homocysteine and Osteoporosis

homocysteine has been researched along with Osteoporosis in 75 studies

Research

Studies (75)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (1.33)	18.2507
2000's	42 (56.00)	29.6817
2010's	29 (38.67)	24.3611
2020's	3 (4.00)	2.80

Authors

Authors	Studies
Ilesanmi-Oyelere, BL; Kruger, MC	1
Qiu, B; Wang, C; Zhang, X	1
Azzini, E; Polito, A; Ruggeri, S	1
Asukai, M; Fujita, T; Matsuyama, Y; Nishida, T; Ohishi, T; Suzuki, D	1
Álvarez-Ríos, AI; Álvarez-Sánchez, N; Carrillo-Vico, A; Cruz-Chamorro, I; García-García, FJ; Guerrero, JM; Lardone, PJ; Rodríguez-Mañas, L	1
Marumo, K; Saito, M	2
Das, RS; Das, TK; Desai, M; Khatkhatay, MI; Pasi, A; Sachdeva, G; Saoji, R	1
Kalani, A; Tyagi, N; Tyagi, SC; Vacek, TP; Voor, MJ	1
Gupta, S; Khandelwal, M; Manglani, K; Singh, RR; Surolia, A; Vijayan, V	1
Chung, WY; Hwang, SC; Jung, YJ; Ki, SK; Kim, BT; Kim, K; Lee, KS; Lee, M; Oh, YM; Park, JH; Park, KJ; Park, SB; Sheen, S; Sun, JS	1
Clarke, M; Dickey, W; Hoey, L; McNulty, H; Strain, JJ; Ward, M	1
Brouwer-Brolsma, EM; de Groot, LC; de Jonge, R; Dhonukshe-Rutten, RA; Enneman, AW; Ham, AC; Lips, P; Oliai Araghi, S; Sohl, E; Stricker, BH; Swart, KM; Uitterlinden, AG; van der Cammen, TJ; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Meurs, JB; van Schoor, NM; van Wijngaarden, JP; Witkamp, RF; Zillikens, MC	1
Adebusoye, LA; Alonge, TO; Ebesunun, MO; Umahoin, KO	1
Dong, W; Gui, L; Guo, J; He, Y; Ma, Y; Sun, L; Zhang, Y; Zong, Y	1
Brouwer-Brolsma, EM; de Groot, LC; Dhonukshe-Rutten, RA; Enneman, AW; Ham, AC; Lips, P; Swart, KM; Uitterlinden, AG; van der Cammen, TJ; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Meurs, J; van Schoor, NM; van Wijngaarden, JP; Zillikens, MC	1
Bailey, RL; Eicher-Miller, HA; Fakhouri, TH; Fan, R; Gahche, JJ; Looker, AC; Lu, Z; Mills, JL; Weaver, CM	1
Brodsky, JL; Coughlin, C; Ficicioglu, C; Freehauf, CL; Kaplan, P; Levine, MA; Lindstrom, K; Weber, DR	1
Yamauchi, M	1
Bala, J; Behera, J; Nuru, M; Tyagi, N; Tyagi, SC	1
Garcia, P; Herrmann, M; Herrmann, W; Hübner, U; Ross, S; Schorr, H; Taban-Shomal, O; Tami, A; Umanskaya, N; Wagner, A; Wildemann, B; Wolny, M	1
Shevchenko, OP	1
Biri, A; Bozkurt, M; Bozkurt, N; Erdem, A; Erdem, M; Kubatova, A; Yilmaz, E	1
Levasseur, R	1
Blom, HJ; Bravenboer, N; de Groot, LC; de Vries, TJ; Dhonukshe-Rutten, RA; Everts, V; Lute, C; Müller, M; Steegenga, WT; Vaes, BL	1
Saito, M	4
Chun, S; Chung, SJ; Kim, BJ; Kim, GS; Kim, HK; Kim, MJ; Kim, SR; Koh, JM; Lee, MC; Lee, SH; Ryu, JS	1
Escobedo, JO; Lim, S; Samoei, GK; Sibrian-Vazquez, M; Strongin, RM	1
Andersson, I; Bosaeus, I; Grönberg, A; Larsson, S; Slinde, F	1
Higuchi, T; Kuroda, T; Saito, M; Shiraki, M; Shiraki, Y; Tanaka, S	1
Bader, R; Bucciarelli, P; Ceccarelli, E; Franci, B; Gennari, L; Mannucci, PM; Martinelli, I; Martini, G; Nuti, R; Valenti, R	1
Abe, K; Higuchi, T; Iino, K; Mizunuma, H; Nakaji, S; Taniguchi, R; Tarakida, A	1
Fleming, JT; Tyagi, N; Tyagi, SC; Vacek, JC; Vacek, TP	1
Kandel, M; Metreveli, N; Munjal, C; Pushpakumar, SB; Qipshidze, N; Tyagi, N; Tyagi, SC; Vacek, JC	1
Che, T; Chen, Y; Lv, H; Ma, X	1
Suzuki, A	1
Cho, CS; Kim, KJ; Kim, WU; Oh, IH; Park, SJ	1
Ahn, SH; Bae, SJ; Choe, JW; Kim, BJ; Kim, EH; Kim, GS; Kim, HK; Kim, SY; Kim, TH; Koh, JM; Lee, SH; Lim, KH; Pyun, KH	1
Gamsjaeger, S; Klaushofer, K; Paschalis, EP; Rumpler, M; Spitzer, S; Thaler, R; Varga, F; Zwerina, J	1
Chin A Paw, MJ; De Groot, LC; de Jong, N; Dhonukshe-Rutten, RA; Hiddink, GJ; Lips, M; van Dusseldorp, M; van Staveren, WA	1
Bathum, L; Christensen, K; Christiansen, L; Madsen, JS; Skytthe, A; von Bornemann Hjelmborg, J	1
Berg, S; Evrin, PE; Johansson, B; McClearn, G; Nilsson, SE; Takkinen, S; Tryding, N	1
Breteler, MM; de Groot, LC; de Jonge, R; Dhonukshe-Rutten, RA; Hofman, A; Lindemans, J; Lips, P; Pluijm, SM; Pols, HA; Uitterlinden, AG; van der Klift, M; van Leeuwen, JP; van Meurs, JB; Witteman, JC	1
Broe, KE; Cupples, LA; Hannan, MT; Jacques, PF; Kiel, DP; McLean, RR; Samelson, EJ; Selhub, J; Tucker, KL	1
Raisz, LG	1
Blackburn, GL	1
Auer, J; Eber, B; Lamm, G	1
Bursztyn, M	1
Arranz-Peña, ML; Luis, DD; Pérez-Castrillón, JL	1
Ellenberg, SS; Orloff, DG; Temple, RJ	1
Cashman, KD	1
de Groot, LC; Dhonukshe-Rutten, RA; Lips, P; Pluijm, SM; Smit, JH; van Staveren, WA	1
Jacques, PF; Morris, MS; Selhub, J	1
Herrmann, M; Herrmann, W; Widmann, T	1
Alscher, DM; Benzinger, P	1
Iwamoto, J; Kanoko, T; Sato, Y; Satoh, K	1
Celik, A; Ciçek, HK; Kepkep, N; Meram, I; Yilmaz, N	1
Belmaker, RH; Levine, J	1
Bjelland, I; Gjesdal, CG; Nurk, E; Nygård, O; Refsum, H; Smith, AD; Tell, GS; Tverdal, A; Ueland, PM; Vollset, SE	1
Kim, DJ; Kim, GS; Kim, HH; Kim, YS; Koh, JM; Lee, KU; Lee, YS; Park, JY	1
Fujii, K; Marumo, K; Saito, M	1
Elliott, JO; Haneef, Z; Jacobson, MP	1
Herrmann, M; Herrmann, W; Obeid, R	1
Gjesdal, CG; Meyer, HE; Refsum, H; Tell, GS; Ueland, PM; Vollset, SE	1
Kitchin, B; Morgan, SL	1
Biagini, MR; Bongini, E; Capanni, M; Galli, A; Milani, S; Surrenti, C; Tozzi, A	1
Hannan, MT; McLean, RR	1
Herrmann, M; Herrmann, W; Lanzer, G; Lenhart, M; Menke, W; Peter Schmidt, J; Schmidt-Gayk, H; Traber, L; Umanskaya, N	1
Alley, RA; Beyer, TD; Chen, EL; Prinz, RA	1
Cupples, LA; Fredman, L; Hannan, MT; Jacques, PF; Kiel, DP; McLean, RR; Samelson, EJ; Selhub, J; Tucker, KL	1
Blom, HJ; Boers, GH; Fang-Kircher, S; Lubec, B; Lubec, T	1

Reviews

21 review(s) available for homocysteine and Osteoporosis

Article	Year
B vitamins and homocysteine as determinants of bone health: A literature review of human studies. Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2023, Volume: 36, Issue:3 Topics: Bone and Bones; Bone Density; Folic Acid; Fractures, Bone; Homocysteine; Humans; Osteoporosis; Vitamin B 12; Vitamin B Complex	2023
Genetically predicted circulating serum homocysteine levels on osteoporosis: a two-sample mendelian randomization study. Scientific reports, 2023, 06-04, Volume: 13, Issue:1 Topics: Bone Density; Genome-Wide Association Study; Homocysteine; Humans; Mendelian Randomization Analysis; Osteoporosis; Polymorphism, Single Nucleotide	2023
Homocysteine: Its Possible Emerging Role in At-Risk Population Groups. International journal of molecular sciences, 2020, Feb-20, Volume: 21, Issue:4 Topics: Aging; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Cardiovascular Diseases; Female; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Neurodegenerative Diseases; Osteoporosis; Pre-Eclampsia; Pregnancy; Risk Factors	2020
The Effects of Homocysteine on the Skeleton. Current osteoporosis reports, 2018, Volume: 16, Issue:5 Topics: Bone and Bones; Collagen; Folic Acid Deficiency; Glycation End Products, Advanced; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Osteoblasts; Osteoclasts; Osteoporosis; Polymorphism, Genetic; Psychotic Disorders; Vitamin B Deficiency	2018
The role of homocysteine in bone remodeling. Clinical chemistry and laboratory medicine, 2013, Mar-01, Volume: 51, Issue:3 Topics: Bone Remodeling; Collagen; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinases; Mitochondria; Osteoporosis; Oxidative Stress	2013
B-vitamins and bone in health and disease: the current evidence. The Proceedings of the Nutrition Society, 2014, Volume: 73, Issue:2 Topics: Bone and Bones; Bone Density; Celiac Disease; Folic Acid; Fractures, Bone; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Osteoporosis; Polymorphism, Single Nucleotide; Vitamin B Complex; Vitamin B Deficiency	2014
[The assessment of bone quality in lifestyle-related diseases]. Clinical calcium, 2016, Volume: 26, Issue:1 Topics: Arginine; Biomarkers; Bone and Bones; Bone Remodeling; Collagen; Diabetes Mellitus, Type 2; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Lysine; Osteoporosis; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Risk; Tomography, X-Ray Computed	2016
Homocysteine as a Pathological Biomarker for Bone Disease. Journal of cellular physiology, 2017, Volume: 232, Issue:10 Topics: Animals; Biomarkers; Bone and Bones; Bone Remodeling; Chondrocytes; Collagen; Disease Progression; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinases; Mitochondria; Osteoclasts; Osteogenesis; Osteoporosis; Oxidative Stress; Regional Blood Flow	2017
Bone tissue and hyperhomocysteinemia. Joint bone spine, 2009, Volume: 76, Issue:3 Topics: Animals; Bone and Bones; Bone Density; Bone Remodeling; Disease Models, Animal; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Osteoporosis	2009
[Biochemical markers of bone turnover. New aspect. Bone collagen metabolism: new biological markers for estimation of bone quality]. Clinical calcium, 2009, Volume: 19, Issue:8 Topics: Arginine; Biomarkers; Bone and Bones; Bone Density; Bone Remodeling; Bone Resorption; Collagen; Glycation End Products, Advanced; Homocysteine; Humans; Lysine; Osteoporosis; Oxidative Stress	2009
[Poor bone quality in diabetes and arterioscelerosis]. Clinical calcium, 2009, Volume: 19, Issue:9 Topics: Animals; Arginine; Arteriosclerosis; Biomarkers; Bone Density; Collagen; Diabetes Complications; Diabetes Mellitus; Fractures, Bone; Glycation End Products, Advanced; Homocysteine; Humans; Lysine; Osteoporosis; Risk	2009
[Bone quality markers: pentosidine, homocysteine, and MTHFR polymorphism]. Rinsho byori. The Japanese journal of clinical pathology, 2009, Volume: 57, Issue:9 Topics: Arginine; Biomarkers; Female; Homocysteine; Humans; Lysine; Methylenetetrahydrofolate Reductase (NADPH2); Osteoporosis; Polymorphism, Genetic	2009
[CKD-MBD (Chronic Kidney Disease-Mineral and Bone Disorder). Bone quality in chronic kidney disease : enzymatic and non-enzymatic glycation or oxidation induced cross-links in bone]. Clinical calcium, 2010, Volume: 20, Issue:7 Topics: Animals; Arginine; Bone and Bones; Bone Diseases, Metabolic; Chronic Disease; Collagen; Fractures, Bone; Glycation End Products, Advanced; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Lysine; Osteoporosis; Oxidative Stress; Risk	2010
[Is bone biopsy necessary for the diagnosis of metabolic bone diseases? Non- invasive assessment of bone turn over markers could define the cause of metabolic bone diseases]. Clinical calcium, 2011, Volume: 21, Issue:9 Topics: Acid Phosphatase; Alkaline Phosphatase; Arginine; Biomarkers; Biopsy; Bone and Bones; Bone Diseases, Metabolic; Collagen Type I; Diagnosis, Differential; Homocysteine; Humans; Isoenzymes; Lysine; Osteoporosis; Peptide Fragments; Peptides; Procollagen; Tartrate-Resistant Acid Phosphatase	2011
Homocysteine and osteoporotic fracture risk: a potential role for B vitamins. Nutrition reviews, 2005, Volume: 63, Issue:1 Topics: Bone and Bones; Fractures, Bone; Genotype; Homocysteine; Humans; Osteoporosis; Risk Factors; Vitamin B Complex	2005
Homocysteine--a newly recognised risk factor for osteoporosis. Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:10 Topics: Animals; Bone and Bones; Bone Density; Homocysteine; Homocystinuria; Humans; Osteoporosis; Risk Factors	2005
The Hordaland Homocysteine Study: a community-based study of homocysteine, its determinants, and associations with disease. The Journal of nutrition, 2006, Volume: 136, Issue:6 Suppl Topics: Adult; Aged; Aging; Bone Density; Cardiovascular Diseases; Cognition Disorders; Depression; Disease; Female; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mortality; Norway; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors	2006
Hyperhomocysteinaemia: a critical review of old and new aspects. Current drug metabolism, 2007, Volume: 8, Issue:1 Topics: Age Factors; Cardiovascular Diseases; Female; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors; Sex Factors	2007
Not just calcium and vitamin D: other nutritional considerations in osteoporosis. Current rheumatology reports, 2007, Volume: 9, Issue:1 Topics: Anorexia Nervosa; Bone Density; Diet; Dietary Supplements; Fruit; Homocysteine; Humans; Nutritional Requirements; Osteoporosis; Randomized Controlled Trials as Topic; Vegetables; Vitamin B 12; Vitamin K	2007
B vitamins, homocysteine, and bone disease: epidemiology and pathophysiology. Current osteoporosis reports, 2007, Volume: 5, Issue:3 Topics: Bone Density; Fractures, Bone; Homocysteine; Humans; Osteoporosis; Risk Factors; Vitamin B Complex	2007
[Role of enzymatic cross-links and non-enzymatic cross-link, advanced glycation end products, as a determinant of bone quality in osteoporosis and diabetes]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Nov-28, Volume: 65 Suppl 9 Topics: Bone and Bones; Collagen; Diabetes Mellitus; Femoral Neck Fractures; Glycation End Products, Advanced; Homocysteine; Humans; Osteoporosis; Oxidative Stress; Tensile Strength; Vitamin B 6 Deficiency; Vitamin D Deficiency	2007

Trials

3 trial(s) available for homocysteine and Osteoporosis

Article	Year
Effect of Vitamin B12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial. Calcified tissue international, 2015, Volume: 96, Issue:5 Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Bone Density; Calcaneus; Dietary Supplements; Double-Blind Method; Female; Femur Neck; Folic Acid; Homocysteine; Humans; Male; Osteoporosis; Ultrasonography; Vitamin B 12	2015
Plasma homocysteine, folate, and vitamin B 12 and the risk of hip fracture: the hordaland homocysteine study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:5 Topics: Adult; Aged; Biomarkers; Female; Folic Acid; Follow-Up Studies; Hip Fractures; Homocysteine; Humans; Male; Middle Aged; Osteoporosis; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prospective Studies; Risk Factors; Vitamin B 12	2007
The effect of B-vitamins on biochemical bone turnover markers and bone mineral density in osteoporotic patients: a 1-year double blind placebo controlled trial. Clinical chemistry and laboratory medicine, 2007, Volume: 45, Issue:12 Topics: Aged; Aged, 80 and over; Biomarkers; Bone Density; Bone Remodeling; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Osteoporosis; Placebos; Vitamin B 12; Vitamin B Complex	2007

Other Studies

51 other study(ies) available for homocysteine and Osteoporosis

Article	Year
Serum homocysteine levels are affected by renal function during a 3-year period of minodronate therapy in female osteoporotic patients. Journal of bone and mineral metabolism, 2019, Volume: 37, Issue:2 Topics: Aged; Biomarkers; Bone Density; Bone Density Conservation Agents; Collagen Type I; Diphosphonates; Drug Administration Schedule; Female; Femur Neck; Homocysteine; Humans; Imidazoles; Kidney; Linear Models; Osteoporosis; Peptide Fragments; Peptides; Procollagen	2019
Homocysteine levels are associated with bone resorption in pre-frail and frail Spanish women: The Toledo Study for Healthy Aging. Experimental gerontology, 2018, 07-15, Volume: 108 Topics: Aged; Biomarkers; Bone and Bones; Bone Density; Bone Resorption; Collagen; Female; Frailty; Healthy Aging; Homocysteine; Humans; Linear Models; Multivariate Analysis; Osteogenesis; Osteoporosis; Spain; Vitamin D	2018
Association of high-density lipoprotein, triglycerides, and homocysteine with bone mineral density in young Indian tribal women. Archives of osteoporosis, 2018, 10-10, Volume: 13, Issue:1 Topics: Absorptiometry, Photon; Adult; Asian People; Bone Density; Bone Diseases, Metabolic; Cohort Studies; Female; Femur; Homocysteine; Humans; India; Lipoproteins, HDL; Lumbar Vertebrae; Mass Screening; Middle Aged; Osteoporosis; Population Groups; Premenopause; Risk Factors; Triglycerides; Young Adult	2018
Homocysteine alters the osteoprotegerin/RANKL system in the osteoblast to promote bone loss: pivotal role of the redox regulator forkhead O1. Free radical biology & medicine, 2013, Volume: 61 Topics: Acetylcysteine; Animals; Cells, Cultured; Female; Forkhead Transcription Factors; Homocysteine; Hyperhomocysteinemia; Nerve Tissue Proteins; Osteoblasts; Osteoporosis; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Protein Phosphatase 2; RANK Ligand; Rats; Rats, Sprague-Dawley	2013
Unique features of non-obstructive emphysema and pure airway obstruction. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2014, Volume: 18, Issue:1 Topics: Adult; Aged; Airway Obstruction; Biomarkers; Body Mass Index; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hypoalbuminemia; Leukocyte Count; Logistic Models; Lung; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Osteoporosis; Pulmonary Emphysema; Republic of Korea; Respiratory Function Tests; Retrospective Studies; Risk Factors; Serum Albumin; Serum Albumin, Human; Tomography, X-Ray Computed	2014
Associations between medication use and homocysteine levels in an older population, and potential mediation by vitamin B12 and folate: data from the B-PROOF Study. Drugs & aging, 2014, Volume: 31, Issue:8 Topics: Aged; Diuretics; Female; Folic Acid; Health Services for the Aged; Homocysteine; Humans; Male; Metformin; Netherlands; Osteoporosis; Population Surveillance; Vitamin B 12; Vitamin B 12 Deficiency	2014
Plasma homocysteine, B vitamins and bone mineral density in osteoporosis: a possible risk for bone fracture. African journal of medicine and medical sciences, 2014, Volume: 43, Issue:1 Topics: Body Mass Index; Bone Density; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nigeria; Osteoporosis; Osteoporotic Fractures; Risk Factors; Vitamin B 12; Vitamin B 6	2014
17β-estradiol attenuates homocysteine-induced oxidative stress and inflammatory response as well as MAPKs cascade via activating PI3-K/Akt signal transduction pathway in Raw 264.7 cells. Acta biochimica et biophysica Sinica, 2015, Volume: 47, Issue:2 Topics: Animals; Cell Survival; Estradiol; Homocysteine; Inflammation; Interleukin-1beta; MAP Kinase Signaling System; Mice; Osteoporosis; Oxidative Stress; Phosphatidylinositol 3-Kinases; RAW 264.7 Cells; Reactive Oxygen Species; RNA, Messenger; Tumor Necrosis Factor-alpha	2015
B-vitamin status and bone mineral density and risk of lumbar osteoporosis in older females in the United States. The American journal of clinical nutrition, 2015, Volume: 102, Issue:3 Topics: Absorptiometry, Photon; Aged; Biomarkers; Bone Density; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Methylmalonic Acid; Middle Aged; Nutrition Surveys; Nutritional Status; Osteoporosis; Risk Factors; United States; Vitamin B Complex	2015
Low bone mineral density is a common finding in patients with homocystinuria. Molecular genetics and metabolism, 2016, Volume: 117, Issue:3 Topics: Absorptiometry, Photon; Adolescent; Adult; Bone Density; Child; Child, Preschool; Female; Homocysteine; Homocystinuria; Humans; Lumbar Vertebrae; Male; Methionine; Middle Aged; Osteoporosis; Retrospective Studies; Young Adult	2016
Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone. Bone, 2009, Volume: 44, Issue:3 Topics: Aged; Animals; Bone and Bones; Collagen; Female; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methionine; Myocardium; Osteoporosis; Porosity; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Stress, Mechanical	2009
[Homocysteine and its role in clinical practice (a lecture)]. Klinicheskaia laboratornaia diagnostika, 2008, Issue:11 Topics: Biomarkers; Clinical Chemistry Tests; Diabetes Mellitus; Female; Gastrointestinal Diseases; History, 20th Century; History, 21st Century; Homocysteine; Humans; Hyperhomocysteinemia; Hyperthyroidism; Kidney Diseases; Mental Disorders; Osteoporosis; Pregnancy; Pregnancy Complications, Cardiovascular	2008
The relationship of homocyteine, B12 and folic acid with the bone mineral density of the femur and lumbar spine in Turkish postmenopausal women. Archives of gynecology and obstetrics, 2009, Volume: 280, Issue:3 Topics: Absorptiometry, Photon; Adult; Aged; Bone Density; Cross-Sectional Studies; Female; Femur; Folic Acid; Homocysteine; Humans; Lumbar Vertebrae; Middle Aged; Osteoporosis; Postmenopause; Turkey; Vitamin B 12	2009
Vitamin B(12) deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid. Calcified tissue international, 2009, Volume: 84, Issue:5 Topics: Animals; Bone and Bones; Bone Density; Bone Remodeling; Cell Differentiation; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Homocysteine; Humans; Male; Methylmalonic Acid; Mice; Mice, Inbred C57BL; Osteoclasts; Osteoporosis; Up-Regulation; Vitamin B 12; Vitamin B 12 Deficiency	2009
Hyperhomocysteinemia due to levodopa treatment as a risk factor for osteoporosis in patients with Parkinson's disease. Calcified tissue international, 2010, Volume: 86, Issue:2 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Bone and Bones; Bone Density; Causality; Cohort Studies; Comorbidity; Female; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Osteoporosis; Prevalence; Risk Factors; Up-Regulation	2010
Homocystamides promote free-radical and oxidative damage to proteins. Proceedings of the National Academy of Sciences of the United States of America, 2010, Jan-12, Volume: 107, Issue:2 Topics: Alzheimer Disease; Cardiovascular Diseases; Congenital Abnormalities; Free Radicals; Homocysteine; Humans; Hydrogen Bonding; Kinetics; Lysine; Osteoporosis; Oxidative Stress; Protein Processing, Post-Translational; Renal Insufficiency; Serum Albumin	2010
Vitamin and mineral status in elderly patients with chronic obstructive pulmonary disease. The clinical respiratory journal, 2007, Volume: 1, Issue:1 Topics: Aged; Aged, 80 and over; Calcium; Diet; Dietary Proteins; Energy Intake; Fatty Acids; Fatty Acids, Unsaturated; Female; Folic Acid; Homocysteine; Humans; Interviews as Topic; Male; Malonates; Minerals; Osteoporosis; Pulmonary Disease, Chronic Obstructive; Vitamin D; Vitamins	2007
Urinary pentosidine and plasma homocysteine levels at baseline predict future fractures in osteoporosis patients under bisphosphonate treatment. Journal of bone and mineral metabolism, 2011, Volume: 29, Issue:1 Topics: Aged; Arginine; Bone Density; Bone Density Conservation Agents; Diphosphonates; Female; Fractures, Bone; Homocysteine; Humans; Lysine; Middle Aged; Osteoporosis; Proportional Hazards Models	2011
The relationship between plasma homocysteine levels and bone mineral density in post-menopausal women. European journal of internal medicine, 2010, Volume: 21, Issue:4 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Body Mass Index; Bone Density; Chi-Square Distribution; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Italy; Linear Models; Menopause; Middle Aged; Osteoporosis; Vitamin B 12	2010
Hypercholesterolemia accelerates bone loss in postmenopausal women. Climacteric : the journal of the International Menopause Society, 2011, Volume: 14, Issue:1 Topics: Adult; Calcaneus; Cholesterol; Cytokines; Densitometry; Female; Homocysteine; Humans; Hypercholesterolemia; Japan; Middle Aged; Osteoporosis; Postmenopause; Premenopause; Triglycerides; Ultrasonography	2011
Hyperhomocysteinemia decreases bone blood flow. Vascular health and risk management, 2011, Jan-25, Volume: 7 Topics: Animals; Biomarkers; Biomechanical Phenomena; Blood Pressure; Bone Density; Bone Remodeling; Disease Models, Animal; Folic Acid; Homocysteine; Hyperhomocysteinemia; Laser-Doppler Flowmetry; Male; Osteoporosis; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tibia; Time Factors; Up-Regulation; Vitamin B 12	2011
Homocysteine mediated decrease in bone blood flow and remodeling: role of folic acid. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2011, Volume: 29, Issue:10 Topics: Animals; Bone Density; Bone Remodeling; Folic Acid; Homocysteine; Hyperhomocysteinemia; Matrix Metalloproteinase 9; Mice; Nitric Oxide; Osteoporosis; Oxidative Stress; Regional Blood Flow; Tibia; Tibial Arteries	2011
Methylation of the promoter A of estrogen receptor alpha gene in hBMSC and osteoblasts and its correlation with homocysteine. Molecular and cellular biochemistry, 2011, Volume: 355, Issue:1-2 Topics: Adult; Age Factors; Aged; Bone Density; Bone Marrow Cells; Cell Differentiation; Cell Lineage; Cell Proliferation; DNA Methylation; Estrogen Receptor alpha; Female; Gene Expression Regulation; Homocysteine; Humans; Middle Aged; Osteoblasts; Osteoporosis; Postmenopause; Premenopause; Promoter Regions, Genetic; Stem Cells; Transcription, Genetic; Young Adult	2011
Involvement of endoplasmic reticulum stress in homocysteine-induced apoptosis of osteoblastic cells. Journal of bone and mineral metabolism, 2012, Volume: 30, Issue:4 Topics: Apoptosis; Caspase 3; Caspase Inhibitors; Cell Line; Cell Survival; Cells, Cultured; Endoplasmic Reticulum Stress; Endoribonucleases; Gene Silencing; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Molecular Targeted Therapy; Organ Specificity; Osteoarthritis, Knee; Osteoblasts; Osteoporosis; Protein Serine-Threonine Kinases; RNA, Small Interfering; Synovial Membrane	2012
High serum total homocysteine levels accelerate hip bone loss in healthy premenopausal women and men. Bone, 2013, Volume: 52, Issue:1 Topics: Adult; Bone Density; Female; Hip; Homocysteine; Humans; Life Style; Male; Middle Aged; Osteoporosis; Premenopause; Reference Values; Republic of Korea	2013
Homocysteine induces serum amyloid A3 in osteoblasts via unlocking RGD-motifs in collagen. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:2 Topics: 3T3 Cells; Animals; Base Sequence; beta Catenin; Cell Line; Chemokine CCL5; Collagen Type I; Extracellular Matrix; fas Receptor; Focal Adhesion Kinase 1; Gene Expression; Homocysteine; Humans; Hyperhomocysteinemia; Matrix Metalloproteinase 13; Mice; Models, Biological; Oligopeptides; Osteoblasts; Osteoporosis; Paxillin; Protein Denaturation; RNA, Messenger; RNA, Small Interfering; Serum Amyloid A Protein; Signal Transduction	2013
Vitamin B-12 status is associated with bone mineral content and bone mineral density in frail elderly women but not in men. The Journal of nutrition, 2003, Volume: 133, Issue:3 Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Body Composition; Body Height; Body Weight; Bone Density; Calcium, Dietary; Female; Frail Elderly; Homocysteine; Humans; Male; Methylmalonic Acid; Netherlands; Nutritional Status; Odds Ratio; Osteoporosis; Parathyroid Hormone; Regression Analysis; Sex Characteristics; Smoking; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D	2003
Evidence for an association of methylene tetrahydrofolate reductase polymorphism C677T and an increased risk of fractures: results from a population-based Danish twin study. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2004, Volume: 15, Issue:8 Topics: Aged; Denmark; Female; Fractures, Bone; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Osteoporosis; Polymorphism, Genetic; Population Surveillance; Risk Factors; Twins	2004
Association of biochemical values with morbidity in the elderly: a population-based Swedish study of persons aged 82 or more years. Scandinavian journal of clinical and laboratory investigation, 2003, Volume: 63, Issue:7-8 Topics: Aged; Aged, 80 and over; Biomarkers; Blood Chemical Analysis; Body Mass Index; Cholesterol; Creatine; Data Interpretation, Statistical; Female; Furosemide; gamma-Glutamyltransferase; Gout; Heart Failure; Hip Fractures; Homocysteine; Humans; Linear Models; Male; Morbidity; Osteoporosis; Peptic Ulcer; Serum Albumin; Sex Factors; Sweden; Twins; Urea; Uric Acid	2003
Homocysteine levels and the risk of osteoporotic fracture. The New England journal of medicine, 2004, May-13, Volume: 350, Issue:20 Topics: Aged; Bone Density; Cohort Studies; Female; Follow-Up Studies; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Osteoporosis; Proportional Hazards Models; Risk; Risk Factors	2004
Homocysteine as a predictive factor for hip fracture in older persons. The New England journal of medicine, 2004, May-13, Volume: 350, Issue:20 Topics: Aged; Aged, 80 and over; Female; Follow-Up Studies; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Osteoporosis; Proportional Hazards Models; Risk Factors	2004
Homocysteine and osteoporotic fractures--culprit or bystander? The New England journal of medicine, 2004, May-13, Volume: 350, Issue:20 Topics: Estradiol; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors	2004
A new risk factor for fractures? Diets low in B vitamins may leave people more prone to broken bones. Health news (Waltham, Mass.), 2004, Volume: 10, Issue:7 Topics: Female; Fractures, Bone; Homocysteine; Humans; Male; Middle Aged; Osteoporosis; Risk Factors; Vitamin B Complex	2004
Homocysteine as a predictive factor for hip fracture in older persons. The New England journal of medicine, 2004, Sep-02, Volume: 351, Issue:10 Topics: Aged; Bone Density; Confounding Factors, Epidemiologic; Exercise; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors	2004
Homocysteine as a predictive factor for hip fracture in older persons. The New England journal of medicine, 2004, Sep-02, Volume: 351, Issue:10 Topics: Aged; Aging; Creatinine; Glomerular Filtration Rate; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors	2004
Homocysteine as a predictive factor for hip fracture in older persons. The New England journal of medicine, 2004, Sep-02, Volume: 351, Issue:10 Topics: Aged; Aging; Bone Density; Folic Acid Deficiency; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Risk Factors; Vitamin B Deficiency	2004
Homocysteine as a predictive factor for hip fracture in older persons. The New England journal of medicine, 2004, Sep-02, Volume: 351, Issue:10 Topics: Aged; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Osteoporosis; Randomized Controlled Trials as Topic; Research Design; Risk Factors	2004
Coffee: for most, it's safe. Coffee has been blamed for everything from moral turpitude to cancer. But none of the bad raps have stuck. Coffee may even be good for you. Harvard women's health watch, 2004, Volume: 12, Issue:1 Topics: Caffeine; Cardiovascular System; Coffee; Diabetes Mellitus, Type 2; Female; Homocysteine; Humans; Liver Diseases; Neoplasms; Osteoporosis; Parkinson Disease; Pregnancy	2004
Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:6 Topics: Aged; Aged, 80 and over; Body Weight; Bone and Bones; Cohort Studies; Creatine; Female; Fractures, Bone; Homocysteine; Humans; Immunoassay; Immunoradiometric Assay; Male; Middle Aged; Osteocalcin; Osteoporosis; Proportional Hazards Models; Regression Analysis; Risk; Risk Factors; Time Factors; Ultrasonography; Vitamin B 12	2005
Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans. Bone, 2005, Volume: 37, Issue:2 Topics: Aged; Bone Density; Female; Folic Acid; Hip; Homocysteine; Humans; Male; Methylmalonic Acid; Osteoporosis; Radiography; United States; Vitamin B 12	2005
[Untreated homocystinuria in adulthood]. Deutsche medizinische Wochenschrift (1946), 2005, Oct-28, Volume: 130, Issue:43 Topics: Adult; Age Factors; Angina Pectoris; Betaine; Diagnosis, Differential; Drug Therapy, Combination; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Intervertebral Disc Displacement; Lens Subluxation; Male; Marfan Syndrome; Myopia; Osteoporosis; Retinal Detachment; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2005
RETRACTED: Homocysteine as a predictive factor for hip fracture in elderly women with Parkinson's disease. The American journal of medicine, 2005, Volume: 118, Issue:11 Topics: Accidental Falls; Aged; Antiparkinson Agents; Cohort Studies; Female; Follow-Up Studies; Fractures, Spontaneous; Hip Fractures; Homocysteine; Humans; Hyperhomocysteinemia; Immobilization; Incidence; Japan; Levodopa; Osteoporosis; Parkinson Disease; Proportional Hazards Models; Risk Factors	2005
Relation of parity and homocysteine to bone mineral density of postmenopausal women. Clinical laboratory, 2006, Volume: 52, Issue:1-2 Topics: Absorptiometry, Photon; Amino Acids; Blood Chemical Analysis; Bone Density; Developing Countries; Female; Homocysteine; Humans; Lumbosacral Region; Middle Aged; Osteoporosis; Parity; Postmenopause; Pregnancy; Turkey	2006
Osteoporosis and schizophrenia. The American journal of psychiatry, 2006, Volume: 163, Issue:3 Topics: Bone Density; Comorbidity; Female; Fractures, Bone; Homocysteine; Humans; Male; Osteoporosis; Schizophrenia; Sex Factors	2006
Homocysteine enhances bone resorption by stimulation of osteoclast formation and activity through increased intracellular ROS generation. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2006, Volume: 21, Issue:7 Topics: Acid Phosphatase; Animals; Bone Marrow Cells; Bone Resorption; Cell Differentiation; Cells, Cultured; Fractures, Bone; Homocysteine; Hyperhomocysteinemia; Isoenzymes; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Osteoclasts; Osteoporosis; Protein Kinases; Reactive Oxygen Species; Risk Factors; Tartrate-Resistant Acid Phosphatase	2006
Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls. Calcified tissue international, 2006, Volume: 79, Issue:3 Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Calcification, Physiologic; Calcium; Collagen; Female; Femur Neck; Hip Fractures; Homocysteine; Humans; Osteoporosis; Phosphorus; Spectrophotometry, Atomic; Vitamin B 6	2006
Homocysteine and bone loss in epilepsy. Seizure, 2007, Volume: 16, Issue:1 Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anticonvulsants; Blood Urea Nitrogen; Bone Density; Bone Diseases, Metabolic; Calcium; Epilepsy; Female; Folic Acid; Hip; Homocysteine; Humans; Male; Middle Aged; Osteoporosis; Regression Analysis; Spine	2007
Association of plasma homocysteine with bone mineral density in postmenopausal women with osteoporosis or osteopenia affected by primary biliary cirrhosis. Journal of clinical gastroenterology, 2007, Volume: 41, Issue:6 Topics: Aged; Bone Density; Bone Diseases, Metabolic; Female; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis, Biliary; Middle Aged; Osteoporosis; Risk Factors	2007
Does homocysteine contribute to bone disease in hyperparathyroidism? American journal of surgery, 2008, Volume: 195, Issue:3 Topics: Biomarkers; Bone and Bones; Bone Density; Female; Homocysteine; Humans; Hyperhomocysteinemia; Hyperparathyroidism; Kidney Diseases; Male; Middle Aged; Osteoporosis; Parathyroidectomy; Prospective Studies	2008
Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and women. The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:6 Topics: Adult; Aged; Female; Follow-Up Studies; Hip Fractures; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Osteoporosis; Residence Characteristics; Risk Factors; Vitamin B Complex	2008
Evidence for McKusick's hypothesis of deficient collagen cross-linking in patients with homocystinuria. Biochimica et biophysica acta, 1996, Apr-12, Volume: 1315, Issue:3 Topics: Adult; Biomarkers; Child; Child, Preschool; Collagen; Collagen Type I; Cystathionine beta-Synthase; Female; Homocysteine; Homocystinuria; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Models, Biological; Osteoporosis; Oxidoreductases Acting on CH-NH Group Donors; Peptide Fragments; Peptides; Procollagen; Protein Processing, Post-Translational; Solubility	1996