Page last updated: 2024-10-30

lamotrigine and Fever

lamotrigine has been researched along with Fever in 16 studies

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this case series is to characterize a recently identified association of the antiepileptic drug (AED) lamotrigine with aseptic meningitis based on cases reported to the Food and Drug Administration (FDA)'s Adverse Event Reporting System (AERS) database."7.78Lamotrigine and aseptic meningitis. ( Avigan, M; Kortepeter, C; Simms, KM, 2012)
"The purpose of this case series is to characterize a recently identified association of the antiepileptic drug (AED) lamotrigine with aseptic meningitis based on cases reported to the Food and Drug Administration (FDA)'s Adverse Event Reporting System (AERS) database."3.78Lamotrigine and aseptic meningitis. ( Avigan, M; Kortepeter, C; Simms, KM, 2012)
" All had dermatological manifestations, eosinophilia and systemic (haematological and hepatic) manifestations that could be attributed to treatment with aromatic AEDs (carbamazepine, 2 patients; lamotrigine, 3 patients; phenytoin, 3 patients)."3.77Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs. ( Kochen, S; Pereira de Silva, N; Piquioni, P; Saidon, P, 2011)
"We describe an 11-year-old girl with a seizure disorder who developed fever, rash, rhabdomyolysis, and multiorgan failure 2 weeks after commencing a transition from sodium valproate to lamotrigine therapy."3.75Life-threatening organ failure after lamotrigine therapy. ( Dargan, PI; Ferguson, LP; Hood, JL; Tibby, SM, 2009)
" We present a 12 years old female who was a known case of idiopathic generalized tonic-clonic convulsion and presented with fever, diarrhea and generalized erythematous eruption after 2 weeks of being under treatment with maintenance doses of Lamotrigine (LTG) and Valproate (VPA)."3.74Intravenous immunoglobulin in the treatment of lamotrigine- induced toxic epidermal necrolysis. ( Inaloo, S; Serati Shirazi, Z, 2008)
"This report describes the laboratory and physical manifestations of lamotrigine-like toxicity in a young man with refractory epilepsy receiving lamotrigine presenting as anticonvulsant hypersensitivity syndrome (AHS) associated with an abrupt change of drug product."3.74Progressive anticonvulsant hypersensitivity syndrome associated with change of drug product. ( Sabers, A; Sabroe, TP, 2008)
"When lamotrigine was restarted 2 weeks later she developed similar but more severe symptoms which resolved on stopping lamotrigine."1.35Anticonvulsant hypersensitivity syndrome presenting as aseptic meningitis. ( Bazaz, R; Lily, O; Maniyar, F; Rooney, C, 2009)
"This syndrome is accompanied by fever, rash, lymphadenopathy, eosinophilia and affects parenchymal organs."1.32[Anticonvulsant hypersensitivity syndrome]. ( Papp, Z; Török, L, 2004)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (56.25)29.6817
2010's5 (31.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Ragavendran, JV1
Sriram, D1
Kotapati, S1
Stables, J1
Yogeeswari, P1
Velu, D1
Kantamneni, L1
Batool, SS1
Hachem, A1
Abdelnabi, M1
Elmssary, M1
Sekhon, J1
Benjanuwattra, J1
Iriki, H1
Ouchi, T1
Ito, H1
Sawada, M1
Mukai, M1
Nomura, H1
Baba, Y1
Adachi, T1
Funakoshi, T1
Amagai, M1
Takahashi, H1
Nathan, K1
Agarwal, A1
Gable, B1
McFarland, M1
Wang, XQ1
Lv, B1
Wang, HF1
Zhang, X1
Yu, SY1
Huang, XS1
Zhang, JT1
Tian, CL1
Lang, SY1
Serati Shirazi, Z1
Inaloo, S1
Maniyar, F1
Rooney, C1
Lily, O1
Bazaz, R1
Taillia, H1
Alla, P1
Fournier, B1
Bounolleau, P1
Ouologem, M1
Ricard, D1
Sallansonnet-Froment, M1
de Greslan, T1
Renard, JL1
Ferguson, LP1
Dargan, PI1
Hood, JL1
Tibby, SM1
Pereira de Silva, N1
Piquioni, P1
Kochen, S1
Saidon, P1
Simms, KM1
Kortepeter, C1
Avigan, M1
Papp, Z1
Török, L1
Nesseler, N1
Polard, E1
Arvieux, C1
Coquerel, N1
Michelet, C1
Tattevin, P1
Sabroe, TP1
Sabers, A1
Wensween, CA1
Bouwes Bavinck, JN1

Reviews

1 review available for lamotrigine and Fever

ArticleYear
Lamotrigine induced DIHS/DRESS: Manifestations, treatment, and outcome in 57 patients.
    Clinical neurology and neurosurgery, 2015, Volume: 138

    Topics: Adrenal Cortex Hormones; Anticonvulsants; Drug Hypersensitivity Syndrome; Female; Fever; Humans; Lam

2015

Other Studies

15 other studies available for lamotrigine and Fever

ArticleYear
Newer GABA derivatives for the treatment of epilepsy including febrile seizures: a bioisosteric approach.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:12

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Dru

2008
Lamotrigine-associated haemophagocytic lymphohistiocytosis (HLH) confounded with underlying rheumatoid arthritis.
    BMJ case reports, 2022, Mar-09, Volume: 15, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Arthritis, Rheumatoid; Child; Female; Fever; Humans; Lamotrigine; Lymp

2022
Acute onset of fever, eosinophilia, rash, acute kidney injury, and a positive Monospot test in a patient on lamotrigine: DRESS syndrome.
    Lancet (London, England), 2022, 05-14, Volume: 399, Issue:10338

    Topics: Acute Kidney Injury; Anticonvulsants; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; Fever

2022
Case of lamotrigine-induced drug adverse reaction under tocilizumab treatment with clinical and virological features of drug-induced hypersensitivity syndrome.
    The Journal of dermatology, 2018, Volume: 45, Issue:6

    Topics: Adult; Antibodies, Monoclonal, Humanized; Anticonvulsants; Arthritis, Rheumatoid; Biopsy; C-Reactive

2018
Lamotrigine-induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS).
    BMJ case reports, 2015, Jun-08, Volume: 2015

    Topics: Anticonvulsants; Drug Hypersensitivity Syndrome; Eosinophils; Exanthema; Female; Fever; Humans; Lamo

2015
Intravenous immunoglobulin in the treatment of lamotrigine- induced toxic epidermal necrolysis.
    Iranian journal of allergy, asthma, and immunology, 2008, Volume: 7, Issue:4

    Topics: Blister; Child; Exanthema; Female; Fever; Humans; Immunoglobulins, Intravenous; Lamotrigine; Seizure

2008
Anticonvulsant hypersensitivity syndrome presenting as aseptic meningitis.
    Journal of neurology, 2009, Volume: 256, Issue:7

    Topics: Anti-Bacterial Agents; Anticonvulsants; Drug Administration Schedule; Drug-Related Side Effects and

2009
[Anticonvulsant hypersensitivity syndrome and lamotrigine-associated anticonvulsant hypersensitivity syndrome].
    Revue neurologique, 2009, Volume: 165, Issue:10

    Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Drug Hypersensitivity; Eosinophilia;

2009
Life-threatening organ failure after lamotrigine therapy.
    Pediatric neurology, 2009, Volume: 40, Issue:5

    Topics: Anticonvulsants; Child; Contraindications; Drug Therapy, Combination; Exanthema; Female; Fever; Huma

2009
Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs.
    European journal of clinical pharmacology, 2011, Volume: 67, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anticonvulsants; Carbamazepine; Disease Susceptibility;

2011
Lamotrigine and aseptic meningitis.
    Neurology, 2012, Mar-20, Volume: 78, Issue:12

    Topics: Adolescent; Adult; Aged; Algorithms; Animals; Anticonvulsants; Antidepressive Agents; Bipolar Disord

2012
[Anticonvulsant hypersensitivity syndrome].
    Orvosi hetilap, 2004, Aug-08, Volume: 145, Issue:32

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug

2004
Aseptic meningitis associated with lamotrigine: report of two cases.
    European journal of neurology, 2007, Volume: 14, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anticonvulsants; Blood; Blood Chemical Analysis; Cerebros

2007
Progressive anticonvulsant hypersensitivity syndrome associated with change of drug product.
    Acta neurologica Scandinavica, 2008, Volume: 117, Issue:6

    Topics: Adult; Anticonvulsants; Arthralgia; Arthritis; Drugs, Generic; Epilepsy; Exanthema; Fever; Humans; L

2008
[Overlapping acute disseminated exanthematous pustulosis and toxic epidermal necrolysis].
    Nederlands tijdschrift voor geneeskunde, 2001, Aug-04, Volume: 145, Issue:31

    Topics: Acute Disease; Adult; Anticonvulsants; Diagnosis, Differential; Exanthema; Female; Fever; Humans; La

2001