griseofulvin and Pruritus

Topics: Animals; Antifungal Agents; Arm; Child; Diagnosis, Differential; Erythema; Exanthema; Female; Griseofulvin; Guinea Pigs; Humans; Pets; Pruritus; Thorax; Tinea

Topics: Antifungal Agents; Child, Preschool; Dermatomycoses; Fluorescence; Griseofulvin; Humans; Light; Male; Pruritus

Topics: Antifungal Agents; Dermatomycoses; Diagnosis, Differential; Fluorescence; Griseofulvin; Humans; Light; Microsporum; Pruritus; Skin

We discuss a patient with central centrifugal cicatricial alopecia (CCCA) who developed severe scalp pruritus that was initially attributed to the cicatricial alopecia and ultimately diagnosed as tinea capitis. The rarity of severe pruritus in CCCA should prompt a search for a fungal infection in these patients.

Topics: Adult; Aged; Alopecia; Antifungal Agents; Arthritis, Rheumatoid; Child; Child, Preschool; Cicatrix; Drug Therapy, Combination; Female; Griseofulvin; Humans; Immunocompromised Host; Immunosuppressive Agents; Middle Aged; Naphthalenes; Pruritus; Terbinafine; Tinea Capitis

The aim was to describe the mycological and clinical data in children diagnosed with tinea capitis in a hospital setting in Stockholm. Information concerning demography, symptoms, mycology and treatment were obtained, retrospectively, from medical records of all children up to 15 years of age diagnosed with tinea capitis during two 3-year periods, 1989--1991 and 1999--2001, at the Pediatric Dermatology Unit of the Karolinska Hospital in Stockholm. Between 1989 and 1991, five children were diagnosed with tinea capitis. Between 1999 and 2001, there were 92 children, the vast majority (86%) being of foreign extraction, mostly African (83%). Trichophyton violaceum was the most prevalent pathogen, affecting 68% of the children. Of the anthropophilic infections, 62% were linked to relatives. In 71% of all positive cultures, microscopy was positive. The most common clinical findings were scaling of the scalp (80%), itching (54%) and patches of alopecia (52%). The treatment consisted of the oral antimycotics terbinafine (n = 48) or griseofulvin (n = 49). During the last decade there has been an increase in tinea capitis in Stockholm, most commonly caused by Trichophyton violaceum, corresponding with the increased immigration from Africa. Spread within the family seems to be of importance, and family members are preferably screened in an effort to prevent continued transmission. It is important to bear the diagnosis of tinea capitis in mind, especially as, untreated, some cases can develop permanent alopecia and may also cause further spreading of this infection.

Topics: Adolescent; Alopecia; Antifungal Agents; Child; Child, Preschool; Emigration and Immigration; Family Health; Female; Griseofulvin; Humans; Infant; Infant, Newborn; Male; Naphthalenes; Pruritus; Retrospective Studies; Sweden; Terbinafine; Tinea Capitis; Trichophyton

Diffuse lichen planus, a rare disorder in children, was observed in an 8-year-old boy. Effective therapy in this disease remains a problem and currently relies predominantly on the use of the corticosteroids. The complications attendant with corticosteroid administration in children are discussed and a review of alternate modes of therapy for lichen planus is presented.

Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Child; Griseofulvin; Growth Disorders; Humans; Lichen Planus; Male; Pruritus; PUVA Therapy; Tretinoin; Vitamin A