| Assay ID | Title | Year | Journal | Article |
|---|
| AID588349 | qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay | | | |
| AID1347151 | Optimization of GU AMC qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347058 | CD47-SIRPalpha protein protein interaction - HTRF assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1347410 | qHTS for inhibitors of adenylyl cyclases using a fission yeast platform: a pilot screen against the NCATS LOPAC library | 2019 | Cellular signalling, 08, Volume: 60 | A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID588378 | qHTS for Inhibitors of ATXN expression: Validation | | | |
| AID504836 | Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation | 2002 | The Journal of biological chemistry, Apr-19, Volume: 277, Issue:16
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1347045 | Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot counterscreen GloSensor control cell line | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID1347405 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS LOPAC collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347050 | Natriuretic polypeptide receptor (hNpr2) antagonism - Pilot subtype selectivity assay | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347049 | Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1347059 | CD47-SIRPalpha protein protein interaction - Alpha assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1347057 | CD47-SIRPalpha protein protein interaction - LANCE assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6
| A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| AID219220 | Evaluated for Potassium ion content of Cerebrocortical slices in cat with addition of Sodium Bicarbonate (NaHCO3) and at a compound concentration of 1 X 10E-5 M | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID15233 | Distribution coefficient (D %) between octanol and buffer of pH 7.4 | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID48340 | In vitro inhibition of HCO3- stimulated swelling in cat cerebrocortical tissue slice; No inhibition occurred | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID227342 | Compound at a concentration of 1 X 10E-5 M along with addition of Sodium Bicarbonate (NaHCO3) was tested for percent bicarbonate stimulated swelling of Cerebrocortical slices in cat (in vitro) | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID219217 | Compound at a concentration of 1 X 10E-5 M along with addition of Sodium Bicarbonate (NaHCO3) was tested for percent bicarbonate stimulated swelling of Cerebrocortical slices in cat (in vitro) | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID49779 | In vitro inhibition of tissue swelling of Cerebrocortical slices from cat with addition of Sodium Bicarbonate (NaHCO3) and at a compound concentration of 1 X 10E-5 M | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID58924 | Relative salidiuretic efficacy was scored in dog; weak | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID26315 | Dissociation constant (pKa) (determined in 30% EtOH) | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID219218 | Compound at a concentration of 1 X 10E-5 M along with addition of Triethylammonium Bicarbonate (TEAB) was tested for percent bicarbonate stimulated swelling of Cerebrocortical slices in cat (in vitro) | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID49889 | Evaluated for chloride ion content of Cerebrocortical slices in cat with addition of Sodium Bicarbonate (NaHCO3) and at a compound concentration of 1 X 10E-5 M | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID187641 | Relative salidiuretic efficacy was scored in Rat; moderate | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID219222 | Evaluated for Potassium ion content of Cerebrocortical slices in cat with addition of Triethylammonium Bicarbonate (TEAB) and at a compound concentration of 1 X 10E-5 M. | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID52074 | Relative salidiuretic efficacy was scored in chimpanzee; moderate | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID49890 | Evaluated for chloride ion content of Cerebrocortical slices in cat with addition of Triethylammonium Bicarbonate (TEAB) and at a compound concentration of 1 X 10E-5 M. | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID49893 | In vitro inhibition of tissue swelling of Cerebrocortical slices from cat with addition of Triethylammonium Bicarbonate (TEAB) and at a compound concentration of 1 X 10E-5 M. | 1982 | Journal of medicinal chemistry, May, Volume: 25, Issue:5
| Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |