ketoprofen and Fever
ketoprofen has been researched along with Fever in 24 studies
Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare three dose levels of ketoprofen with paracetamol (acetaminophen) in the management of fever in children." | 9.14 | Dose-finding studies of ketoprofen in the management of fever in children: report on two randomized, single-blind, comparator-controlled, single-dose, multicentre, phase II studies. ( Kokki, H; Kokki, M, 2010) |
| "This case report describes a previously healthy 35-year-old woman, with an episode of fever, neutropenia, thrombocytopenia and elevation of biochemical markers of liver injury, 10 days after beginning drug therapy with dexketoprofen trometamol." | 7.74 | Neutropenia, thrombocytopenia and hepatic injury associated with dexketoprofen trometamol therapy in a previously healthy 35-year-old woman. ( Calpe, MJ; Lerín, FJ; Mouronval, L; Pérez, G; Zabala, S, 2008) |
| "Fever is a common symptom in children and one of the major concerns of parents of younger and preschool-age children." | 6.75 | Ketoprofen versus paracetamol (acetaminophen) or ibuprofen in the management of fever: results of two randomized, double-blind, double-dummy, parallel-group, repeated-dose, multicentre, phase III studies in children. ( Kokki, H; Kokki, M, 2010) |
| "316 patients (6 months-12 years) with fever were randomly assigned to receive a single dose of acetaminophen or ketoprofen orally." | 5.16 | Comparison of acetaminophen and ketoprofen in febrile children: a single dose randomized clinical trial. ( Erkek, N; Karacan, CD; Senel, S, 2012) |
| "To compare three dose levels of ketoprofen with paracetamol (acetaminophen) in the management of fever in children." | 5.14 | Dose-finding studies of ketoprofen in the management of fever in children: report on two randomized, single-blind, comparator-controlled, single-dose, multicentre, phase II studies. ( Kokki, H; Kokki, M, 2010) |
| "In two multicentric randomized, double-blind, parallel design trials the more appropriate dose of ketoprofen lysine salt suppositories, by considering benefit-risk ratio, was determined in children affected by acute inflammatory disease of respiratory or urinary tract with fever and pain." | 5.08 | [Effects of various dosage of ketoprofen salt suppositories in acute inflammatory disease in infants (3-36 month old) and children (3-13 year old)]. ( Carnelli, VE; Cera, R; Clemente, E; Mei, VA; Previtali, M, 1995) |
| "The NSAID ketoprofen is used widely in the management of inflammatory and musculoskeletal conditions, pain, and fever in children and adults." | 4.86 | Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients. ( Kokki, H, 2010) |
| "This case report describes a previously healthy 35-year-old woman, with an episode of fever, neutropenia, thrombocytopenia and elevation of biochemical markers of liver injury, 10 days after beginning drug therapy with dexketoprofen trometamol." | 3.74 | Neutropenia, thrombocytopenia and hepatic injury associated with dexketoprofen trometamol therapy in a previously healthy 35-year-old woman. ( Calpe, MJ; Lerín, FJ; Mouronval, L; Pérez, G; Zabala, S, 2008) |
| "Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) orally effective in treating fever, pain, and inflammation but gastrointestinal side effects were observed." | 3.72 | Antipyretic, analgesic and anti-inflammatory activities of ketoprofen beta-cyclodextrin inclusion complexes in animals. ( Li, RY; Lu, WL; Shen, WB; Tu, XD; Wang, H; Zhang, LF; Zhang, Q; Zheng, L, 2004) |
| "Evidence for the effectiveness of ketoprofen in animal models of inflammation and its antipyretic effect is reviewed." | 3.65 | Some pharmacological and toxicological studies on ketoprofen. ( Ducrot, R; Guyonnet, JC; Julou, L; Pasquet, J, 1976) |
| "Fever is a common symptom in children and one of the major concerns of parents of younger and preschool-age children." | 2.75 | Ketoprofen versus paracetamol (acetaminophen) or ibuprofen in the management of fever: results of two randomized, double-blind, double-dummy, parallel-group, repeated-dose, multicentre, phase III studies in children. ( Kokki, H; Kokki, M, 2010) |
| "Fever was measured with the aid of a tympanic thermometer (Braun Kronberg 6014) and followed for 4-6 hours." | 2.74 | Antipyretic effect of ketoprofen. ( Akgoz, S; Arisoy, ES; Aygun, D; Celebi, S; Citak Kurt, AN; Hacimustafaoglu, M; Karali, Y; Seringec, M, 2009) |
| "Ketoprofen was a useful adjunct in the treatment of pyretic cats." | 2.68 | Use of ketoprofen as an antipyretic in cats. ( Aviad, AD; Glew, A; Keister, DM; Meo, NJ, 1996) |
| "Ketoprofen lysine salt (KLS) has a potent anti-inflammatory activity associated with effective analgesic and antipyretic effects and has a valuable safety profile." | 1.91 | Ketoprofen lysine salt treatment in adolescents with acute upper respiratory infections: a primary-care experience. ( Ciprandi, G; Marseglia, GL; Veraldi, D, 2023) |
| "We evaluated the modulatory role of the groundwater contaminant arsenic on the pharmacodynamic responses of the nonsteroidal analgesic-antipyretic drug ketoprofen and the major pro-inflammatory mediators linked to the mechanism of ketoprofen's therapeutic effects." | 1.38 | Subacute arsenic exposure through drinking water reduces the pharmacodynamic effects of ketoprofen in male rats. ( Ahmad, W; Chanderashekara, HH; Prawez, S; Sankar, P; Sarkar, SN; Tandan, SK, 2012) |
| "Dexketoprofen was the most effective antipyretic agent at the doses tested." | 1.38 | [Hemodynamic and antipyretic effects of paracetamol, metamizol and dexketoprofen in critical patients]. ( Betbesé, AJ; Gich, I; Mancebo, J; Vera, P; Zapata, L, 2012) |
| "Firocoxib is a potent COX-2 inhibitor and is the only selective COX-2 inhibitor described for use in cats to date." | 1.33 | In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in cats with lipopolysaccharide-induced pyrexia. ( Black, WC; Brideau, C; Cunningham, PK; Hickey, GJ; Hora, DF; McCann, ME; Rickes, EL; Zhang, D, 2005) |
| "S(+)-ketoprofen is a potent antiinflammatory, analgesic, and antipyretic agent in vivo, consistent with its potent anti-COX activity." | 1.30 | Analgesic, antiinflammatory, and antipyretic effects of S(+)-ketoprofen in vivo. ( Cabré, F; Calvo, L; Fernández, MF; Ferrer, X; García, ML; Mauleón, D, 1998) |
Research
Studies (24)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (16.67) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 9 (37.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Marseglia, GL | 1 |
| Veraldi, D | 1 |
| Ciprandi, G | 1 |
| Benelli, E | 1 |
| Massaro, M | 1 |
| Norbedo, S | 1 |
| Carbone, M | 1 |
| Barbi, E | 1 |
| Ventura, A | 1 |
| Celebi, S | 1 |
| Hacimustafaoglu, M | 1 |
| Aygun, D | 1 |
| Arisoy, ES | 1 |
| Karali, Y | 1 |
| Akgoz, S | 1 |
| Citak Kurt, AN | 1 |
| Seringec, M | 1 |
| Kokki, H | 3 |
| Kokki, M | 2 |
| Fosse, TK | 1 |
| Toutain, PL | 1 |
| Spadavecchia, C | 1 |
| Haga, HA | 1 |
| Horsberg, TE | 1 |
| Ranheim, B | 1 |
| Salichs, M | 1 |
| Sabaté, D | 1 |
| Ciervo, O | 1 |
| Homedes, J | 1 |
| Senel, S | 1 |
| Erkek, N | 1 |
| Karacan, CD | 1 |
| Ahmad, W | 1 |
| Prawez, S | 1 |
| Chanderashekara, HH | 1 |
| Tandan, SK | 1 |
| Sankar, P | 1 |
| Sarkar, SN | 1 |
| Vera, P | 1 |
| Zapata, L | 1 |
| Gich, I | 1 |
| Mancebo, J | 1 |
| Betbesé, AJ | 1 |
| Lu, WL | 1 |
| Zhang, Q | 1 |
| Zheng, L | 1 |
| Wang, H | 1 |
| Li, RY | 1 |
| Zhang, LF | 1 |
| Shen, WB | 1 |
| Tu, XD | 1 |
| McCann, ME | 1 |
| Rickes, EL | 1 |
| Hora, DF | 1 |
| Cunningham, PK | 1 |
| Zhang, D | 1 |
| Brideau, C | 1 |
| Black, WC | 1 |
| Hickey, GJ | 1 |
| Deligne, J | 1 |
| Grimaldi, L | 1 |
| Jonville-Béra, AP | 1 |
| Giraudeau, B | 1 |
| Blum-Boisgard, C | 1 |
| Autret-Leca, E | 1 |
| Zabala, S | 1 |
| Calpe, MJ | 1 |
| Pérez, G | 1 |
| Lerín, FJ | 1 |
| Mouronval, L | 1 |
| Keinänen-Kiukaanniemi, S | 1 |
| Similä, S | 1 |
| Kouvalainen, K | 1 |
| Carnelli, VE | 1 |
| Mei, VA | 1 |
| Cera, R | 1 |
| Clemente, E | 1 |
| Previtali, M | 1 |
| Glew, A | 1 |
| Aviad, AD | 1 |
| Keister, DM | 1 |
| Meo, NJ | 1 |
| Kido, H | 1 |
| Murakami, N | 1 |
| Ito, A | 1 |
| Kimura, K | 1 |
| Kodera, N | 1 |
| Doi, T | 1 |
| Naruse, T | 1 |
| Cabré, F | 1 |
| Fernández, MF | 1 |
| Calvo, L | 1 |
| Ferrer, X | 1 |
| García, ML | 1 |
| Mauleón, D | 1 |
| Davidson, J | 2 |
| Abul, HT | 2 |
| Milton, AS | 2 |
| Rotondo, D | 2 |
| Julou, L | 1 |
| Guyonnet, JC | 1 |
| Ducrot, R | 1 |
| Pasquet, J | 1 |
| Cremades, A | 1 |
| Garcia-Peñarrubia, P | 1 |
| Garcia, F | 1 |
| Sánchez Rincón, I | 1 |
Reviews
1 review available for ketoprofen and Fever
| Article | Year |
|---|---|
Ketoprofen pharmacokinetics, efficacy, and tolerability in pediatric patients.
Topics: Child; Fever; Humans; Inflammation; Ketoprofen; Perioperative Period | 2010 |
Trials
8 trials available for ketoprofen and Fever
| Article | Year |
|---|---|
Antipyretic effect of ketoprofen.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, | 2009 |
Dose-finding studies of ketoprofen in the management of fever in children: report on two randomized, single-blind, comparator-controlled, single-dose, multicentre, phase II studies.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anti-Inflammatory Agents | 2010 |
Ketoprofen versus paracetamol (acetaminophen) or ibuprofen in the management of fever: results of two randomized, double-blind, double-dummy, parallel-group, repeated-dose, multicentre, phase III studies in children.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2010 |
Ketoprofen in piglets: enantioselective pharmacokinetics, pharmacodynamics and PK/PD modelling.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Female; Fever; Inflammation; Kao | 2011 |
Comparison of the antipyretic efficacy of ketoprofen, acetylsalicylic acid, and paracetamol, orally administered to swine.
Topics: Acetaminophen; Administration, Oral; Animals; Antipyretics; Aspirin; Fever; Ketoprofen; Lipopolysacc | 2012 |
Comparison of acetaminophen and ketoprofen in febrile children: a single dose randomized clinical trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Child; Child, Preschool; Femal | 2012 |
[Effects of various dosage of ketoprofen salt suppositories in acute inflammatory disease in infants (3-36 month old) and children (3-13 year old)].
Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents; Body Temperature; Child; Child, Preschool; Dose | 1995 |
Use of ketoprofen as an antipyretic in cats.
Topics: Amoxicillin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cat Diseases; Cats; | 1996 |
Other Studies
15 other studies available for ketoprofen and Fever
| Article | Year |
|---|---|
Ketoprofen lysine salt treatment in adolescents with acute upper respiratory infections: a primary-care experience.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Female; Fever; Humans; Ketoprofen; Male; Respir | 2023 |
An unusual cause of torticollis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Atlanto-Axial Joint; Child, Preschool; Diazepam; Female; Fe | 2013 |
Subacute arsenic exposure through drinking water reduces the pharmacodynamic effects of ketoprofen in male rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arsenites; Carrageenan; Cycl | 2012 |
[Hemodynamic and antipyretic effects of paracetamol, metamizol and dexketoprofen in critical patients].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics | 2012 |
Antipyretic, analgesic and anti-inflammatory activities of ketoprofen beta-cyclodextrin inclusion complexes in animals.
Topics: Adjuvants, Pharmaceutic; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2004 |
In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in cats with lipopolysaccharide-induced pyrexia.
Topics: 4-Butyrolactone; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cat Disease | 2005 |
Antipyretic drug use in children in French office based medical practice.
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Aspirin; Child; Child, Preschool; Drug Therapy | 2007 |
Neutropenia, thrombocytopenia and hepatic injury associated with dexketoprofen trometamol therapy in a previously healthy 35-year-old woman.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Fever; Humans; Ketoprofen; Liver; Liver Func | 2008 |
Oral antipyretic therapy evaluation of the propionic acid derivatives ibuprofen, ketoprofen, fenoprofen and naproxen.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Fen | 1980 |
Anti-inflammatory, analgesic and anti-pyretic effects of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a new non-steroidal anti-inflammatory drug, in rats and guinea pigs.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 1998 |
Analgesic, antiinflammatory, and antipyretic effects of S(+)-ketoprofen in vivo.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ca | 1998 |
Cytokines and cytokine inducers stimulate prostaglandin E2 entry into the brain.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Brain; | 2001 |
Some pharmacological and toxicological studies on ketoprofen.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Fever; Guinea Pigs; Indometha | 1976 |
Pyrogenic immunomodulators increase the level of prostaglandin E2 in the blood simultaneously with the onset of fever.
Topics: Animals; Body Temperature; Dinoprostone; Fever; Interleukin-1; Ketoprofen; Lipopolysaccharides; Male | 1988 |
Effect of different treatments of the endotoxin-induced modifications in serum iron levels.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Endotoxins; Female; Fever; Indomethacin; Iron; Ket | 1986 |