forsythiaside has been researched along with Fever* in 1 studies
1 other study(ies) available for forsythiaside and Fever
| Article | Year |
|---|---|
Forsythoside A exerts antipyretic effect on yeast-induced pyrexia mice via inhibiting transient receptor potential vanilloid 1 function.
Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel gated by noxious heat, playing major roles in thermoregulation. Forsythoside A (FT-A) is the most abundant phenylethanoid glycosides in Fructus Forsythiae, which has been prescribed as a medicinal herb for treating fever in China for a long history. However, how FT-A affects pyrexia and what is the underlying molecular mechanism remain largely unknown. Here we found that FT-A exerted apparent antipyretic effect through decreasing the levels of prostaglandin E Topics: Animals; Antipyretics; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Fever; Flow Cytometry; Ganglia, Spinal; Glycosides; HEK293 Cells; Humans; Hypothalamus; Immunohistochemistry; Interleukin-8; Mice; Saccharomyces cerevisiae; TRPV Cation Channels | 2017 |