Page last updated: 2024-10-25

clonidine and Pruritus

clonidine has been researched along with Pruritus in 10 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.

Research Excerpts

ExcerptRelevanceReference
"The addition of clonidine to epidural levobupivacaine and sufentanil for patient-controlled epidural analgesia in labour improved analgesia, reduced the supplementation rate and reduced pruritus without improvement in maternal satisfaction."5.14Effects of a continuous low-dose clonidine epidural regimen on pain, satisfaction and adverse events during labour: a randomized, double-blind, placebo-controlled trial. ( Aubrun, F; Bouret, C; Broisin, F; Charpiat, B; Clement, HJ; Derre, E; Huissoud, C; Lopez, F; Pignal, C; Schoeffler, M; Viale, JP; Wallet, F, 2010)
"Clonidine levels were undetectable in maternal serum."2.69Intrathecal clonidine combined with sufentanil for labor analgesia. ( De Kock, M; Fanard, L; Gautier, PE; Hody, JL; Van Steenberge, A, 1998)
"Mosquito allergy of the hind paw elicited biting, an itch-related response, in sensitized mice."1.37Tonic inhibition of allergic itch signaling by the descending noradrenergic system in mice. ( Andoh, T; Gotoh, Y; Kuraishi, Y; Omori, Y, 2011)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Andoh, T3
Suzuki, K1
Konno, M1
Tsuneyama, K1
Kuraishi, Y3
Carvalho, FA1
Tenório, SB1
Shiohara, FT1
Maia, LR1
Mota, A1
Dewandre, PY1
Decurninge, V1
Bonhomme, V1
Hans, P1
Brichant, JF1
Wallet, F1
Clement, HJ1
Bouret, C1
Lopez, F1
Broisin, F1
Pignal, C1
Schoeffler, M1
Derre, E1
Charpiat, B1
Huissoud, C1
Aubrun, F1
Viale, JP1
Gotoh, Y2
Omori, Y1
Schwartz, J1
Rosenfeld, V1
Gautier, PE1
De Kock, M1
Fanard, L1
Van Steenberge, A1
Hody, JL1
Camacho-Martínez, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Epidural Analgesia During Labour. Impact of Clonidine Addition to Levobupivacaine and Sufentanil[NCT00437996]Phase 385 participants (Actual)Interventional2007-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for clonidine and Pruritus

ArticleYear
Randomized study of postcesarean analgesia with intrathecal morphine alone or combined with clonidine.
    Journal of clinical anesthesia, 2016, Volume: 33

    Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Cesarean Section; Clonidine; Double-Blind Meth

2016
Side effects of the addition of clonidine 75 microg or sufentanil 5 microg to 0.2% ropivacaine for labour epidural analgesia.
    International journal of obstetric anesthesia, 2010, Volume: 19, Issue:2

    Topics: Adult; Amides; Analgesia, Epidural; Analgesics; Anesthesia, Obstetrical; Anesthetics, Local; Clonidi

2010
Effects of a continuous low-dose clonidine epidural regimen on pain, satisfaction and adverse events during labour: a randomized, double-blind, placebo-controlled trial.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:5

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; An

2010
Intrathecal clonidine combined with sufentanil for labor analgesia.
    Anesthesiology, 1998, Volume: 88, Issue:3

    Topics: Adult; Anesthetics; Clonidine; Drug Synergism; Female; Humans; Injections, Spinal; Labor, Obstetric;

1998

Other Studies

6 other studies available for clonidine and Pruritus

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Pharmacological Characterization of a Novel Mouse Model of Cholestatic Pruritus.
    Biological & pharmaceutical bulletin, 2020, Volume: 43, Issue:7

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic

2020
Clonidine inhibits itch-related response through stimulation of α(2)-adrenoceptors in the spinal cord in mice.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Antipruritics; Behavior, Animal; Clonidine; Inject

2011
Tonic inhibition of allergic itch signaling by the descending noradrenergic system in mice.
    Journal of pharmacological sciences, 2011, Volume: 115, Issue:3

    Topics: Animals; Bites and Stings; Clonidine; Culicidae; Histamine Antagonists; Hypersensitivity; Injections

2011
Clonidine for painful diabetic-uremic leg cramps and pruritus--a case report.
    Angiology, 1993, Volume: 44, Issue:12

    Topics: Aged; Clonidine; Diabetes Mellitus, Type 2; Humans; Leg; Male; Muscle Cramp; Pruritus; Uremia

1993
Localized trichorrhexis nodosa.
    Journal of the American Academy of Dermatology, 1989, Volume: 20, Issue:4

    Topics: Adult; Clonidine; Face; Female; Hair Diseases; Humans; Male; Metronidazole; Pruritus; Pruritus Vulva

1989