cimetidine has been researched along with Pruritus in 32 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of oral Cimetidine compared to a classic antihistaminic and to a placebo was evaluated, under the double hypothesis of its anti-PTH and anti-pruritus action, in a population of patients recently included in Hemodialysis that were asked about the incidence and intensity of pruritus according to a scored questionnaire made for this purpose." | 9.05 | Dialysis pruritus: effect of cimetidine. ( Aguilera, J; Aubia, J; Garcia, C; LLorach, I; LLorach, M; LLoveras, J; Masramon, J; Rius, E, 1980) |
| " The antipruritic ability of histamine (H1 and H2) antagonists alone and in combination in experimentally induced pruritus has been investigated in 12 normal human volunteers." | 9.04 | The efficacy of histamine antagonists as antipruritics in experimentally induced pruritus. ( Davies, MG; Horton, RJ; Marks, R; Storari, FE, 1979) |
| "We have studied a 50-year-old white man with chronic urticaria and angioedema who has responded to treatment with cimetidine alone for over 2 yr." | 7.67 | Successful treatment of chronic idiopathic urticaria and angioedema with cimetidine alone. ( Farnam, J; Grant, JA; Guernsey, BG; Jorizzo, JL; Petrusa, ER, 1984) |
| "Intravenous cimetidine treatment was prescribed for patients suffering from anaphylaxis, urticaria, pruritus, and contact dermatitis." | 7.67 | Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions. ( Asano, M; Au-Yong, TF; Kimura, S; Mayumi, H; Shimokawa, T; Yayama, T, 1987) |
| "Thirty-four patients with polycythemia vera complicated by pruritus were treated with 900 mg of cimetidine daily for 30 days and their responses to treatment were evaluated." | 7.66 | The use of cimetidine for the treatment of pruritus in polycythemia vera. ( Cooperberg, AA; Donovan, PB; Dresch, C; Goldberg, JD; Najean, Y; Pisciotta, AV; Weick, JK, 1982) |
| "A 34-year-old woman who had had intractable pruritus for 2 years experienced dramatic relief from the symptom under treatment with cimetidine." | 7.66 | [Pruritus in Hodgkin's disease responding to cimetidine]. ( Graf, W; Stäubli, M; Straub, PW, 1981) |
| "Of the 35 patients with pruritus, all 12 receiving diphenhydramine placebo had clinically significant relief compared with six of ten (60%) receiving cimetidine plus placebo (P = ." | 5.07 | Histamine antagonists in the treatment of acute allergic reactions. ( Caravati, EM; Hartsell, SC; Martinez, JC; Runge, JW; Williamson, SG, 1992) |
| "The effect of oral Cimetidine compared to a classic antihistaminic and to a placebo was evaluated, under the double hypothesis of its anti-PTH and anti-pruritus action, in a population of patients recently included in Hemodialysis that were asked about the incidence and intensity of pruritus according to a scored questionnaire made for this purpose." | 5.05 | Dialysis pruritus: effect of cimetidine. ( Aguilera, J; Aubia, J; Garcia, C; LLorach, I; LLorach, M; LLoveras, J; Masramon, J; Rius, E, 1980) |
| " The antipruritic ability of histamine (H1 and H2) antagonists alone and in combination in experimentally induced pruritus has been investigated in 12 normal human volunteers." | 5.04 | The efficacy of histamine antagonists as antipruritics in experimentally induced pruritus. ( Davies, MG; Horton, RJ; Marks, R; Storari, FE, 1979) |
| "We have studied a 50-year-old white man with chronic urticaria and angioedema who has responded to treatment with cimetidine alone for over 2 yr." | 3.67 | Successful treatment of chronic idiopathic urticaria and angioedema with cimetidine alone. ( Farnam, J; Grant, JA; Guernsey, BG; Jorizzo, JL; Petrusa, ER, 1984) |
| "Intravenous cimetidine treatment was prescribed for patients suffering from anaphylaxis, urticaria, pruritus, and contact dermatitis." | 3.67 | Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions. ( Asano, M; Au-Yong, TF; Kimura, S; Mayumi, H; Shimokawa, T; Yayama, T, 1987) |
| "Thirty-four patients with polycythemia vera complicated by pruritus were treated with 900 mg of cimetidine daily for 30 days and their responses to treatment were evaluated." | 3.66 | The use of cimetidine for the treatment of pruritus in polycythemia vera. ( Cooperberg, AA; Donovan, PB; Dresch, C; Goldberg, JD; Najean, Y; Pisciotta, AV; Weick, JK, 1982) |
| "A 34-year-old woman who had had intractable pruritus for 2 years experienced dramatic relief from the symptom under treatment with cimetidine." | 3.66 | [Pruritus in Hodgkin's disease responding to cimetidine]. ( Graf, W; Stäubli, M; Straub, PW, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (81.25) | 18.7374 |
| 1990's | 3 (9.38) | 18.2507 |
| 2000's | 2 (6.25) | 29.6817 |
| 2010's | 1 (3.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Sharma, N | 1 |
| Kuraishi, Y | 1 |
| Ohtsuka, E | 1 |
| Nakano, T | 1 |
| Kawai, S | 1 |
| Andoh, T | 1 |
| Nojima, H | 1 |
| Kamimura, K | 1 |
| Deutsch, PH | 1 |
| Van Stee, EW | 1 |
| Chee, YC | 1 |
| Farnam, J | 1 |
| Grant, JA | 1 |
| Guernsey, BG | 1 |
| Jorizzo, JL | 1 |
| Petrusa, ER | 1 |
| Thiers, B | 1 |
| Weick, JK | 1 |
| Donovan, PB | 1 |
| Najean, Y | 1 |
| Dresch, C | 1 |
| Pisciotta, AV | 1 |
| Cooperberg, AA | 1 |
| Goldberg, JD | 1 |
| Sandhu, BS | 1 |
| Requena, R | 1 |
| Greaves, MW | 1 |
| Davies, MG | 2 |
| Aubia, J | 1 |
| Aguilera, J | 1 |
| LLorach, I | 1 |
| Garcia, C | 1 |
| Rius, E | 1 |
| LLoveras, J | 1 |
| Masramon, J | 1 |
| LLorach, M | 1 |
| Stäubli, M | 1 |
| Graf, W | 1 |
| Straub, PW | 1 |
| Aymard, JP | 1 |
| Lederlin, P | 1 |
| Witz, F | 1 |
| Colomb, JN | 1 |
| Herbeuval, R | 1 |
| Weber, B | 1 |
| Roberts, DL | 1 |
| Aubert, M | 1 |
| Quilicchini, R | 1 |
| Carcassonne, Y | 1 |
| Taillandier, J | 1 |
| Bussone, A | 1 |
| Manigand, G | 1 |
| Inoue, A | 1 |
| Teramae, H | 1 |
| Hisa, T | 1 |
| Taniguchi, S | 1 |
| Chanoki, M | 1 |
| Hamada, T | 1 |
| Renz, C | 1 |
| Lynch, J | 1 |
| Thurn, J | 1 |
| Moss, J | 1 |
| Schapira, DV | 1 |
| Bennett, JM | 1 |
| Harrison, AR | 1 |
| Littenberg, G | 1 |
| Goldstein, L | 1 |
| Kaplowitz, N | 1 |
| Marks, R | 1 |
| Horton, RJ | 2 |
| Storari, FE | 1 |
| Zappacosta, AR | 1 |
| Hauss, D | 1 |
| Easton, P | 1 |
| Galbraith, PR | 1 |
| Hess, CE | 1 |
| Scott, GL | 1 |
| Runge, JW | 1 |
| Martinez, JC | 1 |
| Caravati, EM | 1 |
| Williamson, SG | 1 |
| Hartsell, SC | 1 |
| Massone, L | 1 |
| Pestarino, A | 1 |
| Borghi, S | 1 |
| Isola, V | 1 |
| Gambini, C | 1 |
| Youngchaiyud, U | 1 |
| Aram, H | 1 |
| Mayumi, H | 1 |
| Kimura, S | 1 |
| Asano, M | 1 |
| Shimokawa, T | 1 |
| Au-Yong, TF | 1 |
| Yayama, T | 1 |
| Berild, D | 1 |
| Hasselbalch, H | 1 |
1 review available for cimetidine and Pruritus
| Article | Year |
|---|---|
Cimetidine in dermatology.
Topics: Androgen Antagonists; Animals; Cimetidine; Humans; Immunity, Cellular; Neoplasms; Pruritus; Skin Dis | 1987 |
6 trials available for cimetidine and Pruritus
| Article | Year |
|---|---|
Dialysis pruritus: effect of cimetidine.
Topics: Cimetidine; Guanidines; Humans; Placebos; Pruritus; Renal Dialysis | 1980 |
Histamine release during rapid vancomycin administration.
Topics: Anti-Bacterial Agents; Cimetidine; Diphenhydramine; Double-Blind Method; Drug Hypersensitivity; Exan | 1998 |
Pruritus, cimetidine and polycythemia.
Topics: Cholestasis; Cimetidine; Clinical Trials as Topic; Guanidines; Humans; Pruritus | 1979 |
The efficacy of histamine antagonists as antipruritics in experimentally induced pruritus.
Topics: Adult; Chlorpheniramine; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Co | 1979 |
Histamine antagonists in the treatment of acute allergic reactions.
Topics: Adult; Anaphylaxis; Blood Pressure; Cimetidine; Diphenhydramine; Double-Blind Method; Drug Therapy, | 1992 |
Comparison of the efficacy of four antihistamines in chronic urticaria.
Topics: Adolescent; Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clemastine; Double-Blind Method; D | 1988 |
25 other studies available for cimetidine and Pruritus
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Aquagenic pruritus.
Topics: Adult; Cimetidine; Hand Dermatoses; Histamine H2 Antagonists; Humans; Male; Pruritus; Treatment Outc | 2008 |
Possible involvement of 5-lipoxygenase metabolite in itch-associated response of mosquito allergy in mice.
Topics: Animals; Arachidonate 5-Lipoxygenase; Betamethasone Valerate; Bridged Bicyclo Compounds, Heterocycli | 2007 |
Dermatographism treated with hydroxyzine and cimetidine and ranitidine.
Topics: Adult; Cimetidine; Dermatitis, Atopic; Drug Therapy, Combination; Humans; Hydroxyzine; Male; Pruritu | 1984 |
Alternative to corticosteroids in the management of pruritus in dogs.
Topics: Animals; Chlorpheniramine; Cimetidine; Dog Diseases; Dogs; Glucocorticoids; Guanidines; Histamine H1 | 1981 |
Effects of cimetidine, ranitidine and promethazine on histamine--induced dermal weals and pruritus--a case study.
Topics: Adult; Cimetidine; Drug Eruptions; Drug Therapy, Combination; Histamine; Humans; Male; Methyltestost | 1983 |
Successful treatment of chronic idiopathic urticaria and angioedema with cimetidine alone.
Topics: Angioedema; Chlorpheniramine; Cimetidine; Double-Blind Method; Drug Therapy, Combination; Histamine; | 1984 |
Therapeutic briefs. I.
Topics: Adult; Anti-Bacterial Agents; Aspirin; Child; Cimetidine; Cyclophosphamide; Dipyridamole; Female; Hu | 1980 |
The use of cimetidine for the treatment of pruritus in polycythemia vera.
Topics: Cimetidine; Guanidines; Humans; Polycythemia Vera; Pruritus | 1982 |
Hypersensitivity to cimetidine.
Topics: Adult; Angioedema; Cimetidine; Drug Hypersensitivity; Female; Guanidines; Humans; Pruritus | 1982 |
Histamine receptors in human skin: indirect evidence.
Topics: Capillary Permeability; Chlorpheniramine; Cimetidine; Humans; Methylhistamines; Mitosis; Pruritus; R | 1982 |
[Pruritus in Hodgkin's disease responding to cimetidine].
Topics: Adult; Cimetidine; Female; Guanidines; Hodgkin Disease; Humans; Lomustine; Prednisone; Procarbazine; | 1981 |
Cimetidine for pruritus in Hodgkin's disease.
Topics: Adult; Cimetidine; Guanidines; Hodgkin Disease; Humans; Male; Pruritus | 1980 |
Cimetidine for pruritus related to systemic disorders.
Topics: Cimetidine; Guanidines; Humans; Pruritus | 1980 |
[Trial treatment of the pruritus in Vaquez' disease with cimetidine].
Topics: Aged; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Polycythemia Vera; Pruritus | 1980 |
[Pruritus induced by cimetidine].
Topics: Aged; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Pruritus | 1981 |
Fixed drug eruption due to cimetidine.
Topics: Cimetidine; Drug Eruptions; Erythema; Female; Hand Dermatoses; Humans; Middle Aged; Pruritus | 1995 |
Cimetidine for pruritus.
Topics: Aged; Anemia, Aplastic; Cimetidine; Female; Guanidines; Humans; Pruritus | 1979 |
Cimetidine doesn't help pruritus of uremia.
Topics: Cimetidine; Guanidines; Humans; Pruritus; Uremia | 1979 |
Cimetidine treatment of pruritus in polycythemia vera.
Topics: Cimetidine; Female; Guanidines; Humans; Middle Aged; Polycythemia Vera; Pruritus | 1978 |
Cimetidine for the treatment of pruritus.
Topics: Cimetidine; Guanidines; Humans; Myeloproliferative Disorders; Pruritus | 1979 |
Pruritus, cimetidine and polycythemia.
Topics: Aged; Cimetidine; Female; Guanidines; Humans; Polycythemia Vera; Pruritus | 1979 |
[Hyperpigmented striae after bleomycin therapy].
Topics: Aged; Bleomycin; Cimetidine; Hodgkin Disease; Humans; Male; Pigmentation Disorders; Pruritus | 1988 |
Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions.
Topics: Acute Disease; Adolescent; Adult; Aged; Anaphylaxis; Child; Cimetidine; Dermatitis, Contact; Drug Ev | 1987 |
[Itching of the skin in myeloproliferative disease treated with cimetidine].
Topics: Aged; Cimetidine; Female; Humans; Male; Middle Aged; Myeloproliferative Disorders; Pruritus | 1985 |