fentanyl and Fever

fentanyl has been researched along with Fever in 16 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research

Studies (16)

Authors

Clinical Trials (1)

Trial Overview

Trial Outcomes

Assessment Of Adherence Of The SSEC System To Skin

The adhesion of each SSEC was evaluated immediately prior to removal at each 24-hour time point, or at early withdrawal. Adhesion was recorded using the following classification: System adhered to at least 90% of the application area with no edges unattached; System adhered between 75% and 89%; System was <75% adhered and not taped; System was secured with tape. The number of SSEC systems for all time points in each category is presented. Because of the descriptive nature of this study, no formal statistical hypothesis testing was performed. (NCT02395653)
Timeframe: Immediately prior to removal at each 24-hour time point, or at early withdrawal, for up to 3 consecutive days (up to 72 hours)

Assessment Of Participant's Ability To Use The SSEC

Investigator's assessment of participant's ability to use the SSEC system safely and effectively. The assessment consisted of a 4-level categorical evaluation (poor, fair, good, and excellent). Because of the descriptive nature of this study, no formal statistical hypothesis testing was performed. (NCT02395653)
Timeframe: Completed at the time of the participant's termination of study treatment (up to 72 hours after study drug administration)

Change From Baseline To 1 Hour And 24 Hours In Skin Irritation Score After SSEC Removal

Skin irritation at the SSEC application site was to be assessed immediately prior to placement of the study system and at 1 and 24 hours after removal of each study system. The application site was to be scored using the following scale: 0=No evidence of irritation; 1=Minimal erythema, barely perceptible; 2=Definite erythema, readily visible, minimal edema, or minimal papular response; 3=Erythema and papules; 4=Definite edema; 5=Erythema, edema, and papules; 6=Vesicular eruption; 7=Strong reaction spreading beyond the application site. (NCT02395653)
Timeframe: Baseline, 1 hour and 24 hours after SSEC removal.

Number Of Participants To Experience Clinically Relevant Respiratory Depression (CRRD)

Respiratory function and occurrence of CRRD was defined as simultaneous occurrence of bradypnoea (respiratory rate <10 breaths per minute for participants 9-15 years of age and sustained for 1 minute, or <8 breaths per minute for participants 16-17 years of age), with excessive sedation (that is, the participant is not easily aroused). (NCT02395653)
Timeframe: From the time of application of the first system through 7 days following end of study drug administration.

Reviews

1 review available for fentanyl and Fever

Trials

1 trial available for fentanyl and Fever

Other Studies

14 other studies available for fentanyl and Fever