mianserin has been researched along with Pruritus in 11 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pruritus was significantly more frequent in the placebo group compared with the mirtazapine group (75% vs 52%, respectively; P=0." | 9.13 | Prophylactic mirtazapine reduces intrathecal morphine-induced pruritus. ( Chang, FL; Ho, ST; Huang, ST; Lee, CH; Sheen, MJ; Tsung, YC, 2008) |
| "Pruritus is a debilitating symptom that can be associated with cutaneous involvement by an underlying malignancy." | 5.43 | Effective use of mirtazapine for refractory pruritus associated with carcinoma en cuirasse. ( Carlberg, VM; Girouard, SD; Lee, JJ; Mostaghimi, A, 2016) |
| "Pruritus is a relatively rare but distressing symptom associated with cholestasis, renal failure, and malignancies." | 5.32 | Mirtazapine for pruritus. ( Andresen, S; Davis, MP; Frandsen, JL; Taylor, S; Walsh, D, 2003) |
| "Mirtazapine is a safe medication without serious side effects and may be an effective alternative for the treatment of nocturnal pruritus." | 5.32 | Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: a pilot study. ( Hundley, JL; Yosipovitch, G, 2004) |
| "Pruritus was significantly more frequent in the placebo group compared with the mirtazapine group (75% vs 52%, respectively; P=0." | 5.13 | Prophylactic mirtazapine reduces intrathecal morphine-induced pruritus. ( Chang, FL; Ho, ST; Huang, ST; Lee, CH; Sheen, MJ; Tsung, YC, 2008) |
| "Psoriasis is a common chronic inflammatory skin disease observed in about 1-3% of the general population." | 2.53 | Itch in Psoriasis Management. ( Reich, A; Szepietowski, JC, 2016) |
| "In cases of malignancy that are refractive to treatment, other therapies have been found to be effective for paraneoplastic itch, including selective serotonin reuptake inhibitors, mirtazapine, gabapentin, thalidomide, opioids, aprepitant, and histone deacetylase inhibitors." | 2.53 | Paraneoplastic Itch Management. ( Rowe, B; Yosipovitch, G, 2016) |
| "Pruritus is a debilitating symptom that can be associated with cutaneous involvement by an underlying malignancy." | 1.43 | Effective use of mirtazapine for refractory pruritus associated with carcinoma en cuirasse. ( Carlberg, VM; Girouard, SD; Lee, JJ; Mostaghimi, A, 2016) |
| "Pruritus is a relatively rare but distressing symptom associated with cholestasis, renal failure, and malignancies." | 1.32 | Mirtazapine for pruritus. ( Andresen, S; Davis, MP; Frandsen, JL; Taylor, S; Walsh, D, 2003) |
| "Mirtazapine is a safe medication without serious side effects and may be an effective alternative for the treatment of nocturnal pruritus." | 1.32 | Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: a pilot study. ( Hundley, JL; Yosipovitch, G, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Lee, HG | 1 |
| Grossman, SK | 1 |
| Valdes-Rodriguez, R | 1 |
| Berenato, F | 1 |
| Korbutov, J | 1 |
| Chan, YH | 1 |
| Lavery, MJ | 1 |
| Yosipovitch, G | 5 |
| Bernhard, JD | 1 |
| Lee, JJ | 1 |
| Girouard, SD | 1 |
| Carlberg, VM | 1 |
| Mostaghimi, A | 1 |
| Szepietowski, JC | 1 |
| Reich, A | 1 |
| Rowe, B | 1 |
| Sheen, MJ | 1 |
| Ho, ST | 1 |
| Lee, CH | 1 |
| Tsung, YC | 1 |
| Chang, FL | 1 |
| Huang, ST | 1 |
| Davis, MP | 1 |
| Frandsen, JL | 1 |
| Walsh, D | 1 |
| Andresen, S | 1 |
| Taylor, S | 1 |
| Hundley, JL | 1 |
| Dawn, A | 1 |
| Demierre, MF | 1 |
| Taverna, J | 1 |
4 reviews available for mianserin and Pruritus
| Article | Year |
|---|---|
Clinical practice. Chronic pruritus.
Topics: Amines; Antidepressive Agents, Tricyclic; Behavior Therapy; Chronic Disease; Cyclohexanecarboxylic A | 2013 |
Itch in Psoriasis Management.
Topics: Adaptation, Psychological; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Doxepin; | 2016 |
Paraneoplastic Itch Management.
Topics: Acantholysis; Acanthosis Nigricans; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Apre | 2016 |
Treating itch in psoriasis.
Topics: Administration, Cutaneous; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipr | 2006 |
1 trial available for mianserin and Pruritus
| Article | Year |
|---|---|
Prophylactic mirtazapine reduces intrathecal morphine-induced pruritus.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Double-Blind Method; Female; Histamine H1 Antagonists | 2008 |
6 other studies available for mianserin and Pruritus
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability.
Topics: Aged; Amines; Amitriptyline; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy, | 2017 |
Effective use of mirtazapine for refractory pruritus associated with carcinoma en cuirasse.
Topics: Aged; Antidepressive Agents, Tricyclic; Antipruritics; Carcinoma, Ductal, Breast; Female; Histamine | 2016 |
Mirtazapine for pruritus.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Cholestasis; Female; Histamine H1 Antagon | 2003 |
Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: a pilot study.
Topics: Adolescent; Adrenergic alpha-Antagonists; Antidepressive Agents, Tricyclic; Female; Humans; Mianseri | 2004 |
Mirtazapine and gabapentin for reducing pruritus in cutaneous T-cell lymphoma.
Topics: Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Gabapentin; | 2006 |