cimetidine has been researched along with Fever in 26 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study showed that both drug regimens are significantly effective in preventing febrile attacks in PFAPA syndrome, and the presence of a MEFV gene mutation might not be the only significant risk factor for a response to colchicine." | 9.51 | Colchicine versus cimetidine: the better choice for Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome prophylaxis, and the role of MEFV gene mutations. ( Asna Ashari, K; Mousavi T, M; Raeeskarami, SR; Sadeghi, P; Vahedi, M; Ziaee, V, 2022) |
| "Cimetidine, as an immunomodulating agent, appears to be beneficial in the in-depth treatment of (P)FAPA syndrome." | 7.70 | [(P)FAPA syndrome: value of cimetidine]. ( Ansoborlo, S; Carrère, A; Guillard, JM; Perel, Y; Pillet, P, 2000) |
| "Cimetidine is a rare cause of drug-induced fever." | 7.67 | Cimetidine-induced fever. ( Landolfo, K; Low, DE; Rogers, AG, 1984) |
| "A 54-year-old bed-bound multiple sclerosis patient experienced fever, mental confusion, and marginal serum creatinine elevations after receiving cimetidine and subsequently ranitidine therapy." | 7.67 | Fever after cimetidine and ranitidine. ( Byrne, EB; Lebovitz, S; Potter, HP, 1986) |
| "This study showed that both drug regimens are significantly effective in preventing febrile attacks in PFAPA syndrome, and the presence of a MEFV gene mutation might not be the only significant risk factor for a response to colchicine." | 5.51 | Colchicine versus cimetidine: the better choice for Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome prophylaxis, and the role of MEFV gene mutations. ( Asna Ashari, K; Mousavi T, M; Raeeskarami, SR; Sadeghi, P; Vahedi, M; Ziaee, V, 2022) |
| "The use of antibiotics and cimetidine in PFAPA syndrome are ineffective." | 4.86 | PFAPA syndrome in children: A meta-analysis on surgical versus medical treatment. ( Athanasopoulos, I; Houlakis, M; Koudoumnakis, E; Parpounas, K; Peridis, S; Pilgrim, G, 2010) |
| "Cimetidine, as an immunomodulating agent, appears to be beneficial in the in-depth treatment of (P)FAPA syndrome." | 3.70 | [(P)FAPA syndrome: value of cimetidine]. ( Ansoborlo, S; Carrère, A; Guillard, JM; Perel, Y; Pillet, P, 2000) |
| "Cimetidine is a rare cause of drug-induced fever." | 3.67 | Cimetidine-induced fever. ( Landolfo, K; Low, DE; Rogers, AG, 1984) |
| "A 54-year-old bed-bound multiple sclerosis patient experienced fever, mental confusion, and marginal serum creatinine elevations after receiving cimetidine and subsequently ranitidine therapy." | 3.67 | Fever after cimetidine and ranitidine. ( Byrne, EB; Lebovitz, S; Potter, HP, 1986) |
| "A 67-year-old man with a bleeding ulcer developed fever, thrombocytopenia, and neutropenia with eosinophilia coincidental to receiving 3600 mg of cimetidine." | 3.66 | Cimetidine and hematologic suppression: things are not always as they appear. ( Castell, DO; Gerhardt, DC; Pasquale, DN; Richter, JE, 1980) |
| "Cimetidine therapy was associated with the resolution of the fevers in 7/26 (27%) patients; tonsillectomy was associated with the resolution of the fevers in 11/11 (100%) patients." | 2.46 | A clinical review of 105 patients with PFAPA (a periodic fever syndrome). ( Feder, HM; Salazar, JC, 2010) |
| "PFAPA or Marshall's syndrome is characterized by abrupt onset of periodic episodes of high fever accompanied by aphthous stomatitis, pharyngitis and cervical adenitis, often associated with headache and / or abdominal or joint pain." | 2.44 | Oral aphthous-like lesions, PFAPA syndrome: a review. ( Buonaiuto, C; Cirillo, N; Femiano, F; Gombos, F; Lanza, A, 2008) |
| "Pharyngitis is the most frequent symptom associated with fever." | 1.72 | Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome: Clinical characteristics and treatment outcomes - a single center study in Japan. ( Kawano, Y; Ohnishi, T; Sato, S; Suganuma, E; Uejima, Y, 2022) |
| " If an underlying problem requires long-term immunosuppressive medication, it is wiser to choose cimetidine rather than increasing the steroid dosage to resolve atypical PFAPA." | 1.30 | PFAPA syndrome (Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis). ( Chen, LC; Huang, JL; Lee, KF; Lee, WI; Lin, SJ; Yang, MH; Yeh, KW, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (38.46) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Raeeskarami, SR | 1 |
| Sadeghi, P | 1 |
| Vahedi, M | 1 |
| Asna Ashari, K | 1 |
| Mousavi T, M | 1 |
| Ziaee, V | 1 |
| Ohnishi, T | 1 |
| Sato, S | 1 |
| Uejima, Y | 1 |
| Kawano, Y | 1 |
| Suganuma, E | 1 |
| Amarilyo, G | 1 |
| Rothman, D | 1 |
| Manthiram, K | 1 |
| Edwards, KM | 1 |
| Li, SC | 1 |
| Marshall, GS | 1 |
| Yildirim-Toruner, C | 1 |
| Haines, K | 1 |
| Ferguson, PJ | 1 |
| Lionetti, G | 1 |
| Cherian, J | 1 |
| Zhao, Y | 1 |
| DeLaMora, P | 1 |
| Syverson, G | 1 |
| Nativ, S | 1 |
| Twilt, M | 1 |
| Michelow, IC | 1 |
| Stepanovskiy, Y | 1 |
| Thatayatikom, A | 1 |
| Harel, L | 1 |
| Akoghlanian, S | 1 |
| Tucker, L | 1 |
| Marques, MC | 1 |
| Srinivasalu, H | 1 |
| Propst, EJ | 1 |
| Licameli, GR | 1 |
| Dedeoglu, F | 1 |
| Lapidus, S | 1 |
| Lkhagvasuren, B | 1 |
| Oka, T | 1 |
| Kutsuna, S | 1 |
| Ohmagari, N | 1 |
| Tanizaki, R | 1 |
| Hagino, N | 1 |
| Nishikomori, R | 1 |
| Ujiie, M | 1 |
| Takeshita, N | 1 |
| Hayakawa, K | 1 |
| Kato, Y | 1 |
| Kanagawa, S | 1 |
| Feder, HM | 2 |
| Salazar, JC | 1 |
| Peridis, S | 1 |
| Pilgrim, G | 1 |
| Koudoumnakis, E | 1 |
| Athanasopoulos, I | 1 |
| Houlakis, M | 1 |
| Parpounas, K | 1 |
| Zhukovsky, DS | 1 |
| Thomas, RR | 1 |
| Quinn, MG | 1 |
| Schuler, B | 1 |
| Grem, JL | 1 |
| Pinto, A | 1 |
| Lindemeyer, RG | 1 |
| Sollecito, TP | 1 |
| Kolokotronis, A | 1 |
| Markopoulos, A | 1 |
| Voutas, S | 1 |
| Mataftsi, A | 1 |
| Ikonomidis, P | 1 |
| Antoniades, D | 1 |
| Schorderet, DF | 1 |
| Femiano, F | 1 |
| Lanza, A | 1 |
| Buonaiuto, C | 1 |
| Gombos, F | 1 |
| Cirillo, N | 1 |
| Landolfo, K | 1 |
| Low, DE | 1 |
| Rogers, AG | 1 |
| Hake, DH | 1 |
| Richter, JE | 1 |
| Gerhardt, DC | 1 |
| Pasquale, DN | 1 |
| Castell, DO | 1 |
| Chia, JK | 1 |
| Kim, DO | 1 |
| Lebow, RC | 1 |
| Pillet, P | 1 |
| Ansoborlo, S | 1 |
| Carrère, A | 1 |
| Perel, Y | 1 |
| Guillard, JM | 1 |
| Lee, WI | 1 |
| Yang, MH | 1 |
| Lee, KF | 1 |
| Chen, LC | 1 |
| Lin, SJ | 1 |
| Yeh, KW | 1 |
| Huang, JL | 1 |
| Ramboer, C | 1 |
| Nisticò, G | 1 |
| Rotiroti, D | 1 |
| de Sarro, A | 1 |
| Naccari, F | 1 |
| Corbett, CL | 1 |
| Holdsworth, CD | 1 |
| Steiner, A | 1 |
| Wolf, C | 1 |
| Pehamberger, H | 1 |
| Potter, HP | 1 |
| Byrne, EB | 1 |
| Lebovitz, S | 1 |
| Parenti, CM | 1 |
| Hoffman, JE | 1 |
| Fredlund, H | 1 |
| Holmberg, H | 1 |
6 reviews available for cimetidine and Fever
| Article | Year |
|---|---|
A clinical review of 105 patients with PFAPA (a periodic fever syndrome).
Topics: Child, Preschool; Cimetidine; Female; Fever; Histamine H2 Antagonists; Humans; Lymphadenitis; Male; | 2010 |
PFAPA syndrome in children: A meta-analysis on surgical versus medical treatment.
Topics: Adenoidectomy; Anti-Bacterial Agents; Child; Cimetidine; Fever; Glucocorticoids; Histamine H2 Antago | 2010 |
Fever and sweats in the patient with advanced cancer.
Topics: Analgesics, Non-Narcotic; Baths; Body Temperature; Causality; Cimetidine; Cryotherapy; Diagnosis, Di | 2002 |
Hypersensitivity and idiosyncratic reactions to oxaliplatin.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Antiemetics; Antineoplastic Agents; Cim | 2003 |
The PFAPA syndrome in oral medicine: differential diagnosis and treatment.
Topics: Analgesics; Anti-Inflammatory Agents; Child; Child, Preschool; Cimetidine; Diagnosis, Differential; | 2006 |
Oral aphthous-like lesions, PFAPA syndrome: a review.
Topics: Child; Cimetidine; Cytokines; Diagnosis, Differential; Fever; Histamine H2 Antagonists; Humans; Lymp | 2008 |
1 trial available for cimetidine and Fever
| Article | Year |
|---|---|
Colchicine versus cimetidine: the better choice for Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome prophylaxis, and the role of MEFV gene mutations.
Topics: Child; Cimetidine; Colchicine; Fever; Humans; Lymphadenitis; Lymphadenopathy; Mutation; Pharyngitis; | 2022 |
19 other studies available for cimetidine and Fever
| Article | Year |
|---|---|
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome: Clinical characteristics and treatment outcomes - a single center study in Japan.
Topics: Child; Cimetidine; Colchicine; Female; Fever; Humans; Infant, Newborn; Japan; Lymphadenitis; Lymphad | 2022 |
Consensus treatment plans for periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (PFAPA): a framework to evaluate treatment responses from the childhood arthritis and rheumatology research alliance (CARRA) PFAPA work group.
Topics: Adrenal Cortex Hormones; Advisory Committees; Antipyretics; Child; Child, Preschool; Cimetidine; Col | 2020 |
The histaminergic system is involved in psychological stress-induced hyperthermia in rats.
Topics: Animals; Body Temperature Regulation; Cimetidine; Fever; Histamine; Histamine Agonists; Imidazoles; | 2017 |
The first case of adult-onset PFAPA syndrome in Japan.
Topics: Adult; Cimetidine; Cytoskeletal Proteins; Female; Fever; Glucocorticoids; Heterozygote; Humans; Japa | 2016 |
Conjunctivitis as a sign of PFAPA syndrome.
Topics: Abdominal Pain; Child; Cimetidine; Conjunctivitis; Fever; Histamine H2 Antagonists; Humans; Lymphade | 2007 |
Cimetidine-induced fever.
Topics: Administration, Oral; Aged; Cimetidine; Duodenal Ulcer; Female; Fever; Humans | 1984 |
Interstitial nephritis and cimetidine.
Topics: Cimetidine; Fever; Guanidines; Humans; Male; Middle Aged; Nephritis, Interstitial; Recurrence | 1981 |
Cimetidine and hematologic suppression: things are not always as they appear.
Topics: Aged; Agranulocytosis; Blood Transfusion; Cimetidine; Duodenal Ulcer; Eosinophilia; Fever; Guanidine | 1980 |
Recurrent fever, leukocytosis, and abdominal pain due to treatment with cimetidine.
Topics: Abdominal Pain; Aged; Cimetidine; Fever; Humans; Leukocytosis; Male; Recurrence; Stomach Ulcer | 1994 |
[(P)FAPA syndrome: value of cimetidine].
Topics: Child; Child, Preschool; Cimetidine; Enzyme Inhibitors; Female; Fever; Humans; Infant; Lymphadenitis | 2000 |
PFAPA syndrome (Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis).
Topics: Azathioprine; Child; Cimetidine; Fever; Humans; Immunosuppressive Agents; Infant; Lymphadenitis; Mal | 1999 |
[Drug fever with cimetidine].
Topics: Aged; Cimetidine; Female; Fever; Guanidines; Humans; Male | 1978 |
Mechanism of cimetidine-induced fever.
Topics: Animals; Chickens; Cimetidine; Fever; Guanidines; Humans; Hypothalamus; Receptors, Histamine H2 | 1978 |
Fever, abdominal pain, and leucopenia during treatment with cimetidine.
Topics: Abdomen; Adult; Cimetidine; Female; Fever; Guanidines; Humans; Leukopenia; Pain; Transaminases | 1978 |
Cimetidine treatment for periodic fever associated with aphthous stomatitis, pharyngitis and cervical adenitis.
Topics: Adolescent; Child; Child, Preschool; Cimetidine; Fever; Humans; Lymphadenitis; Male; Periodicity; Ph | 1992 |
Comparison of the effects of three different treatment regimens of recombinant interferons (r-IFN alpha, r-IFN gamma, and r-IFN alpha + cimetidine) in disseminated malignant melanoma.
Topics: Cimetidine; Drug Evaluation; Drug Therapy, Combination; Fatigue; Female; Fever; Humans; Interferon T | 1987 |
Fever after cimetidine and ranitidine.
Topics: Cimetidine; Fever; Humans; Male; Middle Aged; Ranitidine | 1986 |
Hyperpyrexia associated with intravenous cimetidine therapy. Report of a case.
Topics: Cimetidine; Delirium; Duodenal Ulcer; Fever; Humans; Injections, Intravenous; Male; Middle Aged | 1986 |
[Fever in cimetidine-treated patients].
Topics: Aged; Cimetidine; Female; Fever; Humans | 1985 |