ondansetron has been researched along with Pruritus in 67 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study's purpose was to determine if ondansetron can prevent pruritus after administration of intrathecal morphine in children, as has been demonstrated in adults." | 9.51 | Intravenous ondansetron reduced nausea but not pruritus following intrathecal morphine in children: Interim results of a randomized, double-blinded, placebo-control trial. ( Hong, RA; Leis, A; Li, Y; Malviya, S; Park, JM; Putnam, EM, 2022) |
| "The objective of this randomised, double blinded clinical trial was to evaluate the efficacy of prophylactic administration of 4 mg ondansetron as monotherapy versus combination therapy of 4 mg ondansetron plus 8 mg dexamethasone for the prevention of intrathecal morphine-associated pruritus in caesarean section within 24 h." | 9.41 | Ondansetron versus ondansetron with dexamethasone to prevent intrathecal-morphine pruritus for caesarean patients: randomised double-blind trial. ( Ankouni, T; El Hassan, J; El Khatib, R; Itani, SE; Kanawati, S; Naja, Z; Rajab, O, 2021) |
| "Pregabalin is an effective alternative for treatment of uraemic pruritus." | 9.20 | Comparison of pregabalin with ondansetron in treatment of uraemic pruritus in dialysis patients: a prospective, randomized, double-blind study. ( Jiao, S; Meng, J; Ren, W; Xiao, Y; Yue, J; Zhao, T, 2015) |
| "Prophylactic administration of ondansetron to parturients receiving intrathecal morphine for post-operative analgesia provides a significant reduction of intrathecal morphine-induced pruritus and nausea and vomiting." | 9.20 | Prophylactic administration of ondansetron in prevention of intrathecal morphine-induced pruritus and post-operative nausea and vomiting in patients undergoing caesarean section. ( Dongol, Y; Gurung, BS; Koju, RB, 2015) |
| "Healthy paturients undergoing cesarean delivery with intrathecal morphine 250μg and fentanyl 25μg were randomized to receive: prophylaxis (ondansetron 8mg at cord clamping, normal saline 4mL for treatment of pruritus in the post-anaesthesia care unit); treatment (normal saline 4mL at cord clamping, ondansetron 8mg as required in the post-anesthesia care unit) or control (normal saline 4mL in both)." | 9.19 | Prevention versus treatment of intrathecal morphine-induced pruritus with ondansetron. ( Hess, P; Kung, AT; Li, Y; Pratt, S; Vasudevan, A; Yang, X, 2014) |
| "Ondansetron is as effective as diphenhydramine in relieving pruritus caused by SA morphine in patients undergoing a cesarean delivery." | 9.14 | Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. ( Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW, 2010) |
| "Ondansetron is effective for the treatment of intrathecal morphine-induced pruritus." | 9.14 | A randomized controlled trial of pentazocine versus ondansetron for the treatment of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. ( Charuluxananan, S; Patumanond, J; Punjasawadwong, Y; Sriprajittichai, P; Tamdee, D; Tawichasri, C, 2009) |
| " reduces the severity of pruritus and the use of rescue anti-pruritic medication, and improves satisfaction but does not reduce the overall incidence of pruritus in women who have received subarachnoid morphine 150 microg compared to ondansetron 8 mg i." | 9.14 | Reduction of severity of pruritus after elective caesarean section under spinal anaesthesia with subarachnoid morphine: a randomised comparison of prophylactic granisetron and ondansetron. ( Carey, M; Choroszczak, P; Immani, S; Ojo, R; Tan, T, 2010) |
| "Seventeen patients with severe pruritus complicating established chronic liver disease were randomized to receive, double-blind, ondansetron (8 mg) or a placebo orally; each was administered thrice daily for a 4-week period." | 9.12 | Ondansetron and pruritus in chronic liver disease: a controlled study. ( Jones, EA; Molenaar, HA; Oosting, J, 2007) |
| "In this randomized, double-blind study, we aimed to compare the effectiveness of lornoxicam and ondansetron for the prevention of intrathecal fentanyl-induced pruritus in patients undergoing cesarean section." | 9.12 | Lornoxicam and ondansetron for the prevention of intrathecal fentanyl-induced pruritus. ( Begec, Z; Erdil, FA; Ersoy, MO; Gedik, E; Gulhas, N; Sagir, O; Togal, T, 2007) |
| " The incidence of pruritus and nausea was significantly lower in the epidural ondansetron group than in the intravenous ondansetron group at 24 and 48 h postoperatively." | 9.12 | Epidural ondansetron is more effective to prevent postoperative pruritus and nausea than intravenous ondansetron in elective cesarean delivery. ( Han, DW; Hong, SW; Kim, KJ; Kwon, JY; Lee, JW, 2007) |
| "Neither ondansetron nor tropisetron prevent itching caused by intrathecal morphine with fentanyl." | 9.12 | Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery. ( Halonen, PM; Kainu, JP; Korttila, KT; Sarvela, PJ; Soikkeli, AI, 2006) |
| "We compared the efficacy of granisetron and ondansetron for the prevention of subarachnoid morphine-induced pruritus after cesarean delivery." | 9.12 | Does ondansetron or granisetron prevent subarachnoid morphine-induced pruritus after cesarean delivery? ( Aouad, MT; Azar, MS; Baraka, AS; Hakki, MA; Kaddoum, RN; Nasr, VG; Siddik-Sayyid, SM; Taha, SK; Yazbek, VG, 2007) |
| "Fentanyl is commonly used for spinal analgesia during labour but it is associated with a high incidence of pruritus." | 9.11 | Intrathecal fentanyl-induced pruritus during labour: the effect of prophylactic ondansetron. ( Evans, SF; Paech, MJ; Wells, J, 2004) |
| "To determine whether ondansetron is effective in treating the pruritus of cholestasis." | 9.11 | A controlled trial of ondansetron in the pruritus of cholestasis. ( Ashdown, AC; Haigh, CG; O'Donohue, JW; Pereira, SP; Wilkinson, JR; Williams, R, 2005) |
| "In this study we compared the efficacy of orally disintegrating tablets (ODT) and IV ondansetron for preventing spinal morphine-induced pruritus and postoperative nausea and vomiting (PONV) in healthy young male patients." | 9.11 | Ondansetron, orally disintegrating tablets versus intravenous injection for prevention of intrathecal morphine-induced nausea, vomiting, and pruritus in young males. ( Arslan, G; Candan, S; Pirat, A; Torgay, A; Tuncay, ŞF, 2005) |
| "Pruritus is the most common side effect of intrathecal morphine for postoperative pain relief." | 9.11 | Prophylactic intravenous ondansetron and dolasetron in intrathecal morphine-induced pruritus: a randomized, double-blinded, placebo-controlled study. ( Dimitriou, VK; Dragoumanis, CK; Iatrou, CA; Simopoulos, CE; Vogiatzaki, TD; Vretzakis, GI, 2005) |
| "To assess the safety and efficacy of ondansetron for prevention of pruritus, nausea and vomiting after cesarean delivery with intrathecal sufentanil-morphine." | 9.10 | Prophylactic ondansetron is effective in the treatment of nausea and vomiting but not on pruritus after cesarean delivery with intrathecal sufentanil-morphine. ( Chalhoub, V; Haddad, F; Hayek, G; Madi-Jebara, S; Yazigi, A, 2002) |
| "We conclude that iv ondansetron 4 mg is effective in the prevention of nausea, vomiting, and pruritus following epidural morphine for postoperative pain control." | 9.10 | Prophylactic iv ondansetron reduces nausea, vomiting and pruritus following epidural morphine for postoperative pain control. ( Cheng, KI; Chu, KS; Ho, ST; Liu, KS; Tzeng, JI; Wang, JJ, 2003) |
| " However, the intrathecal fentanyl-induced pruritus is as high as 75%." | 9.10 | Ondansetron does not prevent pruritus induced by low-dose intrathecal fentanyl. ( Jokela, RM; Korhonen, AM; Korttila, K; Ravaska, P; Valanne, JV, 2003) |
| "In this prospective, randomized, double-blinded study, we compared the prophylactic efficacy of nalbuphine and ondansetron for the prevention of intrathecal morphine-induced pruritus after cesarean delivery." | 9.10 | Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery. ( Charuluxananan, S; Kyokong, O; Narasethakamol, A; Promlok, P; Somboonviboon, W, 2003) |
| "Elevated plasma histamine levels are considered to play a part in the pathophysiology of hemodialysis-related pruritus." | 9.10 | Plasma serotonin and histamine levels in hemodialysis-related pruritus are not significantly influenced by 5-HT3 receptor blocker and antihistaminic therapy. ( Domröse, U; Dunker, N; Gollnick, H; Neumann, KH; Weisshaar, E, 2003) |
| "We investigated the effectiveness of prophylactic IV ondansetron in preventing intrathecal fentanyl-induced pruritus." | 9.10 | Prophylactic ondansetron reduces the incidence of intrathecal fentanyl-induced pruritus. ( Gürkan, Y; Toker, K, 2002) |
| "In a prospective, randomized, double-blind, placebo-controlled study, 100 patients with pruritus (> 4 on a visual analog scale, on which 0 represents no pruritus and 10 represents worst pruritus imaginable) after spinal or epidural administration of morphine, received either 8 mg ondansetron intravenously (ondansetron group) in 100 ml NaCl 0." | 9.09 | Ondansetron is effective to treat spinal or epidural morphine-induced pruritus. ( Borgeat, A; Stirnemann, HR, 1999) |
| "Ondansetron prophylaxis significantly decreases the incidence of pruritus, a common side effect of intrathecal morphine used to treat postcesarean delivery pain." | 9.09 | Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. ( Chan, WH; Chen, LK; Chen, YP; Lin, CJ; Lin, CS; Sun, WZ; Tsai, SK; Wang, MJ; Yeh, HM, 2000) |
| "Recently, the serotonin antagonist ondansetron has been reported to have a positive effect on cholestasis-associated pruritus." | 9.08 | Treatment of pruritus in chronic liver disease with the 5-hydroxytryptamine receptor type 3 antagonist ondansetron: a randomized, placebo-controlled, double-blind cross-over trial. ( Ferenci, P; Kaider, A; Müller, C; Penner, E; Pidlich, J; Pongratz, S; Raderer, M; Scheithauer, W; Schemper, M, 1998) |
| "The objective of the present study was to determine whether ondansetron, a specific serotonin type 3 receptor antagonist (5-HT3), relieves cholestatic pruritus in patients resistant to conventional antipruritic therapy (antihistamines and cholestyramine)." | 9.08 | Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron. ( Hartmann, H; Ramadori, G; Schwörer, H, 1995) |
| "Pruritus is one of the most common adverse effects associated with neuraxial morphine." | 8.95 | Ondansetron for neuraxial morphine-induced pruritus: A meta-analysis of randomized controlled trials. ( Sun, L; Wang, W; Zhou, L, 2017) |
| "Pruritus is a common side effect of intrathecal fentanyl or sufentanil that decreases patient satisfaction and may delay hospital discharge." | 8.93 | Prophylactic Ondansetron for the Prevention of Intrathecal Fentanyl- or Sufentanil-Mediated Pruritus: A Meta-Analysis of Randomized Trials. ( Guglielminotti, J; Li, G; Moitra, V; Prin, M, 2016) |
| "This review of the literature systematically explores the role of ondansetron in the management of cholestatic or uremic pruritus." | 8.88 | The role of ondansetron in the management of cholestatic or uremic pruritus--a systematic review. ( Clark, K; Currow, DC; Lam, L; Shelby-James, T; To, TH, 2012) |
| "To examine non-clinical and clinical data relevant to the hypothesis that ondansetron, a 5-HT(3) receptor subtype antagonist, ameliorates pruritus and fatigue in liver disease." | 8.84 | Pruritus and fatigue associated with liver disease: is there a role for ondansetron? ( Jones, EA, 2008) |
| "Ondansetron decreased pruritus intensity in prurigo simplex (four patients), asteatotic eczema (two patients), parapsoriasis en plaques, and pruritus of unknown origin (one patient each)." | 7.72 | [Therapy of pruritus associated with skin diseases with the serotonin receptor antagonist ondansetron]. ( Degitz, K; Schuh, T; Zenker, S, 2003) |
| "Pruritus is a common, unpleasant symptom of uremic patients." | 6.69 | Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients. ( Balaskas, EV; Bamihas, GI; Karamouzis, M; Tourkantonis, A; Voyiatzis, G, 1998) |
| "Pruritus is a distressing symptom affecting up to 90% of dialysis patients." | 6.69 | Ondansetron therapy for uremic pruritus in hemodialysis patients. ( Ashmore, SD; Chrystyn, H; Daly, MJ; Jones, CH; Newstead, CG, 2000) |
| "This study's purpose was to determine if ondansetron can prevent pruritus after administration of intrathecal morphine in children, as has been demonstrated in adults." | 5.51 | Intravenous ondansetron reduced nausea but not pruritus following intrathecal morphine in children: Interim results of a randomized, double-blinded, placebo-control trial. ( Hong, RA; Leis, A; Li, Y; Malviya, S; Park, JM; Putnam, EM, 2022) |
| "The objective of this randomised, double blinded clinical trial was to evaluate the efficacy of prophylactic administration of 4 mg ondansetron as monotherapy versus combination therapy of 4 mg ondansetron plus 8 mg dexamethasone for the prevention of intrathecal morphine-associated pruritus in caesarean section within 24 h." | 5.41 | Ondansetron versus ondansetron with dexamethasone to prevent intrathecal-morphine pruritus for caesarean patients: randomised double-blind trial. ( Ankouni, T; El Hassan, J; El Khatib, R; Itani, SE; Kanawati, S; Naja, Z; Rajab, O, 2021) |
| "Severe uraemic pruritus is rare, but distressing in children and can improve with ondansetron." | 5.32 | Ondansetron for paediatric uraemic pruritus: a case report. ( Deshpande, PV, 2004) |
| "Ondansetron appears to be a beneficial and safe method of relieving pruritus associated with intrathecal morphine." | 5.29 | The use of ondansetron to treat pruritus associated with intrathecal morphine in two paediatric patients. ( Arai, L; Dorsey, A; Schwartz, R; Stayer, S, 1996) |
| "Prophylactic administration of ondansetron to parturients receiving intrathecal morphine for post-operative analgesia provides a significant reduction of intrathecal morphine-induced pruritus and nausea and vomiting." | 5.20 | Prophylactic administration of ondansetron in prevention of intrathecal morphine-induced pruritus and post-operative nausea and vomiting in patients undergoing caesarean section. ( Dongol, Y; Gurung, BS; Koju, RB, 2015) |
| "Pregabalin is an effective alternative for treatment of uraemic pruritus." | 5.20 | Comparison of pregabalin with ondansetron in treatment of uraemic pruritus in dialysis patients: a prospective, randomized, double-blind study. ( Jiao, S; Meng, J; Ren, W; Xiao, Y; Yue, J; Zhao, T, 2015) |
| "Healthy paturients undergoing cesarean delivery with intrathecal morphine 250μg and fentanyl 25μg were randomized to receive: prophylaxis (ondansetron 8mg at cord clamping, normal saline 4mL for treatment of pruritus in the post-anaesthesia care unit); treatment (normal saline 4mL at cord clamping, ondansetron 8mg as required in the post-anesthesia care unit) or control (normal saline 4mL in both)." | 5.19 | Prevention versus treatment of intrathecal morphine-induced pruritus with ondansetron. ( Hess, P; Kung, AT; Li, Y; Pratt, S; Vasudevan, A; Yang, X, 2014) |
| "Ondansetron is as effective as diphenhydramine in relieving pruritus caused by SA morphine in patients undergoing a cesarean delivery." | 5.14 | Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. ( Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW, 2010) |
| " reduces the severity of pruritus and the use of rescue anti-pruritic medication, and improves satisfaction but does not reduce the overall incidence of pruritus in women who have received subarachnoid morphine 150 microg compared to ondansetron 8 mg i." | 5.14 | Reduction of severity of pruritus after elective caesarean section under spinal anaesthesia with subarachnoid morphine: a randomised comparison of prophylactic granisetron and ondansetron. ( Carey, M; Choroszczak, P; Immani, S; Ojo, R; Tan, T, 2010) |
| "Ondansetron is effective for the treatment of intrathecal morphine-induced pruritus." | 5.14 | A randomized controlled trial of pentazocine versus ondansetron for the treatment of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. ( Charuluxananan, S; Patumanond, J; Punjasawadwong, Y; Sriprajittichai, P; Tamdee, D; Tawichasri, C, 2009) |
| " The incidence of pruritus and nausea was significantly lower in the epidural ondansetron group than in the intravenous ondansetron group at 24 and 48 h postoperatively." | 5.12 | Epidural ondansetron is more effective to prevent postoperative pruritus and nausea than intravenous ondansetron in elective cesarean delivery. ( Han, DW; Hong, SW; Kim, KJ; Kwon, JY; Lee, JW, 2007) |
| "We compared the efficacy of granisetron and ondansetron for the prevention of subarachnoid morphine-induced pruritus after cesarean delivery." | 5.12 | Does ondansetron or granisetron prevent subarachnoid morphine-induced pruritus after cesarean delivery? ( Aouad, MT; Azar, MS; Baraka, AS; Hakki, MA; Kaddoum, RN; Nasr, VG; Siddik-Sayyid, SM; Taha, SK; Yazbek, VG, 2007) |
| "Neither ondansetron nor tropisetron prevent itching caused by intrathecal morphine with fentanyl." | 5.12 | Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery. ( Halonen, PM; Kainu, JP; Korttila, KT; Sarvela, PJ; Soikkeli, AI, 2006) |
| "Seventeen patients with severe pruritus complicating established chronic liver disease were randomized to receive, double-blind, ondansetron (8 mg) or a placebo orally; each was administered thrice daily for a 4-week period." | 5.12 | Ondansetron and pruritus in chronic liver disease: a controlled study. ( Jones, EA; Molenaar, HA; Oosting, J, 2007) |
| "In this randomized, double-blind study, we aimed to compare the effectiveness of lornoxicam and ondansetron for the prevention of intrathecal fentanyl-induced pruritus in patients undergoing cesarean section." | 5.12 | Lornoxicam and ondansetron for the prevention of intrathecal fentanyl-induced pruritus. ( Begec, Z; Erdil, FA; Ersoy, MO; Gedik, E; Gulhas, N; Sagir, O; Togal, T, 2007) |
| "To determine whether ondansetron is effective in treating the pruritus of cholestasis." | 5.11 | A controlled trial of ondansetron in the pruritus of cholestasis. ( Ashdown, AC; Haigh, CG; O'Donohue, JW; Pereira, SP; Wilkinson, JR; Williams, R, 2005) |
| "In this study we compared the efficacy of orally disintegrating tablets (ODT) and IV ondansetron for preventing spinal morphine-induced pruritus and postoperative nausea and vomiting (PONV) in healthy young male patients." | 5.11 | Ondansetron, orally disintegrating tablets versus intravenous injection for prevention of intrathecal morphine-induced nausea, vomiting, and pruritus in young males. ( Arslan, G; Candan, S; Pirat, A; Torgay, A; Tuncay, ŞF, 2005) |
| "Pruritus is the most common side effect of intrathecal morphine for postoperative pain relief." | 5.11 | Prophylactic intravenous ondansetron and dolasetron in intrathecal morphine-induced pruritus: a randomized, double-blinded, placebo-controlled study. ( Dimitriou, VK; Dragoumanis, CK; Iatrou, CA; Simopoulos, CE; Vogiatzaki, TD; Vretzakis, GI, 2005) |
| "Fentanyl is commonly used for spinal analgesia during labour but it is associated with a high incidence of pruritus." | 5.11 | Intrathecal fentanyl-induced pruritus during labour: the effect of prophylactic ondansetron. ( Evans, SF; Paech, MJ; Wells, J, 2004) |
| "Elevated plasma histamine levels are considered to play a part in the pathophysiology of hemodialysis-related pruritus." | 5.10 | Plasma serotonin and histamine levels in hemodialysis-related pruritus are not significantly influenced by 5-HT3 receptor blocker and antihistaminic therapy. ( Domröse, U; Dunker, N; Gollnick, H; Neumann, KH; Weisshaar, E, 2003) |
| "We investigated the effectiveness of prophylactic IV ondansetron in preventing intrathecal fentanyl-induced pruritus." | 5.10 | Prophylactic ondansetron reduces the incidence of intrathecal fentanyl-induced pruritus. ( Gürkan, Y; Toker, K, 2002) |
| "We conclude that iv ondansetron 4 mg is effective in the prevention of nausea, vomiting, and pruritus following epidural morphine for postoperative pain control." | 5.10 | Prophylactic iv ondansetron reduces nausea, vomiting and pruritus following epidural morphine for postoperative pain control. ( Cheng, KI; Chu, KS; Ho, ST; Liu, KS; Tzeng, JI; Wang, JJ, 2003) |
| " However, the intrathecal fentanyl-induced pruritus is as high as 75%." | 5.10 | Ondansetron does not prevent pruritus induced by low-dose intrathecal fentanyl. ( Jokela, RM; Korhonen, AM; Korttila, K; Ravaska, P; Valanne, JV, 2003) |
| "In a prospective, double-blinded, randomized trial, we evaluated the efficacy of IV (a) dexamethasone 8 mg, (b) ondansetron 8 mg, and (c) dexamethasone 8 mg plus ondansetron 4 mg for the prevention of postoperative nausea, vomiting (PONV), and pruritus in 130 (ASA physical status I to III) patients undergoing elective major orthopedic surgery after spinal anesthesia with hyperbaric 0." | 5.10 | A comparison of dexamethasone, ondansetron, and dexamethasone plus ondansetron as prophylactic antiemetic and antipruritic therapy in patients receiving intrathecal morphine for major orthopedic surgery. ( Chellapuri, RS; Harmon, DC; Murphy, D; Owens, J; Shorten, GD; Szarvas, S, 2003) |
| "In this prospective, randomized, double-blinded study, we compared the prophylactic efficacy of nalbuphine and ondansetron for the prevention of intrathecal morphine-induced pruritus after cesarean delivery." | 5.10 | Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery. ( Charuluxananan, S; Kyokong, O; Narasethakamol, A; Promlok, P; Somboonviboon, W, 2003) |
| "To assess the safety and efficacy of ondansetron for prevention of pruritus, nausea and vomiting after cesarean delivery with intrathecal sufentanil-morphine." | 5.10 | Prophylactic ondansetron is effective in the treatment of nausea and vomiting but not on pruritus after cesarean delivery with intrathecal sufentanil-morphine. ( Chalhoub, V; Haddad, F; Hayek, G; Madi-Jebara, S; Yazigi, A, 2002) |
| "In a prospective, randomized, double-blind, placebo-controlled study, 100 patients with pruritus (> 4 on a visual analog scale, on which 0 represents no pruritus and 10 represents worst pruritus imaginable) after spinal or epidural administration of morphine, received either 8 mg ondansetron intravenously (ondansetron group) in 100 ml NaCl 0." | 5.09 | Ondansetron is effective to treat spinal or epidural morphine-induced pruritus. ( Borgeat, A; Stirnemann, HR, 1999) |
| "We have evaluated the efficacy of ondansetron in the prevention of opioid-induced pruritus in a prospective, randomized, double-blind, placebo-controlled study." | 5.09 | Management of opioid-induced pruritus: a role for 5-HT3 antagonists? ( Hobbs, GJ; Hussain, SK; Kyriakides, K, 1999) |
| "Ondansetron prophylaxis significantly decreases the incidence of pruritus, a common side effect of intrathecal morphine used to treat postcesarean delivery pain." | 5.09 | Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. ( Chan, WH; Chen, LK; Chen, YP; Lin, CJ; Lin, CS; Sun, WZ; Tsai, SK; Wang, MJ; Yeh, HM, 2000) |
| "The objective of the present study was to determine whether ondansetron, a specific serotonin type 3 receptor antagonist (5-HT3), relieves cholestatic pruritus in patients resistant to conventional antipruritic therapy (antihistamines and cholestyramine)." | 5.08 | Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron. ( Hartmann, H; Ramadori, G; Schwörer, H, 1995) |
| "Recently, the serotonin antagonist ondansetron has been reported to have a positive effect on cholestasis-associated pruritus." | 5.08 | Treatment of pruritus in chronic liver disease with the 5-hydroxytryptamine receptor type 3 antagonist ondansetron: a randomized, placebo-controlled, double-blind cross-over trial. ( Ferenci, P; Kaider, A; Müller, C; Penner, E; Pidlich, J; Pongratz, S; Raderer, M; Scheithauer, W; Schemper, M, 1998) |
| "Pruritus is one of the most common adverse effects associated with neuraxial morphine." | 4.95 | Ondansetron for neuraxial morphine-induced pruritus: A meta-analysis of randomized controlled trials. ( Sun, L; Wang, W; Zhou, L, 2017) |
| "Pruritus is a common side effect of intrathecal fentanyl or sufentanil that decreases patient satisfaction and may delay hospital discharge." | 4.93 | Prophylactic Ondansetron for the Prevention of Intrathecal Fentanyl- or Sufentanil-Mediated Pruritus: A Meta-Analysis of Randomized Trials. ( Guglielminotti, J; Li, G; Moitra, V; Prin, M, 2016) |
| "This review of the literature systematically explores the role of ondansetron in the management of cholestatic or uremic pruritus." | 4.88 | The role of ondansetron in the management of cholestatic or uremic pruritus--a systematic review. ( Clark, K; Currow, DC; Lam, L; Shelby-James, T; To, TH, 2012) |
| "To examine non-clinical and clinical data relevant to the hypothesis that ondansetron, a 5-HT(3) receptor subtype antagonist, ameliorates pruritus and fatigue in liver disease." | 4.84 | Pruritus and fatigue associated with liver disease: is there a role for ondansetron? ( Jones, EA, 2008) |
| "The use of ondansetron, a selective serotonin 5-HT3 receptor antagonist, is well established in patients with nausea and vomiting associated with cancer chemotherapy, radiotherapy or anaesthesia and surgery." | 4.79 | Ondansetron. A review of its pharmacology and preliminary clinical findings in novel applications. ( Markham, A; Wilde, MI, 1996) |
| "Ondansetron decreased pruritus intensity in prurigo simplex (four patients), asteatotic eczema (two patients), parapsoriasis en plaques, and pruritus of unknown origin (one patient each)." | 3.72 | [Therapy of pruritus associated with skin diseases with the serotonin receptor antagonist ondansetron]. ( Degitz, K; Schuh, T; Zenker, S, 2003) |
| " In three patients with generalized pruritus, intravenous administration of the serotonin type 3 (5-HT3) receptor antagonist ondansetron induced a marked relief of itching." | 3.68 | Treatment of pruritus: a new indication for serotonin type 3 receptor antagonists. ( Ramadori, G; Schwörer, H, 1993) |
| "Pruritus is the most distressing symptom in haemodialysis (HD) patients." | 2.71 | Antipruritic effects of two different 5-HT3 receptor antagonists and an antihistamine in haemodialysis patients. ( Dunker, N; Gollnick, H; Röhl, FW; Weisshaar, E, 2004) |
| "Pruritus is a common, unpleasant symptom of uremic patients." | 2.69 | Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients. ( Balaskas, EV; Bamihas, GI; Karamouzis, M; Tourkantonis, A; Voyiatzis, G, 1998) |
| "Pruritus is a distressing symptom affecting up to 90% of dialysis patients." | 2.69 | Ondansetron therapy for uremic pruritus in hemodialysis patients. ( Ashmore, SD; Chrystyn, H; Daly, MJ; Jones, CH; Newstead, CG, 2000) |
| "Post-burn pruritus is the pruritus that occurs after burn during the rehabilitation and healing process of burn wounds." | 2.66 | Post-Burn Pruritus. ( Chung, BY; Jung, MJ; Kang, SY; Kim, HB; Kim, HO; Kwak, IS; Park, CW, 2020) |
| "Pruritus is often the most troublesome symptom in patients with chronic liver disease, particularly when cholestasis is a prominent feature." | 2.42 | Review article: pruritus in cholestatic and other liver diseases. ( Burroughs, AK; Mancuso, A; Mela, M, 2003) |
| "Pruritus is a common adverse effect of opioids, particularly after spinal and epidural administration." | 1.38 | [Opioid-induced pruritus]. ( Frost, J; Spigset, O, 2012) |
| "Severe uraemic pruritus is rare, but distressing in children and can improve with ondansetron." | 1.32 | Ondansetron for paediatric uraemic pruritus: a case report. ( Deshpande, PV, 2004) |
| "The treatment with ondansetron may also have effects on the pruritus of patients with cholestasis." | 1.32 | [Pathogenesis and treatment of pruritus in patients with cholestasis]. ( Blumenstein, I; Schirrmacher, S; Stein, J, 2003) |
| "Ondansetron appears to be a beneficial and safe method of relieving pruritus associated with intrathecal morphine." | 1.29 | The use of ondansetron to treat pruritus associated with intrathecal morphine in two paediatric patients. ( Arai, L; Dorsey, A; Schwartz, R; Stayer, S, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (26.87) | 18.2507 |
| 2000's | 34 (50.75) | 29.6817 |
| 2010's | 12 (17.91) | 24.3611 |
| 2020's | 3 (4.48) | 2.80 |
| Authors | Studies |
|---|---|
| Putnam, EM | 1 |
| Hong, RA | 1 |
| Park, JM | 1 |
| Li, Y | 2 |
| Leis, A | 1 |
| Malviya, S | 1 |
| Chung, BY | 1 |
| Kim, HB | 1 |
| Jung, MJ | 1 |
| Kang, SY | 1 |
| Kwak, IS | 1 |
| Park, CW | 1 |
| Kim, HO | 1 |
| Ankouni, T | 1 |
| Kanawati, S | 1 |
| El Khatib, R | 1 |
| El Hassan, J | 1 |
| Itani, SE | 1 |
| Rajab, O | 1 |
| Naja, Z | 1 |
| Wang, W | 1 |
| Zhou, L | 1 |
| Sun, L | 1 |
| Kung, AT | 1 |
| Yang, X | 1 |
| Vasudevan, A | 1 |
| Pratt, S | 1 |
| Hess, P | 1 |
| Yue, J | 1 |
| Jiao, S | 1 |
| Xiao, Y | 1 |
| Ren, W | 1 |
| Zhao, T | 1 |
| Meng, J | 1 |
| Ostadhadi, S | 1 |
| Kordjazy, N | 1 |
| Haj-Mirzaian, A | 1 |
| Mansouri, P | 1 |
| Dehpour, AR | 1 |
| Koju, RB | 1 |
| Gurung, BS | 1 |
| Dongol, Y | 1 |
| Prin, M | 1 |
| Guglielminotti, J | 1 |
| Moitra, V | 1 |
| Li, G | 1 |
| Adam, F | 1 |
| Tamdee, D | 1 |
| Charuluxananan, S | 3 |
| Punjasawadwong, Y | 1 |
| Tawichasri, C | 1 |
| Patumanond, J | 1 |
| Sriprajittichai, P | 1 |
| Tan, T | 1 |
| Ojo, R | 1 |
| Immani, S | 1 |
| Choroszczak, P | 1 |
| Carey, M | 1 |
| Siddik-Sayyid, SM | 3 |
| Yazbeck-Karam, VG | 1 |
| Zahreddine, BW | 1 |
| Adham, AM | 1 |
| Dagher, CM | 1 |
| Saasouh, WA | 1 |
| Aouad, MT | 2 |
| Aouad, M | 1 |
| To, TH | 1 |
| Clark, K | 1 |
| Lam, L | 1 |
| Shelby-James, T | 1 |
| Currow, DC | 1 |
| Frost, J | 1 |
| Spigset, O | 1 |
| Puttaswamy, RK | 1 |
| Valap, S | 1 |
| Pierson, R | 1 |
| Das, B | 1 |
| Hodges, M | 1 |
| Hodgson, R | 1 |
| Chaudhari, S | 1 |
| Botros, S | 1 |
| Moore, P | 1 |
| Gürkan, Y | 1 |
| Toker, K | 1 |
| Murphy, M | 1 |
| Reaich, D | 1 |
| Pai, P | 1 |
| Finn, P | 1 |
| Carmichael, AJ | 1 |
| Weisshaar, E | 3 |
| Dunker, N | 2 |
| Domröse, U | 1 |
| Neumann, KH | 1 |
| Gollnick, H | 3 |
| Mela, M | 1 |
| Mancuso, A | 1 |
| Burroughs, AK | 1 |
| Schirrmacher, S | 1 |
| Blumenstein, I | 1 |
| Stein, J | 1 |
| Kyokong, O | 2 |
| Somboonviboon, W | 2 |
| Narasethakamol, A | 2 |
| Promlok, P | 2 |
| Szarvas, S | 1 |
| Chellapuri, RS | 1 |
| Harmon, DC | 1 |
| Owens, J | 1 |
| Murphy, D | 1 |
| Shorten, GD | 1 |
| Korhonen, AM | 1 |
| Valanne, JV | 1 |
| Jokela, RM | 1 |
| Ravaska, P | 1 |
| Korttila, K | 1 |
| Tzeng, JI | 1 |
| Chu, KS | 1 |
| Ho, ST | 1 |
| Cheng, KI | 1 |
| Liu, KS | 1 |
| Wang, JJ | 1 |
| Deshpande, PV | 1 |
| Röhl, FW | 1 |
| Schumann, R | 1 |
| Hudcova, J | 1 |
| Wells, J | 1 |
| Paech, MJ | 1 |
| Evans, SF | 1 |
| O'Donohue, JW | 1 |
| Pereira, SP | 1 |
| Ashdown, AC | 1 |
| Haigh, CG | 1 |
| Wilkinson, JR | 1 |
| Williams, R | 1 |
| Feng, J | 1 |
| Sethi, A | 1 |
| Reyes-Múgica, M | 1 |
| Antaya, R | 1 |
| Pirat, A | 1 |
| Tuncay, ŞF | 1 |
| Torgay, A | 1 |
| Candan, S | 1 |
| Arslan, G | 1 |
| Iatrou, CA | 1 |
| Dragoumanis, CK | 1 |
| Vogiatzaki, TD | 1 |
| Vretzakis, GI | 1 |
| Simopoulos, CE | 1 |
| Dimitriou, VK | 1 |
| Zenker, S | 1 |
| Schuh, T | 1 |
| Degitz, K | 1 |
| Sarvela, PJ | 1 |
| Halonen, PM | 1 |
| Soikkeli, AI | 1 |
| Kainu, JP | 1 |
| Korttila, KT | 1 |
| Frigon, C | 1 |
| Desparmet, J | 1 |
| Ruiz Villaverde, R | 1 |
| Sánchez Cano, D | 1 |
| Villaverde Gutiérrez, C | 1 |
| Taha, SK | 1 |
| Azar, MS | 1 |
| Hakki, MA | 1 |
| Kaddoum, RN | 1 |
| Nasr, VG | 1 |
| Yazbek, VG | 1 |
| Baraka, AS | 1 |
| Gulhas, N | 1 |
| Erdil, FA | 1 |
| Sagir, O | 1 |
| Gedik, E | 1 |
| Togal, T | 1 |
| Begec, Z | 1 |
| Ersoy, MO | 1 |
| Han, DW | 1 |
| Hong, SW | 1 |
| Kwon, JY | 1 |
| Lee, JW | 1 |
| Kim, KJ | 1 |
| Jones, EA | 2 |
| Molenaar, HA | 1 |
| Oosting, J | 1 |
| Schwörer, H | 4 |
| Ramadori, G | 4 |
| Hartmann, H | 1 |
| Raderer, M | 2 |
| Müller, C | 2 |
| Scheithauer, W | 2 |
| Crighton, IM | 1 |
| Hobbs, GJ | 2 |
| Reid, MF | 1 |
| Quigley, C | 1 |
| Arai, L | 1 |
| Stayer, S | 1 |
| Schwartz, R | 1 |
| Dorsey, A | 1 |
| Trioche, P | 1 |
| Samuel, D | 1 |
| Odièvre, M | 1 |
| Labrune, P | 1 |
| Wilde, MI | 1 |
| Markham, A | 1 |
| Balaskas, EV | 1 |
| Bamihas, GI | 1 |
| Karamouzis, M | 1 |
| Voyiatzis, G | 1 |
| Tourkantonis, A | 1 |
| Downs, AM | 1 |
| Kennedy, CT | 1 |
| Lamelo Alfonsín, F | 1 |
| Vila Arias, M | 1 |
| San Martín Moreira, J | 1 |
| Silva César, M | 1 |
| Pongratz, S | 1 |
| Pidlich, J | 1 |
| Penner, E | 1 |
| Kaider, A | 1 |
| Schemper, M | 1 |
| Ferenci, P | 1 |
| Borgeat, A | 1 |
| Stirnemann, HR | 1 |
| Kyriakides, K | 1 |
| Hussain, SK | 1 |
| Dimitriou, V | 1 |
| Voyagis, GS | 1 |
| Ashmore, SD | 1 |
| Jones, CH | 1 |
| Newstead, CG | 1 |
| Daly, MJ | 1 |
| Chrystyn, H | 1 |
| Yeh, HM | 1 |
| Chen, LK | 1 |
| Lin, CJ | 1 |
| Chan, WH | 1 |
| Chen, YP | 1 |
| Lin, CS | 1 |
| Sun, WZ | 1 |
| Wang, MJ | 1 |
| Tsai, SK | 1 |
| Pernia, A | 1 |
| Calderón, E | 1 |
| Calderón Pla, E | 1 |
| Torres, LM | 1 |
| Braun, M | 1 |
| Lowitt, MH | 1 |
| Yazigi, A | 1 |
| Chalhoub, V | 1 |
| Madi-Jebara, S | 1 |
| Haddad, F | 1 |
| Hayek, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns[NCT06104540] | 24 participants (Anticipated) | Interventional | 2023-11-01 | Not yet recruiting | |||
| Role of Dexamethasone or Ondansetron in the Quality of Recovery After Intrathecal Morphine Administration in Patients Undergoing Lower Limb Surgery.[NCT03035942] | Phase 4 | 135 participants (Actual) | Interventional | 2017-01-02 | Completed | ||
| Effect of Intravenous Granisetron on Incidence and Severity of Intrathecal Morphine Induced Pruritus in Elective Cesarean Section[NCT03483870] | Phase 2 | 80 participants (Actual) | Interventional | 2018-06-01 | Completed | ||
| Quality of Recovery Following Administration of Transverse Abdominus Plane (TAP) Catheter as Compared to Intrathecal Morphine After Cesarean Delivery Under Spinal Anesthesia: a Prospective, Randomized Trial[NCT01593280] | 80 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | |||
| IRB-HSR# 14583: Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients[NCT01414777] | Phase 2/Phase 3 | 68 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| Comparison Between Ondansetron 8 mg and Lidocain 40 mg in Preventing Pain Due to Propofol Injection[NCT03134612] | Phase 2 | 104 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The occurrence of PONV will be registered during the PACU (NCT03035942)
Timeframe: 4h
| Intervention | Participants (Count of Participants) |
|---|---|
| O Group | 3 |
| D Group | 9 |
| S Group | 9 |
The occurrence of localized or generalized itching (patients who answered yes or no) (NCT03035942)
Timeframe: 24 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| O Group | 4 |
| D Group | 7 |
| S Group | 8 |
Pain were assessed every 15 minutes during postanesthesia care unit, where zero meant no pain and 10 the worst imaginable pain (higher values represent worse outcome). Twenty four hours after surgery, patients were asked to describe the highest pain score (NRS) during ward stay. (NCT03035942)
Timeframe: 24 hours
| Intervention | Score on a scale (NRS) (Median) |
|---|---|
| D Group | 0 |
| O Group | 5 |
| S Group | 2 |
Quality of Recovery Questionnaire (QoR-40). Minimum score 40 (very poor quality of recovery) and maximun score 200 (excellent quality of recovery). Higher scores mean better outcome (NCT03035942)
Timeframe: Twenty four hours after surgery by a blinded investigator
| Intervention | Score on a scale (Median) |
|---|---|
| O Group | 184 |
| D Group | 187 |
| S Group | 185 |
10 reviews available for ondansetron and Pruritus
| Article | Year |
|---|---|
Post-Burn Pruritus.
Topics: Animals; Antipsychotic Agents; Burns; Gabapentin; Histamine Antagonists; Humans; Inflammation; Kerat | 2020 |
Ondansetron for neuraxial morphine-induced pruritus: A meta-analysis of randomized controlled trials.
Topics: Analgesics, Opioid; Antipruritics; Humans; Incidence; Morphine; Ondansetron; Pruritus; Randomized Co | 2017 |
Prophylactic Ondansetron for the Prevention of Intrathecal Fentanyl- or Sufentanil-Mediated Pruritus: A Meta-Analysis of Randomized Trials.
Topics: Analgesics, Opioid; Antipruritics; Fentanyl; Humans; Injections, Spinal; Ondansetron; Pruritus; Rand | 2016 |
[Patient-controlled analgesia. Pain and Locoregional Anesthesia Committee and the Standards Committee of the French Society of Anesthesia and Intensive Care].
Topics: Analgesia, Patient-Controlled; Antiemetics; Droperidol; Drug Administration Routes; Drug Synergism; | 2009 |
The role of ondansetron in the management of cholestatic or uremic pruritus--a systematic review.
Topics: Adult; Aged; Aged, 80 and over; Cholestasis; Female; Humans; Male; Middle Aged; Ondansetron; Pruritu | 2012 |
Review article: pruritus in cholestatic and other liver diseases.
Topics: Anion Exchange Resins; Antipruritics; Cholagogues and Choleretics; Humans; Liver Diseases; Narcotic | 2003 |
Pruritus and fatigue associated with liver disease: is there a role for ondansetron?
Topics: Animals; Antipruritics; Central Nervous System; Evidence-Based Medicine; Fatigue; Humans; Liver Dise | 2008 |
[Cholestatic pruritus--pathophysiology and therapy with special reference to treatment with 5-hydroxytryptamine subtype 3 receptor antagonists].
Topics: Adult; Child; Cholestasis, Intrahepatic; Female; Humans; Indoles; Male; Nociceptors; Ondansetron; Pr | 1995 |
Ondansetron. A review of its pharmacology and preliminary clinical findings in novel applications.
Topics: Animals; Antiemetics; Brain; Colonic Diseases, Functional; Digestive System; Drug Interactions; Drug | 1996 |
Pruritus.
Topics: Acupuncture; Administration, Topical; Anti-Inflammatory Agents; Antipruritics; Combined Modality The | 2001 |
34 trials available for ondansetron and Pruritus
| Article | Year |
|---|---|
Intravenous ondansetron reduced nausea but not pruritus following intrathecal morphine in children: Interim results of a randomized, double-blinded, placebo-control trial.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Child; Double-Blind Method; Female; Humans; Injections, | 2022 |
Ondansetron versus ondansetron with dexamethasone to prevent intrathecal-morphine pruritus for caesarean patients: randomised double-blind trial.
Topics: Adult; Antipruritics; Cesarean Section; Dexamethasone; Double-Blind Method; Drug Therapy, Combinatio | 2021 |
Prevention versus treatment of intrathecal morphine-induced pruritus with ondansetron.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Antipruritics; Cesarean Section; Double-Blind Method; | 2014 |
Comparison of pregabalin with ondansetron in treatment of uraemic pruritus in dialysis patients: a prospective, randomized, double-blind study.
Topics: Adult; Aged; Analgesics; Antipruritics; Double-Blind Method; Drug Therapy, Combination; Female; gamm | 2015 |
Prophylactic administration of ondansetron in prevention of intrathecal morphine-induced pruritus and post-operative nausea and vomiting in patients undergoing caesarean section.
Topics: Adult; Analgesics, Opioid; Antiemetics; Cesarean Section; Double-Blind Method; Female; Humans; Morph | 2015 |
Prophylactic administration of ondansetron in prevention of intrathecal morphine-induced pruritus and post-operative nausea and vomiting in patients undergoing caesarean section.
Topics: Adult; Analgesics, Opioid; Antiemetics; Cesarean Section; Double-Blind Method; Female; Humans; Morph | 2015 |
Prophylactic administration of ondansetron in prevention of intrathecal morphine-induced pruritus and post-operative nausea and vomiting in patients undergoing caesarean section.
Topics: Adult; Analgesics, Opioid; Antiemetics; Cesarean Section; Double-Blind Method; Female; Humans; Morph | 2015 |
Prophylactic administration of ondansetron in prevention of intrathecal morphine-induced pruritus and post-operative nausea and vomiting in patients undergoing caesarean section.
Topics: Adult; Analgesics, Opioid; Antiemetics; Cesarean Section; Double-Blind Method; Female; Humans; Morph | 2015 |
A randomized controlled trial of pentazocine versus ondansetron for the treatment of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Antipruritics; Cesarean Section; Double-Blind Met | 2009 |
Reduction of severity of pruritus after elective caesarean section under spinal anaesthesia with subarachnoid morphine: a randomised comparison of prophylactic granisetron and ondansetron.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Double-Bli | 2010 |
Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery.
Topics: Adult; Cesarean Section; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Hum | 2010 |
Prophylactic ondansetron reduces the incidence of intrathecal fentanyl-induced pruritus.
Topics: Adult; Aged; Anesthesia, Spinal; Double-Blind Method; Female; Fentanyl; Humans; Incidence; Injection | 2002 |
A randomized, placebo-controlled, double-blind trial of ondansetron in renal itch.
Topics: Antipruritics; Double-Blind Method; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Onda | 2003 |
Plasma serotonin and histamine levels in hemodialysis-related pruritus are not significantly influenced by 5-HT3 receptor blocker and antihistaminic therapy.
Topics: Adult; Cetirizine; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Indoles; Male; | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
A comparison of dexamethasone, ondansetron, and dexamethasone plus ondansetron as prophylactic antiemetic and antipruritic therapy in patients receiving intrathecal morphine for major orthopedic surgery.
Topics: Aged; Analgesics, Opioid; Antiemetics; Dexamethasone; Double-Blind Method; Drug Combinations; Female | 2003 |
Ondansetron does not prevent pruritus induced by low-dose intrathecal fentanyl.
Topics: Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Antiprur | 2003 |
Prophylactic iv ondansetron reduces nausea, vomiting and pruritus following epidural morphine for postoperative pain control.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Antiemetics; Double-Blind Method; Female; Humans; H | 2003 |
Antipruritic effects of two different 5-HT3 receptor antagonists and an antihistamine in haemodialysis patients.
Topics: Adult; Aged; Antipruritics; Cetirizine; Female; Histamine; Histamine H1 Antagonists; Humans; Indoles | 2004 |
Intrathecal fentanyl-induced pruritus during labour: the effect of prophylactic ondansetron.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Humans; In | 2004 |
A controlled trial of ondansetron in the pruritus of cholestasis.
Topics: Adult; Aged; Aged, 80 and over; Antipruritics; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary | 2005 |
Ondansetron, orally disintegrating tablets versus intravenous injection for prevention of intrathecal morphine-induced nausea, vomiting, and pruritus in young males.
Topics: Administration, Oral; Adult; Humans; Injections, Intravenous; Injections, Spinal; Male; Morphine; On | 2005 |
Prophylactic intravenous ondansetron and dolasetron in intrathecal morphine-induced pruritus: a randomized, double-blinded, placebo-controlled study.
Topics: Adult; Aged; Analgesics, Opioid; Double-Blind Method; Female; Humans; Indoles; Injections, Spinal; M | 2005 |
Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-S | 2006 |
Does ondansetron or granisetron prevent subarachnoid morphine-induced pruritus after cesarean delivery?
Topics: Adult; Antipruritics; Cesarean Section; Female; Granisetron; Humans; Injections, Spinal; Morphine; O | 2007 |
Lornoxicam and ondansetron for the prevention of intrathecal fentanyl-induced pruritus.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipruritics; Apgar Score; Cesarean Section; Double | 2007 |
Epidural ondansetron is more effective to prevent postoperative pruritus and nausea than intravenous ondansetron in elective cesarean delivery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Animals; Antiemetics; Cesarean Section; Female; Hum | 2007 |
Ondansetron and pruritus in chronic liver disease: a controlled study.
Topics: Adolescent; Adult; Aged; Antipruritics; Chronic Disease; Double-Blind Method; Female; Humans; Liver | 2007 |
Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron.
Topics: Adult; Aged; Cholangitis, Sclerosing; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Male; M | 1995 |
Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Female; Histamine; Humans; Kidney Failure, Chr | 1998 |
Treatment of pruritus in chronic liver disease with the 5-hydroxytryptamine receptor type 3 antagonist ondansetron: a randomized, placebo-controlled, double-blind cross-over trial.
Topics: Administration, Oral; Adult; Aged; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; | 1998 |
Ondansetron is effective to treat spinal or epidural morphine-induced pruritus.
Topics: Analgesics, Opioid; Antipruritics; Double-Blind Method; Humans; Injections, Epidural; Injections, In | 1999 |
Management of opioid-induced pruritus: a role for 5-HT3 antagonists?
Topics: Adolescent; Adult; Aged; Alfentanil; Analgesics, Opioid; Double-Blind Method; Drug Eruptions; Female | 1999 |
Opioid-induced pruritus: repeated vs single dose ondansetron administration in preventing pruritus after intrathecal morphine.
Topics: Adult; Aged; Analgesics, Opioid; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; O | 1999 |
Ondansetron therapy for uremic pruritus in hemodialysis patients.
Topics: Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Ondansetron | 2000 |
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca | 2000 |
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca | 2000 |
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca | 2000 |
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca | 2000 |
Prophylactic ondansetron is effective in the treatment of nausea and vomiting but not on pruritus after cesarean delivery with intrathecal sufentanil-morphine.
Topics: Adult; Anesthesia, Obstetrical; Antiemetics; Bupivacaine; Cesarean Section; Double-Blind Method; Fem | 2002 |
23 other studies available for ondansetron and Pruritus
| Article | Year |
|---|---|
5-HT3 receptors antagonists reduce serotonin-induced scratching in mice.
Topics: Animals; Antipruritics; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; | 2015 |
Granisetron or ondansetron for prevention of subarachnoid morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Antiemetics; Antipruritics; Cesarean Section; Female; Granisetron; Humans | 2010 |
[Opioid-induced pruritus].
Topics: Analgesics, Opioid; Antipruritics; Humans; Injections, Spinal; Naloxone; Ondansetron; Pruritus; Qual | 2012 |
The effect of ondansetron and intrathecal diamorphine on length of stay after caesarean section: an impact audit cycle.
Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Antiemetics; Cesarean Section; Female; Heroin; H | 2013 |
[Pathogenesis and treatment of pruritus in patients with cholestasis].
Topics: Brain; Cholestasis; Cholestyramine Resin; Dronabinol; Enzyme Induction; Humans; Liver; Narcotic Anta | 2003 |
Ondansetron for prevention of intrathecal opioids-induced pruritus, nausea and vomiting after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Antiemetics; Cesarean Section; Female; Humans; Morphine; Ondansetron; Pos | 2004 |
Ondansetron for paediatric uraemic pruritus: a case report.
Topics: Adolescent; Antipruritics; Female; Humans; Kidney Failure, Chronic; Ondansetron; Peritoneal Dialysis | 2004 |
Cholestasis of pregnancy, pruritus and 5-hydroxytryptamine 3 receptor antagonists.
Topics: Cesarean Section; Cholestasis, Intrahepatic; Dose-Response Relationship, Drug; Female; Follow-Up Stu | 2004 |
Life-threatening blood loss from scratching provoked by pruritus in the bulky perineal nevocytoma variant of giant congenital melanocytic nevus in a child.
Topics: Anal Canal; Anemia; Antipruritics; Child, Preschool; Female; Hemorrhage; Humans; Nevus, Pigmented; O | 2005 |
[Therapy of pruritus associated with skin diseases with the serotonin receptor antagonist ondansetron].
Topics: Administration, Oral; Aged; Aged, 80 and over; Antipruritics; Dermatitis, Atopic; Eczema; Female; Fo | 2003 |
Ondansetron treatment in a child presenting with chronic intractable pruritus.
Topics: Antipruritics; Child; Chronic Disease; Humans; Male; Ondansetron; Pruritus | 2006 |
[Ondansetron. A satisfactory treatment for refractory palmo-plantar pruritus].
Topics: Adult; Female; Foot Dermatoses; Hand Dermatoses; Humans; Ondansetron; Pruritus; Remission Induction; | 2006 |
Improvement of cholestatic pruritus by ondansetron.
Topics: Cholestasis; Female; Humans; Middle Aged; Ondansetron; Pruritus | 1993 |
Ondansetron for pruritus due to cholestasis.
Topics: Cholestasis; Female; Humans; Male; Ondansetron; Pruritus | 1994 |
Treatment of pruritus: a new indication for serotonin type 3 receptor antagonists.
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Ondansetron; Pruritus | 1993 |
Ondansetron for the treatment of pruritus after spinal opioids.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Female; Humans; Morphine; Ondansetron | 1996 |
5HT3 receptor antagonists and pruritus due to cholestasis.
Topics: Aged; Breast Neoplasms; Cholestasis; Female; Granisetron; Humans; Liver Neoplasms; Ondansetron; Prur | 1996 |
The use of ondansetron to treat pruritus associated with intrathecal morphine in two paediatric patients.
Topics: Adolescent; Analgesia; Analgesics, Opioid; Child, Preschool; Female; Humans; Injections, Intravenous | 1996 |
Ondansetron for pruritus in child with chronic cholestasis.
Topics: Alagille Syndrome; Child, Preschool; Cholestasis; Chronic Disease; Female; Humans; Ondansetron; Prur | 1996 |
Successful treatment of intractable palmoplantar pruritus with ondansetron.
Topics: Administration, Oral; Female; Follow-Up Studies; Foot Dermatoses; Hand Dermatoses; Humans; Middle Ag | 1998 |
[Ondansetron for cholestatic pruritus].
Topics: Aged; Cholestasis; Humans; Male; Ondansetron; Pruritus; Serotonin Antagonists | 1998 |
Antipruritic potency of serotonin type 3 (5-HT3) receptor antagonists--a reply.
Topics: Foot Dermatoses; Hand Dermatoses; Humans; Ondansetron; Pruritus; Serotonin Antagonists | 1999 |
[Ondansetron in the treatment of the pruritus associated with the spinal infusion of opiates].
Topics: Adjuvants, Anesthesia; Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthesia, Spinal; Fentanyl; | 2000 |