; Lee, SI; Park, JS, 2016)
" Both ASP and GLU produced a hyperthermic response in all animals, including those in which hypothermia was induced by reserpine."3.69Effect of aspartate and glutamate on nociception, catalepsy and core temperature in rats. ( Gupta, MC; Singh, J, 1997)
" Analysis of the log dose-response curves for the effects of ketamine and ketamine-magnesium sulfate combination on the baseline body temperature revealed synergistic interaction, and about 5."1.40Synergistic interaction between ketamine and magnesium in lowering body temperature in rats. ( Medić, BM; Prostran, MŠ; Savić Vujović, KR; Srebro, DP; Vučetić, CS; Vučković, SM, 2014)
"Influenza-associated encephalopathy (IAE) is characterized by severe neurological complications during high-grade fever with high morbidity and mortality in children."1.36Rat model of influenza-associated encephalopathy (IAE): studies of electroencephalogram (EEG) in vivo. ( Cissé, Y; Inoue, I; Kido, H; Wang, S, 2010)
"Pretreatment with risperidone (0."1.32Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome. ( Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T, 2004)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's2 (10.53)18.2507
2000's6 (31.58)29.6817
2010's5 (26.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zanos, P1
Highland, JN1
Stewart, BW1
Georgiou, P1
Jenne, CE1
Lovett, J1
Morris, PJ1
Thomas, CJ1
Moaddel, R1
Zarate, CA1
Gould, TD1
Vučković, SM1
Savić Vujović, KR1
Srebro, DP1
Medić, BM1
Vučetić, CS1
Prostran, MŠ2
Barbier, L1
Canini, F1
Giroud, C1
Beaup, C1
Foquin, A1
Maury, R1
Denis, J1
Peinnequin, A1
Dorandeu, F1
Kim, KW1
Choe, WJ1
Kim, JH1
Kim, KT1
Lee, SI1
Park, JS1
Kim, JW1
Heo, MH1
Cissé, Y1
Wang, S1
Inoue, I1
Kido, H1
Nisijima, K1
Shioda, K1
Yoshino, T1
Takano, K1
Kato, S1
McLaren, GW1
Thornton, PD1
Newman, C1
Buesching, CD1
Baker, SE1
Mathews, F1
Macdonald, DW1
Bertollo, CM1
Oliveira, AC1
Rocha, LT1
Costa, KA1
Nascimento, EB1
Coelho, MM1
Posner, LP1
Gleed, RD1
Erb, HN1
Ludders, JW1
Singh, J1
Gupta, MC1
Spelman, LH1
Jochem, WJ1
Summer, PW1
Redmond, DP1
Stoskopf, MK1
Caulkett, NA1
Cribb, PH1
Haigh, JC1
López, KR1
Gibbs, PH1
Reed, DS1
Lees, DE1
Macnamara, T1
Sedgwick, CJ1
Simpson, CW1
Resch, GE1
Bennett, EJ1
Salem, MR1
Marcy, JH1
Hiles, DA1
Kramer, RJ1
Roper, AL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Anticholinergic Premedication Induced Fever in Pediatric Ambulatory Anesthesia With Ketamine[NCT02430272]84 participants (Actual)Interventional2014-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ketamine and Fever

ArticleYear
Pediatric anesthesia.
    Surgery annual, 1974, Volume: 6

    Topics: Anemia; Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesiology; Blood Volume; C

1974
Anesthesia for pediatric ophthalmic operations.
    International ophthalmology clinics, 1973,Summer, Volume: 13, Issue:2

    Topics: Adolescent; Ambulatory Care; Anesthesiology; Atropine; Barbiturates; Brain Diseases; Child; Child, P

1973

Trials

3 trials available for ketamine and Fever

ArticleYear
Anticholinergic premedication-induced fever in paediatric ambulatory ketamine anaesthesia.
    The Journal of international medical research, 2016, Volume: 44, Issue:4

    Topics: Ambulatory Care; Anesthesia; Body Temperature; Child; Child, Preschool; Cholinergic Antagonists; Con

2016
High rectal temperature indicates an increased risk of unexpected recovery in anaesthetized badgers.
    Veterinary anaesthesia and analgesia, 2005, Volume: 32, Issue:1

    Topics: Analgesics; Anesthesia Recovery Period; Anesthesia, General; Animals; Animals, Wild; Body Temperatur

2005
Post-anesthetic hyperthermia in cats.
    Veterinary anaesthesia and analgesia, 2007, Volume: 34, Issue:1

    Topics: Analgesics, Opioid; Anesthesia Recovery Period; Animals; Body Temperature; Cat Diseases; Cats; Femal

2007

Other Studies

14 other studies available for ketamine and Fever

ArticleYear
(
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 03-26, Volume: 116, Issue:13

    Topics: Amino Acids; Animals; Antidepressive Agents; Behavior, Animal; Bridged Bicyclo Compounds, Heterocycl

2019
Synergistic interaction between ketamine and magnesium in lowering body temperature in rats.
    Physiology & behavior, 2014, Mar-29, Volume: 127

    Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Aci

2014
Beneficial effects of a ketamine/atropine combination in soman-poisoned rats under a neutral thermal environment.
    Neurotoxicology, 2015, Volume: 50

    Topics: Animals; Anticonvulsants; Atropine; Body Temperature; Brain; Brain Injuries; Chemical Warfare Agents

2015
Rat model of influenza-associated encephalopathy (IAE): studies of electroencephalogram (EEG) in vivo.
    Neuroscience, 2010, Feb-17, Volume: 165, Issue:4

    Topics: Adrenergic alpha-Agonists; Anesthetics, Dissociative; Animals; Brain; Brain Diseases; Cerebral Corte

2010
Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome.
    Pharmacopsychiatry, 2004, Volume: 37, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Clorgyline; Disease Models, Animal; Dizocilpine Male

2004
Characterization of the antinociceptive and anti-inflammatory activities of riboflavin in different experimental models.
    European journal of pharmacology, 2006, Oct-10, Volume: 547, Issue:1-3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Body Temperature; Carrageenan; Dose

2006
Effect of aspartate and glutamate on nociception, catalepsy and core temperature in rats.
    Indian journal of physiology and pharmacology, 1997, Volume: 41, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Analgesia; Analgesics, Opioid; Animals; Aspartic Acid; Body Temperatur

1997
Postanesthetic monitoring of core body temperature using telemetry in North American river otters (Lutra canadensis).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 1997, Volume: 28, Issue:4

    Topics: Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Body Temperat

1997
Comparative cardiopulmonary effects of carfentanil-xylazine and medetomidine-ketamine used for immobilization of mule deer and mule deer/white-tailed deer hybrids.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2000, Volume: 64, Issue:1

    Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Dissociative; Animal Welfare; Animals; A

2000
A comparison of body temperature changes due to the administration of ketamine-acepromazine and tiletamine-zolazepam anesthetics in cynomolgus macaques.
    Contemporary topics in laboratory animal science, 2002, Volume: 41, Issue:2

    Topics: Acepromazine; Anesthesia, General; Anesthetics, Dissociative; Animals; Body Temperature; Drug Combin

2002
Ketamine-induced hyperthermia--postictal or malignant?
    Anesthesiology, 1977, Volume: 47, Issue:4

    Topics: Anesthesia, Intravenous; Child, Preschool; Diagnosis, Differential; Epilepsy, Tonic-Clonic; Fever; H

1977
Field anesthesia in stressed animals.
    Modern veterinary practice, 1979, Volume: 60, Issue:7

    Topics: Acepromazine; Acidosis; Anesthesia; Animals; Animals, Zoo; Artiodactyla; Diazepam; Etorphine; Fever;

1979
Organization of central hyperthermic mechanisms in helium-cold hypothermic hamsters.
    Brain research bulletin, 1986, Volume: 17, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Biomechanical Phenomena; Body Temperature; Cold Temperature; Crice

1986
Ketamine anesthesia in minor otologic procedures.
    The Laryngoscope, 1971, Volume: 81, Issue:9

    Topics: Adolescent; Anesthesia, General; Anesthesia, Inhalation; Anesthetics; Blood Pressure; Child; Child,

1971