fentanyl has been researched along with Fever in 16 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
Excerpt | Relevance | Reference |
---|---|---|
"Although fentanyl patches (FP) designed to sustain plasma fentanyl concentrations for 3 days are used in many patients for continuous relief of moderate to severe cancer pain, there are some cases in which effective pain relief is sustained less than for 3 days, and in which plasma fentanyl concentrations rapidly decrease at the third day after the application." | 3.74 | [Measurement of amount of fentanyl remaining in used patches: investigation of clinical factors affecting the remaining amounts in 4 patients]. ( Iguchi, H; Kojima, M; Ohta, T; Yamamoto, K, 2008) |
"Fever was induced each day by 150 IU/g intravenous interleukin 2." | 2.70 | Opioids inhibit febrile responses in humans, whereas epidural analgesia does not: an explanation for hyperthermia during epidural analgesia. ( Bastanmehr, H; Bjorksten, AR; Ettinger, K; Lenhardt, R; Negishi, C; Ozaki, M; Sessler, DI, 2001) |
"Fentanyl ITS was equally effective when compared with morphine IV PCA for patient subpopulations (age, surgery type, and BMI)." | 2.44 | The safety and efficacy of fentanyl iontophoretic transdermal system compared with morphine intravenous patient-controlled analgesia for postoperative pain management: an analysis of pooled data from three randomized, active-controlled clinical studies. ( Damaraju, CV; Hewitt, DJ; Kershaw, P; Siccardi, M; Viscusi, ER, 2007) |
"Paroxysmal autonomic instability with dystonia (PAID) is an underdiagnosed syndrome that describes a collection of symptoms following diverse cerebral insults, such as traumatic brain injury, hydrocephalus, hemorrhagic stroke, or brain anoxia." | 1.56 | Transdermal opioid patch in treatment of paroxysmal autonomic instability with dystonia with multiple cerebral insults: A case report. ( Baik, SW; Kang, DH; Kim, GW, 2020) |
"Flurbiprofen axetil was used for slight postoperative fever." | 1.35 | [Perioperative anesthetic management of a patient with multiple sclerosis]. ( Hirose, M; Ishimoto, M; Matsuki, Y; Nobukawa, Y; Okada, A; Shigemi, K; Shimizu, K; Tabata, M; Tsugita, K; Ueda, M, 2009) |
"We present two cases of scorpion envenomation with different and rare clinical situations with a short review of the literature." | 1.35 | Unusual presentations of scorpion envenomation. ( Demir, M; Ranu Alpay, N; Satar, S; Sebe, A; Topal, M, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (12.50) | 18.7374 |
1990's | 1 (6.25) | 18.2507 |
2000's | 9 (56.25) | 29.6817 |
2010's | 1 (6.25) | 24.3611 |
2020's | 3 (18.75) | 2.80 |
Authors | Studies |
---|---|
Seiler, FA | 1 |
Scavone, BM | 1 |
Shahul, S | 1 |
Arnolds, DE | 1 |
Baik, SW | 1 |
Kang, DH | 1 |
Kim, GW | 1 |
Voruz, F | 1 |
Leuchter, I | 1 |
Savić Vujović, KR | 1 |
Vučković, S | 1 |
Srebro, D | 1 |
Ivanović, M | 1 |
Došen-Mićović, L | 1 |
Vučetić, Č | 1 |
Džoljić, E | 1 |
Prostran, M | 1 |
Yamamoto, K | 1 |
Kojima, M | 1 |
Iguchi, H | 1 |
Ohta, T | 1 |
Okada, A | 1 |
Hirose, M | 1 |
Shimizu, K | 1 |
Tsugita, K | 1 |
Matsuki, Y | 1 |
Nobukawa, Y | 1 |
Tabata, M | 1 |
Ishimoto, M | 1 |
Ueda, M | 1 |
Shigemi, K | 1 |
Brown, T | 1 |
Cao, WH | 1 |
Morrison, SF | 1 |
Phadke, A | 1 |
Broadman, LM | 1 |
Brandom, BW | 1 |
Ozolek, J | 1 |
Davis, PJ | 1 |
Viscusi, ER | 1 |
Siccardi, M | 1 |
Damaraju, CV | 1 |
Hewitt, DJ | 1 |
Kershaw, P | 1 |
Ranu Alpay, N | 1 |
Satar, S | 1 |
Sebe, A | 1 |
Demir, M | 1 |
Topal, M | 1 |
Lees, DE | 1 |
Kim, YD | 1 |
Bull, JM | 1 |
Whang-Peng, J | 1 |
Schuette, W | 1 |
Smith, R | 1 |
Macnamara, TE | 1 |
Leung, WK | 1 |
Jahr, JS | 1 |
Hotz, J | 1 |
Pollock, M | 1 |
Caulkett, NA | 1 |
Cribb, PH | 1 |
Haigh, JC | 1 |
Negishi, C | 1 |
Lenhardt, R | 1 |
Ozaki, M | 1 |
Ettinger, K | 1 |
Bastanmehr, H | 1 |
Bjorksten, AR | 1 |
Sessler, DI | 1 |
Fava, E | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
An Open Label Evaluation of the Safety and Clinical Utility of the Active, Separated System With Enhanced Controller (SSEC) Fentanyl 40 mcg for the Management of Acute Postoperative Pain in Pediatric Patients 12 to Less Than 18 Years of Age[NCT02395653] | Phase 3 | 71 participants (Actual) | Interventional | 2015-06-29 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The adhesion of each SSEC was evaluated immediately prior to removal at each 24-hour time point, or at early withdrawal. Adhesion was recorded using the following classification: System adhered to at least 90% of the application area with no edges unattached; System adhered between 75% and 89%; System was <75% adhered and not taped; System was secured with tape. The number of SSEC systems for all time points in each category is presented. Because of the descriptive nature of this study, no formal statistical hypothesis testing was performed. (NCT02395653)
Timeframe: Immediately prior to removal at each 24-hour time point, or at early withdrawal, for up to 3 consecutive days (up to 72 hours)
Intervention | SSEC systems (Number) | ||||
---|---|---|---|---|---|
≥90% of area with no edges unattached | 75% to 89% | <75% adhered and not taped | System was secured with tape | Not assessed | |
SSEC Fentanyl | 97 | 6 | 3 | 1 | 0 |
Investigator's assessment of participant's ability to use the SSEC system safely and effectively. The assessment consisted of a 4-level categorical evaluation (poor, fair, good, and excellent). Because of the descriptive nature of this study, no formal statistical hypothesis testing was performed. (NCT02395653)
Timeframe: Completed at the time of the participant's termination of study treatment (up to 72 hours after study drug administration)
Intervention | participants (Number) | ||||
---|---|---|---|---|---|
Poor | Fair | Good | Excellent | Missing | |
SSEC Fentanyl | 1 | 2 | 10 | 48 | 0 |
Skin irritation at the SSEC application site was to be assessed immediately prior to placement of the study system and at 1 and 24 hours after removal of each study system. The application site was to be scored using the following scale: 0=No evidence of irritation; 1=Minimal erythema, barely perceptible; 2=Definite erythema, readily visible, minimal edema, or minimal papular response; 3=Erythema and papules; 4=Definite edema; 5=Erythema, edema, and papules; 6=Vesicular eruption; 7=Strong reaction spreading beyond the application site. (NCT02395653)
Timeframe: Baseline, 1 hour and 24 hours after SSEC removal.
Intervention | units on a scale (Mean) | |||||
---|---|---|---|---|---|---|
System 1, Hour 1 | System 1, Hour 24 | System 2, Hour 1 | System 2, Hour 24 | System 3, Hour 1 | System 3, Hour 24 | |
SSEC Fentanyl | 1.1 | 1.8 | 1.0 | 1.6 | 1.0 | 0.8 |
Respiratory function and occurrence of CRRD was defined as simultaneous occurrence of bradypnoea (respiratory rate <10 breaths per minute for participants 9-15 years of age and sustained for 1 minute, or <8 breaths per minute for participants 16-17 years of age), with excessive sedation (that is, the participant is not easily aroused). (NCT02395653)
Timeframe: From the time of application of the first system through 7 days following end of study drug administration.
Intervention | participants (Number) | ||
---|---|---|---|
Bradypnoea | Excessive Sedation | Simultaneous Bradypnoea and Excessive Sedation | |
SSEC Fentanyl | 0 | 0 | 0 |
1 review available for fentanyl and Fever
Article | Year |
---|---|
The safety and efficacy of fentanyl iontophoretic transdermal system compared with morphine intravenous patient-controlled analgesia for postoperative pain management: an analysis of pooled data from three randomized, active-controlled clinical studies.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Female; Fentanyl; Fever; Humans; Iontophore | 2007 |
1 trial available for fentanyl and Fever
Article | Year |
---|---|
Opioids inhibit febrile responses in humans, whereas epidural analgesia does not: an explanation for hyperthermia during epidural analgesia.
Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Body Temperature; Cytokines; Fentanyl; Fever; Humans | 2001 |
14 other studies available for fentanyl and Fever
Article | Year |
---|---|
Maternal Fever Associated With Continuous Spinal Versus Epidural Labor Analgesia: A Single-Center Retrospective Study.
Topics: Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Bupivacaine; Female; Fentanyl; Feve | 2022 |
Transdermal opioid patch in treatment of paroxysmal autonomic instability with dystonia with multiple cerebral insults: A case report.
Topics: Analgesics, Opioid; Autonomic Nervous System Diseases; Basal Ganglia; Brain Ischemia; Diffusion Tens | 2020 |
Disseminated gonorrhea with laryngeal involvement in a 25-year-old man.
Topics: Administration, Intravenous; Adult; Anti-Bacterial Agents; Ceftriaxone; Exanthema; Fentanyl; Fever; | 2021 |
A comparison of the antinociceptive and temperature responses to morphine and fentanyl derivatives in rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Body Temperature; Disease Models, Animal; Dose-Respon | 2013 |
[Measurement of amount of fentanyl remaining in used patches: investigation of clinical factors affecting the remaining amounts in 4 patients].
Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Body Mass Index; Dosage Forms; Female; Fentanyl | 2008 |
[Perioperative anesthetic management of a patient with multiple sclerosis].
Topics: Adult; Anesthesia, Epidural; Fentanyl; Fever; Flurbiprofen; Humans; Infusions, Intravenous; Laparosc | 2009 |
Doctors and nurses, still learning.
Topics: Analgesics, Opioid; Clinical Competence; Communication; Fentanyl; Fever; Humans; Medical Staff, Hosp | 2009 |
Brown adipose tissue thermogenesis contributes to fentanyl-evoked hyperthermia.
Topics: Adipose Tissue, Brown; Animals; Cardiovascular System; Dorsomedial Hypothalamic Nucleus; Fentanyl; F | 2005 |
Postoperative hyperthermia, rhabdomyolysis, critical temperature, and death in a former premature infant after his ninth general anesthetic.
Topics: Analgesics, Opioid; Anesthesia, General; Fatal Outcome; Fentanyl; Fever; Humans; Infant; Infant, New | 2007 |
Unusual presentations of scorpion envenomation.
Topics: Adult; Analgesics, Opioid; Animals; Antivenins; Blood Cell Count; Blood Chemical Analysis; Echocardi | 2008 |
Anesthetic management of whole-body hyperthermia for the treatment of cancer.
Topics: Adolescent; Adult; Aged; Anesthetics; Body Temperature; Body Temperature Regulation; Chemical and Dr | 1980 |
Nonmalignant hyperthermia on induction of anesthesia in a pediatric patient undergoing bidirectional Glenn procedure.
Topics: Adjuvants, Anesthesia; Anastomosis, Surgical; Anesthesia, General; Anesthetics, Intravenous; Body Te | 1998 |
Comparative cardiopulmonary effects of carfentanil-xylazine and medetomidine-ketamine used for immobilization of mule deer and mule deer/white-tailed deer hybrids.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Dissociative; Animal Welfare; Animals; A | 2000 |
[Extra-operative anesthesiological importance of the drugs used in neuroleptoanalgesia].
Topics: Anesthesia; Anesthesia, Obstetrical; Benperidol; Fentanyl; Fever; Humans; Movement Disorders; Neurol | 1965 |