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ketoprofen and Fever

ketoprofen has been researched along with Fever in 24 studies

Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
"To compare three dose levels of ketoprofen with paracetamol (acetaminophen) in the management of fever in children."9.14Dose-finding studies of ketoprofen in the management of fever in children: report on two randomized, single-blind, comparator-controlled, single-dose, multicentre, phase II studies. ( Kokki, H; Kokki, M, 2010)
"This case report describes a previously healthy 35-year-old woman, with an episode of fever, neutropenia, thrombocytopenia and elevation of biochemical markers of liver injury, 10 days after beginning drug therapy with dexketoprofen trometamol."7.74Neutropenia, thrombocytopenia and hepatic injury associated with dexketoprofen trometamol therapy in a previously healthy 35-year-old woman. ( Calpe, MJ; Lerín, FJ; Mouronval, L; Pérez, G; Zabala, S, 2008)
"Fever is a common symptom in children and one of the major concerns of parents of younger and preschool-age children."6.75Ketoprofen versus paracetamol (acetaminophen) or ibuprofen in the management of fever: results of two randomized, double-blind, double-dummy, parallel-group, repeated-dose, multicentre, phase III studies in children. ( Kokki, H; Kokki, M, 2010)
"316 patients (6 months-12 years) with fever were randomly assigned to receive a single dose of acetaminophen or ketoprofen orally."5.16Comparison of acetaminophen and ketoprofen in febrile children: a single dose randomized clinical trial. ( Erkek, N; Karacan, CD; Senel, S, 2012)
"To compare three dose levels of ketoprofen with paracetamol (acetaminophen) in the management of fever in children."5.14Dose-finding studies of ketoprofen in the management of fever in children: report on two randomized, single-blind, comparator-controlled, single-dose, multicentre, phase II studies. ( Kokki, H; Kokki, M, 2010)
"In two multicentric randomized, double-blind, parallel design trials the more appropriate dose of ketoprofen lysine salt suppositories, by considering benefit-risk ratio, was determined in children affected by acute inflammatory disease of respiratory or urinary tract with fever and pain."5.08[Effects of various dosage of ketoprofen salt suppositories in acute inflammatory disease in infants (3-36 month old) and children (3-13 year old)]. ( Carnelli, VE; Cera, R; Clemente, E; Mei, VA; Previtali, M, 1995)
"The NSAID ketoprofen is used widely in the management of inflammatory and musculoskeletal conditions, pain, and fever in children and adults."4.86Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients. ( Kokki, H, 2010)
"This case report describes a previously healthy 35-year-old woman, with an episode of fever, neutropenia, thrombocytopenia and elevation of biochemical markers of liver injury, 10 days after beginning drug therapy with dexketoprofen trometamol."3.74Neutropenia, thrombocytopenia and hepatic injury associated with dexketoprofen trometamol therapy in a previously healthy 35-year-old woman. ( Calpe, MJ; Lerín, FJ; Mouronval, L; Pérez, G; Zabala, S, 2008)
"Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) orally effective in treating fever, pain, and inflammation but gastrointestinal side effects were observed."3.72Antipyretic, analgesic and anti-inflammatory activities of ketoprofen beta-cyclodextrin inclusion complexes in animals. ( Li, RY; Lu, WL; Shen, WB; Tu, XD; Wang, H; Zhang, LF; Zhang, Q; Zheng, L, 2004)
"Evidence for the effectiveness of ketoprofen in animal models of inflammation and its antipyretic effect is reviewed."3.65Some pharmacological and toxicological studies on ketoprofen. ( Ducrot, R; Guyonnet, JC; Julou, L; Pasquet, J, 1976)
"Fever is a common symptom in children and one of the major concerns of parents of younger and preschool-age children."2.75Ketoprofen versus paracetamol (acetaminophen) or ibuprofen in the management of fever: results of two randomized, double-blind, double-dummy, parallel-group, repeated-dose, multicentre, phase III studies in children. ( Kokki, H; Kokki, M, 2010)
"Fever was measured with the aid of a tympanic thermometer (Braun Kronberg 6014) and followed for 4-6 hours."2.74Antipyretic effect of ketoprofen. ( Akgoz, S; Arisoy, ES; Aygun, D; Celebi, S; Citak Kurt, AN; Hacimustafaoglu, M; Karali, Y; Seringec, M, 2009)
"Ketoprofen was a useful adjunct in the treatment of pyretic cats."2.68Use of ketoprofen as an antipyretic in cats. ( Aviad, AD; Glew, A; Keister, DM; Meo, NJ, 1996)
"Ketoprofen lysine salt (KLS) has a potent anti-inflammatory activity associated with effective analgesic and antipyretic effects and has a valuable safety profile."1.91Ketoprofen lysine salt treatment in adolescents with acute upper respiratory infections: a primary-care experience. ( Ciprandi, G; Marseglia, GL; Veraldi, D, 2023)
"We evaluated the modulatory role of the groundwater contaminant arsenic on the pharmacodynamic responses of the nonsteroidal analgesic-antipyretic drug ketoprofen and the major pro-inflammatory mediators linked to the mechanism of ketoprofen's therapeutic effects."1.38Subacute arsenic exposure through drinking water reduces the pharmacodynamic effects of ketoprofen in male rats. ( Ahmad, W; Chanderashekara, HH; Prawez, S; Sankar, P; Sarkar, SN; Tandan, SK, 2012)
"Dexketoprofen was the most effective antipyretic agent at the doses tested."1.38[Hemodynamic and antipyretic effects of paracetamol, metamizol and dexketoprofen in critical patients]. ( Betbesé, AJ; Gich, I; Mancebo, J; Vera, P; Zapata, L, 2012)
"Firocoxib is a potent COX-2 inhibitor and is the only selective COX-2 inhibitor described for use in cats to date."1.33In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in cats with lipopolysaccharide-induced pyrexia. ( Black, WC; Brideau, C; Cunningham, PK; Hickey, GJ; Hora, DF; McCann, ME; Rickes, EL; Zhang, D, 2005)
"S(+)-ketoprofen is a potent antiinflammatory, analgesic, and antipyretic agent in vivo, consistent with its potent anti-COX activity."1.30Analgesic, antiinflammatory, and antipyretic effects of S(+)-ketoprofen in vivo. ( Cabré, F; Calvo, L; Fernández, MF; Ferrer, X; García, ML; Mauleón, D, 1998)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.67)18.7374
1990's4 (16.67)18.2507
2000's6 (25.00)29.6817
2010's9 (37.50)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Marseglia, GL1
Veraldi, D1
Ciprandi, G1
Benelli, E1
Massaro, M1
Norbedo, S1
Carbone, M1
Barbi, E1
Ventura, A1
Celebi, S1
Hacimustafaoglu, M1
Aygun, D1
Arisoy, ES1
Karali, Y1
Akgoz, S1
Citak Kurt, AN1
Seringec, M1
Kokki, H3
Kokki, M2
Fosse, TK1
Toutain, PL1
Spadavecchia, C1
Haga, HA1
Horsberg, TE1
Ranheim, B1
Salichs, M1
Sabaté, D1
Ciervo, O1
Homedes, J1
Senel, S1
Erkek, N1
Karacan, CD1
Ahmad, W1
Prawez, S1
Chanderashekara, HH1
Tandan, SK1
Sankar, P1
Sarkar, SN1
Vera, P1
Zapata, L1
Gich, I1
Mancebo, J1
Betbesé, AJ1
Lu, WL1
Zhang, Q1
Zheng, L1
Wang, H1
Li, RY1
Zhang, LF1
Shen, WB1
Tu, XD1
McCann, ME1
Rickes, EL1
Hora, DF1
Cunningham, PK1
Zhang, D1
Brideau, C1
Black, WC1
Hickey, GJ1
Deligne, J1
Grimaldi, L1
Jonville-Béra, AP1
Giraudeau, B1
Blum-Boisgard, C1
Autret-Leca, E1
Zabala, S1
Calpe, MJ1
Pérez, G1
Lerín, FJ1
Mouronval, L1
Keinänen-Kiukaanniemi, S1
Similä, S1
Kouvalainen, K1
Carnelli, VE1
Mei, VA1
Cera, R1
Clemente, E1
Previtali, M1
Glew, A1
Aviad, AD1
Keister, DM1
Meo, NJ1
Kido, H1
Murakami, N1
Ito, A1
Kimura, K1
Kodera, N1
Doi, T1
Naruse, T1
Cabré, F1
Fernández, MF1
Calvo, L1
Ferrer, X1
García, ML1
Mauleón, D1
Davidson, J2
Abul, HT2
Milton, AS2
Rotondo, D2
Julou, L1
Guyonnet, JC1
Ducrot, R1
Pasquet, J1
Cremades, A1
Garcia-Peñarrubia, P1
Garcia, F1
Sánchez Rincón, I1

Reviews

1 review available for ketoprofen and Fever

ArticleYear
Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients.
    Paediatric drugs, 2010, Oct-01, Volume: 12, Issue:5

    Topics: Child; Fever; Humans; Inflammation; Ketoprofen; Perioperative Period

2010

Trials

8 trials available for ketoprofen and Fever

ArticleYear
Antipyretic effect of ketoprofen.
    Indian journal of pediatrics, 2009, Volume: 76, Issue:3

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents,

2009
Dose-finding studies of ketoprofen in the management of fever in children: report on two randomized, single-blind, comparator-controlled, single-dose, multicentre, phase II studies.
    Clinical drug investigation, 2010, Volume: 30, Issue:4

    Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anti-Inflammatory Agents

2010
Ketoprofen versus paracetamol (acetaminophen) or ibuprofen in the management of fever: results of two randomized, double-blind, double-dummy, parallel-group, repeated-dose, multicentre, phase III studies in children.
    Clinical drug investigation, 2010, Volume: 30, Issue:6

    Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2010
Ketoprofen in piglets: enantioselective pharmacokinetics, pharmacodynamics and PK/PD modelling.
    Journal of veterinary pharmacology and therapeutics, 2011, Volume: 34, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Female; Fever; Inflammation; Kao

2011
Comparison of the antipyretic efficacy of ketoprofen, acetylsalicylic acid, and paracetamol, orally administered to swine.
    Journal of veterinary pharmacology and therapeutics, 2012, Volume: 35, Issue:2

    Topics: Acetaminophen; Administration, Oral; Animals; Antipyretics; Aspirin; Fever; Ketoprofen; Lipopolysacc

2012
Comparison of acetaminophen and ketoprofen in febrile children: a single dose randomized clinical trial.
    Indian journal of pediatrics, 2012, Volume: 79, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Child; Child, Preschool; Femal

2012
[Effects of various dosage of ketoprofen salt suppositories in acute inflammatory disease in infants (3-36 month old) and children (3-13 year old)].
    Minerva pediatrica, 1995, Volume: 47, Issue:5

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents; Body Temperature; Child; Child, Preschool; Dose

1995
Use of ketoprofen as an antipyretic in cats.
    The Canadian veterinary journal = La revue veterinaire canadienne, 1996, Volume: 37, Issue:4

    Topics: Amoxicillin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cat Diseases; Cats;

1996

Other Studies

15 other studies available for ketoprofen and Fever

ArticleYear
Ketoprofen lysine salt treatment in adolescents with acute upper respiratory infections: a primary-care experience.
    Minerva pediatrics, 2023, Volume: 75, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Female; Fever; Humans; Ketoprofen; Male; Respir

2023
An unusual cause of torticollis.
    The Journal of pediatrics, 2013, Volume: 163, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Atlanto-Axial Joint; Child, Preschool; Diazepam; Female; Fe

2013
Subacute arsenic exposure through drinking water reduces the pharmacodynamic effects of ketoprofen in male rats.
    Environmental toxicology and pharmacology, 2012, Volume: 33, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arsenites; Carrageenan; Cycl

2012
[Hemodynamic and antipyretic effects of paracetamol, metamizol and dexketoprofen in critical patients].
    Medicina intensiva, 2012, Volume: 36, Issue:9

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics

2012
Antipyretic, analgesic and anti-inflammatory activities of ketoprofen beta-cyclodextrin inclusion complexes in animals.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:10

    Topics: Adjuvants, Pharmaceutic; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal;

2004
In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in cats with lipopolysaccharide-induced pyrexia.
    American journal of veterinary research, 2005, Volume: 66, Issue:7

    Topics: 4-Butyrolactone; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cat Disease

2005
Antipyretic drug use in children in French office based medical practice.
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:7

    Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Aspirin; Child; Child, Preschool; Drug Therapy

2007
Neutropenia, thrombocytopenia and hepatic injury associated with dexketoprofen trometamol therapy in a previously healthy 35-year-old woman.
    Journal of clinical pharmacy and therapeutics, 2008, Volume: 33, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Fever; Humans; Ketoprofen; Liver; Liver Func

2008
Oral antipyretic therapy evaluation of the propionic acid derivatives ibuprofen, ketoprofen, fenoprofen and naproxen.
    Padiatrie und Padologie, 1980, Volume: 15, Issue:3

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Fen

1980
Anti-inflammatory, analgesic and anti-pyretic effects of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a new non-steroidal anti-inflammatory drug, in rats and guinea pigs.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1998
Analgesic, antiinflammatory, and antipyretic effects of S(+)-ketoprofen in vivo.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:S1

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ca

1998
Cytokines and cytokine inducers stimulate prostaglandin E2 entry into the brain.
    Pflugers Archiv : European journal of physiology, 2001, Volume: 442, Issue:4

    Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Brain;

2001
Some pharmacological and toxicological studies on ketoprofen.
    Rheumatology and rehabilitation, 1976, Volume: Suppl

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Fever; Guinea Pigs; Indometha

1976
Pyrogenic immunomodulators increase the level of prostaglandin E2 in the blood simultaneously with the onset of fever.
    European journal of pharmacology, 1988, Sep-13, Volume: 154, Issue:2

    Topics: Animals; Body Temperature; Dinoprostone; Fever; Interleukin-1; Ketoprofen; Lipopolysaccharides; Male

1988
Effect of different treatments of the endotoxin-induced modifications in serum iron levels.
    General pharmacology, 1986, Volume: 17, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Endotoxins; Female; Fever; Indomethacin; Iron; Ket

1986