hydroxyindoleacetic acid has been researched along with Fever in 30 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The predominant histotype was carcinoid, although a few cases had malignant islet cell tumors, medullary thyroid carcinoma, Merkel cell carcinoma, or other neuroendocrine tumors." | 2.67 | Treatment of metastatic carcinoids and other neuroendocrine tumors with recombinant interferon-alpha-2a. A study by the Italian Trials in Medical Oncology Group. ( Bajetta, E; Bochicchio, AM; Buzzoni, R; Castellani, R; Celio, L; Di Bartolomeo, M; Di Leo, A; Dogliotti, L; Pilotti, S; Zilembo, N, 1993) |
| " THC unexpectedly produced a modest hyperthermic effect when administered alone, but in animals co-treated with both THC and MDMA, there was an attenuation of MDMA-induced hyperthermia on dosing days." | 1.37 | Chronic administration of THC prevents the behavioral effects of intermittent adolescent MDMA administration and attenuates MDMA-induced hyperthermia and neurotoxicity in rats. ( Ali, SF; Meyer, JS; Shen, EY, 2011) |
| " These results extend our recent findings of additive toxic effects when METH is combined with MDMA." | 1.33 | MDMA ('Ecstasy') and methamphetamine combined: order of administration influences hyperthermic and long-term adverse effects in female rats. ( Clemens, KJ; Cornish, JL; Hunt, GE; Li, KM; McGregor, IS, 2005) |
| " Rats that did not become hyperthermic when dosed with 15 mg/kg AMPH in a cold environment (10 degrees C) exhibited some hyperactivity and stereotypic behavior, but not overt convulsive behavior." | 1.31 | Seizure activity and hyperthermia potentiate the increases in dopamine and serotonin extracellular levels in the amygdala during exposure to d-amphetamine. ( Bowyer, JF; Tor-Agbidye, J; Yamamoto, B, 2001) |
| "[3H]-paroxetine binding was also decreased by 27% in the cortex, indicating that the amine loss reflected a neurodegenerative change." | 1.29 | The hyperthermic and neurotoxic effects of 'Ecstasy' (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype. ( Colado, MI; Green, AR; Williams, JL, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (23.33) | 18.7374 |
| 1990's | 9 (30.00) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 5 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Michelerio, A | 1 |
| Derlino, F | 1 |
| Brazzelli, V | 1 |
| Vassallo, C | 1 |
| Alves, E | 1 |
| Binienda, Z | 1 |
| Carvalho, F | 1 |
| Alves, CJ | 1 |
| Fernandes, E | 1 |
| de Lourdes Bastos, M | 1 |
| Tavares, MA | 1 |
| Summavielle, T | 1 |
| Piper, BJ | 1 |
| Ali, SF | 3 |
| Daniels, LG | 1 |
| Meyer, JS | 2 |
| Jaehne, EJ | 1 |
| Majumder, I | 1 |
| Salem, A | 1 |
| Irvine, RJ | 1 |
| Wallinga, AE | 1 |
| Grahlmann, C | 1 |
| Granneman, RA | 1 |
| Koolhaas, JM | 1 |
| Buwalda, B | 1 |
| Shen, EY | 1 |
| Clemens, KJ | 2 |
| Van Nieuwenhuyzen, PS | 1 |
| Li, KM | 2 |
| Cornish, JL | 2 |
| Hunt, GE | 2 |
| McGregor, IS | 2 |
| O'Shea, E | 3 |
| Sanchez, V | 1 |
| Orio, L | 1 |
| Escobedo, I | 1 |
| Green, AR | 4 |
| Colado, MI | 3 |
| McNamara, R | 1 |
| Kerans, A | 1 |
| O'Neill, B | 1 |
| Harkin, A | 1 |
| Goni-Allo, B | 1 |
| O Mathúna, B | 1 |
| Segura, M | 1 |
| Puerta, E | 1 |
| Lasheras, B | 1 |
| de la Torre, R | 1 |
| Aguirre, N | 1 |
| Williams, JL | 1 |
| Bajetta, E | 1 |
| Zilembo, N | 1 |
| Di Bartolomeo, M | 1 |
| Di Leo, A | 1 |
| Pilotti, S | 1 |
| Bochicchio, AM | 1 |
| Castellani, R | 1 |
| Buzzoni, R | 1 |
| Celio, L | 1 |
| Dogliotti, L | 1 |
| Sprague, JE | 1 |
| Johnson, MP | 1 |
| Schmidt, CJ | 1 |
| Nichols, DE | 1 |
| Newport, GD | 1 |
| Slikker, W | 2 |
| Malberg, JE | 2 |
| Seiden, LS | 2 |
| Granados, R | 1 |
| Esteban, B | 1 |
| Yeh, SY | 1 |
| Dersch, C | 1 |
| Rothman, R | 1 |
| Cadet, JL | 1 |
| Stewart, CW | 1 |
| Tor-Agbidye, J | 1 |
| Yamamoto, B | 1 |
| Bowyer, JF | 1 |
| Johkura, K | 1 |
| Hasegawa, O | 1 |
| Kuroiwa, Y | 1 |
| Easton, N | 1 |
| Fry, JR | 1 |
| Marsden, CA | 1 |
| Gardey-Levassort, C | 1 |
| Tanguy, O | 1 |
| Lechat, P | 1 |
| Hahn, Z | 1 |
| Székely, M | 1 |
| Scheel-Krüger, J | 1 |
| Hasselager, E | 1 |
| Peters, DA | 1 |
| Hrdina, PD | 1 |
| Singhal, RL | 1 |
| Ling, GM | 1 |
| Blatteis, CM | 1 |
| Billmeier, GJ | 1 |
| Gilbert, TM | 1 |
| Squires, RF | 1 |
| Machtey, I | 1 |
1 trial available for hydroxyindoleacetic acid and Fever
| Article | Year |
|---|---|
Treatment of metastatic carcinoids and other neuroendocrine tumors with recombinant interferon-alpha-2a. A study by the Italian Trials in Medical Oncology Group.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoid Tumor; Drug Administration Schedule; Female; Fever; Humans | 1993 |
29 other studies available for hydroxyindoleacetic acid and Fever
| Article | Year |
|---|---|
Secondary erythromelalgia: a tryptophan dietary supplement-induced case associated with elevated 5-hydroxyindoleacetic acid (5HIAA) urinary levels.
Topics: Adult; Dietary Supplements; Erythromelalgia; Fever; Follow-Up Studies; Foot; Hand; Humans; Hydroxyin | 2018 |
Acetyl-L-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain.
Topics: Acetylcarnitine; Animals; Body Weight; Brain; Cyclooxygenase 1; DNA, Mitochondrial; Fever; Hallucino | 2009 |
Repeated intermittent methylenedioxymethamphetamine exposure protects against the behavioral and neurotoxic, but not hyperthermic, effects of an MDMA binge in adult rats.
Topics: Age Factors; Animals; Binding, Competitive; Body Temperature; Cerebral Cortex; Citalopram; Dose-Resp | 2010 |
Increased effects of 3,4-methylenedioxymethamphetamine (ecstasy) in a rat model of depression.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arousal; Body Temperature Regulation; Brain; Cerebral Corte | 2011 |
Gender differences in hyperthermia and regional 5-HT and 5-HIAA depletion in the brain following MDMA administration in rats.
Topics: Animals; Brain; Disease Models, Animal; Female; Fever; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4- | 2011 |
Chronic administration of THC prevents the behavioral effects of intermittent adolescent MDMA administration and attenuates MDMA-induced hyperthermia and neurotoxicity in rats.
Topics: Adrenergic Uptake Inhibitors; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Behavior | 2011 |
MDMA ("ecstasy"), methamphetamine and their combination: long-term changes in social interaction and neurochemistry in the rat.
Topics: Animals; Anxiety; Behavior, Animal; Body Temperature; Corpus Striatum; Dopamine; Dopamine Agents; Dr | 2004 |
MDMA ('Ecstasy') and methamphetamine combined: order of administration influences hyperthermic and long-term adverse effects in female rats.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Brain Chemistry; Central Nervous System Stimulan | 2005 |
3,4-Methylenedioxymethamphetamine increases pro-interleukin-1beta production and caspase-1 protease activity in frontal cortex, but not in hypothalamus, of Dark Agouti rats: role of interleukin-1beta in neurotoxicity.
Topics: Animals; Blotting, Western; Caspase 1; Chromatography, High Pressure Liquid; Fever; Frontal Lobe; Ha | 2005 |
Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA ("Ecstasy") and MDA ("Love").
Topics: 3,4-Methylenedioxyamphetamine; Animals; Area Under Curve; Behavior, Animal; Body Temperature; Brain | 2006 |
The relationship between core body temperature and 3,4-methylenedioxymethamphetamine metabolism in rats: implications for neurotoxicity.
Topics: Animals; Body Temperature; Brain Chemistry; Catechol O-Methyltransferase; Catechol O-Methyltransfera | 2008 |
The hyperthermic and neurotoxic effects of 'Ecstasy' (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Body Temperature Regulation; Brain; Cytochrome P-450 CYP2D6; | 1995 |
Studies on the mechanism of p-chloroamphetamine neurotoxicity.
Topics: Animals; Brain; Clorgyline; Dopamine; Fever; Hydroxyindoleacetic Acid; Indans; Male; Monoamine Oxida | 1996 |
Methamphetamine-induced dopaminergic toxicity in mice. Role of environmental temperature and pharmacological agents.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Diazepam; Dizocilpine Maleate; Dopamine; F | 1996 |
Administration of fenfluramine at different ambient temperatures produces different core temperature and 5-HT neurotoxicity profiles.
Topics: Animals; Body Temperature Regulation; Brain; Brain Chemistry; Cell Death; Fenfluramine; Fever; Hydro | 1997 |
Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Body Temperature Regulation; Brain Chemis | 1998 |
Role of hyperthermia in the protective action of clomethiazole against MDMA ('ecstasy')-induced neurodegeneration, comparison with the novel NMDA channel blocker AR-R15896AR.
Topics: Animals; Body Temperature; Brain Chemistry; Chlormethiazole; Excitatory Amino Acid Antagonists; Feve | 1998 |
Effects of antihistamines on 3, 4-methylenedioxymethamphetamine-induced depletion of serotonin in rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Body Temperature; Brain Chemistry; Chlorpheniramine; Fever; H | 1999 |
Hyperthermia-enhanced serotonin (5-HT) depletion resulting from D-fenfluramine (D-Fen) exposure does not evoke a glial-cell response in the central nervous system of rats.
Topics: Animals; Brain Chemistry; Fenfluramine; Fever; Frontal Lobe; Glial Fibrillary Acidic Protein; Gliosi | 1999 |
Seizure activity and hyperthermia potentiate the increases in dopamine and serotonin extracellular levels in the amygdala during exposure to d-amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Amygdala; Animals; Behavior, Animal; Chromatography, Hi | 2001 |
Episodic encephalopathy with dilated pupils.
Topics: Adult; Brain Diseases, Metabolic; Confusion; Fever; Humans; Hydroxyindoleacetic Acid; Male; Mydriasi | 2001 |
Protection against 3,4-methylenedioxymethamphetamine-induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia.
Topics: Animals; Brain; Brain Chemistry; Buthionine Sulfoximine; Drug Therapy, Combination; Fever; Glutathio | 2002 |
Brain concentrations of biogenic amines and their metabolites in two types of pyrogen-induced fever in rabbits.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Stem; Caudate Nucleus; Dopamine; Escherichia c | 1977 |
Hypothalamic monoamine contents in endotoxin fever of new-born guinea pigs and kittens.
Topics: Animals; Biogenic Amines; Cats; Endotoxins; Escherichia coli; Fever; Guinea Pigs; Hydroxyindoleaceti | 1979 |
Studies of various amphetamines, apomorphine and clonidine on body temperature and brain 5-hydroxytryptamine metabolism in rats.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Body Temperature; Brain; Brain Chemistry; Carbo | 1974 |
The role of brain serotonin in DDT-induced hyperpyrexia.
Topics: Animals; Brain; Brain Stem; DDT; Fenclonine; Fever; Fluorine; Hydroxyindoleacetic Acid; Male; Pargyl | 1972 |
Thermoregulation of phenylketonuric children.
Topics: Adolescent; Body Temperature Regulation; Child, Preschool; Female; Fever; Humans; Hydroxyindoleaceti | 1974 |
Hyperthermia- and L-tryptophan-induced increases in serotonin turnover in rat brain.
Topics: Animals; Brain; Brain Chemistry; Fever; Hydroxyindoleacetic Acid; Male; Neurons; Rats; Serotonin; Tr | 1974 |
[Pyrexia following nialamide].
Topics: Female; Fever; Humans; Hydroxyindoleacetic Acid; Middle Aged; Nialamide | 1968 |