chlorambucil has been researched along with Pruritus in 10 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Multicentric histiocytosis is a rare systemic disease with active episodes and prolonged periods of remission." | 1.29 | [Multicenter histiocytosis]. ( Bazex, J; Gorguet, B; Grolleau-Rochiccioli, P; Laplanche, G; Manzur, F; Schmitt, AM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Schmitt, AM | 1 |
| Grolleau-Rochiccioli, P | 1 |
| Laplanche, G | 1 |
| Gorguet, B | 1 |
| Manzur, F | 1 |
| Bazex, J | 1 |
| Hoffman, R | 1 |
| Wasserman, LR | 2 |
| Adams, D | 1 |
| Clements, D | 1 |
| Elias, E | 1 |
| Berk, PD | 1 |
| Goldberg, JD | 1 |
| Donovan, PB | 1 |
| Fruchtman, SM | 1 |
| Berlin, NI | 1 |
| Warnes, TW | 1 |
| Durepaire, R | 1 |
| Eisenmann, D | 1 |
| Grupper, C | 1 |
| Winkelmann, RK | 1 |
| Perry, HO | 1 |
| Muller, SA | 1 |
| Schroeter, AL | 1 |
| Jordon, RE | 1 |
| Rogers, RS | 1 |
| Libre, EP | 1 |
| Cuni, LJ | 1 |
| Grünwald, H | 1 |
| Rosner, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicenter Phase 2 Study of Efficacy and Safety of Pegylated Interferon-alfa 2a in Polycythemia Vera Patients[NCT00241241] | Phase 2 | 40 participants | Interventional | 2004-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for chlorambucil and Pruritus
| Article | Year |
|---|---|
Natural history and management of polycythemia vera.
Topics: Acute Disease; Adult; Antineoplastic Agents; Bloodletting; Cell Transformation, Neoplastic; Chloramb | 1979 |
The treatment of primary biliary cirrhosis.
Topics: Adrenal Cortex Hormones; Antipruritics; Azathioprine; Celiac Disease; Chlorambucil; Colchicine; Cycl | 1986 |
Treatment of primary biliary cirrhosis.
Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Chlorambucil; Cholelithiasis; Colchicine | 1985 |
1 trial available for chlorambucil and Pruritus
| Article | Year |
|---|---|
Therapeutic recommendations in polycythemia vera based on Polycythemia Vera Study Group protocols.
Topics: Acute Disease; Age Factors; Bloodletting; Chlorambucil; Combined Modality Therapy; False Positive Re | 1986 |
6 other studies available for chlorambucil and Pruritus
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
[Multicenter histiocytosis].
Topics: Adult; Arthritis; Chemical and Drug Induced Liver Injury; Chlorambucil; Cyclophosphamide; Histiocyto | 1994 |
[Malignant reticulosis with Sezary's cells and psoriasis].
Topics: Aged; Chlorambucil; Dermatitis, Exfoliative; Diagnosis, Differential; Edema; Foot Dermatoses; Hand D | 1971 |
Treatment of Sezary syndrome.
Topics: Chlorambucil; Cyclophosphamide; Dermatitis, Exfoliative; Humans; Keratoderma, Palmoplantar; Lymphati | 1974 |
Polycythemia: a disease of all ages.
Topics: Adult; Aged; Alkaline Phosphatase; Blood Platelets; Blood Volume; Bone Marrow; Chlorambucil; Erythro | 1974 |
Bullous pemphigoid in chronic lymphocytic leukemia with the demonstration of antibasement membrane antibodies.
Topics: Autoantibodies; Basement Membrane; Bilirubin; Biopsy; Blood Glucose; Blood Urea Nitrogen; Chlorambuc | 1974 |