pyrimethamine has been researched along with Fever in 39 studies
Maloprim: contains above 2 cpds
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study examined the efficacy of chloroquine (CQ), amodiaquine (AQ) and sulphadoxine-pyrimethamine (SP) for the treatment of uncomplicated Plasmodium falciparum malaria in Ghana." | 5.11 | A randomized comparative study of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Ghana. ( Amankwa, J; Ansah, NA; Ansah, P; Anto, F; Anyorigiya, T; Atuguba, F; Hodgson, A; Mumuni, G; Oduro, AR, 2005) |
| "We conducted two randomized clinical trials to determine the in vivo efficacy of amodiaquine and sulfadoxine/pyrimethamine in treating Plasmodium falciparum malaria." | 5.09 | In vivo efficacy study of amodiaquine and sulfadoxine/ pyrimethamine in Kibwezi, Kenya and Kigoma, Tanzania. ( Ashruf, G; Bennebroek, J; Gikunda, S; Gorissen, E; Kager, PA; Lamboo, M; Mbaruku, G, 2000) |
| "We have previously shown that both chloroquine and paracetamol (acetaminophen) have antipyretic activity during treatment of acute uncomplicated Plasmodium falciparum malaria in children 1-4 years old." | 3.73 | Relationship between antipyretic effects and cytokine levels in uncomplicated falciparum malaria during different treatment regimes. ( Björkman, A; Hugosson, E; Montgomery, SM; Premji, Z; Troye-Blomberg, M, 2006) |
| "Febrile adults with Plasmodium falciparum parasitemia were treated with sulfadoxine-pyrimethamine and were monitored for 28 days." | 3.73 | HIV immunosuppression and antimalarial efficacy: sulfadoxine-pyrimethamine for the treatment of uncomplicated malaria in HIV-infected adults in Siaya, Kenya. ( Bloland, PB; Hamel, MJ; Kain, KC; Obonyo, CO; Shah, SN; Slutsker, L; Smith, EE, 2006) |
| " Adverse events and clinical and parasitological outcomes were recorded." | 2.73 | A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda. ( D'Alessandro, U; Fanello, CI; Karema, C; Ngamije, D; van Doren, W; Van Overmeir, C, 2007) |
| "5% improvement in the accumulated proportion of patients (1) treated, (2) treated within 24h of illness onset, (3) treated with the recommended antimalarials, (4) treated at an adequate dosage and (5) treated for the correct duration." | 2.73 | Home-based management of fever and malaria treatment practices in Uganda. ( Nsungwa-Sabiiti, J; Ogwal-Okeng, J; Pariyo, G; Peterson, S; Petzold, MG; Tomson, G, 2007) |
| "Malaria is a major cause of death among children in many parts of the world, even though simple and effective treatments exist." | 1.31 | Patterns of care for childhood malaria in Zambia. ( Baume, C; Helitzer, D; Kachur, SP, 2000) |
| "Fever was the only clinical manifestation attributable to parasitemia and only when the parasite density was > or = 5000/microL." | 1.29 | Impact of transmission intensity and age on Plasmodium falciparum density and associated fever: implications for malaria vaccine trial design. ( Bales, JD; Beadle, C; Beier, JC; Chumo, DK; Hoffman, SL; McElroy, PD; Oloo, AJ; Onyango, FK; Oster, CN; Sherwood, JA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (25.64) | 18.7374 |
| 1990's | 4 (10.26) | 18.2507 |
| 2000's | 20 (51.28) | 29.6817 |
| 2010's | 5 (12.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Petersen, E | 1 |
| Marbiah, NT | 1 |
| Magbiti, E | 1 |
| Lines, JD | 1 |
| Maude, GH | 1 |
| Høgh, B | 1 |
| Curtis, C | 1 |
| Greenwood, B | 1 |
| Bradley, D | 1 |
| Bisoffi, Z | 1 |
| Tinto, H | 1 |
| Sirima, BS | 1 |
| Gobbi, F | 1 |
| Angheben, A | 1 |
| Buonfrate, D | 1 |
| Van den Ende, J | 1 |
| Sobanski, V | 1 |
| Ajzenberg, D | 1 |
| Delhaes, L | 1 |
| Bautin, N | 1 |
| Just, N | 1 |
| Jedari, AS | 1 |
| Maliky, Z | 1 |
| Daneshjou, Kh | 1 |
| Nahum, A | 2 |
| Erhart, A | 2 |
| Ahounou, D | 1 |
| Bonou, D | 1 |
| Van Overmeir, C | 3 |
| Menten, J | 2 |
| Akogbeto, M | 2 |
| Coosemans, M | 2 |
| Massougbodji, A | 2 |
| D'Alessandro, U | 3 |
| Elmardi, KA | 1 |
| Malik, EM | 1 |
| Abdelgadir, T | 1 |
| Ali, SH | 1 |
| Elsyed, AH | 1 |
| Mudather, MA | 1 |
| Elhassan, AH | 1 |
| Adam, I | 1 |
| Seboxa, T | 1 |
| Mao, P | 1 |
| Pinchouk, N | 1 |
| Anbessie, J | 1 |
| Alemu, H | 1 |
| Diro, E | 1 |
| Shaukat, AM | 1 |
| Gilliams, EA | 1 |
| Kenefic, LJ | 1 |
| Laurens, MB | 1 |
| Dzinjalamala, FK | 1 |
| Nyirenda, OM | 1 |
| Thesing, PC | 1 |
| Jacob, CG | 1 |
| Molyneux, ME | 1 |
| Taylor, TE | 1 |
| Plowe, CV | 1 |
| Laufer, MK | 1 |
| LAHA, PN | 1 |
| SINGHAL, RN | 1 |
| NAVANI, H | 1 |
| YOUNG, MD | 1 |
| BURGESS, RW | 1 |
| Oduro, AR | 1 |
| Anyorigiya, T | 1 |
| Hodgson, A | 1 |
| Ansah, P | 1 |
| Anto, F | 1 |
| Ansah, NA | 1 |
| Atuguba, F | 1 |
| Mumuni, G | 1 |
| Amankwa, J | 1 |
| Oduro-Boatey, C | 1 |
| Rodrigues, O | 1 |
| Sowunmi, A | 2 |
| Fehintola, FA | 2 |
| Adedeji, AA | 2 |
| Gbotosho, GO | 1 |
| Tambo, E | 1 |
| Fateye, BA | 1 |
| Happi, TC | 1 |
| Oduola, AM | 2 |
| Patrick Kachur, S | 1 |
| Schulden, J | 1 |
| Goodman, CA | 1 |
| Kassala, H | 1 |
| Elling, BF | 1 |
| Khatib, RA | 1 |
| Causer, LM | 1 |
| Mkikima, S | 1 |
| Abdulla, S | 1 |
| Bloland, PB | 2 |
| Shen, WJ | 1 |
| Thiero, M | 1 |
| Hugosson, E | 1 |
| Montgomery, SM | 1 |
| Premji, Z | 1 |
| Troye-Blomberg, M | 1 |
| Björkman, A | 1 |
| Fanello, CI | 1 |
| Karema, C | 1 |
| van Doren, W | 1 |
| Ngamije, D | 1 |
| Shah, SN | 1 |
| Smith, EE | 1 |
| Obonyo, CO | 1 |
| Kain, KC | 1 |
| Slutsker, L | 1 |
| Hamel, MJ | 1 |
| Nsabagasani, X | 1 |
| Källander, K | 1 |
| Peterson, S | 2 |
| Pariyo, G | 2 |
| Tomson, G | 2 |
| Conteh, L | 1 |
| Stevens, W | 1 |
| Wiseman, V | 1 |
| Nsungwa-Sabiiti, J | 1 |
| Ogwal-Okeng, J | 1 |
| Petzold, MG | 1 |
| Gazard, D | 1 |
| Agbowai, C | 1 |
| van Loen, H | 1 |
| Beadle, C | 1 |
| McElroy, PD | 1 |
| Oster, CN | 1 |
| Beier, JC | 1 |
| Oloo, AJ | 1 |
| Onyango, FK | 1 |
| Chumo, DK | 1 |
| Bales, JD | 1 |
| Sherwood, JA | 1 |
| Hoffman, SL | 1 |
| Barat, L | 1 |
| Chipipa, J | 1 |
| Kolczak, M | 1 |
| Sukwa, T | 1 |
| Falade, AG | 1 |
| Falade, CO | 1 |
| Akinyinka, OO | 1 |
| Gorissen, E | 1 |
| Ashruf, G | 1 |
| Lamboo, M | 1 |
| Bennebroek, J | 1 |
| Gikunda, S | 1 |
| Mbaruku, G | 1 |
| Kager, PA | 1 |
| Baume, C | 1 |
| Helitzer, D | 1 |
| Kachur, SP | 1 |
| Tjitra, E | 1 |
| Suprianto, S | 1 |
| Currie, BJ | 1 |
| Morris, PS | 1 |
| Saunders, JR | 1 |
| Anstey, NM | 1 |
| Tarimo, DS | 1 |
| Minjas, JN | 1 |
| Bygbjerg, IC | 1 |
| Ansdell, VE | 1 |
| Wright, SG | 1 |
| Hutchinson, DB | 1 |
| Okuonghae, HO | 1 |
| Nwankwo, MU | 1 |
| Offor, E | 1 |
| Groth, H | 1 |
| Rhyner, K | 1 |
| Vetter, W | 1 |
| Akinyanju, O | 1 |
| Goddell, JC | 1 |
| Ahmed, I | 1 |
| Hall, AP | 1 |
| Ebisawa, I | 1 |
| Komoriya, T | 1 |
| Kimura, M | 1 |
| Muto, T | 1 |
| Berman, SJ | 1 |
| Walker, AJ | 1 |
| Lopez-Antunano, FJ | 1 |
| Sheehy, TW | 1 |
| Reba, RC | 1 |
| Parks, GR | 1 |
12 trials available for pyrimethamine and Fever
| Article | Year |
|---|---|
Controlled trial of lambda-cyhalothrin impregnated bed nets and Maloprim chemosuppression to control malaria in children living in a holoendemic area of Sierra Leone, west Africa. Study design and preliminary results.
Topics: Animals; Anopheles; Bedding and Linens; Child; Child, Preschool; Dapsone; Double-Blind Method; Drug | 1993 |
Extended high efficacy of the combination sulphadoxine-pyrimethamine with artesunate in children with uncomplicated falciparum malaria on the Benin coast, West Africa.
Topics: Analysis of Variance; Animals; Antimalarials; Artemisinins; Artesunate; Benin; Child, Preschool; Coh | 2009 |
A randomized comparative study of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Ghana.
Topics: Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Female; Fever; Ghana; | 2005 |
Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Com | 2005 |
[Coartem and fansimef in the treatment of falciparum malaria].
Topics: Abdominal Pain; Adolescent; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, P | 2006 |
A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschoo | 2007 |
Home-based management of fever and malaria treatment practices in Uganda.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Services; Drug Combinations; D | 2007 |
Adding artesunate to sulphadoxine-pyrimethamine greatly improves the treatment efficacy in children with uncomplicated falciparum malaria on the coast of Benin, West Africa.
Topics: Analysis of Variance; Anemia; Animals; Antimalarials; Artemisinins; Artesunate; Benin; Child, Presch | 2007 |
Comparative efficacy of chloroquine plus chlorpheniramine alone and in a sequential combination with sulfadoxine-pyrimethamine, for the treatment of acute, uncomplicated, falciparum malaria in children.
Topics: Animals; Antimalarials; Antipruritics; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug | 2000 |
In vivo efficacy study of amodiaquine and sulfadoxine/ pyrimethamine in Kibwezi, Kenya and Kigoma, Tanzania.
Topics: Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Drug Resistance, Microbial; Female; Fe | 2000 |
Therapy of uncomplicated falciparum malaria: a randomized trial comparing artesunate plus sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine alone in Irian Jaya, Indonesia.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemisini | 2001 |
Sulfadoxine-pyrimethamine monotherapy in Tanzanian children gives rapid parasite clearance but slow fever clearance that is improved by chloroquine in combination therapy.
Topics: Acetaminophen; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Dru | 2002 |
27 other studies available for pyrimethamine and Fever
| Article | Year |
|---|---|
Should malaria treatment be guided by a point of care rapid test? A threshold approach to malaria management in rural Burkina Faso.
Topics: Adult; Amodiaquine; Antimalarials; Burkina Faso; Child, Preschool; Decision Making; Drug Combination | 2013 |
Severe toxoplasmosis in immunocompetent hosts: be aware of atypical strains.
Topics: Antiprotozoal Agents; Dyspnea; Fever; Humans; Immunocompromised Host; Male; Middle Aged; Pyrimethami | 2013 |
FDA investigation focuses on compounded drugs.
Topics: Animals; Drug Approval; Drug Compounding; Encephalomyelitis; Fever; Horse Diseases; Horses; Off-Labe | 2014 |
A 10 month old infant with nystagmus and strabismus.
Topics: Brain; Electroencephalography; Eye Movements; Fever; Humans; Infant; Leucovorin; Male; Nystagmus, Pa | 2008 |
Feasibility and acceptability of home-based management of malaria strategy adapted to Sudan's conditions using artemisinin-based combination therapy and rapid diagnostic test.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Artemisinins; Community Health W | 2009 |
Artemether-Lumefantrin (Coartem) and artesunate with sulfadoxine-pyrimethamine therapeutic efficacy in the treatment of uncomplicated malaria at Gilgel Gibe II (GGII) South-Western Ethiopia.
Topics: Adolescent; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Chil | 2010 |
Clinical manifestations of new versus recrudescent malaria infections following anti-malarial drug treatment.
Topics: Anemia; Antimalarials; Child; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Fever; | 2012 |
Drug fever, leucocyte counts, erythrocyte sedimentation rate and urine after pyrimethamine (daraprim).
Topics: Antimalarials; Blood Sedimentation; Body Fluids; Fever; Hematologic Tests; Humans; Leukocyte Count; | 1953 |
Pyrimethamine resistance in Plasmodium vivax malaria.
Topics: Antimalarials; Blood Transfusion; Fever; Humans; Malaria; Malaria, Vivax; Plasmodium falciparum; Pyr | 1959 |
Stevens-Johnson syndrome in two children in Ghana following anti-malarial treatment.
Topics: Antimalarials; Child; Drug Combinations; Female; Fever; Ghana; Humans; Malaria, Falciparum; Male; Py | 2005 |
Prevalence of malaria parasitemia among clients seeking treatment for fever or malaria at drug stores in rural Tanzania 2004.
Topics: Adult; Amodiaquine; Analgesics, Non-Narcotic; Anemia; Antimalarials; Child, Preschool; Drug Combinat | 2006 |
Relationship between antipyretic effects and cytokine levels in uncomplicated falciparum malaria during different treatment regimes.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antimalarials; Child, Preschool; Chloroquine; Cyto | 2006 |
HIV immunosuppression and antimalarial efficacy: sulfadoxine-pyrimethamine for the treatment of uncomplicated malaria in HIV-infected adults in Siaya, Kenya.
Topics: Adult; Anemia; Antimalarials; CD4 Lymphocyte Count; Drug Combinations; Female; Fever; HIV Infections | 2006 |
Home-based management of fever in rural Uganda: community perceptions and provider opinions.
Topics: Adolescent; Adult; Antimalarials; Child, Preschool; Chloroquine; Community Health Services; Communit | 2007 |
The role of communication between clients and health care providers: implications for adherence to malaria treatment in rural Gambia.
Topics: Antimalarials; Attitude to Health; Child; Child, Preschool; Chloroquine; Communication Barriers; Dru | 2007 |
Impact of transmission intensity and age on Plasmodium falciparum density and associated fever: implications for malaria vaccine trial design.
Topics: Age Factors; Animals; Anopheles; Antimalarials; Child; Child, Preschool; Clinical Trials as Topic; C | 1995 |
Does the availability of blood slide microscopy for malaria at health centers improve the management of persons with fever in Zambia?
Topics: Ambulatory Care Facilities; Animals; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations | 1999 |
Patterns of care for childhood malaria in Zambia.
Topics: Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Female; Fever; Health Care Surveys; | 2000 |
Megaloblastic anaemia associated with combined pyrimethamine and co-trimoxazole administration.
Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Drug Combinations; Drug Therapy, Combination; Fema | 1976 |
Malarial parasitaemia in febrile children with sickle cell anaemia.
Topics: Adolescent; Anemia, Sickle Cell; Bacteremia; Child; Child, Preschool; Female; Fever; Gram-Negative B | 1992 |
[Pruritus, exanthema, icterus and fever].
Topics: Antimalarials; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Combinations; Exanthema; Fe | 1987 |
Pyrimethamine poisoning.
Topics: Anemia, Macrocytic; Ataxia; Blindness; Central Nervous System; Child, Preschool; Deafness; Female; F | 1973 |
Recrudescent falciparum malaria in Vietnam.
Topics: Adult; Black People; Dapsone; Fever; Follow-Up Studies; Humans; Malaria; Male; Military Medicine; Pl | 1973 |
Morphologic and clinical effect of pyrimethamine-sulfonamide combinations (sulformethoxine-pyrimethamine or sulfamonomethoxine-pyrimethamine) on P. vivax and its infection.
Topics: Adolescent; Adult; Child; Drug Combinations; Female; Fever; Humans; Malaria; Male; Middle Aged; Ovum | 1974 |
Chloroquine-pyrimethamine-sulfisoxazole therapy of Plasmodium falciparum malaria. An alternative to quinine.
Topics: Chloroquine; Dapsone; Drug Resistance, Microbial; Fever; Humans; Malaria; Male; Military Medicine; P | 1969 |
Response to drugs of South American strains of Plasmodium falciparum.
Topics: Chloroquine; Drug Resistance, Microbial; Drug Synergism; Fever; Humans; Malaria; Plasmodium falcipar | 1968 |
Combined pyrimethamine-quinine therapy for chloroquine-resistant P. falciparum infections.
Topics: Adolescent; Adult; Agranulocytosis; Anemia, Hemolytic; Chloroquine; Clinical Laboratory Techniques; | 1969 |