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trioxsalen and Pruritus

trioxsalen has been researched along with Pruritus in 1 studies

Trioxsalen: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.
lactone : Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
antipsoriatic : A drug used to treat psoriasis.
trioxsalen : 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis.

Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.

Research Excerpts

ExcerptRelevanceReference
"Good results were achieved in psoriasis with trioxsalen baths and UVA in 92% of 158 patients during initial treatment and in 83% of 139 patients during long-term treatment."7.66Long-term local trioxsalen photochemotherapy in psoriasis. ( Hannuksela, M; Karvonen, J; Väätäinen, N, 1981)
"Good results were achieved in psoriasis with trioxsalen baths and UVA in 92% of 158 patients during initial treatment and in 83% of 139 patients during long-term treatment."3.66Long-term local trioxsalen photochemotherapy in psoriasis. ( Hannuksela, M; Karvonen, J; Väätäinen, N, 1981)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Väätäinen, N1
Hannuksela, M1
Karvonen, J1

Other Studies

1 other study available for trioxsalen and Pruritus

ArticleYear
Long-term local trioxsalen photochemotherapy in psoriasis.
    Dermatologica, 1981, Volume: 163, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Aged; Baths; Burns; Female; Furocoumarins; Humans; Male;

1981