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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Fever

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Fever in 4 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
" The anti-inflammatory potency of NS-398 in rat carrageenin-induced edema was as potent as that of indomethacin and 8 times more potent than diclofenac."3.68NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. ( Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K, 1993)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Friesen, RW1
Mancini, JA1
Futaki, N1
Yoshikawa, K1
Hamasaka, Y1
Arai, I1
Higuchi, S1
Iizuka, H1
Otomo, S1
Matsumura, K2
Cao, C2
Watanabe, Y2
Yamagata, K1

Other Studies

4 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Fever

ArticleYear
Microsomal prostaglandin E2 synthase-1 (mPGES-1): a novel anti-inflammatory therapeutic target.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Fever; Humans; Intramolecular Oxi

2008
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
    General pharmacology, 1993, Volume: 24, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygena

1993
Possible role of cyclooxygenase-2 in the brain vasculature in febrile response.
    Annals of the New York Academy of Sciences, 1997, Mar-15, Volume: 813

    Topics: Animals; Brain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprosto

1997
Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2

    Topics: Abdomen; Analgesics, Non-Narcotic; Anesthesia; Animals; Blood Vessels; Body Temperature; Brain; Cycl

1997