Page last updated: 2024-10-29

imipramine and Fever

imipramine has been researched along with Fever in 26 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
" Maternal exposure to imipramine in a dose equivalent to the therapeutic dose per unit body weight induced hyperthermic response to chlorpromazine in the male offspring, while normal control rats showed a marked hypothermia."3.69Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring. ( Fujii, T, 1997)
"Two schedules of imipramine (IM) administration were compared, a single intraperitoneal dose (10 mg/kg) (I) and chronic oral dosage (10 mg/kg twice a day for 14 days) (II)."1.26Different pharmacokinetic and pharmacological effects following acute and chronic treatment with imipramine. ( Daniel, W; Maj, J; Melzacka, M; Mogilnicka, E, 1982)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199023 (88.46)18.7374
1990's1 (3.85)18.2507
2000's2 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LEHMANN, HE1
THUILLIER, J1
NAKAJIMA, H1
GRANDJEAN, JL1
KURIHARA, M2
STREET, HV1
STANLEY, B1
PAL, NR1
DANDIYA, PC1
MENON, MK1
LOCKETT, MF1
MILNER, G1
HILLS, NF1
MORPURGO, C1
THEOBALD, W1
Müller, WE1
Siebert, B1
Holoubek, G1
Gentsch, C1
Liu, X1
Stancliffe, D1
Lee, S1
Mathur, S1
Gershenfeld, HK1
Graham, PM1
Potter, JM1
Paterson, J1
Maj, J1
Melzacka, M1
Mogilnicka, E1
Daniel, W1
Fujii, T1
Peebles-Brown, AE1
Loew, D1
Taeschler, M1
Gong, SN1
Rogers, KJ2
Gong, NC1
Jori, A1
Paglialunga, S1
Garattini, S1
Dixit, KS2
Dhasmana, KM2
Sinha, JN2
Bhargava, KP2
Suchowsky, GK1
Pegrassi, L1
Breese, GR1
Traylor, TD1
Prange, AJ1
Delini-Stula, A1
Saxene, RC1
Bhalla, TN1
Schuckit, M1
Robins, E1
Feighner, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Whole-Body Hyperthermia for Mood and Anxiety Disorders[NCT06144294]240 participants (Anticipated)Interventional2024-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

26 other studies available for imipramine and Fever

ArticleYear
Combined pharmaco-fever treatment with imipramine (tofranil) and typhoid vaccine in the management of depressive conditions.
    The American journal of psychiatry, 1960, Volume: 117

    Topics: Combined Modality Therapy; Depression; Depressive Disorder; Fever; Hyperthermia, Induced; Imipramine

1960
[Duality of action of imipramine on the hyperthermia induced by LSD-25 in the rabbit].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1962, Volume: 156

    Topics: Animals; Fever; Imipramine; Lysergic Acid Diethylamide; Rabbits

1962
The rapid separation of drugs and poisons by high temperature reversed phase paper chromatography. 2. Phenothiazine tranquilizers and imipramine.
    Acta pharmacologica et toxicologica, 1962, Volume: 19

    Topics: Chromatography, Paper; Chromatography, Reverse-Phase; Fever; Imipramine; Phenothiazines; Poisons; Ra

1962
[SOME PHARMACOLOGICAL EXPERIMENTS ON ANTIDEPRESSANTS--IN REFERENCE TO CEREBRAL MONOAMINES].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1963, Volume: 65

    Topics: 5-Hydroxytryptophan; Antidepressive Agents; Bemegride; Dihydroxyphenylalanine; Eyelids; Fever; Imipr

1963
FATAL HYPERPYREXIA WITH PHENELZINE AND IMIPRAMINE.
    British medical journal, 1964, Oct-17, Volume: 2, Issue:5415

    Topics: Alcoholism; Fever; Imipramine; Mental Disorders; Phenelzine; Poisoning; Toxicology

1964
ACTIONS OF ASARONE ON BEHAVIOR, STRESS, AND HYPERPYREXIA, AND ITS INTERACTION WITH CENTRAL STIMULANTS.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 145

    Topics: Allylbenzene Derivatives; Amphetamine; Amphetamines; Animals; Anisoles; Behavior, Animal; Central Ne

1964
COMBINING ANTIDEPRESSANT DRUGS.
    British medical journal, 1965, Apr-03, Volume: 1, Issue:5439

    Topics: Antidepressive Agents; Coma; Drug Therapy; Fever; Imipramine; Phenelzine; Toxicology

1965
COMBINING THE ANTIDEPRESSANT DRUGS.
    British medical journal, 1965, Mar-27, Volume: 1, Issue:5438

    Topics: Anorexia Nervosa; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Fever; Heada

1965
INFLUENCE OF IMPIRAMINE-LIKE COMPOUNDS AND CHLORPROMAZINE ON THE RESERPINE-HYPOTHERMIA IN MICE AND THE AMPHETAMINE-HYPERTHERMIA IN RATS.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1965, Volume: 12

    Topics: Amphetamine; Amphetamines; Animals; Chlorpromazine; Fever; Hypothermia; Hypothermia, Induced; Imipra

1965
Neuropharmacology of the anxiolytic drug opipramol, a sigma site ligand.
    Pharmacopsychiatry, 2004, Volume: 37 Suppl 3

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Dose-Response

2004
Genetic dissection of the tail suspension test: a mouse model of stress vulnerability and antidepressant response.
    Biological psychiatry, 2007, Jul-01, Volume: 62, Issue:1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Chromosome Mapping; Chromosomes, Mammalian; Crosse

2007
Combination monoamine oxidase inhibitor/tricyclic antidepressants interaction.
    Lancet (London, England), 1982, Aug-21, Volume: 2, Issue:8295

    Topics: Adolescent; Anorexia Nervosa; Cognition Disorders; Confusion; Drug Interactions; Female; Fever; Huma

1982
Different pharmacokinetic and pharmacological effects following acute and chronic treatment with imipramine.
    Journal of neural transmission, 1982, Volume: 54, Issue:3-4

    Topics: Animals; Brain Chemistry; Desipramine; Fenfluramine; Fever; Imipramine; Male; Norepinephrine; Rats;

1982
Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring.
    Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

    Topics: Aggression; Aminobutyrates; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplast

1997
Hyperpyrexia following psychotropic drug overdose.
    Anaesthesia, 1985, Volume: 40, Issue:11

    Topics: Adult; Drug Interactions; Female; Fever; Humans; Imipramine; Tranylcypromine

1985
[The effect of tricyclic antidepressants on rabbit 5-hydroxytryptophan hyperthermia].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1966, Volume: 252, Issue:5

    Topics: Animals; Antidepressive Agents; Desipramine; Fever; Imipramine; Nortriptyline; Rabbits; Serotonin; T

1966
Role of brain monoamines in the fatal hyperthermia induced by pethidine or imipramine in rabbits pretreated with pargyline.
    British journal of pharmacology, 1971, Volume: 42, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Catecholamines; Fenclonine; Fever; Imipramine; Injections, Intraven

1971
Mechanism of hyperthermia in the interaction between pethidine or imipramine and monoamine oxidase inhibitors.
    The Medical journal of Malaysia, 1973, Volume: 27, Issue:4

    Topics: Animals; Body Temperature Regulation; Drug Interactions; Fever; Humans; Imipramine; Male; Meperidine

1973
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpro

1967
Role of catecholamines in fatal hyperpyrexia induced by imipramine in MAOI treated rabbits.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 188, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Chlorisondamine; Chlorpromazine; Drug Antagoni

1970
The pharmacology of 4H-3-methylcarboxyamide-1,3-benzoxazine-2-one (F.I. 6654), a compound acting on the central nervous system.
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:4

    Topics: Anesthesia; Animals; Atropine; Barbiturates; Behavior, Animal; Cats; Central Nervous System; Depress

1969
The effect of triiodothyronine on the disposition and actions of imipramine.
    Psychopharmacologia, 1972, Volume: 25, Issue:2

    Topics: Adrenal Glands; Animals; Brain; Brain Chemistry; Carbon Isotopes; Dihydroxyphenylalanine; Drug Syner

1972
Drug-induced suppression of conditioned hyperthermic and conditioned avoidance behavior response in rats.
    Psychopharmacologia, 1971, Volume: 20, Issue:2

    Topics: Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Conditioning, Psychological; Fever; I

1971
Antipyretic effect of glycyrrhetic acid and imipramine.
    Japanese journal of pharmacology, 1968, Volume: 18, Issue:3

    Topics: Analgesics; Animals; Body Temperature; Fever; Imipramine; Rats; Saponins; Thermometers; Time Factors

1968
Antagonism of imipramine induced fatal hyperpyrexia in MAO inhibitor treated rabbits.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:4

    Topics: Amino Alcohols; Animals; Body Temperature; Drug Antagonism; Female; Fever; Imipramine; Male; Monoami

1969
Tricyclic antidepressants and monoamine oxidase inhibitors.
    Archives of general psychiatry, 1971, Volume: 24, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug

1971