am 251 has been researched along with Pruritus in 3 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Emesis was induced in ferrets with morphine-6-glucuronide (0." | 7.74 | A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient. ( Miller, MJ; Reuter, BK; Sharkey, KA; Wallace, JL, 2008) |
| "Emesis was induced in ferrets with morphine-6-glucuronide (0." | 3.74 | A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient. ( Miller, MJ; Reuter, BK; Sharkey, KA; Wallace, JL, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilir, KA | 1 |
| Anli, G | 1 |
| Ozkan, E | 1 |
| Gunduz, O | 2 |
| Ulugol, A | 2 |
| Saglam, G | 1 |
| Miller, MJ | 1 |
| Reuter, BK | 1 |
| Wallace, JL | 1 |
| Sharkey, KA | 1 |
3 other studies available for am 251 and Pruritus
| Article | Year |
|---|---|
Involvement of spinal cannabinoid receptors in the antipruritic effects of WIN 55,212-2, a cannabinoid receptor agonist.
Topics: Animals; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Respons | 2018 |
Blockade of cannabinoid CB1 and CB2 receptors does not prevent the antipruritic effect of systemic paracetamol.
Topics: Acetaminophen; Animals; Antipruritics; Camphanes; Disease Models, Animal; Dose-Response Relationship | 2014 |
A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient.
Topics: Animals; Antiemetics; Antipruritics; Cell Line; Croton; Ferrets; Male; Mice; Mice, Inbred C57BL; Mor | 2008 |