| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Innate Inflammatory Response
[description not available] | 0 | 2.05 | 1 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 1 | 4.05 | 1 | 0 |
Encephalitis, Polio
[description not available] | 0 | 2.06 | 1 | 0 |
Poliomyelitis
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5) | 0 | 2.06 | 1 | 0 |
Acute Liver Injury, Drug-Induced
[description not available] | 0 | 2.06 | 1 | 0 |
Adverse Drug Event
[description not available] | 0 | 2.06 | 1 | 0 |
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 2.06 | 1 | 0 |
Drug-Related Side Effects and Adverse Reactions
Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals. | 0 | 2.06 | 1 | 0 |
Anemia, Fanconi
[description not available] | 0 | 2.13 | 1 | 0 |
Fanconi Anemia
Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004) | 0 | 2.13 | 1 | 0 |
Lichen Ruber Planus
[description not available] | 0 | 2.41 | 1 | 0 |
Lichen Planus
An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a saw-tooth pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown. | 0 | 2.41 | 1 | 0 |
Skin Aging
The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight. | 0 | 3.81 | 2 | 1 |
Disease Exacerbation
[description not available] | 0 | 2.77 | 3 | 0 |
Licheniform Eruptions
[description not available] | 0 | 3.82 | 2 | 1 |
Cafe-au-Lait Spots
Light brown pigmented macules associated with NEUROFIBROMATOSIS and Albright's syndrome (see FIBROUS DYSPLASIA, POLYOSTOTIC). | 0 | 2.15 | 1 | 0 |
Nevus Flammeus
[description not available] | 0 | 2.15 | 1 | 0 |
Petechiae
Pinhead size (3 mm) skin discolorization due to hemorrhage. | 0 | 2.46 | 2 | 0 |
Incontinentia Pigmenti Achromians
[description not available] | 0 | 2.46 | 2 | 0 |
Mycosis Fungoides
A chronic, malignant T-cell lymphoma of the skin. In the late stages, the LYMPH NODES and viscera are affected. | 0 | 2.15 | 1 | 0 |
Purpura
Purplish or brownish red discoloration, easily visible through the epidermis, caused by hemorrhage into the tissues. When the size of the discolorization is | 0 | 2.46 | 2 | 0 |
Port-Wine Stain
A vascular malformation of developmental origin characterized pathologically by ectasia of superficial dermal capillaries, and clinically by persistent macular erythema. In the past, port wine stains have frequently been termed capillary hemangiomas, which they are not; unfortunately this confusing practice persists: HEMANGIOMA, CAPILLARY is neoplastic, a port-wine stain is non-neoplastic. Port-wine stains vary in color from fairly pale pink to deep red or purple and in size from a few millimeters to many centimeters in diameter. The face is the most frequently affected site and they are most often unilateral. (From Rook et al., Textbook of Dermatology, 5th ed, p483) | 0 | 2.15 | 1 | 0 |
Allergic Contact Dermatitis
[description not available] | 0 | 4.32 | 7 | 0 |
Dermatitis, Allergic Contact
A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure. | 0 | 4.32 | 7 | 0 |
Exanthem
[description not available] | 0 | 2.08 | 1 | 0 |
Cancer of Gastrointestinal Tract
[description not available] | 0 | 2.08 | 1 | 0 |
Exanthema
Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology. | 0 | 2.08 | 1 | 0 |
Chronic Illness
[description not available] | 0 | 2.11 | 1 | 0 |
Hand Dermatosis
[description not available] | 0 | 2.49 | 2 | 0 |
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 2.11 | 1 | 0 |
Hand Dermatoses
Skin diseases involving the HANDS. | 0 | 2.49 | 2 | 0 |
Palmoplantaris Pustulosis
[description not available] | 0 | 6.37 | 9 | 1 |
Psoriasis
A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis. | 1 | 8.37 | 9 | 1 |
Recrudescence
[description not available] | 0 | 2.71 | 3 | 0 |
Bleb
[description not available] | 0 | 3.82 | 2 | 1 |
Dermatosclerosis
[description not available] | 0 | 2.15 | 1 | 0 |
Scleroderma, Localized
A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules. | 0 | 2.15 | 1 | 0 |
Anesthesia
A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures. | 0 | 3.43 | 1 | 1 |
Acantholysis
Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE. | 0 | 2.05 | 1 | 0 |
Complications, Pregnancy
[description not available] | 0 | 2.05 | 1 | 0 |
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 2.05 | 1 | 0 |
Eczema, Atopic
[description not available] | 0 | 8.64 | 19 | 10 |
Dermatomycoses
Superficial infections of the skin or its appendages by any of various fungi. | 0 | 2.06 | 1 | 0 |
Dermatitis, Atopic
A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema. | 1 | 10.64 | 19 | 10 |
Sycosis
[description not available] | 0 | 2.01 | 1 | 0 |
Bullous Dermatoses
[description not available] | 0 | 2.01 | 1 | 0 |
Folliculitis
Inflammation of follicles, primarily hair follicles. | 0 | 2.01 | 1 | 0 |
Contact Dermatitis
[description not available] | 0 | 4.87 | 8 | 1 |
Lichen Simplex Chronicus
[description not available] | 0 | 2.4 | 2 | 0 |
Dermatitis, Contact
A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms. | 0 | 4.87 | 8 | 1 |
Neurodermatitis
An extremely variable eczematous skin disease that is presumed to be a response to prolonged vigorous scratching, rubbing, or pinching to relieve intense pruritus. It varies in intensity, severity, course, and morphologic expression in different individuals. Neurodermatitis is believed by some to be psychogenic. The circumscribed or localized form is often referred to as lichen simplex chronicus. | 0 | 2.4 | 2 | 0 |
Dermatoses
[description not available] | 0 | 4.71 | 2 | 1 |
Atrophy
Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes. | 0 | 8.1 | 11 | 6 |
Skin Diseases
Diseases involving the DERMIS or EPIDERMIS. | 1 | 6.71 | 2 | 1 |
Lichen Nitidus
A chronic inflammatory disease characterized by shiny, flat-topped, usually flesh-colored micropapules no larger than the head of a pin. Lesions are localized in the early stages, found chiefly on the lower abdomen, penis, and inner surface of the thighs. Distribution may become generalized as the disease progresses. | 0 | 2.02 | 1 | 0 |
Leg Dermatoses
A nonspecific term used to denote any cutaneous lesion or group of lesions, or eruptions of any type on the leg. (From Stedman, 25th ed) | 0 | 2.02 | 1 | 0 |
Microbial Superinvasion
[description not available] | 0 | 2.02 | 1 | 0 |
Molluscum Contagiosum
A common, benign, usually self-limited viral infection of the skin and occasionally the conjunctivae by a poxvirus (MOLLUSCUM CONTAGIOSUM VIRUS). (Dorland, 27th ed) | 0 | 2.02 | 1 | 0 |
Itching
[description not available] | 0 | 4.36 | 2 | 2 |
Infections, Staphylococcal Skin
[description not available] | 0 | 4.35 | 2 | 2 |
Pruritus
An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief. | 0 | 4.36 | 2 | 2 |
Staphylococcal Skin Infections
Infections to the skin caused by bacteria of the genus STAPHYLOCOCCUS. | 0 | 4.35 | 2 | 2 |
Facial Dermatoses
Skin diseases involving the FACE. | 0 | 2.4 | 2 | 0 |
Lupus Erythematosus, Cutaneous, Subacute
[description not available] | 0 | 2.03 | 1 | 0 |
Lupus Erythematosus, Cutaneous
A form of lupus erythematosus in which the skin may be the only organ involved or in which skin involvement precedes the spread into other body systems. It has been classified into three forms - acute (= LUPUS ERYTHEMATOSUS, SYSTEMIC with skin lesions), subacute, and chronic (= LUPUS ERYTHEMATOSUS, DISCOID). | 0 | 2.03 | 1 | 0 |
Nail Diseases
Diseases of the nail plate and tissues surrounding it. The concept is limited to primates. | 0 | 2.03 | 1 | 0 |
Disseminated Superficial Actinic Porokeratosis
[description not available] | 0 | 2.03 | 1 | 0 |
Porokeratosis
A heritable disorder of faulty keratinization characterized by the proliferation of abnormal clones of KERATINOCYTES and lesions showing varying atrophic patches surrounded by an elevated, keratotic border. These keratotic lesions can progress to overt cutaneous neoplasm. Several clinical variants are recognized, including porokeratosis of Mibelli, linear porokeratosis, disseminated superficial actinic porokeratosis, palmoplantar porokeratosis, and punctate porokeratosis. | 0 | 2.03 | 1 | 0 |
Erythema
Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes. | 0 | 5.21 | 4 | 3 |
Dermatitis Medicamentosa
[description not available] | 0 | 5.94 | 5 | 2 |
Spider Veins
[description not available] | 0 | 5.53 | 3 | 2 |
Telangiectasis
Permanent dilation of preexisting blood vessels (CAPILLARIES; ARTERIOLES; VENULES) creating small focal red lesions, most commonly in the skin or mucous membranes. It is characterized by the prominence of skin blood vessels, such as vascular spiders. | 0 | 5.53 | 3 | 2 |
Eczematous Disorders
[description not available] | 0 | 3.37 | 1 | 1 |
Dermatitis, Contact, Phototoxic
[description not available] | 0 | 3.37 | 1 | 1 |
Keratoderma Blennorrhagicum
[description not available] | 0 | 3.37 | 1 | 1 |
Keratosis
Any horny growth such as a wart or callus. | 0 | 3.37 | 1 | 1 |
Albinism
General term for a number of inherited defects of amino acid metabolism in which there is a deficiency or absence of pigment in the eyes, skin, or hair. | 0 | 1.99 | 1 | 0 |
Vitiligo
A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached. | 0 | 1.99 | 1 | 0 |
Anasarca
[description not available] | 0 | 1.99 | 1 | 0 |
Edema
Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE. | 0 | 1.99 | 1 | 0 |
Dermatitis
Any inflammation of the skin. | 0 | 5.71 | 11 | 2 |
Eosinophilia, Tropical
[description not available] | 0 | 2 | 1 | 0 |
Pemphigoid
[description not available] | 0 | 2 | 1 | 0 |
Mange, Sarcoptic
[description not available] | 0 | 2 | 1 | 0 |
Eosinophilia
Abnormal increase of EOSINOPHILS in the blood, tissues or organs. | 0 | 2 | 1 | 0 |
Pemphigoid, Bullous
A chronic and relatively benign subepidermal blistering disease usually of the elderly and without histopathologic acantholysis. | 0 | 2 | 1 | 0 |
Scabies
A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body. | 0 | 2 | 1 | 0 |
Acute Disease
Disease having a short and relatively severe course. | 0 | 4.34 | 2 | 2 |
Dermatitis, Eczematous
[description not available] | 0 | 5.52 | 6 | 3 |
Eczema
A pruritic papulovesicular dermatitis occurring as a reaction to many endogenous and exogenous agents (Dorland, 27th ed). | 1 | 7.52 | 6 | 3 |
Leg Ulcer
Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes. | 0 | 1.97 | 1 | 0 |
Dermatitis Seborrheica
[description not available] | 0 | 3.76 | 2 | 1 |
Dermatitis, Seborrheic
A chronic inflammatory disease of the skin with unknown etiology. It is characterized by moderate ERYTHEMA, dry, moist, or greasy (SEBACEOUS GLAND) scaling and yellow crusted patches on various areas, especially the scalp, that exfoliate as dandruff. Seborrheic dermatitis is common in children and adolescents with HIV INFECTIONS. | 0 | 3.76 | 2 | 1 |
Bacterial Disease
[description not available] | 0 | 3.35 | 1 | 1 |
Impetigo Contagiosa
[description not available] | 0 | 3.35 | 1 | 1 |
Bacterial Infections
Infections by bacteria, general or unspecified. | 0 | 3.35 | 1 | 1 |
Impetigo
A common superficial bacterial infection caused by STAPHYLOCOCCUS AUREUS or group A beta-hemolytic streptococci. Characteristics include pustular lesions that rupture and discharge a thin, amber-colored fluid that dries and forms a crust. This condition is commonly located on the face, especially about the mouth and nose. | 0 | 3.35 | 1 | 1 |
Sunburn
An injury to the skin causing erythema, tenderness, and sometimes blistering and resulting from excessive exposure to the sun. The reaction is produced by the ultraviolet radiation in sunlight. | 0 | 1.96 | 1 | 0 |
Granulomas
[description not available] | 0 | 1.96 | 1 | 0 |
Granuloma
A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents. | 0 | 1.96 | 1 | 0 |
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 1.96 | 1 | 0 |