mirtazapine has been researched along with Pruritus in 14 studies
Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.
Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although, compared to baseline, both gabapentin and mirtazapine treatment resulting in significant improvement in VAS scores, decreasing in pruritus severity was significantly greater in the mirtazapine treatment period compared with the gabapentin treatment period (P < 0." | 9.34 | Effect of mirtazapine on pruritus in patients on hemodialysis: a cross-over pilot study. ( Gholyaf, M; Mehrpooya, M; Mirjalili, M; Mohammadi, Y; Sheikh, V; Yasrebifar, F, 2020) |
| "Pruritus was significantly more frequent in the placebo group compared with the mirtazapine group (75% vs 52%, respectively; P=0." | 9.13 | Prophylactic mirtazapine reduces intrathecal morphine-induced pruritus. ( Chang, FL; Ho, ST; Huang, ST; Lee, CH; Sheen, MJ; Tsung, YC, 2008) |
| "Through a thorough literature review of PubMed, we identified all reports of the use of mirtazapine for pruritus." | 9.12 | Defining the role of mirtazapine in the treatment of refractory pruritus. ( Chamseddin, BH; Fawaz, B; Griffin, JR, 2021) |
| "Pruritus is a debilitating symptom that can be associated with cutaneous involvement by an underlying malignancy." | 5.43 | Effective use of mirtazapine for refractory pruritus associated with carcinoma en cuirasse. ( Carlberg, VM; Girouard, SD; Lee, JJ; Mostaghimi, A, 2016) |
| " Although, compared to baseline, both gabapentin and mirtazapine treatment resulting in significant improvement in VAS scores, decreasing in pruritus severity was significantly greater in the mirtazapine treatment period compared with the gabapentin treatment period (P < 0." | 5.34 | Effect of mirtazapine on pruritus in patients on hemodialysis: a cross-over pilot study. ( Gholyaf, M; Mehrpooya, M; Mirjalili, M; Mohammadi, Y; Sheikh, V; Yasrebifar, F, 2020) |
| "Pruritus is a relatively rare but distressing symptom associated with cholestasis, renal failure, and malignancies." | 5.32 | Mirtazapine for pruritus. ( Andresen, S; Davis, MP; Frandsen, JL; Taylor, S; Walsh, D, 2003) |
| "Mirtazapine is a safe medication without serious side effects and may be an effective alternative for the treatment of nocturnal pruritus." | 5.32 | Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: a pilot study. ( Hundley, JL; Yosipovitch, G, 2004) |
| "Pruritus was significantly more frequent in the placebo group compared with the mirtazapine group (75% vs 52%, respectively; P=0." | 5.13 | Prophylactic mirtazapine reduces intrathecal morphine-induced pruritus. ( Chang, FL; Ho, ST; Huang, ST; Lee, CH; Sheen, MJ; Tsung, YC, 2008) |
| "Through a thorough literature review of PubMed, we identified all reports of the use of mirtazapine for pruritus." | 5.12 | Defining the role of mirtazapine in the treatment of refractory pruritus. ( Chamseddin, BH; Fawaz, B; Griffin, JR, 2021) |
| "Psoriasis is a common chronic inflammatory skin disease observed in about 1-3% of the general population." | 2.53 | Itch in Psoriasis Management. ( Reich, A; Szepietowski, JC, 2016) |
| "In cases of malignancy that are refractive to treatment, other therapies have been found to be effective for paraneoplastic itch, including selective serotonin reuptake inhibitors, mirtazapine, gabapentin, thalidomide, opioids, aprepitant, and histone deacetylase inhibitors." | 2.53 | Paraneoplastic Itch Management. ( Rowe, B; Yosipovitch, G, 2016) |
| "Pruritus is a debilitating symptom that can be associated with cutaneous involvement by an underlying malignancy." | 1.43 | Effective use of mirtazapine for refractory pruritus associated with carcinoma en cuirasse. ( Carlberg, VM; Girouard, SD; Lee, JJ; Mostaghimi, A, 2016) |
| "Pruritus is a relatively rare but distressing symptom associated with cholestasis, renal failure, and malignancies." | 1.32 | Mirtazapine for pruritus. ( Andresen, S; Davis, MP; Frandsen, JL; Taylor, S; Walsh, D, 2003) |
| "Mirtazapine is a safe medication without serious side effects and may be an effective alternative for the treatment of nocturnal pruritus." | 1.32 | Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: a pilot study. ( Hundley, JL; Yosipovitch, G, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Bromberg, H | 1 |
| Chang, Y | 1 |
| Craig, D | 1 |
| Gholyaf, M | 1 |
| Sheikh, V | 1 |
| Yasrebifar, F | 1 |
| Mohammadi, Y | 1 |
| Mirjalili, M | 1 |
| Mehrpooya, M | 1 |
| Ferreira, S | 1 |
| Azevedo, A | 1 |
| Velho, GC | 1 |
| Sanches, M | 1 |
| Selores, M | 1 |
| Lee, HG | 1 |
| Grossman, SK | 1 |
| Valdes-Rodriguez, R | 1 |
| Berenato, F | 1 |
| Korbutov, J | 1 |
| Chan, YH | 1 |
| Lavery, MJ | 1 |
| Yosipovitch, G | 5 |
| Fawaz, B | 1 |
| Chamseddin, BH | 1 |
| Griffin, JR | 1 |
| Bernhard, JD | 1 |
| Lee, JJ | 1 |
| Girouard, SD | 1 |
| Carlberg, VM | 1 |
| Mostaghimi, A | 1 |
| Szepietowski, JC | 1 |
| Reich, A | 1 |
| Rowe, B | 1 |
| Sheen, MJ | 1 |
| Ho, ST | 1 |
| Lee, CH | 1 |
| Tsung, YC | 1 |
| Chang, FL | 1 |
| Huang, ST | 1 |
| Davis, MP | 1 |
| Frandsen, JL | 1 |
| Walsh, D | 1 |
| Andresen, S | 1 |
| Taylor, S | 1 |
| Hundley, JL | 1 |
| Dawn, A | 1 |
| Demierre, MF | 1 |
| Taverna, J | 1 |
5 reviews available for mirtazapine and Pruritus
| Article | Year |
|---|---|
Defining the role of mirtazapine in the treatment of refractory pruritus.
Topics: Analgesics, Opioid; Antidepressive Agents; Clinical Trials as Topic; Humans; Mirtazapine; Pruritus; | 2021 |
Clinical practice. Chronic pruritus.
Topics: Amines; Antidepressive Agents, Tricyclic; Behavior Therapy; Chronic Disease; Cyclohexanecarboxylic A | 2013 |
Itch in Psoriasis Management.
Topics: Adaptation, Psychological; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Doxepin; | 2016 |
Paraneoplastic Itch Management.
Topics: Acantholysis; Acanthosis Nigricans; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Apre | 2016 |
Treating itch in psoriasis.
Topics: Administration, Cutaneous; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipr | 2006 |
2 trials available for mirtazapine and Pruritus
| Article | Year |
|---|---|
Effect of mirtazapine on pruritus in patients on hemodialysis: a cross-over pilot study.
Topics: Adult; Aged; Aged, 80 and over; Cross-Over Studies; Female; Histamine H1 Antagonists; Humans; Male; | 2020 |
Prophylactic mirtazapine reduces intrathecal morphine-induced pruritus.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Double-Blind Method; Female; Histamine H1 Antagonists | 2008 |
7 other studies available for mirtazapine and Pruritus
| Article | Year |
|---|---|
Pruritic Manifestation of Peripheral T Cell Lymphoma Effectively Managed with Mirtazapine: A Case Report.
Topics: Aged; Antidepressive Agents, Tricyclic; Humans; Lymphoma, T-Cell, Peripheral; Male; Mirtazapine; Pru | 2020 |
Epidermolysis Bullosa Pruriginosa successfully treated with concomitant topical and systemic agents.
Topics: Administration, Topical; Amitriptyline; Analgesics; Drug Therapy, Combination; Epidermolysis Bullosa | 2020 |
Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability.
Topics: Aged; Amines; Amitriptyline; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy, | 2017 |
Effective use of mirtazapine for refractory pruritus associated with carcinoma en cuirasse.
Topics: Aged; Antidepressive Agents, Tricyclic; Antipruritics; Carcinoma, Ductal, Breast; Female; Histamine | 2016 |
Mirtazapine for pruritus.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Cholestasis; Female; Histamine H1 Antagon | 2003 |
Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: a pilot study.
Topics: Adolescent; Adrenergic alpha-Antagonists; Antidepressive Agents, Tricyclic; Female; Humans; Mianseri | 2004 |
Mirtazapine and gabapentin for reducing pruritus in cutaneous T-cell lymphoma.
Topics: Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Gabapentin; | 2006 |