brobenzoxaldine, broxyquinoline drug combination profile

brobenzoxaldine, broxyquinoline drug combination: mixture of broxyquinoline & brobenzoxaldine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	165685
MeSH ID	M0041668

Synonym
8060-82-0
intestopan
5,7-dibromo-2-methyl-8-quinolinol benzoate (ester) mixt. with 5,7-dibromo-8-quinolinol
enteroquin
brobenzoxaldine - broxyquinoline
brobenzoxaldine, broxyquinoline drug combination
broxaldine / broxyquinoline
brobenzoxaldine / broxyquinoline
DTXSID401001340
5,7-dibromo-2-methylquinolin-8-yl benzoate--5,7-dibromoquinolin-8-ol (1/1)
(5,7-dibromo-2-methylquinolin-8-yl) benzoate;5,7-dibromoquinolin-8-ol

Excerpt	Reference	Relevance
" Adverse effects were mild and did not affect treatment."	( A study on the neurotoxicity of broxyquinoline and brobenzoxaldine combination in therapeutic doses. Bapna, JS; Bosco, B; Chandrasekar, S; Das, AK; Swain, R; Swaminathan, RP; Thombre, DP; Veliath, S, 1986)	0.27

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	12 (92.31)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (7.69)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	1 (7.14%)	4.05%
Observational	0 (0.00%)	0.25%
Other	13 (92.86%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
oxyquinoline Oxyquinoline: An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.. quinolin-8-ol : A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.	3.89	13	monohydroxyquinoline	antibacterial agent; antifungal agrochemical; antiseptic drug; iron chelator
clioquinol Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.. 5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.	1.96	1	monohydroxyquinoline; organochlorine compound; organoiodine compound	antibacterial agent; antifungal agent; antimicrobial agent; antineoplastic agent; antiprotozoal drug; chelator; copper chelator
glutamine Glutamine: A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.. L-glutamine : An optically active form of glutamine having L-configuration.. glutamine : An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4.	2.05	1	amino acid zwitterion; glutamine family amino acid; glutamine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
decamethoxine decamethoxine: structure	1.96	1	quaternary ammonium salt
amphotericin b Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.. amphotericin B : A macrolide antibiotic used to treat potentially life-threatening fungal infections.	1.96	1	antibiotic antifungal drug; macrolide antibiotic; polyene antibiotic	antiamoebic agent; antiprotozoal drug; bacterial metabolite
candicidin Candicidin: Mixture of antifungal heptaene macrolides from Streptomyces griseus or Actinomyces levoris used topically in candidiasis. The antibiotic complex is composed of candicidins A, B, C, and D, of which D is the major component.. candicidin D : A 38-membered ring lactone containing seven (E)-double bonds between positions 22 and 35 and substituted by hydroxy groups at positions 9, 11, 13, 17 and 19, oxo groups at positions 3, 7 and 15, a carboxy group at position 18, a 3-amino-3,6-dideoxymannopyranosyloxy group at position 21, a methyl group at position 36 and a 7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl group at position 37. It is the major component of candicidin, a mixture of antifungal heptaene macrolides obtained from a strain of Streptomyces griseus.. candicidin : A mixture of the antifungal heptaene macrolides obtained from a strain of Streptomyces griseus. It is composed of candicidins A, B, C and D, with candicidin D being the major component. Candicidin is active against some fungi of the genus Candida, and has been used in the treatment of vaginal candidiasis.	1.96	1	macrolide antibiotic; polyene antibiotic	antifungal drug; bacterial metabolite
chiniofon Hydroxyquinolines: The 8-hydroxy derivatives inhibit various enzymes and their halogenated derivatives, though neurotoxic, are used as topical anti-infective agents, among other uses.	2.88	4
dicumarol Dicumarol: An oral anticoagulant that interferes with the metabolism of vitamin K. It is also used in biochemical experiments as an inhibitor of reductases.	1.94	1	hydroxycoumarin	anticoagulant; EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor; Hsp90 inhibitor; vitamin K antagonist

Condition	Relationship Strength	Studies
Complication, Postoperative [description not available]	2.05	1
Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	2.05	1
Dysentery Acute inflammation of the intestine associated with infectious DIARRHEA of various etiologies, generally acquired by eating contaminated food containing TOXINS, BIOLOGICAL derived from BACTERIA or other microorganisms. Dysentery is characterized initially by watery FECES then by bloody mucoid stools. It is often associated with ABDOMINAL PAIN; FEVER; and DEHYDRATION.	2.85	4
Giardia duodenalis Infection [description not available]	2.34	2
Amebiasis, Intestinal [description not available]	2.86	4
Giardiasis An infection of the SMALL INTESTINE caused by the flagellated protozoan GIARDIA. It is spread via contaminated food and water and by direct person-to-person contact.	2.34	2
Infections, Trichomonas [description not available]	1.93	1
Trichomonas Infections Infections in birds and mammals produced by various species of Trichomonas.	1.93	1
Abscess, Amebic [description not available]	1.94	1
E coli Infections [description not available]	1.94	1
Amebiasis Infection with any of various amebae. It is an asymptomatic carrier state in most individuals, but diseases ranging from chronic, mild diarrhea to fulminant dysentery may occur.	1.94	1
Diarrhea An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.	1.94	1
Escherichia coli Infections Infections with bacteria of the species ESCHERICHIA COLI.	1.94	1
Colitis Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.	2.35	2
Cholera Infantum [description not available]	1.95	1
Colitis Gravis [description not available]	1.96	1
Colitis, Ulcerative Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.	1.96	1
Pyrosis [description not available]	1.96	1
Nervous System Disorders [description not available]	1.96	1
Dysesthesia [description not available]	1.96	1
Itching [description not available]	1.96	1
Heartburn Substernal pain or burning sensation, usually associated with regurgitation of gastric juice into the esophagus.	1.96	1
Nausea An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.	1.96	1
Nervous System Diseases Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.	1.96	1
Pruritus An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.	1.96	1
Lassitude [description not available]	1.96	1
Fatigue The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.	1.96	1

brobenzoxaldine, broxyquinoline drug combination

Description

Cross-References

Synonyms (11)

Research Excerpts

Toxicity

Research

Studies (13)

Market Indicators

Research Demand Index: 11.43

Study Types

brobenzoxaldine, broxyquinoline drug combination

Description

Cross-References

Synonyms (11)

Research Excerpts

Toxicity

Research

Studies (13)

Market Indicators

Research Demand Index: 11.43

Study Types

Related Drugs (8)

Related Conditions (27)