Page last updated: 2024-10-30

leflunomide and Pruritus

leflunomide has been researched along with Pruritus in 4 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.

Research Excerpts

ExcerptRelevanceReference
"Leflunomide is a disease-modifying antirheumatic drug used for treating rheumatoid arthritis (RA)."7.74Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients. ( Bohanec Grabar, P; Dolzan, V; Logar, D; Rozman, B; Suput, D; Tomsic, M, 2008)
"Leflunomide is a disease-modifying antirheumatic drug used for treating rheumatoid arthritis (RA)."3.74Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients. ( Bohanec Grabar, P; Dolzan, V; Logar, D; Rozman, B; Suput, D; Tomsic, M, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Kassar, R1
Chang, J1
Chan, AW1
Lilly, LB1
Al Habeeb, A1
Rotstein, C1
Savoia, F1
Gaddoni, G1
Casadio, C1
Spadola, G1
Patrizi, A1
Giacomini, F1
Aldi, M1
Bohanec Grabar, P1
Rozman, B1
Tomsic, M1
Suput, D1
Logar, D1
Dolzan, V1

Other Studies

4 other studies available for leflunomide and Pruritus

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Leflunomide for the treatment of trichodysplasia spinulosa in a liver transplant recipient.
    Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Cyclosporine; Diagnosis, Differential; Hair Diseases; Hair Follicle;

2017
A case of eczematous and vesicular dermatitis during anti-TNFalpha therapy for rheumatoid arthritis.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2011, Volume: 146, Issue:4

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnostic Errors; Drug Eruptions; Drug Synergis

2011
Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients.
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:9

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cytochrome P-450 CYP1A2; Diarrhea; Dose-Response

2008