chlorambucil has been researched along with Fever in 10 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with an unusual variant of Sweet's syndrome, in which the course of the disease was chronic and relapsing, was treated successfully with intravenous methylprednisolone (pulse therapy)." | 7.67 | The use of pulse methylprednisolone and chlorambucil in the treatment of Sweet's syndrome. ( Callen, JP; Case, JD; Smith, SZ, 1989) |
| "He developed recurrent skin rash, fever, hypereosinophilia, and acute renal failure after rechallenge with chlorambucil." | 5.35 | Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia. ( Damaj, G; Gruson, B; Makdassi, R; Roszkiewicz, F; Vaida, I, 2009) |
| "A patient with an unusual variant of Sweet's syndrome, in which the course of the disease was chronic and relapsing, was treated successfully with intravenous methylprednisolone (pulse therapy)." | 3.67 | The use of pulse methylprednisolone and chlorambucil in the treatment of Sweet's syndrome. ( Callen, JP; Case, JD; Smith, SZ, 1989) |
| "He developed recurrent skin rash, fever, hypereosinophilia, and acute renal failure after rechallenge with chlorambucil." | 1.35 | Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia. ( Damaj, G; Gruson, B; Makdassi, R; Roszkiewicz, F; Vaida, I, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wootton, F | 1 |
| Glanemann, B | 1 |
| Langley-Hobbs, S | 1 |
| Breheny, C | 1 |
| Fowlie, S | 1 |
| Whitworth, F | 1 |
| Silvestrini, P | 1 |
| Threlfall, A | 1 |
| Sorrell, S | 1 |
| Black, V | 1 |
| Vaida, I | 1 |
| Roszkiewicz, F | 1 |
| Gruson, B | 1 |
| Makdassi, R | 1 |
| Damaj, G | 1 |
| Knauf, WU | 1 |
| Lissichkov, T | 1 |
| Aldaoud, A | 1 |
| Liberati, A | 1 |
| Loscertales, J | 1 |
| Herbrecht, R | 1 |
| Juliusson, G | 1 |
| Postner, G | 1 |
| Gercheva, L | 1 |
| Goranov, S | 1 |
| Becker, M | 1 |
| Fricke, HJ | 1 |
| Huguet, F | 1 |
| Del Giudice, I | 1 |
| Klein, P | 1 |
| Tremmel, L | 1 |
| Merkle, K | 1 |
| Montillo, M | 1 |
| Levin, M | 1 |
| Libster, D | 1 |
| Weber, E | 1 |
| Berger, S | 1 |
| Weber, S | 1 |
| Case, JD | 1 |
| Smith, SZ | 1 |
| Callen, JP | 1 |
| Mead, GM | 1 |
| Williams, CJ | 1 |
| Whitehouse, JM | 1 |
| Ultmann, JE | 1 |
| Nixon, DD | 1 |
| Sawitsky, A | 1 |
| Boklan, BF | 1 |
| Benjamin, Z | 1 |
| Smith, E | 1 |
| Gáspár, IA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Retrospective Multicenter Trial on Efficacy and Toxicity of Bendamustine Alone or Associated With Rituximab, As Salvage Therapy in Patients With Chronic Lymphoproliferative Disorders[NCT01832597] | 109 participants (Actual) | Observational | 2010-11-30 | Completed | |||
| A Phase I/II Study of Bendamustine, Lenalidomide and Low-dose Dexamethasone, (BdL) for the Treatment of Patients With Relapsed Myeloma.[NCT01686386] | Phase 1/Phase 2 | 60 participants (Anticipated) | Interventional | 2010-02-28 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chlorambucil and Fever
| Article | Year |
|---|---|
The therapy of lymphoma.
Topics: Adrenal Cortex Hormones; Asparaginase; Bone Marrow Diseases; Chlorambucil; Cyclophosphamide; Cytarab | 1969 |
1 trial available for chlorambucil and Fever
| Article | Year |
|---|---|
Phase III randomized study of bendamustine compared with chlorambucil in previously untreated patients with chronic lymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Agents; Bendamustine Hydrochloride; Chlorambucil; Disease-Free Survival; | 2009 |
Phase III randomized study of bendamustine compared with chlorambucil in previously untreated patients with chronic lymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Agents; Bendamustine Hydrochloride; Chlorambucil; Disease-Free Survival; | 2009 |
Phase III randomized study of bendamustine compared with chlorambucil in previously untreated patients with chronic lymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Agents; Bendamustine Hydrochloride; Chlorambucil; Disease-Free Survival; | 2009 |
Phase III randomized study of bendamustine compared with chlorambucil in previously untreated patients with chronic lymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Agents; Bendamustine Hydrochloride; Chlorambucil; Disease-Free Survival; | 2009 |
8 other studies available for chlorambucil and Fever
| Article | Year |
|---|---|
Feline non-erosive immune-mediated polyarthritis: a multicentre, retrospective study of 20 cases (2009-2020).
Topics: Animals; Arthritis; Cat Diseases; Cats; Chlorambucil; Cyclosporine; Female; Fever; Immunosuppressive | 2022 |
Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia.
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Aged; Chlorambucil; Drug Eruptions; Eosinophilia; Exan | 2009 |
Allergic reaction to chlorambucil in chronic lymphocytic leukemia presenting with fever and lymphadenopathy.
Topics: Aged; Chlorambucil; Disease Progression; Drug Hypersensitivity; Female; Fever; Humans; Leukemia, Lym | 2005 |
Rapid desensitization for chlorambucil drug fever.
Topics: Aged; Aged, 80 and over; Chlorambucil; Female; Fever; Humans; Male | 2007 |
The use of pulse methylprednisolone and chlorambucil in the treatment of Sweet's syndrome.
Topics: Biopsy; Chlorambucil; Chronic Disease; Dermatitis; Female; Fever; Humans; Methylprednisolone; Middle | 1989 |
Cisplatin, adriamycin and cyclophosphamide (PACe) combination chemotherapy in patients with ovarian carcinoma resistant to chlorambucil.
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Cyclophosphamide; | 1985 |
Drug fever produced by chlorambucil.
Topics: Chlorambucil; Female; Fever; Humans; Leukemia, Lymphoid; Middle Aged | 1971 |
Pentamidine treatment of Pneumocystis carinii pneumonitis in an adult with lymphatic leukemia.
Topics: Antiprotozoal Agents; Audiometry; Chlorambucil; Fever; Humans; Leukemia, Lymphoid; Lymph Nodes; Male | 1968 |