Page last updated: 2024-10-16

acetone and Pruritus

acetone has been researched along with Pruritus in 18 studies

methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).

Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.

Research Excerpts

ExcerptRelevanceReference
"Dry skin-induced chronic itching was created by topical application of AEW (acetone/diethyl ether/water)."4.12The Effects of Cannabinoid Agonist, Heat Shock Protein 90 and Nitric Oxide Synthase Inhibitors on Increasing IL-13 and IL-31 Levels in Chronic Pruritus. ( Çakır Gündoğdu, A; Özyazgan, S; Ozyurt, R; Todurga Seven, ZG, 2022)
" An acetone-ether-water (AEW) model as a histamine-independent itch model is often used in the study of chronic pruritus."3.85MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model. ( Geng, X; Gu, L; Hu, D; Lan, L; Shi, H; Tang, Z; Wang, C; Wu, G; Yang, N; Yang, Y; Yu, G; Yu, L; Yuan, X; Zhu, C, 2017)
"To develop a behavioral model in mice that is capable of mimicking some distinctive symptoms of human posttraumatic trigeminal neuropathic pain such as spontaneous pain, cold allodynia, and chemical÷inflammatory hyperalgesia, and to use this model to investigate the antinociceptive effects of clomipramine and tramadol, two drugs used for the treatment of neuropathic pain."3.77Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice. ( Alvarez, P; Brun, A; Constandil, L; Correa, A; Hernández, A; Labertrandie, A; Lopez, J; Pelissier, T, 2011)
"Repeated application of 1% 2,4,6-trinitrochlorobenzene (TNCB) in acetone solution causes chronic skin inflammation in BALB/c mice."3.73Dermal mast cells play a central role in the incidence of scratching behavior in mice induced by multiple application of the hapten, 2,4,6-trinitrochlorobenzene. ( Michibata, Y; Mizukami, H; Morita, A; Nose, M; Ogihara, Y; Yamashita, H, 2005)
"As a model of dry skin pruritus in mice, one hind paw was treated twice daily with a mixture of acetone/diethylether/water (AEW); controls received water only."3.72Spinal c-fos expression associated with spontaneous biting in a mouse model of dry skin pruritus. ( Carstens, E; Carstens, MI; Cuellar, JM; Nojima, H; Simons, CT, 2004)
"Chronic itch (pruritus) is an important clinical problem."1.43Enhanced itch elicited by capsaicin in a chronic itch model. ( Chen, M; Gegen, T; Guo, CJ; He, Q; Hu, D; Li, F; Liu, Q; Shi, H; Tang, M; Tang, Z; Wang, C; Wang, Z; Yang, N; Yang, Y; Yu, G; Zhu, C, 2016)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (11.11)29.6817
2010's14 (77.78)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Todurga Seven, ZG1
Çakır Gündoğdu, A1
Ozyurt, R1
Özyazgan, S1
Fan, JJ1
Gao, B1
Song, AQ1
Zhu, YJ1
Zhou, J1
Li, WZ1
Yin, YY1
Wu, WN1
Cao, LF1
Si, M1
Huang, Y1
Chen, LH1
Peng, XY1
Qin, YQ1
Liu, TT1
Zhou, Y1
Liu, T1
Luo, WF1
Shi, H2
Yu, G2
Geng, X1
Gu, L1
Yang, N2
Wang, C2
Zhu, C2
Yang, Y2
Yu, L1
Hu, D2
Yuan, X1
Lan, L1
Wu, G1
Tang, Z2
Zhao, X1
Yu, C1
Ye, F1
Wang, YG1
Mei, QY1
Ma, Q1
Cui, WG1
Zhou, WH1
Iwanaga, T1
Tominaga, M3
Hirata, Y1
Matsuda, H1
Shimanuki, T1
Ogawa, H3
Takamori, K3
Kamo, A2
Taneda, K1
Schüttenhelm, BN1
Duraku, LS1
Dijkstra, JF1
Walbeehm, ET1
Holstege, JC1
Barcelos, RC1
de Mello-Sampayo, C1
Antoniazzi, CT1
Segat, HJ1
Silva, H1
Veit, JC1
Piccolo, J1
Emanuelli, T1
Bürger, ME1
Silva-Lima, B1
Rodrigues, LM1
Li, F1
Chen, M1
Guo, CJ1
Wang, Z1
Gegen, T1
Tang, M1
He, Q1
Liu, Q1
Ono, R1
Kagawa, Y1
Takahashi, Y1
Akagi, M1
Kamei, C1
Negi, O1
Tengara, S1
Akiyama, T1
Carstens, MI2
Carstens, E2
Alvarez, P1
Brun, A1
Labertrandie, A1
Lopez, J1
Correa, A1
Constandil, L1
Hernández, A1
Pelissier, T1
Okawa, T1
Yamaguchi, Y1
Takada, S1
Sakai, Y1
Numata, N1
Nakamura, F1
Nagashima, Y1
Ikezawa, Z1
Aihara, M1
Yamamoto-Kasai, E1
Imura, K1
Yasui, K1
Shichijou, M1
Oshima, I1
Hirasawa, T1
Sakata, T1
Yoshioka, T1
Nojima, H1
Cuellar, JM1
Simons, CT1
Yamashita, H1
Michibata, Y1
Mizukami, H1
Ogihara, Y1
Morita, A1
Nose, M1

Other Studies

18 other studies available for acetone and Pruritus

ArticleYear
The Effects of Cannabinoid Agonist, Heat Shock Protein 90 and Nitric Oxide Synthase Inhibitors on Increasing IL-13 and IL-31 Levels in Chronic Pruritus.
    Immunological investigations, 2022, Volume: 51, Issue:7

    Topics: Acetone; Animals; Antipruritics; Benzoquinones; Benzoxazines; Cannabinoid Receptor Agonists; Cannabi

2022
Spinal cord NLRP1 inflammasome contributes to dry skin induced chronic itch in mice.
    Journal of neuroinflammation, 2020, Apr-20, Volume: 17, Issue:1

    Topics: Acetone; Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; Chronic Disea

2020
Long-term anti-itch effect of botulinum neurotoxin A is associated with downregulation of TRPV1 and TRPA1 in the dorsal root ganglia in mice.
    Neuroreport, 2017, Jun-14, Volume: 28, Issue:9

    Topics: Acetone; Animals; Botulinum Toxins, Type A; Chloroquine; Chronic Disease; Disease Models, Animal; Do

2017
MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model.
    Neuroreport, 2017, Dec-06, Volume: 28, Issue:17

    Topics: Acetone; Animals; Calcium; Cations, Divalent; Cells, Cultured; Chloroquine; Chronic Disease; Disease

2017
Chronic itch impairs mood and HPA axis function in mice: modulation by CRFR1 antagonist.
    Pain, 2018, Volume: 159, Issue:11

    Topics: Acetone; Adaptation, Ocular; Animals; Disease Models, Animal; Diterpenes; Feeding Behavior; Fever; F

2018
Effects of Film Dressings on Itch Hypersensitivity Using Murine Dry Skin Models.
    Acta dermato-venereologica, 2018, Oct-10, Volume: 98, Issue:9

    Topics: Acetone; Animals; Bandages; Dermatitis, Atopic; Disease Models, Animal; Epidermis; Ether; Male; Mice

2018
Neurotropin inhibits the increase in intraepidermal nerve density in the acetone-treated dry-skin mouse model.
    Clinical and experimental dermatology, 2013, Volume: 38, Issue:6

    Topics: Acetone; Animals; Disease Models, Animal; Epidermis; Male; Mice; Mice, Inbred ICR; Nerve Growth Fact

2013
Differential Changes in the Peptidergic and the Non-Peptidergic Skin Innervation in Rat Models for Inflammation, Dry Skin Itch, and Dermatitis.
    The Journal of investigative dermatology, 2015, Volume: 135, Issue:8

    Topics: Acetone; Animals; Biopsy; Calcitonin Gene-Related Peptide; Dermatitis; Dinitrochlorobenzene; Disease

2015
Oral supplementation with fish oil reduces dryness and pruritus in the acetone-induced dry skin rat model.
    Journal of dermatological science, 2015, Volume: 79, Issue:3

    Topics: Acetone; Administration, Oral; Animals; Behavior, Animal; Dietary Supplements; Disease Models, Anima

2015
Enhanced itch elicited by capsaicin in a chronic itch model.
    Molecular pain, 2016, Volume: 12

    Topics: Acetone; Animals; Behavior, Animal; Capsaicin; Chronic Disease; Disease Models, Animal; Ether; Femal

2016
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on scratching behavior in mice.
    International immunopharmacology, 2010, Volume: 10, Issue:3

    Topics: Acetone; Animals; Antipruritics; Behavior, Animal; Environmental Pollutants; Histamine H1 Antagonist

2010
Topical application of emollients prevents dry skin-inducible intraepidermal nerve growth in acetone-treated mice.
    Journal of dermatological science, 2011, Volume: 62, Issue:1

    Topics: Acetone; Administration, Topical; Animals; Emollients; Heparinoids; Male; Mice; Mice, Inbred ICR; Mo

2011
Enhanced responses of lumbar superficial dorsal horn neurons to intradermal PAR-2 agonist but not histamine in a mouse hindpaw dry skin itch model.
    Journal of neurophysiology, 2011, Volume: 105, Issue:6

    Topics: Acetone; Action Potentials; Analysis of Variance; Animals; Antipruritics; Capsaicin; Disease Models,

2011
Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice.
    Journal of orofacial pain, 2011,Fall, Volume: 25, Issue:4

    Topics: Acetone; Analgesics, Opioid; Animals; Capsaicin; Clomipramine; Disease Models, Animal; Formaldehyde;

2011
Oral administration of collagen tripeptide improves dryness and pruritus in the acetone-induced dry skin model.
    Journal of dermatological science, 2012, Volume: 66, Issue:2

    Topics: Acetone; Administration, Oral; Animals; Cells, Cultured; Collagen Type I; Dermatologic Agents; Human

2012
TRPV3 as a therapeutic target for itch.
    The Journal of investigative dermatology, 2012, Volume: 132, Issue:8

    Topics: Acetone; Animals; Dermatitis, Atopic; Ether; Humans; Mice; Mice, Inbred ICR; Mice, Transgenic; Pruri

2012
Spinal c-fos expression associated with spontaneous biting in a mouse model of dry skin pruritus.
    Neuroscience letters, 2004, May-06, Volume: 361, Issue:1-3

    Topics: Acetone; Afferent Pathways; Animals; Dermatitis, Atopic; Disease Models, Animal; Ether; Functional L

2004
Dermal mast cells play a central role in the incidence of scratching behavior in mice induced by multiple application of the hapten, 2,4,6-trinitrochlorobenzene.
    Experimental dermatology, 2005, Volume: 14, Issue:6

    Topics: Acetone; Animals; Female; Genotype; Haptens; Immunoglobulin E; Inflammation; Male; Mast Cells; Mice;

2005