Compounds > n-acetylmuramyl-alanylglutamine methyl ester
Page last updated: 2024-12-07

n-acetylmuramyl-alanylglutamine methyl ester

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N-acetylmuramyl-alanylglutamine methyl ester: RN given refers to (D)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID133276
SCHEMBL ID18319642
MeSH IDM0125774

Synonyms (8)

Synonym
n-acetylmuramyl-alanylglutamine methyl ester
d-glutamine, n2-(n-(n-acetylmuramoyl)-l-alanyl)-, methyl ester
murametide
79787-27-2
methyl (2r)-2-[[(2s)-2-[2-[(2s,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxypropanoylamino]propanoyl]amino]-5-amino-5-oxopentanoate
SCHEMBL18319642
DTXSID201000734
2-deoxy-2-[(1-hydroxyethylidene)amino]-3-o-[1-hydroxy-1-({1-hydroxy-1-[(5-hydroxy-5-imino-1-methoxy-1-oxopentan-2-yl)imino]propan-2-yl}imino)propan-2-yl]hexopyranose

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Murabutide did not stimulate human or rabbit cells to release endogenous pyrogen (EP), but murametide induced EP production at the same dosage levels as MDP."( Inhibition of endogenous pyrogen-induced fever by a muramyl dipeptide derivative.
Chedid, L; Parant, F; Parant, M; Riveau, G, 1984)		0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.18

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.18 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.38 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.18)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
murabutide
murabutide: adjuvant devoid of pyrogenicity		3.2260
ConditionIndicatedRelationship StrengthStudiesTrials
Pyrexia
[description not available]		02.6630
Fever
An abnormal elevation of body temperature, usually as a result of a pathologic process.		02.6630
Cardiovirus Infections
Infections caused by viruses of the genus CARDIOVIRUS, family PICORNAVIRIDAE.		01.9910
Hepatitis, Viral, Animal
INFLAMMATION of the LIVER in animals due to viral infection.		01.9710