leflunomide has been researched along with Pruritus in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide is a disease-modifying antirheumatic drug used for treating rheumatoid arthritis (RA)." | 7.74 | Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients. ( Bohanec Grabar, P; Dolzan, V; Logar, D; Rozman, B; Suput, D; Tomsic, M, 2008) |
| "Leflunomide is a disease-modifying antirheumatic drug used for treating rheumatoid arthritis (RA)." | 3.74 | Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients. ( Bohanec Grabar, P; Dolzan, V; Logar, D; Rozman, B; Suput, D; Tomsic, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Kassar, R | 1 |
| Chang, J | 1 |
| Chan, AW | 1 |
| Lilly, LB | 1 |
| Al Habeeb, A | 1 |
| Rotstein, C | 1 |
| Savoia, F | 1 |
| Gaddoni, G | 1 |
| Casadio, C | 1 |
| Spadola, G | 1 |
| Patrizi, A | 1 |
| Giacomini, F | 1 |
| Aldi, M | 1 |
| Bohanec Grabar, P | 1 |
| Rozman, B | 1 |
| Tomsic, M | 1 |
| Suput, D | 1 |
| Logar, D | 1 |
| Dolzan, V | 1 |
4 other studies available for leflunomide and Pruritus
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Leflunomide for the treatment of trichodysplasia spinulosa in a liver transplant recipient.
Topics: Adrenal Cortex Hormones; Adult; Cyclosporine; Diagnosis, Differential; Hair Diseases; Hair Follicle; | 2017 |
A case of eczematous and vesicular dermatitis during anti-TNFalpha therapy for rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnostic Errors; Drug Eruptions; Drug Synergis | 2011 |
Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cytochrome P-450 CYP1A2; Diarrhea; Dose-Response | 2008 |