ofloxacin has been researched along with Pruritus in 5 studies
Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty patients with chronic respiratory infections were randomly assigned to 2 groups to compare the effect of once daily administration of 300 mg each and 3 times daily administration of 600 mg each of ofloxacin (OFLX)." | 6.67 | [Clinical studies of ofloxacin 300 mg once a day administration in chronic respiratory tract infections]. ( Fukuhara, H; Horimoto, S; Inadame, J; Irabu, Y; Kusano, N; Miyagi, M; Nakamura, H; Saito, A; Shigeno, Y; Shimozi, T, 1993) |
| "Vancomycin has been used with increased frequency during the past 15 years and the most common toxicity with this drug is the red man syndrome ." | 3.71 | Uncommon vancomycin-induced side effects. ( Baptista, MI; Da Cunha, CA; Kondo, W; Martins, LT; Rocha, JL, 2002) |
| "The series is part of an ongoing randomised controlled trial assessing rechallenge dosing following TB-associated cutaneous ADR." | 2.77 | Multiple drug hypersensitivity reactions to anti-tuberculosis drugs: five cases in HIV-infected patients. ( Dheda, K; Lehloenya, RJ; Todd, G; Wallace, J, 2012) |
| "Forty patients with chronic respiratory infections were randomly assigned to 2 groups to compare the effect of once daily administration of 300 mg each and 3 times daily administration of 600 mg each of ofloxacin (OFLX)." | 2.67 | [Clinical studies of ofloxacin 300 mg once a day administration in chronic respiratory tract infections]. ( Fukuhara, H; Horimoto, S; Inadame, J; Irabu, Y; Kusano, N; Miyagi, M; Nakamura, H; Saito, A; Shigeno, Y; Shimozi, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Lehloenya, RJ | 1 |
| Wallace, J | 1 |
| Todd, G | 1 |
| Dheda, K | 1 |
| Rocha, JL | 1 |
| Kondo, W | 1 |
| Baptista, MI | 1 |
| Da Cunha, CA | 1 |
| Martins, LT | 1 |
| Fukuhara, H | 1 |
| Kusano, N | 1 |
| Irabu, Y | 1 |
| Shigeno, Y | 1 |
| Saito, A | 1 |
| Nakamura, H | 1 |
| Horimoto, S | 1 |
| Shimozi, T | 1 |
| Miyagi, M | 1 |
| Inadame, J | 1 |
| Drouet, M | 1 |
| Nicolie, B | 1 |
| Mauffret, N | 1 |
2 trials available for ofloxacin and Pruritus
| Article | Year |
|---|---|
Multiple drug hypersensitivity reactions to anti-tuberculosis drugs: five cases in HIV-infected patients.
Topics: Adult; Antitubercular Agents; Coinfection; Drug Eruptions; Drug Hypersensitivity; Edema; Eosinophili | 2012 |
[Clinical studies of ofloxacin 300 mg once a day administration in chronic respiratory tract infections].
Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Blood Urea Nitrogen; Creatinine; Drug Administ | 1993 |
3 other studies available for ofloxacin and Pruritus
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Uncommon vancomycin-induced side effects.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Eosinophilia; Erythema; Female; Fever; Hip Pros | 2002 |
[Unusual clinical form of amoxicillin allergy].
Topics: Amoxicillin; Clarithromycin; Drug Eruptions; Drug Therapy, Combination; Edema; Female; Humans; Methy | 1996 |