loxoprofen and Fever
loxoprofen has been researched along with Fever in 7 studies
loxoprofen: RN given refers to parent cpd without isomeric designation; structure in first source
loxoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lornoxicam exhibits strong analgesic but weak antipyretic effects in rats with paw inflammation." | 7.75 | The importance of brain PGE2 inhibition versus paw PGE2 inhibition as a mechanism for the separation of analgesic and antipyretic effects of lornoxicam in rats with paw inflammation. ( Arai, I; Futaki, N; Harada, M; Hashimoto, Y; Honma, Y; Hoshi, K; Nakaike, S; Sugimoto, M, 2009) |
| "Lornoxicam exhibits strong analgesic but weak antipyretic effects in rats with paw inflammation." | 3.75 | The importance of brain PGE2 inhibition versus paw PGE2 inhibition as a mechanism for the separation of analgesic and antipyretic effects of lornoxicam in rats with paw inflammation. ( Arai, I; Futaki, N; Harada, M; Hashimoto, Y; Honma, Y; Hoshi, K; Nakaike, S; Sugimoto, M, 2009) |
| " We investigated the effect of such a combination therapy, using the Ephedra herb, which is a common ingredient of Kakkon-to and Mao-to, and Loxoprofen, a nonsteroidal anti-inflammatory drug (NSAID), on fever induced in an experimental model of mice under strong stress." | 3.71 | The combination therapy of Ephedra herb and Loxoprofen caused gastric lesions in mice. ( Aikawa, Y; Cho, S; Cyong, JC; Hong, T; Jin, GB; Miura, M; Yasuno, F; Yoshino, G, 2002) |
| " The anti-inflammatory potency of NS-398 in rat carrageenin-induced edema was as potent as that of indomethacin and 8 times more potent than diclofenac." | 3.68 | NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. ( Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K, 1993) |
| "A detection kit for influenza virus A and B antigens was used to determine the presence of influenza virus infection." | 2.76 | Antipyretic and analgesic effects of zaltoprofen for the treatment of acute upper respiratory tract infection: verification of a noninferiority hypothesis using loxoprofen sodium. ( Azuma, A; Kudoh, S; Nagatake, T; Nakashima, M, 2011) |
| "Infectious mononucleosis is a clinical syndrome most commonly associated with primary Epstein-Barr virus (EBV) infection." | 1.43 | Nonsteroidal Anti-Inflammatory Drugs Quickly Resolve Symptoms Associated with EBV-Induced Infectious Mononucleosis in Patients with Atopic Predispositions. ( Kazama, I; Miura, C; Nakajima, T, 2016) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Terada, A | 1 |
| Naruto, S | 1 |
| Wachi, K | 1 |
| Tanaka, S | 1 |
| Iizuka, Y | 1 |
| Misaka, E | 1 |
| Kazama, I | 2 |
| Senzaki, M | 1 |
| Miura, C | 1 |
| Nakajima, T | 1 |
| Futaki, N | 2 |
| Harada, M | 1 |
| Sugimoto, M | 1 |
| Hashimoto, Y | 1 |
| Honma, Y | 1 |
| Arai, I | 2 |
| Nakaike, S | 1 |
| Hoshi, K | 1 |
| Azuma, A | 1 |
| Kudoh, S | 1 |
| Nakashima, M | 1 |
| Nagatake, T | 1 |
| Cho, S | 1 |
| Hong, T | 1 |
| Jin, GB | 1 |
| Yoshino, G | 1 |
| Miura, M | 1 |
| Aikawa, Y | 1 |
| Yasuno, F | 1 |
| Cyong, JC | 1 |
| Yoshikawa, K | 1 |
| Hamasaka, Y | 1 |
| Higuchi, S | 1 |
| Iizuka, H | 1 |
| Otomo, S | 1 |
Trials
1 trial available for loxoprofen and Fever
| Article | Year |
|---|---|
Antipyretic and analgesic effects of zaltoprofen for the treatment of acute upper respiratory tract infection: verification of a noninferiority hypothesis using loxoprofen sodium.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Benzopyrans; Bod | 2011 |
Other Studies
6 other studies available for loxoprofen and Fever
| Article | Year |
|---|---|
Synthesis and antiinflammatory activity of [(cycloalkylmethyl)phenyl]acetic acids and related compounds.
Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Female; Fever; Ibuprofen; Indomethacin; Inflamma | 1984 |
Does immunosuppressive property of non-steroidal anti-inflammatory drugs (NSAIDs) reduce COVID-19 vaccine-induced systemic side effects?
Topics: Acetaminophen; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; COVID-19 Vaccines; Fati | 2021 |
Nonsteroidal Anti-Inflammatory Drugs Quickly Resolve Symptoms Associated with EBV-Induced Infectious Mononucleosis in Patients with Atopic Predispositions.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Dermatitis, Atopic; Female; Fever; H | 2016 |
The importance of brain PGE2 inhibition versus paw PGE2 inhibition as a mechanism for the separation of analgesic and antipyretic effects of lornoxicam in rats with paw inflammation.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cel | 2009 |
The combination therapy of Ephedra herb and Loxoprofen caused gastric lesions in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Body Weight; Ephedra; | 2002 |
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygena | 1993 |