Page last updated: 2024-08-21

chenodeoxycholic acid and Pruritus

chenodeoxycholic acid has been researched along with Pruritus in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199013 (40.63)18.7374
1990's1 (3.13)18.2507
2000's1 (3.13)29.6817
2010's11 (34.38)24.3611
2020's6 (18.75)2.80

Authors

AuthorsStudies
Carino, A; Cipriani, S; D'Amore, C; De Marino, S; Festa, C; Finamore, C; Fiorucci, S; Monti, MC; Renga, B; Sepe, V; Zampella, A1
Chan, KE; Chee, D; Chew, NWS; Fu, CE; Huang, DQ; Muthiah, M; Nah, B; Ng, CH; Noureddin, M; Sanyal, AJ; Siddqui, MS; Tan, C; Tan, DJH; Tang, ASP; Teng, M; Wong, GHZ; Wong, ZY; Xiao, J; Yong, JN; Zeng, RW1
Andreone, P; Bowlus, CL; Floreani, A; Goldberg, D; Hirschfield, GM; Jin, Y; Kowdley, KV; LaRusso, NF; Levy, C; MacConell, L; Pencek, R; Rushbrook, S; Schiano, T; Shapiro, D; Shrestha, R; Trotter, J; Vuppalanchi, R1
de Veer, RC; Laschtowitz, A; Schramm, C; Van der Meer, AJ1
Korf, H; Nevens, F; Smets, L; van der Merwe, S; Verbeek, J1
Gershwin, ME; Hirschfield, GM; Lleo, A; Wang, GQ1
Anstee, QM; Barritt, AS; Bonacci, M; Cawkwell, G; Harrison, S; Loomba, R; Nader, F; Noureddin, M; Ratziu, V; Rinella, M; Sanyal, AJ; Schattenberg, JM; Stepanova, M; Wong, B; Younossi, ZM1
Bergasa, NV1
Hirschfield, GM; Webb, GJ1
Corrigan, M; Hegade, VS; Hirschfield, GM; Holmes, E; Jones, DE; Kendrick, S; Marchesi, JR; McDonald, JAK; Pechlivanis, A; Rees, D; Taylor-Robinson, SD1
Kowdley, KV; Manne, V1
Eaton, JE; Gores, GJ1
Andreone, P; Bowlus, CL; Drenth, JPH; Hirschfield, GM; MacConell, L; Malecha, ES; Nevens, F; Pencek, R; Shapiro, D; Shiffman, ML; Trauner, M; Vargas, V1
Adorini, L; Beecher-Jones, T; Bodhenheimer, HC; Böhm, O; Castelloe, E; Gordon, SC; Hirschfield, GM; Kowdley, KV; Lindor, K; Luketic, V; Marschall, HU; Mason, A; Mayo, M; Parés, A; Sciacca, C; Shapiro, D; Trauner, M; Vincent, C1
Gershwin, ME; Hirschfield, GM; Trivedi, PJ1
Andreone, P; Beuers, U; Bowlus, C; Drenth, JP; Floreani, A; Hansen, B; Hirschfield, GM; Hohenester, S; Hooshmand-Rad, R; Invernizzi, P; Jones, DE; Kowdley, KV; Lindor, KD; Luketic, V; MacConell, L; Marmon, T; Marschall, HU; Mazzella, G; Nevens, F; Pencek, R; Pockros, PJ; Pruzanski, M; Regula, J; Shah, H; Shapiro, D; Sheeron, S; Shiffman, M; Strasser, SI; Trauner, M; van Erpecum, KJ; Vargas, V; Vincent, C1
Jankowska, I; Socha, P1
Heikkinen, J; Jänne, O; Mäentausta, O; Ylöstalo, P2
Anna, M; Antonio, C; Azzaroli, F; Bovicelli, L; Colecchia, A; Constance, M; Davide, F; Enrico, R; Festi, D; Francesco, A; Giovanni, N; Giuliana, S; Luciano, B; Mazzella, G; Miracolo, A; Mwangemi, C; Nicola, R; Nigro, G; Patrizia, S; Rizzo, N; Roda, E; Simonazzi, G; Simoni, P1
Laatikainen, TJ1
Laatikainen, T1
Ikonen, E; Laatikainen, T1
Bloomer, JR; Ghent, CN; Klatskin, G1
Hanson, RF; Isenberg, JN; Page, AR; Sharp, HL; Williams, GC; Zavoral, J1
Bloomer, JR; Boyer, JL1
Clayton, P; Gunasekaran, T; Ichimiya, H; Nazer, H; Sjövall, J1
Burton, JL; Heaton, KW; Kirby, J1
Fehér, T; Kazik, MH; Papp, J1
Admirand, WH; Stiehl, A; Thaler, MM1
Russell, RI1
Chen, T; Leevy, CM; Zaki, FG1

Reviews

7 review(s) available for chenodeoxycholic acid and Pruritus

ArticleYear
Safety and tolerability of obeticholic acid in chronic liver disease: a pooled analysis of 1878 individuals.
    Hepatology communications, 2023, 03-01, Volume: 7, Issue:3

    Topics: Chenodeoxycholic Acid; Humans; Longitudinal Studies; Non-alcoholic Fatty Liver Disease; Pruritus

2023
Diagnosis and treatment of primary biliary cholangitis.
    United European gastroenterology journal, 2020, Volume: 8, Issue:6

    Topics: Autoantigens; Autoimmune Diseases; Bezafibrate; Biomarkers; Biopsy; Chenodeoxycholic Acid; Cholagogues and Choleretics; Disease Progression; Drug Therapy, Combination; Elasticity Imaging Techniques; End Stage Liver Disease; Fatigue; Female; Humans; Immunoglobulin M; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Liver Transplantation; Middle Aged; Off-Label Use; Prognosis; Pruritus; Quality of Life; Severity of Illness Index; Sjogren's Syndrome; Survival Rate; Treatment Outcome; Ursodeoxycholic Acid

2020
Primary biliary cholangitis.
    Lancet (London, England), 2020, 12-12, Volume: 396, Issue:10266

    Topics: Autoimmune Diseases; Biomarkers; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Fatigue; Humans; Pruritus; Risk Factors; Ursodeoxycholic Acid

2020
Work in Progress: Drugs in Development.
    Clinics in liver disease, 2018, Volume: 22, Issue:3

    Topics: Abatacept; Acetates; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Bezafibrate; CD40 Antigens; CD40 Ligand; Chalcones; Chemokine CX3CL1; Chenodeoxycholic Acid; Cholic Acids; Drug Development; Fenofibrate; Fibroblast Growth Factors; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Janus Kinase Inhibitors; Liver Cirrhosis, Biliary; Methylamines; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR delta; PPAR gamma; Propionates; Pruritus; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Thiazepines; Triazoles; Ustekinumab

2018
Obeticholic acid in primary biliary cholangitis: where we stand.
    Current opinion in gastroenterology, 2019, Volume: 35, Issue:3

    Topics: Chenodeoxycholic Acid; Cholesterol, HDL; Dose-Response Relationship, Drug; Drug Labeling; Dyslipidemias; Humans; Liver Cirrhosis, Biliary; Nasopharyngitis; Pruritus; Receptors, Cytoplasmic and Nuclear; Treatment Outcome

2019
Obeticholic acid for the treatment of primary biliary cirrhosis.
    Expert review of clinical pharmacology, 2016, Volume: 9, Issue:1

    Topics: Animals; Chenodeoxycholic Acid; Dose-Response Relationship, Drug; End Stage Liver Disease; Humans; Liver Cirrhosis, Biliary; Pruritus; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2016
Differential diagnosis of cholestasis.
    Advances in internal medicine, 1971, Volume: 17

    Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts; Bile Ducts, Intrahepatic; Bilirubin; Cell Division; Chenodeoxycholic Acid; Cholangiography; Cholestasis; Cholic Acids; Coloring Agents; Diagnosis, Differential; Humans; Liver; Liver Function Tests; Mitochondria, Liver; Pruritus; Vitamin K

1971

Trials

6 trial(s) available for chenodeoxycholic acid and Pruritus

ArticleYear
A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis.
    Journal of hepatology, 2020, Volume: 73, Issue:1

    Topics: Alkaline Phosphatase; Chenodeoxycholic Acid; Cholagogues and Choleretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Female; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Pruritus; Treatment Outcome

2020
Obeticholic Acid Impact on Quality of Life in Patients With Nonalcoholic Steatohepatitis: REGENERATE 18-Month Interim Analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2022, Volume: 20, Issue:9

    Topics: Adult; Aged; Chenodeoxycholic Acid; Double-Blind Method; Female; Fibrosis; Humans; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Pruritus; Quality of Life

2022
Long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis: 3-year results of an international open-label extension study.
    The lancet. Gastroenterology & hepatology, 2019, Volume: 4, Issue:6

    Topics: Alkaline Phosphatase; Bilirubin; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Dose-Response Relationship, Drug; Double-Blind Method; Fatigue; Female; Gastrointestinal Agents; Humans; Male; Middle Aged; Pruritus; Ursodeoxycholic Acid

2019
Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid.
    Gastroenterology, 2015, Volume: 148, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Chenodeoxycholic Acid; Cholagogues and Choleretics; Dose-Response Relationship, Drug; Double-Blind Method; Female; gamma-Glutamyltransferase; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Pruritus; Treatment Failure; Treatment Outcome; Ursodeoxycholic Acid

2015
A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.
    The New England journal of medicine, 2016, Aug-18, Volume: 375, Issue:7

    Topics: Adult; Aged; Alkaline Phosphatase; Bile Acids and Salts; Bone Density; Chenodeoxycholic Acid; Double-Blind Method; Female; Fibroblast Growth Factors; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male; Middle Aged; Pruritus

2016
Ursodeoxycholic acid administration in patients with cholestasis of pregnancy: effects on primary bile acids in babies and mothers.
    Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:3

    Topics: Adult; Amniotic Fluid; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Cholic Acid; Dose-Response Relationship, Drug; Female; Fetal Blood; Humans; Infant, Newborn; Male; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pruritus; Ursodeoxycholic Acid

2001

Other Studies

19 other study(ies) available for chenodeoxycholic acid and Pruritus

ArticleYear
Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.
    Journal of medicinal chemistry, 2014, Oct-23, Volume: 57, Issue:20

    Topics: Animals; Bile Acids and Salts; Chemistry Techniques, Synthetic; Cholanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; HEK293 Cells; Hep G2 Cells; Humans; Ligands; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Molecular Targeted Therapy; Pruritus; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Small Molecule Libraries; Structure-Activity Relationship

2014
Improved Markers of Cholestatic Liver Injury in Patients With Primary Biliary Cholangitis Treated With Obeticholic Acid and Bezafibrate.
    Hepatology (Baltimore, Md.), 2021, Volume: 73, Issue:6

    Topics: Alkaline Phosphatase; Bezafibrate; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholesterol; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Female; Humans; Hypolipidemic Agents; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Pruritus; Treatment Outcome

2021
The pruritus of cholestasis: From bile acids to opiate agonists: Relevant after all these years.
    Medical hypotheses, 2018, Volume: 110

    Topics: Animals; Anticholesteremic Agents; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Humans; Lysophospholipids; Models, Biological; Opioid Peptides; Pruritus; Receptors, G-Protein-Coupled; Receptors, Opioid

2018
Autotaxin, bile acid profile and effect of ileal bile acid transporter inhibition in primary biliary cholangitis patients with pruritus.
    Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:5

    Topics: Adult; Aged; Bile Acids and Salts; Biomarkers; Carrier Proteins; Case-Control Studies; Chenodeoxycholic Acid; Cholic Acid; Chromatography, Liquid; Feces; Female; Humans; Liver Cirrhosis, Biliary; Male; Membrane Glycoproteins; Methylamines; Middle Aged; Phosphoric Diester Hydrolases; Pruritus; RNA, Ribosomal, 16S; Tandem Mass Spectrometry; Thiazepines

2019
Long-term outcomes with obeticholic acid in primary biliary cholangitis: reassuring, but still an itch we need to scratch.
    The lancet. Gastroenterology & hepatology, 2019, Volume: 4, Issue:6

    Topics: Chenodeoxycholic Acid; Humans; Liver Cirrhosis, Biliary; Pruritus; Ursodeoxycholic Acid

2019
Progressive familial intrahepatic cholestasis and inborn errors of bile acid synthesis.
    Clinics and research in hepatology and gastroenterology, 2012, Volume: 36, Issue:3

    Topics: Avitaminosis; Bile Acids and Salts; Chenodeoxycholic Acid; Child; Cholestasis, Intrahepatic; Cholic Acid; Digestive System Surgical Procedures; gamma-Glutamyltransferase; Gastrointestinal Agents; Growth Disorders; Hepatomegaly; Humans; Jaundice; Metabolism, Inborn Errors; Pruritus; Splenomegaly; Transaminases

2012
Serum bile acid levels in intrahepatic cholestasis of pregnancy during treatment with phenobarbital or cholestyramine.
    European journal of obstetrics, gynecology, and reproductive biology, 1982, Volume: 14, Issue:3

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis, Intrahepatic; Cholestyramine Resin; Cholic Acids; Deoxycholic Acid; Female; Humans; Liver Function Tests; Phenobarbital; Pregnancy; Pregnancy Complications; Pruritus

1982
Changes in serum bile acid concentrations during normal pregnancy, in patients with intrahepatic cholestasis of pregnancy and in pregnant women with itching.
    British journal of obstetrics and gynaecology, 1981, Volume: 88, Issue:3

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis, Intrahepatic; Cholic Acids; Deoxycholic Acid; Female; Humans; Postpartum Period; Pregnancy; Pregnancy Complications; Pruritus

1981
Fetal bile acid levels in pregnancies complicated by maternal intrahepatic cholestasis.
    American journal of obstetrics and gynecology, 1975, Aug-01, Volume: 122, Issue:7

    Topics: Androstenols; Apgar Score; Birth Weight; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Chromatography, Gas; Dehydroepiandrosterone; Female; Fetal Blood; Fetal Distress; Humans; Infant, Newborn; Labor, Induced; Pregnancy; Pregnancy Complications; Pregnanediol; Pruritus; Transaminases

1975
Effect of cholestyramine and phenobarbital on pruritus and serum bile acid levels in cholestasis of pregnancy.
    American journal of obstetrics and gynecology, 1978, Nov-01, Volume: 132, Issue:5

    Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholestyramine Resin; Cholic Acids; Female; Humans; Phenobarbital; Pregnancy; Pregnancy Complications; Pruritus

1978
Serum bile acids in cholestasis of pregnancy.
    Obstetrics and gynecology, 1977, Volume: 50, Issue:3

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Female; Fetal Distress; Humans; Infant, Newborn; Liver Function Tests; Placenta; Pregnancy; Pregnancy Complications; Pruritus

1977
Elevations in skin tissue levels of bile acids in human cholestasis: relation to serum levels and topruritus.
    Gastroenterology, 1977, Volume: 73, Issue:5

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Female; Humans; Lithocholic Acid; Male; Middle Aged; Pruritus; Skin

1977
Immunodeficiency, xanthomas and obstructive liver disease.
    The American journal of medicine, 1976, Volume: 61, Issue:3

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Child; Cholestyramine Resin; Cholic Acids; Humans; Hypercholesterolemia; Hyperlipidemias; Immunologic Deficiency Syndromes; Liver Diseases; Male; Phenobarbital; Pruritus; Xanthomatosis

1976
Phenobarbital effects in cholestatic liver diseases.
    Annals of internal medicine, 1975, Volume: 82, Issue:3

    Topics: Adult; Bile Ducts, Intrahepatic; Bilirubin; Chenodeoxycholic Acid; Child; Child, Preschool; Cholangitis; Cholestasis; Cholic Acids; Feces; Female; Hepatitis; Humans; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Phenobarbital; Pruritus; Rose Bengal; Sulfobromophthalein

1975
Treatment of chronic liver disease caused by 3 beta-hydroxy-delta 5-C27-steroid dehydrogenase deficiency with chenodeoxycholic acid.
    Archives of disease in childhood, 1990, Volume: 65, Issue:10

    Topics: 3-Hydroxysteroid Dehydrogenases; Administration, Oral; Chenodeoxycholic Acid; Child, Preschool; Chronic Disease; Growth Disorders; Humans; Liver Diseases; Male; Pruritus

1990
Pruritic effect of bile salts.
    British medical journal, 1974, Dec-21, Volume: 4, Issue:5946

    Topics: Adolescent; Adult; Aged; Bile Acids and Salts; Blister; Chenodeoxycholic Acid; Cholestasis; Cholic Acids; Deoxycholic Acid; Female; Humans; Male; Middle Aged; Pruritus; Skin Tests

1974
Spectrofluorimetric determination of individual bile acids in biological fluids: peripheral plasma.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Mar-30, Volume: 44, Issue:3

    Topics: Acetylation; Adolescent; Adult; Aged; Animals; Bile Acids and Salts; Carbon Isotopes; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Thin Layer; Deoxycholic Acid; Dogs; Female; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male; Methylation; Middle Aged; Pruritus; Spectrometry, Fluorescence

1973
Effects of phenobarbital on bile salt metabolism in cholestasis due to intrahepatic bile duct hypoplasia.
    Pediatrics, 1973, Volume: 51, Issue:6

    Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts, Intrahepatic; Bilirubin; Carbon Isotopes; Chenodeoxycholic Acid; Child, Preschool; Cholestasis; Cholic Acids; Feces; Female; Half-Life; Humans; Leucyl Aminopeptidase; Liver; Phenobarbital; Pruritus

1973
Clinical aspects of alterations in bile acid metabolism--the wrong bile acids in the wrong place.
    Scottish medical journal, 1973, Volume: 18, Issue:5

    Topics: Bile Acids and Salts; Biliary Tract Diseases; Celiac Disease; Chenodeoxycholic Acid; Cholestasis; Colonic Diseases; Diarrhea; Hepatitis A; Ileum; Intestinal Mucosa; Intestine, Small; Lithocholic Acid; Liver Cirrhosis; Malabsorption Syndromes; Neomycin; Pancreatitis; Pruritus; Zollinger-Ellison Syndrome

1973