| Assay ID | Title | Year | Journal | Article |
|---|
| AID655753 | Volume of distribution at steady state in cynomolgus monkey at 3 mg/kg, iv | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655738 | Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP release after 45 mins | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655749 | Half life in beagle dog at 10 mg/kg, po | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655752 | Volume of distribution at steady state in beagle dog at 3 mg/kg, iv | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655754 | Oral bioavailability in rat at 10 mg/kg | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655756 | Oral bioavailability in cynomolgus monkey at 10 mg/kg | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID1638013 | Agonist activity at human CB2 receptor | 2019 | European journal of medicinal chemistry, Mar-01, Volume: 165 | Benzo[d]thiazol-2(3H)-ones as new potent selective CB |
| AID655751 | Volume of distribution at steady state in rat at 3 mg/kg, iv | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655736 | Displacement of [3H]-CP55940 from human recombinant CB2 receptor after 60 mins | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID1127545 | Agonist activity at CB2 receptor (unknown origin) | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists. |
| AID1638014 | Agonist activity at human CB1 receptor | 2019 | European journal of medicinal chemistry, Mar-01, Volume: 165 | Benzo[d]thiazol-2(3H)-ones as new potent selective CB |
| AID655745 | Clearance in rat at 3 mg/kg, iv | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655735 | Displacement of [3H]-CP55940 from human recombinant CB1 receptor after 60 mins | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655747 | Clearance in cynomolgus monkey at 3 mg/kg, iv | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655743 | Antipruritic activity in ICR mouse assessed as inhibition of compound 48/80-induced scratching at 3 mg/kg, po measured after 30 mins | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655755 | Oral bioavailability in beagle dog at 10 mg/kg | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655742 | Antipruritic activity in ICR mouse assessed as inhibition of compound 48/80-induced scratching at 1 mg/kg, po measured after 30 mins | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655744 | Antipruritic activity in ICR mouse assessed as inhibition of compound 48/80-induced scratching at 10 mg/kg, po measured after 30 mins | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655748 | Half life in rat at 10 mg/kg, po | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID1127546 | Agonist activity at CB1 receptor (unknown origin) | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists. |
| AID655746 | Clearance in beagle dog at 3 mg/kg, iv | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655750 | Half life in cynomolgus monkey at 10 mg/kg, po | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655739 | Selectivity ratio of Ki for human CB1 receptor to Ki for human CB2 receptor | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| AID655737 | Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP release after 25 mins | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |