diclofenac and Fever
diclofenac has been researched along with Fever in 48 studies
Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-two febrile comatose patients: 12 severe traumatic brain injury and 10 subarachnoid hemorrhage divided in 2 groups: Diclofenac low-dose infusion (10 patients) and extemporaneous boluses of NSAIDs (CTRL, 12 patients)." | 9.12 | Continuous low dose diclofenac sodium infusion to control fever in neurosurgical critical care. ( Citerio, G; Cormio, M, 2007) |
| " The role of COX-2 in the genesis of fever in monkeys and humans was examined with use of the specific COX-2 inhibitor rofecoxib." | 9.09 | Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans. ( Adcock, S; Bachmann, KA; Chan, CC; Cohen, RA; Davidson, MH; Dobratz, D; Gertz, BJ; Grasing, K; Hedges, J; Jones, TM; McBride, KJ; Moritz, C; Mukhopadhyay, S; Schwartz, JI, 1999) |
| "We observed that a low-dose diclofenac sodium infusion was effective in treating fever without systemic side effects." | 9.01 | Continuous intravenous low-dose diclofenac sodium to control a central fever after ischemic stroke in the intensive care unit: a case report and review of the literature. ( Aurilio, C; Esposito, V; Giaccari, LG; Pace, MC; Passavanti, MB; Pota, V; Sansone, P, 2019) |
| "To evaluate the cerebral and hemodynamic effects of low-dose intramuscular diclofenac sodium (DCFS) administered for fever control in patients with acute brain injury in the intensive care unit." | 7.83 | Low-Dose Intramuscular Diclofenac Sodium for Fever Control in Acute Brain Injury. ( Antonini, MV; Caspani, ML; De Carlo, F; Picetti, E; Reverberi, C; Rossi, I; Servadei, F, 2016) |
| "It was previously shown that sustained fever can be induced in rats by central injection of endothelin-1 (ET-1)." | 7.73 | The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats. ( Cristofoletti, R; Fabricio, AS; Navarra, P; Souza, GE; Veiga, FH, 2005) |
| "Therapeutic effect of sodium diclofenac during fever reaction is associated not only with specific modulation of thermoregulation, but also with the increase in the count of lymphocytes transported with the lymph into systemic circulation, stimulation of lymph microcirculation, and improvement of metabolism in the interstitial space." | 7.73 | Effect of sodium diclofenac on microcirculation and composition of the lymph during fever reaction. ( Mukhutdinova, FI; Tagirova, DR, 2005) |
| " Well documented safety and efficacy, a rapid onset of action and a flexible daily dosing regimen are essential in this context." | 6.44 | Diclofenac potassium 12.5mg tablets for mild to moderate pain and fever: a review of its pharmacology, clinical efficacy and safety. ( Moore, N, 2007) |
| "Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) advocated for use in painful and inflammatory rheumatic and certain non-rheumatic conditions." | 6.16 | Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. ( Sorkin, EM; Todd, PA, 1988) |
| "(1) Renal colic is an acute syndrome involving unilateral flank pain, linked to an obstruction in the upper urinary tract." | 5.35 | Renal colic in adults: NSAIDs and morphine are effective for pain relief. ( , 2009) |
| "Twenty-two febrile comatose patients: 12 severe traumatic brain injury and 10 subarachnoid hemorrhage divided in 2 groups: Diclofenac low-dose infusion (10 patients) and extemporaneous boluses of NSAIDs (CTRL, 12 patients)." | 5.12 | Continuous low dose diclofenac sodium infusion to control fever in neurosurgical critical care. ( Citerio, G; Cormio, M, 2007) |
| " The role of COX-2 in the genesis of fever in monkeys and humans was examined with use of the specific COX-2 inhibitor rofecoxib." | 5.09 | Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans. ( Adcock, S; Bachmann, KA; Chan, CC; Cohen, RA; Davidson, MH; Dobratz, D; Gertz, BJ; Grasing, K; Hedges, J; Jones, TM; McBride, KJ; Moritz, C; Mukhopadhyay, S; Schwartz, JI, 1999) |
| "We observed that a low-dose diclofenac sodium infusion was effective in treating fever without systemic side effects." | 5.01 | Continuous intravenous low-dose diclofenac sodium to control a central fever after ischemic stroke in the intensive care unit: a case report and review of the literature. ( Aurilio, C; Esposito, V; Giaccari, LG; Pace, MC; Passavanti, MB; Pota, V; Sansone, P, 2019) |
| "To evaluate the cerebral and hemodynamic effects of low-dose intramuscular diclofenac sodium (DCFS) administered for fever control in patients with acute brain injury in the intensive care unit." | 3.83 | Low-Dose Intramuscular Diclofenac Sodium for Fever Control in Acute Brain Injury. ( Antonini, MV; Caspani, ML; De Carlo, F; Picetti, E; Reverberi, C; Rossi, I; Servadei, F, 2016) |
| "It was previously shown that sustained fever can be induced in rats by central injection of endothelin-1 (ET-1)." | 3.73 | The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats. ( Cristofoletti, R; Fabricio, AS; Navarra, P; Souza, GE; Veiga, FH, 2005) |
| " Efficacy of lumiracoxib in rat models of hyperalgesia, oedema, pyresis and arthritis was dose-dependent and similar to diclofenac." | 3.73 | Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2. ( Berry, C; Dawson, J; Du, Z; Esser, R; Fox, A; Fujimoto, RA; Haston, W; Kimble, EF; Koehler, J; Marshall, PJ; Peppard, J; Quadros, E; Quintavalla, J; Toscano, K; Urban, L; van Duzer, J; Zhang, X; Zhou, S, 2005) |
| " Administration of diclofenac, a nonselective cyclooxygenase (COX) inhibitor, at different doses (5, 50, 500, or 5,000 microg/kg) attenuated or abrogated LPS-induced fever and inhibited LPS-induced local PGE(2) formation (5 or 500 microg/kg diclofenac)." | 3.73 | Localized vs. systemic inflammation in guinea pigs: a role for prostaglandins at distinct points of the fever induction pathways? ( Barth, SW; Gerstberger, R; Hübschle, T; Korte, S; Roth, J; Rummel, C; Voss, T, 2005) |
| "Therapeutic effect of sodium diclofenac during fever reaction is associated not only with specific modulation of thermoregulation, but also with the increase in the count of lymphocytes transported with the lymph into systemic circulation, stimulation of lymph microcirculation, and improvement of metabolism in the interstitial space." | 3.73 | Effect of sodium diclofenac on microcirculation and composition of the lymph during fever reaction. ( Mukhutdinova, FI; Tagirova, DR, 2005) |
| " The anti-inflammatory potency of NS-398 in rat carrageenin-induced edema was as potent as that of indomethacin and 8 times more potent than diclofenac." | 3.68 | NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. ( Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K, 1993) |
| " Two transcervical intra-uterine insertions of 216 mg of quinacrine, carried out at an interval of one month and associated with 50 mg of intra-uterine diclofenac and 150 mg of intra-muscular diclofenac resulted in a pregnancy rate after 12 months of 2." | 3.68 | [Non-surgical female sterilization using quinacrine: efficacy of two insertions of quinacrine pellets]. ( Rivera, M; Trujillo, V; Viel, B; Zipper, J, 1993) |
| "Diclofenac-K was superior to placebo (P < 0." | 2.71 | A multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled, parallel-group comparison of diclofenac-K and ibuprofen for the treatment of adults with influenza-like symptoms. ( Frank, WO; Gold, MS; Grebe, W; Ionescu, E; Liu, JM, 2003) |
| "Fever is a common symptom in cancer patients." | 2.70 | Symptomatic intravenous antipyretic therapy: efficacy of metamizol, diclofenac, and propacetamol. ( Korístek, Z; Mayer, J; Oborilová, A; Pospísil, Z, 2002) |
| "Paraneoplastic fever is well known, and is not an uncommon problem in daily practice." | 2.67 | A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever. ( Bacojanis, C; Beldecos, D; Karabelis, A; Karvounis, N; Kosmidis, P; Milonacis, N; Tsavaris, N; Zinelis, A, 1990) |
| " Well documented safety and efficacy, a rapid onset of action and a flexible daily dosing regimen are essential in this context." | 2.44 | Diclofenac potassium 12.5mg tablets for mild to moderate pain and fever: a review of its pharmacology, clinical efficacy and safety. ( Moore, N, 2007) |
| "Fever is common in patients with acute brain injury and worsens secondary brain injury and clinical outcomes." | 1.51 | A Survey on Fever Monitoring and Management in Patients With Acute Brain Injury: The SUMMA Study. ( Helbok, R; Oddo, M; Picetti, E; Prisco, L; Taccone, FS, 2019) |
| "(1) Renal colic is an acute syndrome involving unilateral flank pain, linked to an obstruction in the upper urinary tract." | 1.35 | Renal colic in adults: NSAIDs and morphine are effective for pain relief. ( , 2009) |
| "A patient with rheumatoid arthritis is described who presented with low-grade fever for 3 months, in whom Actinobacillus ureae was cultured from bone marrow aspirate." | 1.30 | Bone marrow infection caused by Actinobacillus ureae in a rheumatoid arthritis patient. ( Avlami, A; Dounis, E; Kordossis, T; Papalambrou, C; Tzivra, M, 1997) |
| "Diclofenac sodium proved to be a very potent antipyretic agent with serious side effects." | 1.27 | Antipyretic therapy with diclofenac sodium. Observations on effect and serious side effects in critically ill patients. ( Alexander, JP; Stoutenbeek, CP; Zandstra, DF, 1983) |
| " We conclude that the proposed dosage (in the selected patient population) constitutes effective antipyretic treatment devoid of major side effects." | 1.27 | Antipyretic therapy in ICU patients: evaluation of low dose diclofenac sodium. ( Basilico, E; Grossi, E; Pesenti, A; Riboni, A, 1986) |
Research
Studies (48)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (22.92) | 18.7374 |
| 1990's | 7 (14.58) | 18.2507 |
| 2000's | 24 (50.00) | 29.6817 |
| 2010's | 6 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Giaccari, LG | 1 |
| Pace, MC | 1 |
| Passavanti, MB | 1 |
| Sansone, P | 1 |
| Esposito, V | 1 |
| Aurilio, C | 1 |
| Pota, V | 1 |
| Schiefecker, AJ | 1 |
| Rass, V | 1 |
| Gaasch, M | 1 |
| Kofler, M | 1 |
| Thomé, C | 1 |
| Humpel, C | 1 |
| Ianosi, B | 1 |
| Hackl, WO | 1 |
| Beer, R | 1 |
| Pfausler, B | 1 |
| Schmutzhard, E | 1 |
| Helbok, R | 2 |
| Picetti, E | 2 |
| Oddo, M | 1 |
| Prisco, L | 1 |
| Taccone, FS | 1 |
| Polukonova, NV | 1 |
| Navolokin, NA | 1 |
| Raĭkova, SV | 1 |
| Masliakova, GN | 1 |
| Bucharskaia, AB | 1 |
| Durnova, NA | 1 |
| Shub, GM | 1 |
| Servadei, F | 1 |
| Reverberi, C | 1 |
| De Carlo, F | 1 |
| Rossi, I | 1 |
| Antonini, MV | 1 |
| Caspani, ML | 1 |
| Niazi, J | 1 |
| Singh, P | 1 |
| Bansal, Y | 1 |
| Goel, RK | 1 |
| Marais, M | 1 |
| Maloney, SK | 3 |
| Gray, DA | 3 |
| Ross, G | 2 |
| Hübschle, T | 4 |
| Pehl, U | 2 |
| Braun, HA | 1 |
| Voigt, K | 1 |
| Gerstberger, R | 4 |
| Roth, J | 4 |
| Oborilová, A | 1 |
| Mayer, J | 1 |
| Pospísil, Z | 1 |
| Korístek, Z | 1 |
| Dogan, MD | 1 |
| Ataoglu, H | 1 |
| Akarsu, ES | 1 |
| Grebe, W | 1 |
| Ionescu, E | 1 |
| Gold, MS | 1 |
| Liu, JM | 1 |
| Frank, WO | 1 |
| Aleksandrov, PN | 1 |
| Mukhutdinova, FI | 2 |
| Tagirova, DR | 2 |
| Mukhutdinov, DA | 1 |
| Caricato, A | 1 |
| Conti, G | 1 |
| Mercurio, G | 1 |
| Mancino, A | 1 |
| Santilli, F | 1 |
| Antonelli, M | 1 |
| Proietti, R | 1 |
| Fabricio, AS | 1 |
| Veiga, FH | 1 |
| Cristofoletti, R | 1 |
| Navarra, P | 1 |
| Souza, GE | 1 |
| Esser, R | 1 |
| Berry, C | 1 |
| Du, Z | 1 |
| Dawson, J | 1 |
| Fox, A | 1 |
| Fujimoto, RA | 1 |
| Haston, W | 1 |
| Kimble, EF | 1 |
| Koehler, J | 1 |
| Peppard, J | 1 |
| Quadros, E | 1 |
| Quintavalla, J | 1 |
| Toscano, K | 1 |
| Urban, L | 1 |
| van Duzer, J | 1 |
| Zhang, X | 1 |
| Zhou, S | 1 |
| Marshall, PJ | 1 |
| Rummel, C | 1 |
| Barth, SW | 1 |
| Voss, T | 1 |
| Korte, S | 1 |
| Kamerman, PR | 2 |
| Okumura, A | 1 |
| Fukumoto, Y | 1 |
| Hayakawa, F | 1 |
| Nakano, T | 1 |
| Higuchi, K | 1 |
| Kamiya, H | 1 |
| Watanabe, K | 1 |
| Morishima, T | 1 |
| Rüster, M | 1 |
| Kiehntopf, M | 1 |
| Gröne, HJ | 1 |
| Wolf, G | 1 |
| Daud, A | 1 |
| Habib, N | 1 |
| Riera, AS | 1 |
| Moore, N | 1 |
| Greis, A | 1 |
| Murgott, J | 1 |
| Rafalzik, S | 1 |
| Greer, DM | 1 |
| Cormio, M | 2 |
| Citerio, G | 2 |
| Zandstra, DF | 2 |
| Stoutenbeek, CP | 2 |
| Alexander, JP | 1 |
| Dittmer, A | 1 |
| Polman, HA | 1 |
| Huijbers, WA | 1 |
| Augusteijn, R | 1 |
| Futaki, N | 1 |
| Yoshikawa, K | 1 |
| Hamasaka, Y | 1 |
| Arai, I | 1 |
| Higuchi, S | 1 |
| Iizuka, H | 1 |
| Otomo, S | 1 |
| Trujillo, V | 1 |
| Zipper, J | 1 |
| Viel, B | 1 |
| Rivera, M | 1 |
| Avlami, A | 1 |
| Papalambrou, C | 1 |
| Tzivra, M | 1 |
| Dounis, E | 1 |
| Kordossis, T | 1 |
| Kido, H | 1 |
| Murakami, N | 1 |
| Ito, A | 1 |
| Kimura, K | 1 |
| Kodera, N | 1 |
| Doi, T | 1 |
| Naruse, T | 1 |
| Schwartz, JI | 1 |
| Chan, CC | 1 |
| Mukhopadhyay, S | 1 |
| McBride, KJ | 1 |
| Jones, TM | 1 |
| Adcock, S | 1 |
| Moritz, C | 1 |
| Hedges, J | 1 |
| Grasing, K | 1 |
| Dobratz, D | 1 |
| Cohen, RA | 1 |
| Davidson, MH | 1 |
| Bachmann, KA | 1 |
| Gertz, BJ | 1 |
| Enrique, E | 1 |
| Cisteró-Bahima, A | 1 |
| Alonso, R | 1 |
| Bravo, P | 1 |
| Fenollosa, A | 1 |
| Torre, I | 1 |
| Spear, S | 1 |
| Fumagalli, R | 1 |
| Pesenti, A | 2 |
| Tsavaris, N | 1 |
| Zinelis, A | 1 |
| Karabelis, A | 1 |
| Beldecos, D | 1 |
| Bacojanis, C | 1 |
| Milonacis, N | 1 |
| Karvounis, N | 1 |
| Kosmidis, P | 1 |
| McGalliard, J | 1 |
| Bell, AL | 1 |
| Cedrato, AE | 1 |
| Passarelli, I | 1 |
| Cimollini, L | 1 |
| Maccarone, H | 1 |
| Scholer, DW | 2 |
| Ku, EC | 2 |
| Boettcher, I | 2 |
| Schweizer, A | 2 |
| Todd, PA | 1 |
| Sorkin, EM | 1 |
| Bettini, R | 1 |
| Grossi, E | 2 |
| Rapazzini, P | 1 |
| Giardina, G | 1 |
| Riboni, A | 1 |
| Basilico, E | 1 |
| Wouters, JM | 1 |
| van Rijswijk, MH | 1 |
| van de Putte, LB | 1 |
Reviews
4 reviews available for diclofenac and Fever
| Article | Year |
|---|---|
Continuous intravenous low-dose diclofenac sodium to control a central fever after ischemic stroke in the intensive care unit: a case report and review of the literature.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Diclofenac; Female; Fever; Humans; In | 2019 |
Diclofenac potassium 12.5mg tablets for mild to moderate pain and fever: a review of its pharmacology, clinical efficacy and safety.
Topics: Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Fever; Humans; Molecular St | 2007 |
[Body temperature and fever--body temperature regulation, indications and possibilities of fever reducing therapy. II. Indications and effects of fever-lowering procedures and fever-reducing drug therapy].
Topics: Acetaminophen; Age Factors; Aminopyrine; Body Temperature Regulation; Child; Child, Preschool; Diclo | 1981 |
Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; D | 1988 |
Trials
10 trials available for diclofenac and Fever
| Article | Year |
|---|---|
Symptomatic intravenous antipyretic therapy: efficacy of metamizol, diclofenac, and propacetamol.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammato | 2002 |
A multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled, parallel-group comparison of diclofenac-K and ibuprofen for the treatment of adults with influenza-like symptoms.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Administration | 2003 |
Continuous low dose diclofenac sodium infusion to control fever in neurosurgical critical care.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Brain Injuries; Critical Care; | 2007 |
The use of diclofenac sodium (Voltaren) suppositories as an antipyretic in children with fever due to acute infections: a double-blind, between-patient, placebo-controlled study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacterial Infections; Child; Child, Preschool; Clinical Tri | 1981 |
Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans.
Topics: Administration, Oral; Analysis of Variance; Animals; Body Temperature; Cyclooxygenase 2; Cyclooxygen | 1999 |
Diclofenac-induced fever.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Chlorpheniramine; Diclofenac; Drug Hypers | 2000 |
A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Fever; Humans; Indomethacin; Male; Napr | 1990 |
[Comparison of the antipyretic effect of a single dose of dipyrone, paracetamol and diclofenac resinate. A multicenter clinical trial].
Topics: Acetaminophen; Body Temperature; Child; Child, Preschool; Diclofenac; Dipyrone; Female; Fever; Human | 1989 |
Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Clinical Trials as Topic; Diclofenac; D | 1988 |
Diclofenac sodium versus acetylsalicylic acid: a randomized study in febrile patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diclofenac; Drug | 1986 |
Other Studies
35 other studies available for diclofenac and Fever
| Article | Year |
|---|---|
Brain Extracellular Interleukin-6 Levels Decrease Following Antipyretic Therapy with Diclofenac in Patients with Spontaneous Subarachnoid Hemorrhage.
Topics: Aged; Antipyretics; Body Temperature; Brain Chemistry; Dialysis; Diclofenac; Extracellular Space; Fe | 2019 |
A Survey on Fever Monitoring and Management in Patients With Acute Brain Injury: The SUMMA Study.
Topics: Acetaminophen; Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Body Tem | 2019 |
[AntI-inflammatory, antipyretic and antimicrobial activity of flavonoid-containing extract of Gratiola officinalis L].
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antipyretics; Diclofenac; Edema; Fever; Fl | 2015 |
Low-Dose Intramuscular Diclofenac Sodium for Fever Control in Acute Brain Injury.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Diclofenac; Female; Fever; Humans; I | 2016 |
Anti-inflammatory, analgesic and antipyretic activity of aqueous extract of fresh leaves of Coccinia indica.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Cucurbitacea | 2009 |
Renal colic in adults: NSAIDs and morphine are effective for pain relief.
Topics: Acetaminophen; Adult; Analgesia; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clinic | 2009 |
Brain IL-6- and PG-dependent actions of IL-1β and lipopolysaccharide in avian fever.
Topics: Analysis of Variance; Animals; Antibodies; Body Temperature Regulation; Brain; Cyclooxygenase Inhibi | 2011 |
Fever induction by localized subcutaneous inflammation in guinea pigs: the role of cytokines and prostaglandins.
Topics: Animals; Carrier Proteins; Cyclooxygenase Inhibitors; Cytokines; Diclofenac; Drug Combinations; Drug | 2003 |
Nimesulide and diclofenac inhibit lipopolysaccharide-induced hypothermia and tumour necrosis factor-alpha elevation in rats.
Topics: Analysis of Variance; Animals; Body Temperature Regulation; Cyclooxygenase 2; Cyclooxygenase 2 Inhib | 2002 |
Effect of orthophen on microlymphocirculation during fever reaction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Fever; Lymph; Lymphatic System | 2004 |
Continuous low-dose diclofenac infusion for fever control in patients with acute neurological lesions.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Temperature; Cerebrovascular Circulati | 2004 |
The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Dose-Response Re | 2005 |
Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Biological Availability; | 2005 |
Localized vs. systemic inflammation in guinea pigs: a role for prostaglandins at distinct points of the fever induction pathways?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibito | 2005 |
Effect of sodium diclofenac on microcirculation and composition of the lymph during fever reaction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Fever; Kallikreins; Kinins; Ly | 2005 |
Lipopolysaccharide-induced fever in Pekin ducks is mediated by prostaglandins and nitric oxide and modulated by adrenocortical hormones.
Topics: Animals; Anti-Inflammatory Agents; Corticosterone; Dexamethasone; Diclofenac; Ducks; Enzyme Inhibito | 2005 |
Antipyretics and delirious behavior during febrile illness.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Delirium; Diclofenac; | 2006 |
A Friday afternoon case of apparent anti-glomerular basement nephritis.
Topics: Acetaminophen; Acute Kidney Injury; Analgesics; Animals; Anti-Glomerular Basement Membrane Disease; | 2006 |
Anti-inflammatory, anti-nociceptive and antipyretic effects of extracts of Phrygilanthus acutifolius flowers.
Topics: Acetic Acid; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non- | 2006 |
Characterization of the febrile response induced by fibroblast-stimulating lipopeptide-1 in guinea pigs.
Topics: Animals; Body Temperature; Cyclooxygenase Inhibitors; Cytokines; Diclofenac; Diglycerides; Dinoprost | 2007 |
Continuous intravenous NSAID administration for fever control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Critical Care; Diclofenac; Fever; Humans; I | 2007 |
Restraint increases afebrile body temperature but attenuates fever in Pekin ducks (Anas platyrhynchos).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Body Temperature Regulation; Dic | 2008 |
Antipyretic therapy with diclofenac sodium. Observations on effect and serious side effects in critically ill patients.
Topics: Acute Disease; Body Temperature; Critical Care; Diclofenac; Fever; Humans; Oliguria; Phenylacetates; | 1983 |
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygena | 1993 |
[Non-surgical female sterilization using quinacrine: efficacy of two insertions of quinacrine pellets].
Topics: Adult; Diclofenac; Drug Implants; Female; Fever; Headache; Humans; Injections, Intramuscular; Metror | 1993 |
Bone marrow infection caused by Actinobacillus ureae in a rheumatoid arthritis patient.
Topics: Actinobacillus; Actinobacillus Infections; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, | 1997 |
Anti-inflammatory, analgesic and anti-pyretic effects of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a new non-steroidal anti-inflammatory drug, in rats and guinea pigs.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 1998 |
Control of fever by continuous, low-dose diclofenac sodium infusion in acute cerebral damage patients.
Topics: Acute Disease; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Craniocerebral | 2000 |
Influence of systemic treatment with cyclooxygenase inhibitors on lipopolysaccharide-induced fever and circulating levels of cytokines and cortisol in guinea-pigs.
Topics: Animals; Body Temperature Regulation; Cyclooxygenase Inhibitors; Diclofenac; Fever; Guinea Pigs; Hyd | 2002 |
Acquired Brown's syndrome in systemic lupus erythematosus: another ocular manifestation.
Topics: Adult; Diclofenac; Diplopia; Fever; Humans; Hydroxychloroquine; Ibuprofen; Lupus Erythematosus, Syst | 1990 |
Pharmacology of diclofenac sodium.
Topics: Analgesics; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diclofenac; Dos | 1986 |
Antipyretic therapy in intensive care.
Topics: Critical Care; Diclofenac; Fever; Humans; Respiration, Artificial | 1987 |
Antipyretic therapy in ICU patients: evaluation of low dose diclofenac sodium.
Topics: Body Temperature; Critical Care; Diclofenac; Drug Evaluation; Fever; Hemodynamics; Humans; Kidney; O | 1986 |
Pharmacology of diclofenac sodium (Voltaren).
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimental; Cyclooxygenase Inhibitors; Di | 1985 |
Adult onset Still's disease in the elderly: a report of two cases.
Topics: Aged; Arthritis; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Diagnosis, Differentia | 1985 |