clomipramine has been researched along with Pruritus in 4 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To develop a behavioral model in mice that is capable of mimicking some distinctive symptoms of human posttraumatic trigeminal neuropathic pain such as spontaneous pain, cold allodynia, and chemical÷inflammatory hyperalgesia, and to use this model to investigate the antinociceptive effects of clomipramine and tramadol, two drugs used for the treatment of neuropathic pain." | 3.77 | Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice. ( Alvarez, P; Brun, A; Constandil, L; Correa, A; Hernández, A; Labertrandie, A; Lopez, J; Pelissier, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Alvarez, P | 1 |
| Brun, A | 1 |
| Labertrandie, A | 1 |
| Lopez, J | 1 |
| Correa, A | 1 |
| Constandil, L | 1 |
| Hernández, A | 1 |
| Pelissier, T | 1 |
| Nishimura, Y | 1 |
| Kitoh, A | 1 |
| Yoshida, Y | 1 |
| Tanaka, T | 1 |
| Black, DW | 1 |
| Blum, N | 1 |
4 other studies available for clomipramine and Pruritus
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Antihyperalgesic effects of clomipramine and tramadol in a model of posttraumatic trigeminal neuropathic pain in mice.
Topics: Acetone; Analgesics, Opioid; Animals; Capsaicin; Clomipramine; Disease Models, Animal; Formaldehyde; | 2011 |
Clomipramine-induced hypersensitivity syndrome with unusual clinical features.
Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Cytokines; Drug Hypersensitivity; Female; Her | 2005 |
Trichotillomania treated with clomipramine and a topical steroid.
Topics: Administration, Topical; Adult; Clomipramine; Female; Fluocinolone Acetonide; Humans; Pruritus; Tric | 1992 |