Page last updated: 2024-10-29

ketanserin and Pruritus

ketanserin has been researched along with Pruritus in 5 studies

Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.

Research Excerpts

ExcerptRelevanceReference
"SR141716A dose- and age-dependently suppressed food and water intake and body weight gain and elicited head scratching, with the most potent effects observed in P18 and P28 rats."7.75Age-dependent effects of the cannabinoid CB1 antagonist SR141716A on food intake, body weight change, and pruritus in rats. ( Lefever, TW; Rawls, SM; Walker, EA; Ward, SJ; Whiteside, GT, 2009)
"SR141716A dose- and age-dependently suppressed food and water intake and body weight gain and elicited head scratching, with the most potent effects observed in P18 and P28 rats."3.75Age-dependent effects of the cannabinoid CB1 antagonist SR141716A on food intake, body weight change, and pruritus in rats. ( Lefever, TW; Rawls, SM; Walker, EA; Ward, SJ; Whiteside, GT, 2009)
"In a study on the dose-response relationship for longwave UVA (UVA1; 340-400 nm) carcinogenesis in hairless mice scratch marks appeared after months of daily exposure as an unwanted side effect."1.30Chronic UVA (365-nm) irradiation induced scratching in hairless mice: dose-time dependency and the effect of ketanserin. ( de Gruijl, FR; de Laat, JM; Groenendijk, M; Seité, S; van Vloten, WA, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Zhu, Y1
Peng, C1
Xu, JG1
Liu, YX1
Zhu, QG1
Liu, JY1
Li, FQ1
Wu, JH1
Hu, JH1
Ward, SJ1
Lefever, TW1
Rawls, SM1
Whiteside, GT1
Walker, EA1
Akiyama, T1
Carstens, IM1
Carstens, E1
de Laat, JM1
Seité, S1
Groenendijk, M1
van Vloten, WA1
de Gruijl, FR1

Other Studies

5 other studies available for ketanserin and Pruritus

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Participation of proteinase-activated receptor-2 in passive cutaneous anaphylaxis-induced scratching behavior and the inhibitory effect of tacrolimus.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antipruritics; Behavior, Animal; Cetirizine; Dose-Response Relation

2009
Age-dependent effects of the cannabinoid CB1 antagonist SR141716A on food intake, body weight change, and pruritus in rats.
    Psychopharmacology, 2009, Volume: 206, Issue:1

    Topics: Age Factors; Animals; Brain; Dose-Response Relationship, Drug; Drinking; Eating; Feeding Behavior; K

2009
Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch.
    Pain, 2010, Volume: 151, Issue:2

    Topics: Animals; Antibodies; Behavior, Animal; Calcium; Capsaicin; Disease Models, Animal; Ganglia, Spinal;

2010
Chronic UVA (365-nm) irradiation induced scratching in hairless mice: dose-time dependency and the effect of ketanserin.
    Experimental dermatology, 1997, Volume: 6, Issue:6

    Topics: Animals; Biopsy; Cell Count; Dose-Response Relationship, Radiation; Female; Ketanserin; Male; Mast C

1997