Page last updated: 2024-10-20

spermine and Fever

spermine has been researched along with Fever in 3 studies

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
"Endogenous concentrations of putrescine, spermidine, spermine and related biosynthetic enzymes were not affected by the administration of bacterial endotoxin and the subsequent development of fever in rabbits."7.67Evidence against putrescine and polyamines as endogenous mediators of fever. ( Dascombe, MJ; Haegele, KD, 1985)
"Endogenous concentrations of putrescine, spermidine, spermine and related biosynthetic enzymes were not affected by the administration of bacterial endotoxin and the subsequent development of fever in rabbits."3.67Evidence against putrescine and polyamines as endogenous mediators of fever. ( Dascombe, MJ; Haegele, KD, 1985)
"Twenty-nine patients were treated with DENSPM using a dosing schedule of once daily for 5 days."2.70Phase I study of N(1),N(11)-diethylnorspermine in patients with non-small cell lung cancer. ( Bowling, K; Casero, RA; Chen, TL; Ettinger, DS; Hahm, HA; Hoker, B; Zabelina, Y, 2002)
" We investigated a new strategy to overcome multidrug resistance, using purified bovine serum amine oxidase, which generates two major toxic products from the polyamine spermine."1.31Amine oxidase, spermine, and hyperthermia induce cytotoxicity in P-glycoprotein overexpressing multidrug resistant Chinese hamster ovary cells. ( Agostinelli, E; Averill-Bates, DA; Lord-Fontaine, S; Przybytkowski, E, 2001)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lord-Fontaine, S1
Agostinelli, E1
Przybytkowski, E1
Averill-Bates, DA1
Hahm, HA1
Ettinger, DS1
Bowling, K1
Hoker, B1
Chen, TL1
Zabelina, Y1
Casero, RA1
Dascombe, MJ1
Haegele, KD1

Trials

1 trial available for spermine and Fever

ArticleYear
Phase I study of N(1),N(11)-diethylnorspermine in patients with non-small cell lung cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Dose-Response

2002

Other Studies

2 other studies available for spermine and Fever

ArticleYear
Amine oxidase, spermine, and hyperthermia induce cytotoxicity in P-glycoprotein overexpressing multidrug resistant Chinese hamster ovary cells.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2001, Volume: 79, Issue:2

    Topics: Aldehydes; Amine Oxidase (Copper-Containing); Animals; ATP Binding Cassette Transporter, Subfamily B

2001
Evidence against putrescine and polyamines as endogenous mediators of fever.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:5

    Topics: Animals; Eflornithine; Endotoxins; Fever; Ornithine; Polyamines; Putrescine; Rabbits; Shigella dysen

1985