Potassium voltage-gated channel subfamily V member 2

A voltage-gated potassium channel KCNV2 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q8TDN2]

Voltage-gated potassium channel subunit Kv8.2

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
N-(2-aminoethyl)-5-chloro-1-naphthalenesulfonamide	Homo sapiens (human)	IC50	54,954,100,000.0000	1	1

This protein enables 2 target(s):

Target	Category	Definition
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
voltage-gated potassium channel activity	molecular function	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. [GOC:mtg_transport, ISBN:0815340729]

This protein is located in 1 target(s):

Target	Category	Definition
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

This protein is active in 1 target(s):

Target	Category	Definition
membrane	cellular component	A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]

This protein is part of 1 target(s):

Target	Category	Definition
voltage-gated potassium channel complex	cellular component	A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential. [GOC:mah]

This protein is involved in 3 target(s):

Target	Category	Definition
protein homooligomerization	biological process	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. [GOC:ai]
action potential	biological process	A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities. [GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8]
potassium ion transmembrane transport	biological process	A process in which a potassium ion is transported from one side of a membrane to the other. [GOC:mah]