hydrochlorothiazide has been researched along with Osteoporosis in 22 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In six women with postmenopausal osteoporosis, most of whom responded to 50 micrograms/day 25-hydroxyvitamin D (25-OHD) therapy with a rise in intestinal calcium (Ca) absorption, 50 mg/day hydrochlorothiazide (TZ) were added to determine whether the resulting decline in urinary Ca would cause Ca retention in the skeleton." | 7.67 | Reduction in intestinal calcium absorption by hydrochlorothiazide in postmenopausal osteoporosis. ( Glass, K; Nicar, MJ; Pak, CY; Sakhaee, K; Zerwekh, JE, 1984) |
| " Treatments were as follows: idiopathic osteoporosis: calcium and vitamin D supplements (N = 10) or cyclical etidronate for 2 weeks followed by calcium and vitamin D supplements for 76 days (N = 29); moderate idiopathic phosphate diabetes: calcitriol and phosphate (N = 15); idiopathic hypercalciuria: hydrochlorothiazide (N = 6); and hypogonadism: testosterone (N = 3)." | 5.09 | Management of male osteoporosis. ( Catanzariti, L; Cortet, B; Delcambre, B; Grardel, B; Marchandise, X; Vasseur, J, 2001) |
| "In six women with postmenopausal osteoporosis, most of whom responded to 50 micrograms/day 25-hydroxyvitamin D (25-OHD) therapy with a rise in intestinal calcium (Ca) absorption, 50 mg/day hydrochlorothiazide (TZ) were added to determine whether the resulting decline in urinary Ca would cause Ca retention in the skeleton." | 3.67 | Reduction in intestinal calcium absorption by hydrochlorothiazide in postmenopausal osteoporosis. ( Glass, K; Nicar, MJ; Pak, CY; Sakhaee, K; Zerwekh, JE, 1984) |
| "Hydrochlorothiazide treatment in hypercalciuric and osteoporotic men was associated with a rapid rebound increase in bone mineral density." | 1.30 | Rapid recovery of bone mass in hypercalciuric, osteoporotic men treated with hydrochlorothiazide. ( Adams, JS; Kantorovich, V; Song, CF, 1999) |
| "Treatment with hydrochlorothiazide (50 mg/day) produced a decline in fasting urinary Ca (to 0." | 1.27 | Postmenopausal osteoporosis as a manifestation of renal hypercalciuria with secondary hyperparathyroidism. ( Glass, K; Nicar, MJ; Pak, CY; Sakhaee, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (40.91) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ábalos-Medina, GM | 1 |
| Fernández Rodríguez, I | 1 |
| del Mar Almagro Ratia, M | 1 |
| Fuentes Ellauri, MA | 1 |
| Arrabal-Polo, MA | 1 |
| Arias-Santiago, S | 1 |
| de Haro-Muñoz, T | 1 |
| Lopez-Ruiz, A | 1 |
| Orgaz-Molina, J | 1 |
| Gonzalez-Torres, S | 1 |
| Zuluaga-Gomez, A | 1 |
| Arrabal-Martin, M | 1 |
| Sakhaee, K | 2 |
| Nicar, MJ | 2 |
| Glass, K | 2 |
| Zerwekh, JE | 1 |
| Pak, CY | 3 |
| Torgerson, DJ | 1 |
| Ryan, M | 1 |
| Ratcliffe, J | 1 |
| Jergas, M | 1 |
| Kosow, A | 1 |
| Uffmann, M | 1 |
| Schmutz, G | 1 |
| Böckenförde, JB | 1 |
| Glüer, CC | 1 |
| Köster, O | 1 |
| Reusz, G | 1 |
| Adams, JS | 1 |
| Song, CF | 1 |
| Kantorovich, V | 1 |
| Frassetto, LA | 1 |
| Nash, E | 1 |
| Morris, RC | 1 |
| Sebastian, A | 1 |
| LaCroix, AZ | 1 |
| Ott, SM | 1 |
| Ichikawa, L | 1 |
| Scholes, D | 1 |
| Barlow, WE | 1 |
| Simöes, A | 1 |
| Domingos, F | 1 |
| Fortes, A | 1 |
| Prata, MM | 1 |
| Cortet, B | 1 |
| Vasseur, J | 1 |
| Grardel, B | 1 |
| Catanzariti, L | 1 |
| Marchandise, X | 1 |
| Delcambre, B | 1 |
| Kamel, HK | 1 |
| Wong, CK | 1 |
| Pun, KK | 1 |
| Tam, SC | 1 |
| Tsui, EY | 1 |
| Kung, AW | 1 |
| Lam, KS | 1 |
| Wang, CC | 1 |
| Kocián, J | 1 |
| Grajek, S | 1 |
| Raszeja-Wanic, B | 1 |
| Harrison, JE | 1 |
| Hitchman, AJ | 1 |
| Finlay, JM | 1 |
| Fraser, D | 1 |
| Yendt, ER | 1 |
| Bayley, TA | 1 |
| McNeill, KG | 1 |
| Ruskin, B | 1 |
| Diller, E | 1 |
| Griffith, DP | 2 |
| Donath, A | 1 |
| Nordio, S | 1 |
| Macagno, F | 1 |
| Gatti, R | 1 |
2 reviews available for hydrochlorothiazide and Osteoporosis
| Article | Year |
|---|---|
[Idiopathic hypercalciuria in childhood].
Topics: Adolescent; Adult; Aged; Bone Density; Calcium; Calcium, Dietary; Child; Child, Preschool; Diet, Sod | 1998 |
Idiopathic hypercalciuria. Diagnosis and treatment.
Topics: Bone and Bones; Calcium; Diet Therapy; Female; Humans; Hydrochlorothiazide; Kidney; Male; Osteoporos | 1987 |
4 trials available for hydrochlorothiazide and Osteoporosis
| Article | Year |
|---|---|
[The effect of a low-dose hydrochlorothiazide therapy on the bone mineral content of the axial and peripheral skeleton].
Topics: Absorptiometry, Photon; Aged; Bone Density; Drug Therapy, Combination; Estrogen Replacement Therapy; | 1994 |
Comparative effects of potassium chloride and bicarbonate on thiazide-induced reduction in urinary calcium excretion.
Topics: Acid-Base Equilibrium; Acidosis; Aged; Bicarbonates; Calcium; Creatinine; Diuretics; Double-Blind Me | 2000 |
Low-dose hydrochlorothiazide and preservation of bone mineral density in older adults. A randomized, double-blind, placebo-controlled trial.
Topics: Aged; Bone Density; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies | 2000 |
Management of male osteoporosis.
Topics: Absorptiometry, Photon; Bone Density; Calcitriol; Calcium; Dietary Supplements; Etidronic Acid; Femu | 2001 |
16 other studies available for hydrochlorothiazide and Osteoporosis
| Article | Year |
|---|---|
[Mineral and bone disorder associated with Cacchi-Ricci disease].
Topics: Adult; Alendronate; Bone Density Conservation Agents; Bone Remodeling; Calcifediol; Calcium; Drug Th | 2014 |
Effects of aminobisphosphonates and thiazides in patients with osteopenia/osteoporosis, hypercalciuria, and recurring renal calcium lithiasis.
Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Calcium; Fema | 2013 |
Thiazide diuretics and osteoporosis.
Topics: Aged; Bone Density; Diuretics; Humans; Hydrochlorothiazide; Middle Aged; Osteoporosis; Sodium Chlori | 2002 |
Reduction in intestinal calcium absorption by hydrochlorothiazide in postmenopausal osteoporosis.
Topics: Aged; Bone and Bones; Calcifediol; Calcium; Drug Therapy, Combination; Female; Humans; Hydrochloroth | 1984 |
Economics in sample size determination for clinical trials.
Topics: Adult; Aged; Clinical Trials as Topic; Cost-Benefit Analysis; Danazol; Endometriosis; Female; Gosere | 1995 |
Rapid recovery of bone mass in hypercalciuric, osteoporotic men treated with hydrochlorothiazide.
Topics: Aged; Bone Density; Calcium; Chronic Disease; Creatinine; Diuretics; Humans; Hydrochlorothiazide; Mi | 1999 |
Type 1 glycogen storage disease and recurrent calcium nephrolithiasis.
Topics: Absorptiometry, Photon; Adolescent; Allopurinol; Amiloride; Calcinosis; Diet, Sodium-Restricted; Diu | 2001 |
Low-dose thiazide and bone density.
Topics: Aged; Antihypertensive Agents; Bone Density; Calcium; Female; Humans; Hydrochlorothiazide; Kidney Tu | 2002 |
Idiopathic hypercalciuria causing osteoporosis and hypocalcemia.
Topics: Adolescent; Calcitriol; Calcium; Calcium, Dietary; Female; Humans; Hydrochlorothiazide; Hypocalcemia | 1992 |
Postmenopausal osteoporosis as a manifestation of renal hypercalciuria with secondary hyperparathyroidism.
Topics: Aged; Bone and Bones; Calcium; Female; Humans; Hydrochlorothiazide; Hyperparathyroidism, Secondary; | 1985 |
[Effect of hydrochlorothiazide on calcium concentration in serum and urine of patients with primary osteoporosis].
Topics: Aged; Calcium; Humans; Hydrochlorothiazide; Male; Osteoporosis | 1974 |
Effect of treatment on calcium kinetics in metabolic bone disease.
Topics: Adult; Aged; Bone Diseases; Calcium; Calcium Isotopes; Calcium Metabolism Disorders; Child, Preschoo | 1971 |
Enhancement of renal excretion of zinc by hydrochlorothiazide.
Topics: Adolescent; Adult; Calcium; Calcium Metabolism Disorders; Copper; Female; Furosemide; Humans; Hydroc | 1972 |
Immobilization hypercalciuria: treatment and a possible pathophysiologic mechanism.
Topics: Adult; Calcium; Diet, Sodium-Restricted; Extracellular Space; Female; Humans; Hydrochlorothiazide; I | 1971 |
The effect of hydrochlorothiazide and of sodium in the diet on calcium and strontium transport in intestine and kidney.
Topics: Calcium; Diet; Humans; Hydrochlorothiazide; Intestinal Absorption; Kidney; Osteoporosis; Sodium; Str | 1971 |
Control of hypercalciuria in the immobilized patient.
Topics: Adult; Calcium; Calcium Metabolism Disorders; Calcium, Dietary; Diet Therapy; Extracellular Space; F | 1971 |