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diclofenac and Fever

diclofenac has been researched along with Fever in 48 studies

Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
"Twenty-two febrile comatose patients: 12 severe traumatic brain injury and 10 subarachnoid hemorrhage divided in 2 groups: Diclofenac low-dose infusion (10 patients) and extemporaneous boluses of NSAIDs (CTRL, 12 patients)."9.12Continuous low dose diclofenac sodium infusion to control fever in neurosurgical critical care. ( Citerio, G; Cormio, M, 2007)
" The role of COX-2 in the genesis of fever in monkeys and humans was examined with use of the specific COX-2 inhibitor rofecoxib."9.09Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans. ( Adcock, S; Bachmann, KA; Chan, CC; Cohen, RA; Davidson, MH; Dobratz, D; Gertz, BJ; Grasing, K; Hedges, J; Jones, TM; McBride, KJ; Moritz, C; Mukhopadhyay, S; Schwartz, JI, 1999)
"We observed that a low-dose diclofenac sodium infusion was effective in treating fever without systemic side effects."9.01Continuous intravenous low-dose diclofenac sodium to control a central fever after ischemic stroke in the intensive care unit: a case report and review of the literature. ( Aurilio, C; Esposito, V; Giaccari, LG; Pace, MC; Passavanti, MB; Pota, V; Sansone, P, 2019)
"To evaluate the cerebral and hemodynamic effects of low-dose intramuscular diclofenac sodium (DCFS) administered for fever control in patients with acute brain injury in the intensive care unit."7.83Low-Dose Intramuscular Diclofenac Sodium for Fever Control in Acute Brain Injury. ( Antonini, MV; Caspani, ML; De Carlo, F; Picetti, E; Reverberi, C; Rossi, I; Servadei, F, 2016)
"It was previously shown that sustained fever can be induced in rats by central injection of endothelin-1 (ET-1)."7.73The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats. ( Cristofoletti, R; Fabricio, AS; Navarra, P; Souza, GE; Veiga, FH, 2005)
"Therapeutic effect of sodium diclofenac during fever reaction is associated not only with specific modulation of thermoregulation, but also with the increase in the count of lymphocytes transported with the lymph into systemic circulation, stimulation of lymph microcirculation, and improvement of metabolism in the interstitial space."7.73Effect of sodium diclofenac on microcirculation and composition of the lymph during fever reaction. ( Mukhutdinova, FI; Tagirova, DR, 2005)
" Well documented safety and efficacy, a rapid onset of action and a flexible daily dosing regimen are essential in this context."6.44Diclofenac potassium 12.5mg tablets for mild to moderate pain and fever: a review of its pharmacology, clinical efficacy and safety. ( Moore, N, 2007)
"Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) advocated for use in painful and inflammatory rheumatic and certain non-rheumatic conditions."6.16Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. ( Sorkin, EM; Todd, PA, 1988)
"(1) Renal colic is an acute syndrome involving unilateral flank pain, linked to an obstruction in the upper urinary tract."5.35Renal colic in adults: NSAIDs and morphine are effective for pain relief. ( , 2009)
"Twenty-two febrile comatose patients: 12 severe traumatic brain injury and 10 subarachnoid hemorrhage divided in 2 groups: Diclofenac low-dose infusion (10 patients) and extemporaneous boluses of NSAIDs (CTRL, 12 patients)."5.12Continuous low dose diclofenac sodium infusion to control fever in neurosurgical critical care. ( Citerio, G; Cormio, M, 2007)
" The role of COX-2 in the genesis of fever in monkeys and humans was examined with use of the specific COX-2 inhibitor rofecoxib."5.09Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans. ( Adcock, S; Bachmann, KA; Chan, CC; Cohen, RA; Davidson, MH; Dobratz, D; Gertz, BJ; Grasing, K; Hedges, J; Jones, TM; McBride, KJ; Moritz, C; Mukhopadhyay, S; Schwartz, JI, 1999)
"We observed that a low-dose diclofenac sodium infusion was effective in treating fever without systemic side effects."5.01Continuous intravenous low-dose diclofenac sodium to control a central fever after ischemic stroke in the intensive care unit: a case report and review of the literature. ( Aurilio, C; Esposito, V; Giaccari, LG; Pace, MC; Passavanti, MB; Pota, V; Sansone, P, 2019)
"To evaluate the cerebral and hemodynamic effects of low-dose intramuscular diclofenac sodium (DCFS) administered for fever control in patients with acute brain injury in the intensive care unit."3.83Low-Dose Intramuscular Diclofenac Sodium for Fever Control in Acute Brain Injury. ( Antonini, MV; Caspani, ML; De Carlo, F; Picetti, E; Reverberi, C; Rossi, I; Servadei, F, 2016)
"It was previously shown that sustained fever can be induced in rats by central injection of endothelin-1 (ET-1)."3.73The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats. ( Cristofoletti, R; Fabricio, AS; Navarra, P; Souza, GE; Veiga, FH, 2005)
" Efficacy of lumiracoxib in rat models of hyperalgesia, oedema, pyresis and arthritis was dose-dependent and similar to diclofenac."3.73Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2. ( Berry, C; Dawson, J; Du, Z; Esser, R; Fox, A; Fujimoto, RA; Haston, W; Kimble, EF; Koehler, J; Marshall, PJ; Peppard, J; Quadros, E; Quintavalla, J; Toscano, K; Urban, L; van Duzer, J; Zhang, X; Zhou, S, 2005)
" Administration of diclofenac, a nonselective cyclooxygenase (COX) inhibitor, at different doses (5, 50, 500, or 5,000 microg/kg) attenuated or abrogated LPS-induced fever and inhibited LPS-induced local PGE(2) formation (5 or 500 microg/kg diclofenac)."3.73Localized vs. systemic inflammation in guinea pigs: a role for prostaglandins at distinct points of the fever induction pathways? ( Barth, SW; Gerstberger, R; Hübschle, T; Korte, S; Roth, J; Rummel, C; Voss, T, 2005)
"Therapeutic effect of sodium diclofenac during fever reaction is associated not only with specific modulation of thermoregulation, but also with the increase in the count of lymphocytes transported with the lymph into systemic circulation, stimulation of lymph microcirculation, and improvement of metabolism in the interstitial space."3.73Effect of sodium diclofenac on microcirculation and composition of the lymph during fever reaction. ( Mukhutdinova, FI; Tagirova, DR, 2005)
" The anti-inflammatory potency of NS-398 in rat carrageenin-induced edema was as potent as that of indomethacin and 8 times more potent than diclofenac."3.68NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. ( Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K, 1993)
" Two transcervical intra-uterine insertions of 216 mg of quinacrine, carried out at an interval of one month and associated with 50 mg of intra-uterine diclofenac and 150 mg of intra-muscular diclofenac resulted in a pregnancy rate after 12 months of 2."3.68[Non-surgical female sterilization using quinacrine: efficacy of two insertions of quinacrine pellets]. ( Rivera, M; Trujillo, V; Viel, B; Zipper, J, 1993)
"Diclofenac-K was superior to placebo (P < 0."2.71A multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled, parallel-group comparison of diclofenac-K and ibuprofen for the treatment of adults with influenza-like symptoms. ( Frank, WO; Gold, MS; Grebe, W; Ionescu, E; Liu, JM, 2003)
"Fever is a common symptom in cancer patients."2.70Symptomatic intravenous antipyretic therapy: efficacy of metamizol, diclofenac, and propacetamol. ( Korístek, Z; Mayer, J; Oborilová, A; Pospísil, Z, 2002)
"Paraneoplastic fever is well known, and is not an uncommon problem in daily practice."2.67A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever. ( Bacojanis, C; Beldecos, D; Karabelis, A; Karvounis, N; Kosmidis, P; Milonacis, N; Tsavaris, N; Zinelis, A, 1990)
" Well documented safety and efficacy, a rapid onset of action and a flexible daily dosing regimen are essential in this context."2.44Diclofenac potassium 12.5mg tablets for mild to moderate pain and fever: a review of its pharmacology, clinical efficacy and safety. ( Moore, N, 2007)
"Fever is common in patients with acute brain injury and worsens secondary brain injury and clinical outcomes."1.51A Survey on Fever Monitoring and Management in Patients With Acute Brain Injury: The SUMMA Study. ( Helbok, R; Oddo, M; Picetti, E; Prisco, L; Taccone, FS, 2019)
"(1) Renal colic is an acute syndrome involving unilateral flank pain, linked to an obstruction in the upper urinary tract."1.35Renal colic in adults: NSAIDs and morphine are effective for pain relief. ( , 2009)
"A patient with rheumatoid arthritis is described who presented with low-grade fever for 3 months, in whom Actinobacillus ureae was cultured from bone marrow aspirate."1.30Bone marrow infection caused by Actinobacillus ureae in a rheumatoid arthritis patient. ( Avlami, A; Dounis, E; Kordossis, T; Papalambrou, C; Tzivra, M, 1997)
"Diclofenac sodium proved to be a very potent antipyretic agent with serious side effects."1.27Antipyretic therapy with diclofenac sodium. Observations on effect and serious side effects in critically ill patients. ( Alexander, JP; Stoutenbeek, CP; Zandstra, DF, 1983)
" We conclude that the proposed dosage (in the selected patient population) constitutes effective antipyretic treatment devoid of major side effects."1.27Antipyretic therapy in ICU patients: evaluation of low dose diclofenac sodium. ( Basilico, E; Grossi, E; Pesenti, A; Riboni, A, 1986)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199011 (22.92)18.7374
1990's7 (14.58)18.2507
2000's24 (50.00)29.6817
2010's6 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giaccari, LG1
Pace, MC1
Passavanti, MB1
Sansone, P1
Esposito, V1
Aurilio, C1
Pota, V1
Schiefecker, AJ1
Rass, V1
Gaasch, M1
Kofler, M1
Thomé, C1
Humpel, C1
Ianosi, B1
Hackl, WO1
Beer, R1
Pfausler, B1
Schmutzhard, E1
Helbok, R2
Picetti, E2
Oddo, M1
Prisco, L1
Taccone, FS1
Polukonova, NV1
Navolokin, NA1
Raĭkova, SV1
Masliakova, GN1
Bucharskaia, AB1
Durnova, NA1
Shub, GM1
Servadei, F1
Reverberi, C1
De Carlo, F1
Rossi, I1
Antonini, MV1
Caspani, ML1
Niazi, J1
Singh, P1
Bansal, Y1
Goel, RK1
Marais, M1
Maloney, SK3
Gray, DA3
Ross, G2
Hübschle, T4
Pehl, U2
Braun, HA1
Voigt, K1
Gerstberger, R4
Roth, J4
Oborilová, A1
Mayer, J1
Pospísil, Z1
Korístek, Z1
Dogan, MD1
Ataoglu, H1
Akarsu, ES1
Grebe, W1
Ionescu, E1
Gold, MS1
Liu, JM1
Frank, WO1
Aleksandrov, PN1
Mukhutdinova, FI2
Tagirova, DR2
Mukhutdinov, DA1
Caricato, A1
Conti, G1
Mercurio, G1
Mancino, A1
Santilli, F1
Antonelli, M1
Proietti, R1
Fabricio, AS1
Veiga, FH1
Cristofoletti, R1
Navarra, P1
Souza, GE1
Esser, R1
Berry, C1
Du, Z1
Dawson, J1
Fox, A1
Fujimoto, RA1
Haston, W1
Kimble, EF1
Koehler, J1
Peppard, J1
Quadros, E1
Quintavalla, J1
Toscano, K1
Urban, L1
van Duzer, J1
Zhang, X1
Zhou, S1
Marshall, PJ1
Rummel, C1
Barth, SW1
Voss, T1
Korte, S1
Kamerman, PR2
Okumura, A1
Fukumoto, Y1
Hayakawa, F1
Nakano, T1
Higuchi, K1
Kamiya, H1
Watanabe, K1
Morishima, T1
Rüster, M1
Kiehntopf, M1
Gröne, HJ1
Wolf, G1
Daud, A1
Habib, N1
Riera, AS1
Moore, N1
Greis, A1
Murgott, J1
Rafalzik, S1
Greer, DM1
Cormio, M2
Citerio, G2
Zandstra, DF2
Stoutenbeek, CP2
Alexander, JP1
Dittmer, A1
Polman, HA1
Huijbers, WA1
Augusteijn, R1
Futaki, N1
Yoshikawa, K1
Hamasaka, Y1
Arai, I1
Higuchi, S1
Iizuka, H1
Otomo, S1
Trujillo, V1
Zipper, J1
Viel, B1
Rivera, M1
Avlami, A1
Papalambrou, C1
Tzivra, M1
Dounis, E1
Kordossis, T1
Kido, H1
Murakami, N1
Ito, A1
Kimura, K1
Kodera, N1
Doi, T1
Naruse, T1
Schwartz, JI1
Chan, CC1
Mukhopadhyay, S1
McBride, KJ1
Jones, TM1
Adcock, S1
Moritz, C1
Hedges, J1
Grasing, K1
Dobratz, D1
Cohen, RA1
Davidson, MH1
Bachmann, KA1
Gertz, BJ1
Enrique, E1
Cisteró-Bahima, A1
Alonso, R1
Bravo, P1
Fenollosa, A1
Torre, I1
Spear, S1
Fumagalli, R1
Pesenti, A2
Tsavaris, N1
Zinelis, A1
Karabelis, A1
Beldecos, D1
Bacojanis, C1
Milonacis, N1
Karvounis, N1
Kosmidis, P1
McGalliard, J1
Bell, AL1
Cedrato, AE1
Passarelli, I1
Cimollini, L1
Maccarone, H1
Scholer, DW2
Ku, EC2
Boettcher, I2
Schweizer, A2
Todd, PA1
Sorkin, EM1
Bettini, R1
Grossi, E2
Rapazzini, P1
Giardina, G1
Riboni, A1
Basilico, E1
Wouters, JM1
van Rijswijk, MH1
van de Putte, LB1

Reviews

4 reviews available for diclofenac and Fever

ArticleYear
Continuous intravenous low-dose diclofenac sodium to control a central fever after ischemic stroke in the intensive care unit: a case report and review of the literature.
    Journal of medical case reports, 2019, Dec-18, Volume: 13, Issue:1

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Diclofenac; Female; Fever; Humans; In

2019
Diclofenac potassium 12.5mg tablets for mild to moderate pain and fever: a review of its pharmacology, clinical efficacy and safety.
    Clinical drug investigation, 2007, Volume: 27, Issue:3

    Topics: Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Fever; Humans; Molecular St

2007
[Body temperature and fever--body temperature regulation, indications and possibilities of fever reducing therapy. II. Indications and effects of fever-lowering procedures and fever-reducing drug therapy].
    Kinderarztliche Praxis, 1981, Volume: 49, Issue:3

    Topics: Acetaminophen; Age Factors; Aminopyrine; Body Temperature Regulation; Child; Child, Preschool; Diclo

1981
Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
    Drugs, 1988, Volume: 35, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; D

1988

Trials

10 trials available for diclofenac and Fever

ArticleYear
Symptomatic intravenous antipyretic therapy: efficacy of metamizol, diclofenac, and propacetamol.
    Journal of pain and symptom management, 2002, Volume: 24, Issue:6

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammato

2002
A multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled, parallel-group comparison of diclofenac-K and ibuprofen for the treatment of adults with influenza-like symptoms.
    Clinical therapeutics, 2003, Volume: 25, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Administration

2003
Continuous low dose diclofenac sodium infusion to control fever in neurosurgical critical care.
    Neurocritical care, 2007, Volume: 6, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Brain Injuries; Critical Care;

2007
The use of diclofenac sodium (Voltaren) suppositories as an antipyretic in children with fever due to acute infections: a double-blind, between-patient, placebo-controlled study.
    The Journal of international medical research, 1981, Volume: 9, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections; Child; Child, Preschool; Clinical Tri

1981
Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans.
    Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:6

    Topics: Administration, Oral; Analysis of Variance; Animals; Body Temperature; Cyclooxygenase 2; Cyclooxygen

1999
Diclofenac-induced fever.
    Allergy, 2000, Volume: 55, Issue:4

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Chlorpheniramine; Diclofenac; Drug Hypers

2000
A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever.
    Journal of internal medicine, 1990, Volume: 228, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Fever; Humans; Indomethacin; Male; Napr

1990
[Comparison of the antipyretic effect of a single dose of dipyrone, paracetamol and diclofenac resinate. A multicenter clinical trial].
    Medicina, 1989, Volume: 49, Issue:6

    Topics: Acetaminophen; Body Temperature; Child; Child, Preschool; Diclofenac; Dipyrone; Female; Fever; Human

1989
Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
    Drugs, 1988, Volume: 35, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; D

1988
Diclofenac sodium versus acetylsalicylic acid: a randomized study in febrile patients.
    The Journal of international medical research, 1986, Volume: 14, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diclofenac; Drug

1986

Other Studies

35 other studies available for diclofenac and Fever

ArticleYear
Brain Extracellular Interleukin-6 Levels Decrease Following Antipyretic Therapy with Diclofenac in Patients with Spontaneous Subarachnoid Hemorrhage.
    Therapeutic hypothermia and temperature management, 2019, Volume: 9, Issue:1

    Topics: Aged; Antipyretics; Body Temperature; Brain Chemistry; Dialysis; Diclofenac; Extracellular Space; Fe

2019
A Survey on Fever Monitoring and Management in Patients With Acute Brain Injury: The SUMMA Study.
    Journal of neurosurgical anesthesiology, 2019, Volume: 31, Issue:4

    Topics: Acetaminophen; Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Body Tem

2019
[AntI-inflammatory, antipyretic and antimicrobial activity of flavonoid-containing extract of Gratiola officinalis L].
    Eksperimental'naia i klinicheskaia farmakologiia, 2015, Volume: 78, Issue:1

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antipyretics; Diclofenac; Edema; Fever; Fl

2015
Low-Dose Intramuscular Diclofenac Sodium for Fever Control in Acute Brain Injury.
    World neurosurgery, 2016, Volume: 95

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Diclofenac; Female; Fever; Humans; I

2016
Anti-inflammatory, analgesic and antipyretic activity of aqueous extract of fresh leaves of Coccinia indica.
    Inflammopharmacology, 2009, Volume: 17, Issue:4

    Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Cucurbitacea

2009
Renal colic in adults: NSAIDs and morphine are effective for pain relief.
    Prescrire international, 2009, Volume: 18, Issue:103

    Topics: Acetaminophen; Adult; Analgesia; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clinic

2009
Brain IL-6- and PG-dependent actions of IL-1β and lipopolysaccharide in avian fever.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 301, Issue:3

    Topics: Analysis of Variance; Animals; Antibodies; Body Temperature Regulation; Brain; Cyclooxygenase Inhibi

2011
Fever induction by localized subcutaneous inflammation in guinea pigs: the role of cytokines and prostaglandins.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:4

    Topics: Animals; Carrier Proteins; Cyclooxygenase Inhibitors; Cytokines; Diclofenac; Drug Combinations; Drug

2003
Nimesulide and diclofenac inhibit lipopolysaccharide-induced hypothermia and tumour necrosis factor-alpha elevation in rats.
    Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:4

    Topics: Analysis of Variance; Animals; Body Temperature Regulation; Cyclooxygenase 2; Cyclooxygenase 2 Inhib

2002
Effect of orthophen on microlymphocirculation during fever reaction.
    Bulletin of experimental biology and medicine, 2004, Volume: 137, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Fever; Lymph; Lymphatic System

2004
Continuous low-dose diclofenac infusion for fever control in patients with acute neurological lesions.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Temperature; Cerebrovascular Circulati

2004
The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 288, Issue:3

    Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Dose-Response Re

2005
Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2.
    British journal of pharmacology, 2005, Volume: 144, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Biological Availability;

2005
Localized vs. systemic inflammation in guinea pigs: a role for prostaglandins at distinct points of the fever induction pathways?
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 289, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibito

2005
Effect of sodium diclofenac on microcirculation and composition of the lymph during fever reaction.
    Bulletin of experimental biology and medicine, 2005, Volume: 139, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Fever; Kallikreins; Kinins; Ly

2005
Lipopolysaccharide-induced fever in Pekin ducks is mediated by prostaglandins and nitric oxide and modulated by adrenocortical hormones.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 289, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Corticosterone; Dexamethasone; Diclofenac; Ducks; Enzyme Inhibito

2005
Antipyretics and delirious behavior during febrile illness.
    Pediatrics international : official journal of the Japan Pediatric Society, 2006, Volume: 48, Issue:1

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Delirium; Diclofenac;

2006
A Friday afternoon case of apparent anti-glomerular basement nephritis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:8

    Topics: Acetaminophen; Acute Kidney Injury; Analgesics; Animals; Anti-Glomerular Basement Membrane Disease;

2006
Anti-inflammatory, anti-nociceptive and antipyretic effects of extracts of Phrygilanthus acutifolius flowers.
    Journal of ethnopharmacology, 2006, Nov-24, Volume: 108, Issue:2

    Topics: Acetic Acid; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-

2006
Characterization of the febrile response induced by fibroblast-stimulating lipopeptide-1 in guinea pigs.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:1

    Topics: Animals; Body Temperature; Cyclooxygenase Inhibitors; Cytokines; Diclofenac; Diglycerides; Dinoprost

2007
Continuous intravenous NSAID administration for fever control.
    Neurocritical care, 2007, Volume: 6, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Critical Care; Diclofenac; Fever; Humans; I

2007
Restraint increases afebrile body temperature but attenuates fever in Pekin ducks (Anas platyrhynchos).
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Body Temperature Regulation; Dic

2008
Antipyretic therapy with diclofenac sodium. Observations on effect and serious side effects in critically ill patients.
    Intensive care medicine, 1983, Volume: 9, Issue:1

    Topics: Acute Disease; Body Temperature; Critical Care; Diclofenac; Fever; Humans; Oliguria; Phenylacetates;

1983
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
    General pharmacology, 1993, Volume: 24, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygena

1993
[Non-surgical female sterilization using quinacrine: efficacy of two insertions of quinacrine pellets].
    Revue francaise de gynecologie et d'obstetrique, 1993, Volume: 88, Issue:3

    Topics: Adult; Diclofenac; Drug Implants; Female; Fever; Headache; Humans; Injections, Intramuscular; Metror

1993
Bone marrow infection caused by Actinobacillus ureae in a rheumatoid arthritis patient.
    The Journal of infection, 1997, Volume: 35, Issue:3

    Topics: Actinobacillus; Actinobacillus Infections; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis,

1997
Anti-inflammatory, analgesic and anti-pyretic effects of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a new non-steroidal anti-inflammatory drug, in rats and guinea pigs.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1998
Control of fever by continuous, low-dose diclofenac sodium infusion in acute cerebral damage patients.
    Intensive care medicine, 2000, Volume: 26, Issue:5

    Topics: Acute Disease; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Craniocerebral

2000
Influence of systemic treatment with cyclooxygenase inhibitors on lipopolysaccharide-induced fever and circulating levels of cytokines and cortisol in guinea-pigs.
    Pflugers Archiv : European journal of physiology, 2002, Volume: 443, Issue:3

    Topics: Animals; Body Temperature Regulation; Cyclooxygenase Inhibitors; Diclofenac; Fever; Guinea Pigs; Hyd

2002
Acquired Brown's syndrome in systemic lupus erythematosus: another ocular manifestation.
    Clinical rheumatology, 1990, Volume: 9, Issue:3

    Topics: Adult; Diclofenac; Diplopia; Fever; Humans; Hydroxychloroquine; Ibuprofen; Lupus Erythematosus, Syst

1990
Pharmacology of diclofenac sodium.
    The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B

    Topics: Analgesics; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diclofenac; Dos

1986
Antipyretic therapy in intensive care.
    Intensive care medicine, 1987, Volume: 13, Issue:5

    Topics: Critical Care; Diclofenac; Fever; Humans; Respiration, Artificial

1987
Antipyretic therapy in ICU patients: evaluation of low dose diclofenac sodium.
    Intensive care medicine, 1986, Volume: 12, Issue:5

    Topics: Body Temperature; Critical Care; Diclofenac; Drug Evaluation; Fever; Hemodynamics; Humans; Kidney; O

1986
Pharmacology of diclofenac sodium (Voltaren).
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimental; Cyclooxygenase Inhibitors; Di

1985
Adult onset Still's disease in the elderly: a report of two cases.
    The Journal of rheumatology, 1985, Volume: 12, Issue:4

    Topics: Aged; Arthritis; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Diagnosis, Differentia

1985