fluprednidene acetate

Description

fluprednidene acetate: has anti-inflammatory & anti-allergic properties; minor descriptor (75-83); on-line & Index Medicus search PREGNADIENETRIOLS (75-83); RN given refers to (11beta)-isomer; structure [MeSH]

Cross-References

ID Source	ID
PubMed CID	13156354
MeSH ID	M0262508

Synonyms (7)

Synonym
fluprednidene acetate
1255-35-2
FT-0668758
[2-(9-fluoro-11,17-dihydroxy-10,13-dimethyl-16-methylidene-3-oxo-7,8,11,12,14,15-hexahydro-6h-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] acetate
[2-[(8s,9r,10s,13s,14s,17r)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-16-methylidene-3-oxo-7,8,11,12,14,15-hexahydro-6h-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
DTXSID40859610
9-fluoro-11,17-dihydroxy-16-methylidene-3,20-dioxopregna-1,4-dien-21-yl acetate

Research

Studies (8)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	5 (62.50)	18.7374
1990's	2 (25.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (12.50)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	3 (37.50%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	1 (12.50%)	4.05%
Observational	0 (0.00%)	0.25%
Other	4 (50.00%)	84.16%

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2010's
croton oil	2	N-acyl-hexosamine		1985	1986	38.5	medium	0	2	0	0
miconazole	3	dichlorobenzene; ether; imidazoles		1994	2020	21.0	high	1	0	2	1
fluocinolone acetonide	1	11beta-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; cyclic ketal; fluorinated steroid; glucocorticoid; organic heteropentacyclic compound; primary alpha-hydroxy ketone	anti-inflammatory drug; antipruritic drug	1986	1986	38.0	low	0	1	0	0
methyl nicotinate	1	aromatic carboxylic acid; pyridines		1986	1986	38.0	low	0	1	0	0
dodecyl sulfate	1	alkyl sulfate		1986	1986	38.0	low	0	1	0	0
betamethasone	2	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; fluorinated steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	anti-asthmatic agent; anti-inflammatory drug; immunosuppressive agent	1983	1985	40.0	medium	1	2	0	0
betamethasone valerate	2	11beta-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; fluorinated steroid; primary alpha-hydroxy ketone; steroid ester	anti-inflammatory drug	1985	1986	38.5	medium	0	2	0	0
sodium dodecyl sulfate	1	organic sodium salt	detergent; protein denaturant	1986	1986	38.0	low	0	1	0	0
clobetasol	1	11beta-hydroxy steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 3-oxo-Delta(1),Delta(4)-steroid; chlorinated steroid; fluorinated steroid; glucocorticoid; tertiary alpha-hydroxy ketone	anti-inflammatory drug; SMO receptor agonist	1983	1983	41.0	low	1	1	0	0

Condition	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2010's
Athlete's Foot	1	2020	2020	4.0	low	0	0	0	1
Atrophy	1	1989	1989	35.0	low	1	1	0	0
Bacterial Skin Diseases	1	1995	1995	29.0	low	1	0	1	0
Chronic Disease	1	1983	1983	41.0	low	1	1	0	0
Chronic Illness	1	1983	1983	41.0	low	1	1	0	0
Contact Dermatitis	1	1986	1986	38.0	low	0	1	0	0
Dermatitis	1	1985	1985	39.0	low	0	1	0	0
Dermatitis, Atopic	1	1983	1983	41.0	low	1	1	0	0
Dermatitis, Contact	1	1986	1986	38.0	low	0	1	0	0
Dermatitis, Eczematous	2	1983	1989	38.0	low	2	2	0	0
Dermatomycoses	1	1995	1995	29.0	low	1	0	1	0
Eczema	2	1983	1989	38.0	low	2	2	0	0
Eczema, Atopic	1	1983	1983	41.0	low	1	1	0	0
Erythema	1	1985	1985	39.0	low	0	1	0	0
Hand Dermatoses	1	1983	1983	41.0	low	1	1	0	0
Hand Dermatosis	1	1983	1983	41.0	low	1	1	0	0
Inflammation	2	1983	1995	35.0	low	1	1	1	0
Innate Inflammatory Response	2	1983	1995	35.0	low	1	1	1	0
Itching	1	2020	2020	4.0	low	0	0	0	1
Pruritus	1	2020	2020	4.0	low	0	0	0	1
Skin Diseases, Bacterial	1	1995	1995	29.0	low	1	0	1	0
Tinea Pedis	1	2020	2020	4.0	low	0	0	0	1