Page last updated: 2024-10-22

am 251 and Pruritus

am 251 has been researched along with Pruritus in 3 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.

Research Excerpts

ExcerptRelevanceReference
"Emesis was induced in ferrets with morphine-6-glucuronide (0."7.74A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient. ( Miller, MJ; Reuter, BK; Sharkey, KA; Wallace, JL, 2008)
"Emesis was induced in ferrets with morphine-6-glucuronide (0."3.74A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient. ( Miller, MJ; Reuter, BK; Sharkey, KA; Wallace, JL, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilir, KA1
Anli, G1
Ozkan, E1
Gunduz, O2
Ulugol, A2
Saglam, G1
Miller, MJ1
Reuter, BK1
Wallace, JL1
Sharkey, KA1

Other Studies

3 other studies available for am 251 and Pruritus

ArticleYear
Involvement of spinal cannabinoid receptors in the antipruritic effects of WIN 55,212-2, a cannabinoid receptor agonist.
    Clinical and experimental dermatology, 2018, Volume: 43, Issue:5

    Topics: Animals; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Respons

2018
Blockade of cannabinoid CB1 and CB2 receptors does not prevent the antipruritic effect of systemic paracetamol.
    Acta neurologica Belgica, 2014, Volume: 114, Issue:4

    Topics: Acetaminophen; Animals; Antipruritics; Camphanes; Disease Models, Animal; Dose-Response Relationship

2014
A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient.
    Journal of translational medicine, 2008, Jan-18, Volume: 6

    Topics: Animals; Antiemetics; Antipruritics; Cell Line; Croton; Ferrets; Male; Mice; Mice, Inbred C57BL; Mor

2008