6-o-stearoyl-n-acetylmuramyl-alanylisoglutamine profile

ID Source	ID
PubMed CID	124703
MeSH ID	M0108270

Synonym
6-smdp
(2r)-2-[[(2s)-2-[2-[(2s,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(octadecanoyloxymethyl)oxan-4-yl]oxypropanoylamino]propanoyl]amino]-5-amino-5-oxopentanoic acid
d-alpha-glutamine, n2-(n-(n-acetyl-6-o-(1-oxooctadecyl)muramoyl)-l-alanyl)-
6-o-stearoyl-muramyl dipeptide
6-o-stearoyl-n-acetylmuramyl-alanylisoglutamine
l18-mdp(ala)
6-o-stearoyl-n-acmu-ala-iso-gln

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	11 (64.71)	18.7374
1990's	2 (11.76)	18.2507
2000's	0 (0.00)	29.6817
2010's	4 (23.53)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	1 (5.88%)	5.53%
Reviews	1 (5.88%)	6.00%
Case Studies	2 (11.76%)	4.05%
Observational	0 (0.00%)	0.25%
Other	13 (76.47%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
acetic acid Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed). acetic acid : A simple monocarboxylic acid containing two carbons.	2.06	1	0	monocarboxylic acid	antimicrobial food preservative; Daphnia magna metabolite; food acidity regulator; protic solvent
lauryl methacrylate dodecyl methacrylate: monomer unit of various acrylate polymers used to form gels,plastics and some biocompatible materials; structure in first source	2.13	1	0
mannose mannopyranose : The pyranose form of mannose.	2.13	1	0	D-aldohexose; D-mannose; mannopyranose	metabolite
fr 41565 heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine: synthetic cpd; also immunoactive peptide isolated from Streptomyces active against multiplication of HSV-1 & HSV-2 virus	2.06	1	0
fk 156 FK 156: structure given in first source; RN given refers to ((L)(R)-isomer	2.06	1	0
technetium tc 99m (sn)methylenediphosphonate [no description available]	3.38	1	1
cortisone [no description available]	1.96	1	0	11-oxo steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	human metabolite; mouse metabolite
diaminopimelic acid Diaminopimelic Acid: A diamino derivative of heptanedioic acid with amino groups at C-2 and C-6 and the general formula (COOH)CH(NH2)CH2CH2CH2CH(NH2)(COOH).. LL-2,6-diaminopimelic acid : A 2,6-diaminopimelic acid in which both chiral centres have S configuration. It is a component of bacterial cell wall.	2.06	1	0	2,6-diaminopimelic acid; amino acid zwitterion	Escherichia coli metabolite
dinoprostone prostaglandin E2 : Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.	1.96	1	0	prostaglandins E	human metabolite; mouse metabolite; oxytocic
naloxone Naloxone: A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.. naloxone : A synthetic morphinane alkaloid that is morphinone in which the enone double bond has been reduced to a single bond, the hydrogen at position 14 has been replaced by a hydroxy group, and the methyl group attached to the nitrogen has been replaced by an allyl group. A specific opioid antagonist, it is used (commonly as its hydrochloride salt) to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known or suspected opioid overdose.	2.06	1	0	morphinane alkaloid; organic heteropentacyclic compound; tertiary alcohol	antidote to opioid poisoning; central nervous system depressant; mu-opioid receptor antagonist
morphine Meconium: The thick green-to-black mucilaginous material found in the intestines of a full-term fetus. It consists of secretions of the INTESTINAL GLANDS; BILE PIGMENTS; FATTY ACIDS; AMNIOTIC FLUID; and intrauterine debris. It constitutes the first stools passed by a newborn.	1.97	1	0	morphinane alkaloid; organic heteropentacyclic compound; tertiary amino compound	anaesthetic; drug allergen; environmental contaminant; geroprotector; mu-opioid receptor agonist; opioid analgesic; plant metabolite; vasodilator agent; xenobiotic
romurtide romurtide: a synthetic muramyl dipeptide analog; stimulates chemotactic mobility, phagocytic activity & superoxide production by neutrophils in mice; used for the prophylaxis of leukocytopenia during radiation therapy; structure given in first source	2.4	2	0	organic molecular entity
saf-m [no description available]	1.97	1	0
technetium tc 99m medronate Technetium Tc 99m Medronate: A gamma-emitting radionuclide imaging agent used primarily in skeletal scintigraphy. Because of its absorption by a variety of tumors, it is useful for the detection of neoplasms.	3.38	1	1

Condition	Relationship Strength	Studies	Trials
Antibody Deficiency Syndrome [description not available]	2.1	1	0
Immunologic Deficiency Syndromes Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral.	2.1	1	0
Genetic Diseases, X-Chromosome Linked [description not available]	2.11	1	0
Erythema Nodosum An erythematous eruption commonly associated with drug reactions or infection and characterized by inflammatory nodules that are usually tender, multiple, and bilateral. These nodules are located predominantly on the shins with less common occurrence on the thighs and forearms. They undergo characteristic color changes ending in temporary bruise-like areas. This condition usually subsides in 3-6 weeks without scarring or atrophy.	2.11	1	0
Duncan Disease [description not available]	2.11	1	0
Viral Diseases [description not available]	2.11	1	0
Bowel Diseases, Inflammatory [description not available]	2.11	1	0
Lymphoproliferative Disorders Disorders characterized by proliferation of lymphoid tissue, general or unspecified.	2.11	1	0
Virus Diseases A general term for diseases caused by viruses.	2.11	1	0
Inflammatory Bowel Diseases Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.	2.11	1	0
Ache [description not available]	2.06	1	0
Pain An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.	2.06	1	0
Bone Loss, Osteoclastic [description not available]	1.96	1	0
Adenocarcinoma, Basal Cell [description not available]	1.96	1	0
Breast Cancer [description not available]	1.96	1	0
Adenocarcinoma A malignant epithelial tumor with a glandular organization.	1.96	1	0
Breast Neoplasms Tumors or cancer of the human BREAST.	1.96	1	0
Corynebacterium Infections Infections with bacteria of the genus CORYNEBACTERIUM.	1.96	1	0
Candida Infection [description not available]	2.36	2	0
E coli Infections [description not available]	2.36	2	0
Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.	1.96	1	0
Candidiasis Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)	2.36	2	0
Escherichia coli Infections Infections with bacteria of the species ESCHERICHIA COLI.	2.36	2	0
Bacterial Disease [description not available]	1.96	1	0
Infections, Klebsiella [description not available]	1.96	1	0
Infections, Listeria [description not available]	1.96	1	0
Infections, Staphylococcal [description not available]	1.96	1	0
Bacterial Infections Infections by bacteria, general or unspecified.	1.96	1	0
Klebsiella Infections Infections with bacteria of the genus KLEBSIELLA.	1.96	1	0
Staphylococcal Infections Infections with bacteria of the genus STAPHYLOCOCCUS.	1.96	1	0
Experimental Lung Inflammation Inflammation of any part, segment or lobe, of the lung parenchyma.	1.96	1	0
Infections, Pseudomonas [description not available]	1.96	1	0
Pneumonia Infection of the lung often accompanied by inflammation.	1.96	1	0
Pseudomonas Infections Infections with bacteria of the genus PSEUDOMONAS.	1.96	1	0
Chronic Illness [description not available]	3.38	1	1
Mandibular Diseases Diseases involving the MANDIBLE.	3.38	1	1
Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).	3.38	1	1
Osteomyelitis INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA.	3.38	1	1
Pyrexia [description not available]	1.97	1	0
Drug Withdrawal Symptoms [description not available]	1.97	1	0
Fever An abnormal elevation of body temperature, usually as a result of a pathologic process.	1.97	1	0
Substance Withdrawal Syndrome Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.	1.97	1	0
Experimental Neoplasms [description not available]	1.96	1	0

6-o-stearoyl-n-acetylmuramyl-alanylisoglutamine

Cross-References

Synonyms (7)

Research

Studies (17)

Market Indicators

Research Demand Index: 11.20

Study Types

6-o-stearoyl-n-acetylmuramyl-alanylisoglutamine

Cross-References

Synonyms (7)

Research

Studies (17)

Market Indicators

Research Demand Index: 11.20

Study Types

Related Drugs (14)

Related Conditions (43)