Page last updated: 2024-12-06
2-(2',4'-diaminophenoxy)ethanol
Description
2-(2',4'-diaminophenoxy)ethanol, also known as **2-(2,4-diaminophenoxy)ethanol** or **DAPOE**, is a chemical compound that plays a crucial role in research due to its unique properties and applications.
**Properties:**
* **Structure:** DAPOE is a colorless to pale yellow liquid with a molecular formula of C8H12N2O2. It is composed of a phenol ring with two amino groups (NH2) at the 2' and 4' positions, and an ethoxy group (-OCH2CH2OH) attached to the phenol ring.
* **Reactivity:** DAPOE is a highly reactive compound due to the presence of the amino groups, which can participate in various chemical reactions, including condensation, alkylation, and acylation.
* **Solubility:** It is soluble in water and organic solvents, which makes it suitable for various experimental applications.
* **Biological activity:** DAPOE has been found to exhibit biological activity, including antibacterial, antifungal, and antioxidant properties.
**Research Importance:**
DAPOE is important for research in various fields, including:
* **Materials science:** It is used as a precursor in the synthesis of polymers, resins, and other materials with specific properties.
* **Biochemistry:** DAPOE is used as a reagent in enzymatic assays and protein modification studies.
* **Pharmacology:** Its biological activity makes it a promising candidate for developing new drugs, particularly in the areas of antibacterial and antifungal therapies.
* **Environmental science:** DAPOE is studied for its potential use in bioremediation, where it can help remove pollutants from the environment.
* **Organic synthesis:** DAPOE is a versatile building block for the synthesis of complex organic molecules.
**Specific Research Examples:**
* **Polymer synthesis:** DAPOE is used to synthesize polyamides and polyurethanes with improved properties, such as thermal stability and mechanical strength.
* **Antibacterial activity:** Studies have shown that DAPOE exhibits significant antibacterial activity against a broad range of bacteria, including Staphylococcus aureus and Escherichia coli.
* **Antioxidant activity:** DAPOE has been found to scavenge free radicals and protect cells from oxidative damage, suggesting its potential as a therapeutic agent for diseases related to oxidative stress.
**Conclusion:**
2-(2',4'-diaminophenoxy)ethanol is a versatile chemical compound with unique properties that make it valuable in various research areas. Its reactivity, solubility, and biological activity make it a promising candidate for the development of new materials, drugs, and environmental solutions.
2-(2',4'-diaminophenoxy)ethanol: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
PubMed CID | 47933 |
SCHEMBL ID | 35916 |
MeSH ID | M0101568 |
Synonyms (20)
Synonym |
2-(2,4-diaminophenoxy)ethanol |
FT-0655693 |
AKOS006274686 |
ethanol, 2-(2,4-diaminophenoxy)- |
unii-8di56tbp4b |
2-(2',4'-diaminophenoxy)ethanol |
8di56tbp4b , |
2,4-diamino-1-(2-hydroxyethoxy)benzene |
2,4-diaminophenyl .beta.-hydroxyethyl ether |
3-amino-4-(2'-hydroxyethyloxy)aniline |
SCHEMBL35916 |
2-(2',4'-diamino-phenoxy)ethanol |
WCPGNFONICRLCL-UHFFFAOYSA-N |
DTXSID0073619 |
2-(2,4-diaminophenoxy)ethan-1-ol |
F20765 |
2,4-diamino phenoxy ethanol hydrochloride |
mfcd00190137 |
Q27270229 |
PD159030 |
Research Excerpts
Dosage Studied
Research
Studies (14)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 13 (92.86) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (7.14) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 11.61
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 11.61 (24.57) | Research Supply Index | 2.71 (2.92) | Research Growth Index | 4.32 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 1 (7.14%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 13 (92.86%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |