Compounds > 1,4-dihydroxy-2-naphthoic acid
Page last updated: 2024-09-19

1,4-dihydroxy-2-naphthoic acid

Cross-References

ID SourceID
PubMed CID671
CHEMBL ID1232286
CHEBI ID18094
SCHEMBL ID317180
MeSH IDM0081900

Synonyms (48)

Synonym
CBMICRO_022187
CHEMBL1232286
CHEBI:18094 ,
1,4-dihydroxynaphthalene-2-carboxylic acid
1,4-dihydroxy-2-naphthalenecarboxylic acid
2-naphthalenecarboxylic acid, 1,4-dihydroxy-
2-naphthoic acid, 1,4-dihydroxy-
31519-22-9
C03657 ,
1,4-dihydroxy-2-naphthoic acid ,
1,4-dihydroxy-2-naphthoic acid, 97%
NCGC00164120-01
OPREA1_682770
1F3E7FB2-5745-4C2A-A942-D4AD78D5E1F0
2-naphthoic acid, 1,4-dihydroxy
BMSE000688
vojuxhhacrxltd-uhfffaoysa-
inchi=1/c11h8o4/c12-9-5-8(11(14)15)10(13)7-4-2-1-3-6(7)9/h1-5,12-13h,(h,14,15)
D2296
AKOS000120806
1,4-dihydroxy-2-naphthalic acid
NCGC00255467-01
dtxsid0037730 ,
tox21_301655
cas-31519-22-9
dtxcid8017730
einecs 250-674-7
unii-1u77mr5q7o
1u77mr5q7o ,
FT-0638978
AB00443880-02
SCHEMBL317180
SY014338
mfcd00010370
W-106893
AC-23628
1,4-dihydroxy-2-carboxy naphthoic acid
1,4-dihydroxy-2-naphtoic acid
1,4-dihydroxy-2-naphthoicacid
STL513558
Q27102818
EN300-21490
STR05294
HMS3741M11
H11275
(hydroxypropyl)methylcellulose
Z104500068
PD129222

Roles (1)

RoleDescription
Escherichia coli metaboliteAny bacterial metabolite produced during a metabolic reaction in Escherichia coli.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (4)

ClassDescription
dihydroxy monocarboxylic acidAny hydroxy monocarboxylic acid carrying at least two hydroxy groups.
naphthoic acidAn aromatic carboxylic acid that consists of a naphthalene skeleton substituted by one or more carboxy groups.
naphthalenediolsAny hydroxynaphthalene derivative that has two hydroxy substituents.
naphthohydroquinoneA hydroxynaphthalene that is naphthalene-1,4-diol and its C-substituted derivatives.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

1,4-dihydroxy-2-naphthoic acid is involved in 1 pathway(s), involving a total of 2 unique proteins and 18 unique compounds

PathwayProteinsCompounds
vitamin K1218

Protein Targets (37)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
LuciferasePhotinus pyralis (common eastern firefly)Potency31.70550.007215.758889.3584AID1224835
acetylcholinesteraseHomo sapiens (human)Potency44.78530.002541.796015,848.9004AID1347398
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency12.65143.189029.884159.4836AID1224846; AID1224894
RAR-related orphan receptor gammaMus musculus (house mouse)Potency13.68540.006038.004119,952.5996AID1159521; AID1159523
SMAD family member 2Homo sapiens (human)Potency12.19520.173734.304761.8120AID1346859; AID1346924
SMAD family member 3Homo sapiens (human)Potency12.19520.173734.304761.8120AID1346859; AID1346924
GLI family zinc finger 3Homo sapiens (human)Potency1.79160.000714.592883.7951AID1259369; AID1259392
AR proteinHomo sapiens (human)Potency29.10080.000221.22318,912.5098AID1259243; AID1259247; AID588516; AID743042; AID743054; AID743063
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency68.58960.000657.913322,387.1992AID1259378
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency24.82750.001022.650876.6163AID1224838; AID1224839; AID1224893
progesterone receptorHomo sapiens (human)Potency68.58960.000417.946075.1148AID1346795
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency26.78050.000214.376460.0339AID588533; AID720691; AID720692
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency66.05580.003041.611522,387.1992AID1159552; AID1159555
retinoid X nuclear receptor alphaHomo sapiens (human)Potency28.18380.000817.505159.3239AID588546
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency61.09770.001530.607315,848.9004AID1224841; AID1224848; AID1224849; AID1259401; AID1259403
farnesoid X nuclear receptorHomo sapiens (human)Potency39.66690.375827.485161.6524AID588526; AID743220
pregnane X nuclear receptorHomo sapiens (human)Potency16.77800.005428.02631,258.9301AID1346982; AID720659
estrogen nuclear receptor alphaHomo sapiens (human)Potency33.78240.000229.305416,493.5996AID1259244; AID1259248; AID1259383; AID588513; AID588514; AID743069; AID743079; AID743080; AID743091
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency39.71380.001024.504861.6448AID588535; AID743215
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency39.35290.001019.414170.9645AID588536; AID743191
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency32.40760.023723.228263.5986AID588541; AID743223
aryl hydrocarbon receptorHomo sapiens (human)Potency8.79580.000723.06741,258.9301AID651777; AID743085; AID743122
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency9.68850.001723.839378.1014AID743083
thyroid stimulating hormone receptorHomo sapiens (human)Potency27.72580.001628.015177.1139AID1224843; AID1259385
activating transcription factor 6Homo sapiens (human)Potency1.73740.143427.612159.8106AID1159519
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency15.484519.739145.978464.9432AID1159509
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency1.21450.057821.109761.2679AID1159526; AID1159528
Histone H2A.xCricetulus griseus (Chinese hamster)Potency46.88470.039147.5451146.8240AID1224845; AID1224896
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency81.55610.010039.53711,122.0200AID1469; AID1479; AID588547
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency39.40960.000323.4451159.6830AID743065; AID743067
histone deacetylase 9 isoform 3Homo sapiens (human)Potency31.54560.037617.082361.1927AID1259364; AID1259388
heat shock protein beta-1Homo sapiens (human)Potency15.48450.042027.378961.6448AID743210
nuclear factor NF-kappa-B p105 subunit isoform 1Homo sapiens (human)Potency31.62284.466824.832944.6684AID651749
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency7.49660.000627.21521,122.0200AID651741; AID720636; AID743202; AID743219
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency27.30600.001557.789015,848.9004AID1259244
Cellular tumor antigen p53Homo sapiens (human)Potency42.56030.002319.595674.0614AID651631; AID720552
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency27.30600.001551.739315,848.9004AID1259244
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (124)

Processvia Protein(s)Taxonomy
negative regulation of cell population proliferationCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycleCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycle G2/M phase transitionCellular tumor antigen p53Homo sapiens (human)
DNA damage responseCellular tumor antigen p53Homo sapiens (human)
ER overload responseCellular tumor antigen p53Homo sapiens (human)
cellular response to glucose starvationCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
positive regulation of miRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
negative regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
mitophagyCellular tumor antigen p53Homo sapiens (human)
in utero embryonic developmentCellular tumor antigen p53Homo sapiens (human)
somitogenesisCellular tumor antigen p53Homo sapiens (human)
release of cytochrome c from mitochondriaCellular tumor antigen p53Homo sapiens (human)
hematopoietic progenitor cell differentiationCellular tumor antigen p53Homo sapiens (human)
T cell proliferation involved in immune responseCellular tumor antigen p53Homo sapiens (human)
B cell lineage commitmentCellular tumor antigen p53Homo sapiens (human)
T cell lineage commitmentCellular tumor antigen p53Homo sapiens (human)
response to ischemiaCellular tumor antigen p53Homo sapiens (human)
nucleotide-excision repairCellular tumor antigen p53Homo sapiens (human)
double-strand break repairCellular tumor antigen p53Homo sapiens (human)
regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
protein import into nucleusCellular tumor antigen p53Homo sapiens (human)
autophagyCellular tumor antigen p53Homo sapiens (human)
DNA damage responseCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorCellular tumor antigen p53Homo sapiens (human)
transforming growth factor beta receptor signaling pathwayCellular tumor antigen p53Homo sapiens (human)
Ras protein signal transductionCellular tumor antigen p53Homo sapiens (human)
gastrulationCellular tumor antigen p53Homo sapiens (human)
neuroblast proliferationCellular tumor antigen p53Homo sapiens (human)
negative regulation of neuroblast proliferationCellular tumor antigen p53Homo sapiens (human)
protein localizationCellular tumor antigen p53Homo sapiens (human)
negative regulation of DNA replicationCellular tumor antigen p53Homo sapiens (human)
negative regulation of cell population proliferationCellular tumor antigen p53Homo sapiens (human)
determination of adult lifespanCellular tumor antigen p53Homo sapiens (human)
mRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
rRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
response to salt stressCellular tumor antigen p53Homo sapiens (human)
response to inorganic substanceCellular tumor antigen p53Homo sapiens (human)
response to X-rayCellular tumor antigen p53Homo sapiens (human)
response to gamma radiationCellular tumor antigen p53Homo sapiens (human)
positive regulation of gene expressionCellular tumor antigen p53Homo sapiens (human)
cardiac muscle cell apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic processCellular tumor antigen p53Homo sapiens (human)
glial cell proliferationCellular tumor antigen p53Homo sapiens (human)
viral processCellular tumor antigen p53Homo sapiens (human)
glucose catabolic process to lactate via pyruvateCellular tumor antigen p53Homo sapiens (human)
cerebellum developmentCellular tumor antigen p53Homo sapiens (human)
negative regulation of cell growthCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
negative regulation of transforming growth factor beta receptor signaling pathwayCellular tumor antigen p53Homo sapiens (human)
mitotic G1 DNA damage checkpoint signalingCellular tumor antigen p53Homo sapiens (human)
negative regulation of telomere maintenance via telomeraseCellular tumor antigen p53Homo sapiens (human)
T cell differentiation in thymusCellular tumor antigen p53Homo sapiens (human)
tumor necrosis factor-mediated signaling pathwayCellular tumor antigen p53Homo sapiens (human)
regulation of tissue remodelingCellular tumor antigen p53Homo sapiens (human)
cellular response to UVCellular tumor antigen p53Homo sapiens (human)
multicellular organism growthCellular tumor antigen p53Homo sapiens (human)
positive regulation of mitochondrial membrane permeabilityCellular tumor antigen p53Homo sapiens (human)
cellular response to glucose starvationCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
entrainment of circadian clock by photoperiodCellular tumor antigen p53Homo sapiens (human)
mitochondrial DNA repairCellular tumor antigen p53Homo sapiens (human)
regulation of DNA damage response, signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of neuron apoptotic processCellular tumor antigen p53Homo sapiens (human)
transcription initiation-coupled chromatin remodelingCellular tumor antigen p53Homo sapiens (human)
negative regulation of proteolysisCellular tumor antigen p53Homo sapiens (human)
negative regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
positive regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
positive regulation of RNA polymerase II transcription preinitiation complex assemblyCellular tumor antigen p53Homo sapiens (human)
positive regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
response to antibioticCellular tumor antigen p53Homo sapiens (human)
fibroblast proliferationCellular tumor antigen p53Homo sapiens (human)
negative regulation of fibroblast proliferationCellular tumor antigen p53Homo sapiens (human)
circadian behaviorCellular tumor antigen p53Homo sapiens (human)
bone marrow developmentCellular tumor antigen p53Homo sapiens (human)
embryonic organ developmentCellular tumor antigen p53Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylationCellular tumor antigen p53Homo sapiens (human)
protein stabilizationCellular tumor antigen p53Homo sapiens (human)
negative regulation of helicase activityCellular tumor antigen p53Homo sapiens (human)
protein tetramerizationCellular tumor antigen p53Homo sapiens (human)
chromosome organizationCellular tumor antigen p53Homo sapiens (human)
neuron apoptotic processCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycleCellular tumor antigen p53Homo sapiens (human)
hematopoietic stem cell differentiationCellular tumor antigen p53Homo sapiens (human)
negative regulation of glial cell proliferationCellular tumor antigen p53Homo sapiens (human)
type II interferon-mediated signaling pathwayCellular tumor antigen p53Homo sapiens (human)
cardiac septum morphogenesisCellular tumor antigen p53Homo sapiens (human)
positive regulation of programmed necrotic cell deathCellular tumor antigen p53Homo sapiens (human)
protein-containing complex assemblyCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressCellular tumor antigen p53Homo sapiens (human)
thymocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of thymocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
necroptotic processCellular tumor antigen p53Homo sapiens (human)
cellular response to hypoxiaCellular tumor antigen p53Homo sapiens (human)
cellular response to xenobiotic stimulusCellular tumor antigen p53Homo sapiens (human)
cellular response to ionizing radiationCellular tumor antigen p53Homo sapiens (human)
cellular response to gamma radiationCellular tumor antigen p53Homo sapiens (human)
cellular response to UV-CCellular tumor antigen p53Homo sapiens (human)
stem cell proliferationCellular tumor antigen p53Homo sapiens (human)
signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
cellular response to actinomycin DCellular tumor antigen p53Homo sapiens (human)
positive regulation of release of cytochrome c from mitochondriaCellular tumor antigen p53Homo sapiens (human)
cellular senescenceCellular tumor antigen p53Homo sapiens (human)
replicative senescenceCellular tumor antigen p53Homo sapiens (human)
oxidative stress-induced premature senescenceCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathwayCellular tumor antigen p53Homo sapiens (human)
oligodendrocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of execution phase of apoptosisCellular tumor antigen p53Homo sapiens (human)
negative regulation of mitophagyCellular tumor antigen p53Homo sapiens (human)
regulation of mitochondrial membrane permeability involved in apoptotic processCellular tumor antigen p53Homo sapiens (human)
regulation of intrinsic apoptotic signaling pathway by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of miRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
negative regulation of G1 to G0 transitionCellular tumor antigen p53Homo sapiens (human)
negative regulation of miRNA processingCellular tumor antigen p53Homo sapiens (human)
negative regulation of glucose catabolic process to lactate via pyruvateCellular tumor antigen p53Homo sapiens (human)
negative regulation of pentose-phosphate shuntCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to hypoxiaCellular tumor antigen p53Homo sapiens (human)
regulation of fibroblast apoptotic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of stem cell proliferationCellular tumor antigen p53Homo sapiens (human)
positive regulation of cellular senescenceCellular tumor antigen p53Homo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathwayCellular tumor antigen p53Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (34)

Processvia Protein(s)Taxonomy
transcription cis-regulatory region bindingCellular tumor antigen p53Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
cis-regulatory region sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
core promoter sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
TFIID-class transcription factor complex bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription repressor activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription activator activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
protease bindingCellular tumor antigen p53Homo sapiens (human)
p53 bindingCellular tumor antigen p53Homo sapiens (human)
DNA bindingCellular tumor antigen p53Homo sapiens (human)
chromatin bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription factor activityCellular tumor antigen p53Homo sapiens (human)
mRNA 3'-UTR bindingCellular tumor antigen p53Homo sapiens (human)
copper ion bindingCellular tumor antigen p53Homo sapiens (human)
protein bindingCellular tumor antigen p53Homo sapiens (human)
zinc ion bindingCellular tumor antigen p53Homo sapiens (human)
enzyme bindingCellular tumor antigen p53Homo sapiens (human)
receptor tyrosine kinase bindingCellular tumor antigen p53Homo sapiens (human)
ubiquitin protein ligase bindingCellular tumor antigen p53Homo sapiens (human)
histone deacetylase regulator activityCellular tumor antigen p53Homo sapiens (human)
ATP-dependent DNA/DNA annealing activityCellular tumor antigen p53Homo sapiens (human)
identical protein bindingCellular tumor antigen p53Homo sapiens (human)
histone deacetylase bindingCellular tumor antigen p53Homo sapiens (human)
protein heterodimerization activityCellular tumor antigen p53Homo sapiens (human)
protein-folding chaperone bindingCellular tumor antigen p53Homo sapiens (human)
protein phosphatase 2A bindingCellular tumor antigen p53Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor bindingCellular tumor antigen p53Homo sapiens (human)
14-3-3 protein bindingCellular tumor antigen p53Homo sapiens (human)
MDM2/MDM4 family protein bindingCellular tumor antigen p53Homo sapiens (human)
disordered domain specific bindingCellular tumor antigen p53Homo sapiens (human)
general transcription initiation factor bindingCellular tumor antigen p53Homo sapiens (human)
molecular function activator activityCellular tumor antigen p53Homo sapiens (human)
promoter-specific chromatin bindingCellular tumor antigen p53Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (20)

Processvia Protein(s)Taxonomy
nuclear bodyCellular tumor antigen p53Homo sapiens (human)
nucleusCellular tumor antigen p53Homo sapiens (human)
nucleoplasmCellular tumor antigen p53Homo sapiens (human)
replication forkCellular tumor antigen p53Homo sapiens (human)
nucleolusCellular tumor antigen p53Homo sapiens (human)
cytoplasmCellular tumor antigen p53Homo sapiens (human)
mitochondrionCellular tumor antigen p53Homo sapiens (human)
mitochondrial matrixCellular tumor antigen p53Homo sapiens (human)
endoplasmic reticulumCellular tumor antigen p53Homo sapiens (human)
centrosomeCellular tumor antigen p53Homo sapiens (human)
cytosolCellular tumor antigen p53Homo sapiens (human)
nuclear matrixCellular tumor antigen p53Homo sapiens (human)
PML bodyCellular tumor antigen p53Homo sapiens (human)
transcription repressor complexCellular tumor antigen p53Homo sapiens (human)
site of double-strand breakCellular tumor antigen p53Homo sapiens (human)
germ cell nucleusCellular tumor antigen p53Homo sapiens (human)
chromatinCellular tumor antigen p53Homo sapiens (human)
transcription regulator complexCellular tumor antigen p53Homo sapiens (human)
protein-containing complexCellular tumor antigen p53Homo sapiens (human)
plasma membraneGlutamate receptor 2Rattus norvegicus (Norway rat)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (41)

TimeframeStudies, This Drug (%)All Drugs %
pre-19908 (19.51)18.7374
1990's2 (4.88)18.2507
2000's14 (34.15)29.6817
2010's13 (31.71)24.3611
2020's4 (9.76)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (2.38%)5.53%
Reviews1 (2.38%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other40 (95.24%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
3,3'-diindolylmethane[no description available]medium10indolesantineoplastic agent;
P450 inhibitor
2-naphthol[no description available]medium411naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
menaquinone 6[no description available]medium130
farnesol[no description available]medium20farnesolplant metabolite
naphthoquinones[no description available]medium50
2-amino-3-carboxy-1,4-naphthoquinone[no description available]medium10
vitamin k 1[no description available]medium40phylloquinones;
vitamin K		cofactor;
human metabolite;
plant metabolite
aspartic acid[no description available]medium10aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
glutamic acid[no description available]medium10glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
quinone[no description available]medium101,4-benzoquinonescofactor;
human xenobiotic metabolite;
mouse metabolite
heme[no description available]medium10
demethylmenaquinone[no description available]medium302-demethylmenaquinone
selenic acid[no description available]medium10selenium oxoacid
tacrolimus[no description available]medium10macrolide lactambacterial metabolite;
immunosuppressive agent
shikimic acid[no description available]medium30alpha,beta-unsaturated monocarboxylic acid;
cyclohexenecarboxylic acid;
hydroxy monocarboxylic acid		Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
trimethyloxamine[no description available]medium10tertiary amine oxideEscherichia coli metabolite;
metabolite;
osmolyte
carbon tetrachloride[no description available]medium10chlorocarbon;
chloromethanes		hepatotoxic agent;
refrigerant
menatetrenone[no description available]medium10menaquinoneanti-inflammatory agent;
antioxidant;
bone density conservation agent;
human metabolite;
neuroprotective agent
chlorophyll a[no description available]medium10chlorophyll;
methyl ester		cofactor
chlorophyll[no description available]medium10
propionic acid[no description available]medium10saturated fatty acid;
short-chain fatty acid		antifungal drug
lactose[no description available]medium10lactose
hydroxide ion[no description available]medium10oxygen hydridemouse metabolite
2,5-dihydroxybenzyl alcohol[no description available]medium10aromatic primary alcohol;
phenols		antineoplastic agent;
antioxidant;
apoptosis inhibitor;
fungal metabolite
lactic acid[no description available]medium102-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
acetic acid[no description available]medium10monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent
2-succinylbenzoate[no description available]medium60dicarboxylic acid
1-naphthol[no description available]medium10naphtholgenotoxin;
human xenobiotic metabolite
vitamin k semiquinone radical[no description available]medium60
coenzyme a[no description available]medium10adenosine 3',5'-bisphosphatecoenzyme;
Escherichia coli metabolite;
mouse metabolite
pyruvic acid[no description available]medium102-oxo monocarboxylic acidcofactor;
fundamental metabolite
chromates[no description available]medium10chromium oxoanion;
divalent inorganic anion		oxidising agent
phytic acid[no description available]medium10inositol phosphate
s-adenosylmethionine[no description available]medium10organic cation;
sulfonium compound		coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
farnesyl pyrophosphate[no description available]medium10farnesyl diphosphateEscherichia coli metabolite;
mouse metabolite
sesquiterpenes[no description available]medium10
muramidase[no description available]medium10
fumarates[no description available]medium10butenedioate;
C4-dicarboxylate		human metabolite;
metabolite;
Saccharomyces cerevisiae metabolite
monoisopropanolamine[no description available]low00amino alcohol;
secondary alcohol		Escherichia coli metabolite
dihydro-3-coumaric acid[no description available]low00monocarboxylic acidEscherichia coli metabolite;
human xenobiotic metabolite
3-mercaptopyruvic acid[no description available]low002-oxo monocarboxylic acid;
thiol		antidote to cyanide poisoning;
Escherichia coli metabolite;
human metabolite;
mouse metabolite
4-aminobutyraldehyde[no description available]low00aminobutanal;
omega-aminoaldehyde		Escherichia coli metabolite;
mouse metabolite
aminolevulinic acid[no description available]low004-oxo monocarboxylic acid;
amino acid zwitterion;
delta-amino acid		antineoplastic agent;
dermatologic drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
5,6,7,8-tetrahydropteridine[no description available]low00pteridinescofactor;
Escherichia coli metabolite
acetaldehyde[no description available]low00aldehydecarcinogenic agent;
EC 3.5.1.4 (amidase) inhibitor;
electron acceptor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
mutagen;
oxidising agent;
Saccharomyces cerevisiae metabolite;
teratogenic agent
acetyl phosphate[no description available]low00acyl monophosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
adenine[no description available]low006-aminopurines;
purine nucleobase		Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
agmatine[no description available]low00guanidines;
primary amino compound		Escherichia coli metabolite;
mouse metabolite
allantoin[no description available]low00imidazolidine-2,4-dione;
ureas		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite;
vulnerary
aminoacetone[no description available]low00methyl ketone;
propanones		Escherichia coli metabolite;
mouse metabolite
arsenic acid[no description available]low00arsenic oxoacidEscherichia coli metabolite
betaine aldehyde[no description available]low00quaternary ammonium ionAspergillus metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite
butyraldehyde[no description available]low00butanalsbiomarker;
Escherichia coli metabolite;
mouse metabolite
cadaverine[no description available]low00alkane-alpha,omega-diamineDaphnia magna metabolite;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite
carbamic acid[no description available]low00carbon oxoacid;
one-carbon compound;
organonitrogen compound		Escherichia coli metabolite
carbamyl phosphate[no description available]low00acyl monophosphate;
one-carbon compound		Escherichia coli metabolite;
mouse metabolite
ureidosuccinic acid[no description available]low00aspartic acid derivative;
C4-dicarboxylic acid;
N-carbamoyl-amino acid		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
choline[no description available]low00cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
chlorine[no description available]low00halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
coproporphyrinogen iii[no description available]low00coproporphyrinogenEscherichia coli metabolite;
mouse metabolite
2-aminoacetaldehyde[no description available]low00amino aldehyde;
omega-aminoaldehyde		Escherichia coli metabolite
2,3-diaminopropionic acid[no description available]low00alanine derivative;
amino acid zwitterion;
beta-amino acid;
diamino acid;
non-proteinogenic alpha-amino acid		Escherichia coli metabolite
octanoic acid[no description available]low00medium-chain fatty acid;
straight-chain saturated fatty acid		antibacterial agent;
Escherichia coli metabolite;
human metabolite
hydrogen sulfide[no description available]low00gas molecular entity;
hydracid;
mononuclear parent hydride;
sulfur hydride		Escherichia coli metabolite;
genotoxin;
metabolite;
signalling molecule;
toxin;
vasodilator agent
oxaluric acid[no description available]low002-oxo monocarboxylic acid;
ureas		Escherichia coli metabolite
n(1)-acetylspermidine[no description available]low00acetylspermidineEscherichia coli metabolite;
metabolite
propionaldehyde[no description available]low00alpha-CH2-containing aldehyde;
propanals		Escherichia coli metabolite
phosphoglycolate[no description available]low00carboxyalkyl phosphateEscherichia coli metabolite;
mouse metabolite
hydrogen selenide[no description available]low00mononuclear parent hydride;
selenium hydride		Escherichia coli metabolite;
mouse metabolite
cytosine[no description available]low00aminopyrimidine;
pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
3,3-dimethylallyl pyrophosphate[no description available]low00prenol phosphateepitope;
Escherichia coli metabolite;
mouse metabolite;
phosphoantigen
dihydrouracil[no description available]low00pyrimidoneEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
diacetyl[no description available]low00alpha-diketoneEscherichia coli metabolite;
Saccharomyces cerevisiae metabolite
dihydroxyacetone phosphate[no description available]low00glycerone phosphates;
primary alpha-hydroxy ketone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
dihydroxyacetone[no description available]low00ketotriose;
primary alpha-hydroxy ketone		antifungal agent;
Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
5,6-dimethylbenzimidazole[no description available]low00dimethylbenzimidazoleEscherichia coli metabolite;
human metabolite
dimethyl sulfoxide[no description available]low00sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
ethanolamine[no description available]low00ethanolamines;
primary alcohol;
primary amine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
formaldehyde[no description available]low00aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
gamma-butyrobetaine[no description available]low00amino-acid betaineEscherichia coli metabolite;
human metabolite
glycerol[no description available]low00alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
glyoxylic acid[no description available]low002-oxo monocarboxylic acid;
aldehydic acid		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
hydrogen cyanide[no description available]low00hydracid;
one-carbon compound		Escherichia coli metabolite;
human metabolite;
poison
hydrogen carbonate[no description available]low00carbon oxoanioncofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
toxopyrimidine[no description available]low00aminopyrimidine;
aromatic primary alcohol		Escherichia coli metabolite;
Saccharomyces cerevisiae metabolite
thiocyanic acid[no description available]low00hydracid;
one-carbon compound;
organosulfur compound		Escherichia coli metabolite
hydroquinone[no description available]low00benzenediol;
hydroquinones		antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent
hydroxymethylbilane[no description available]low00bilanesEscherichia coli metabolite;
mouse metabolite
iminoaspartic acid[no description available]low00aspartic acid derivative;
C4-dicarboxylic acid;
ketimine		Escherichia coli metabolite
indole[no description available]low00indole;
polycyclic heteroarene		Escherichia coli metabolite
lipoamide[no description available]low00dithiolanes;
monocarboxylic acid amide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
racemethionine[no description available]low00alpha-amino acid;
amino acid zwitterion;
sulfur-containing amino acid		algal metabolite;
Daphnia magna metabolite;
Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
pyruvaldehyde[no description available]low002-oxo aldehyde;
propanals		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
methanol[no description available]low00alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
niacinamide[no description available]low00pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor
niacin[no description available]low00pyridine alkaloid;
pyridinemonocarboxylic acid;
vitamin B3		antidote;
antilipemic drug;
EC 3.5.1.19 (nicotinamidase) inhibitor;
Escherichia coli metabolite;
human urinary metabolite;
metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent
hydroxypyruvic acid[no description available]low002-oxo monocarboxylic acid;
3-hydroxy monocarboxylic acid;
primary alpha-hydroxy ketone		Escherichia coli metabolite;
human metabolite
orotic acid[no description available]low00pyrimidinemonocarboxylic acidEscherichia coli metabolite;
metabolite;
mouse metabolite
oxamic acid[no description available]low00dicarboxylic acid monoamideEscherichia coli metabolite
4-aminobenzoic acid[no description available]low00aminobenzoic acid;
aromatic amino-acid zwitterion		allergen;
Escherichia coli metabolite;
plant metabolite
phenylacetaldehyde[no description available]low00alpha-CH2-containing aldehyde;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
phenylacetic acid[no description available]low00benzenes;
monocarboxylic acid;
phenylacetic acids		allergen;
Aspergillus metabolite;
auxin;
EC 6.4.1.1 (pyruvate carboxylase) inhibitor;
Escherichia coli metabolite;
human metabolite;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite;
toxin
phenethylamine[no description available]low00alkaloid;
aralkylamine;
phenylethylamine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
porphobilinogen[no description available]low00aralkylamino compound;
dicarboxylic acid;
pyrroles		Escherichia coli metabolite;
metabolite;
mouse metabolite
diphosphoric acid[no description available]low00acyclic phosphorus acid anhydride;
phosphorus oxoacid		Escherichia coli metabolite
prephenic acid[no description available]low00oxo dicarboxylic acidEscherichia coli metabolite;
plant metabolite
pyridoxal[no description available]low00hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxal phosphate[no description available]low00methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate		coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxamine[no description available]low00aminoalkylpyridine;
hydroxymethylpyridine;
monohydroxypyridine;
vitamin B6		Escherichia coli metabolite;
human metabolite;
iron chelator;
mouse metabolite;
nephroprotective agent;
plant metabolite;
Saccharomyces cerevisiae metabolite
pyridoxamine phosphate[no description available]low00aminoalkylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6 phosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxine[no description available]low00hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyridoxine 5-phosphate[no description available]low00vitamin B6 phosphateEscherichia coli metabolite;
mouse metabolite
quinolinic acid[no description available]low00pyridinedicarboxylic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist
dimethyl sulfide[no description available]low00aliphatic sulfidealgal metabolite;
bacterial xenobiotic metabolite;
EC 3.5.1.4 (amidase) inhibitor;
Escherichia coli metabolite;
marine metabolite
sarcosine[no description available]low00N-alkylglycine zwitterion;
N-alkylglycine;
N-methyl-amino acid;
N-methylglycines		Escherichia coli metabolite;
glycine receptor agonist;
glycine transporter 1 inhibitor;
human metabolite;
mouse metabolite
succinic semialdehyde[no description available]low00aldehydic acidEscherichia coli metabolite;
mouse metabolite
sulfur dioxide[no description available]low00sulfur oxideEscherichia coli metabolite;
food bleaching agent;
refrigerant
tartronate semialdehyde[no description available]low002-hydroxy monocarboxylic acid;
3-oxo monocarboxylic acid;
aldehyde		Escherichia coli metabolite;
mouse metabolite
taurine[no description available]low00amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
thiamine[no description available]low00primary alcohol;
vitamin B1		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
thymine[no description available]low00pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite
2-(4-methyl-1,3-thiazol-5-yl)ethanol[no description available]low001,3-thiazoles;
primary alcohol		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
trimethylamine[no description available]low00methylamines;
tertiary amine		Escherichia coli metabolite;
human xenobiotic metabolite
uracil[no description available]low00pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
uric acid[no description available]low00uric acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
urea[no description available]low00isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
uroporphyrinogen iii[no description available]low00uroporphyrinogenEscherichia coli metabolite;
mouse metabolite
isopentenyl pyrophosphate[no description available]low00prenol phosphateantigen;
antioxidant;
epitope;
Escherichia coli metabolite;
mouse metabolite;
phosphoantigen
beta-glycerophosphoric acid[no description available]low00glycerol monophosphateEscherichia coli metabolite;
plant metabolite
4-cresol[no description available]low00cresolEscherichia coli metabolite;
human metabolite;
uremic toxin
4-aminobenzoic acid[no description available]low00aminobenzoate;
aromatic amino-acid anion		Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
tyramine[no description available]low00monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
sorbitol[no description available]low00glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
thymidine[no description available]low00pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
serine[no description available]low00L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
chloramphenicol[no description available]low00C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
glutamine[no description available]low00amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
lysine[no description available]low00aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
sucrose[no description available]low00glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
uridine monophosphate[no description available]low00pyrimidine ribonucleoside 5'-monophosphate;
uridine 5'-phosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
uridine diphosphate[no description available]low00pyrimidine ribonucleoside 5'-diphosphate;
uridine 5'-phosphate		Escherichia coli metabolite;
mouse metabolite
galactose[no description available]low00D-galactose;
galactopyranose		Escherichia coli metabolite;
mouse metabolite
leucine[no description available]low00amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
cytidine monophosphate[no description available]low00cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
cytidine diphosphate[no description available]low00cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-diphosphate		Escherichia coli metabolite;
mouse metabolite
uridine triphosphate[no description available]low00pyrimidine ribonucleoside 5'-triphosphate;
uridine 5'-phosphate		Escherichia coli metabolite;
mouse metabolite
phenylalanine[no description available]low00amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid		algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
cytidine[no description available]low00cytidinesEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
cytidine triphosphate[no description available]low00cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
mannitol[no description available]low00mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent
asparagine[no description available]low00amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
histidine[no description available]low00amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
valine[no description available]low00L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
threonine[no description available]low00amino acid zwitterion;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
threonine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
tryptophan[no description available]low00erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
isoleucine[no description available]low00aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
arginine[no description available]low00arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
methanesulfonic acid[no description available]low00alkanesulfonic acid;
one-carbon compound		Escherichia coli metabolite
phosphoribosyl pyrophosphate[no description available]low005-O-phosphono-D-ribofuranosyl diphosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite
trehalose[no description available]low00trehaloseEscherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
acetol[no description available]low00methyl ketone;
primary alcohol;
primary alpha-hydroxy ketone;
propanones		Escherichia coli metabolite;
human metabolite;
mouse metabolite
framycetin[no description available]low00aminoglycosideallergen;
antibacterial drug;
Escherichia coli metabolite
citrulline[no description available]low00amino acid zwitterion;
citrulline		Daphnia magna metabolite;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
protective agent;
Saccharomyces cerevisiae metabolite
phosphoadenosine phosphosulfate[no description available]low00acyl sulfate;
adenosine bisphosphate;
purine ribonucleoside bisphosphate		Escherichia coli metabolite;
mouse metabolite
adenosine phosphosulfate[no description available]low00acyl monophosphate;
acyl sulfate;
adenosine 5'-phosphate		Escherichia coli metabolite;
mouse metabolite
pyridoxamine dihydrochloride[no description available]low00hydrochloride;
vitamin B6		Escherichia coli metabolite;
human metabolite;
iron chelator;
mouse metabolite;
nephroprotective agent;
plant metabolite;
Saccharomyces cerevisiae metabolite
galactitol[no description available]low00hexitolEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
chorismic acid[no description available]low005-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acidEscherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
homoserine[no description available]low00amino acid zwitterion;
homoserine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
deoxycytidine[no description available]low00pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxyuridine[no description available]low00pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2'-deoxyadenosine[no description available]low00purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxycytidine monophosphate[no description available]low002'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
mouse metabolite
nicotinamide mononucleotide[no description available]low00nicotinamide mononucleotideEscherichia coli metabolite;
mouse metabolite
2'-deoxyadenosine triphosphate[no description available]low002'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
fucose[no description available]low00fucopyranose;
L-fucose		Escherichia coli metabolite;
mouse metabolite
uridine diphosphate glucuronic acid[no description available]low00UDP-D-glucuronic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
1,3,4-butanetriol[no description available]low00triolbacterial xenobiotic metabolite;
Escherichia coli metabolite
diadenosine tetraphosphate[no description available]low00diadenosyl tetraphosphateEscherichia coli metabolite;
mouse metabolite
d-glutamate[no description available]low00D-alpha-amino acid;
glutamic acid		Escherichia coli metabolite;
mouse metabolite
manganese[no description available]low00elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
silver[no description available]low00copper group element atom;
elemental silver		Escherichia coli metabolite
molybdate ion[no description available]low00divalent inorganic anion;
molybdenum oxoanion		Escherichia coli metabolite
myrmicacin[no description available]low003-hydroxy fatty acid;
medium-chain fatty acid		antimitotic;
Escherichia coli metabolite
phosphotyrosine[no description available]low00L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid;
O(4)-phosphotyrosine		Escherichia coli metabolite;
immunogen
adenosine diphosphate ribose[no description available]low00ADP-sugarEscherichia coli metabolite;
mouse metabolite
acetylgalactosamine[no description available]low00N-acetyl-D-hexosamine;
N-acetylgalactosamine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
phosphopantothenic acid[no description available]low00amidoalkyl phosphateEscherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
d-lactic acid[no description available]low002-hydroxypropanoic acidEscherichia coli metabolite;
human metabolite
xanthosine[no description available]low00purines D-ribonucleoside;
xanthosines		Escherichia coli metabolite;
human metabolite;
mouse metabolite
thymidine 5'-triphosphate[no description available]low00pyrimidine 2'-deoxyribonucleoside 5'-triphosphate;
thymidine phosphate		Escherichia coli metabolite;
mouse metabolite
2'-deoxyuridylic acid[no description available]low00deoxyuridine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
metabolite;
mouse metabolite
deoxyuridine triphosphate[no description available]low00deoxyuridine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-triphosphate		Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite
2'-deoxycytidine 5'-triphosphate[no description available]low002'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-triphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
aica ribonucleotide[no description available]low001-(phosphoribosyl)imidazolecarboxamide;
aminoimidazole		cardiovascular drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
glutathione disulfide[no description available]low00glutathione derivative;
organic disulfide		Escherichia coli metabolite;
mouse metabolite
n-(3-aminopropyl)cadaverine[no description available]low00polyazaalkane;
triamine		Escherichia coli metabolite
3'-cmp[no description available]low00cytidine 3'-phosphate;
pyrimidine ribonucleoside 3'-monophosphate		Escherichia coli metabolite;
metabolite;
mouse metabolite
hydracrylic acid[no description available]low003-hydroxy monocarboxylic acid;
omega-hydroxy-short-chain fatty acid		Escherichia coli metabolite;
human metabolite
plasmenylserine[no description available]low00O-phosphoserineEC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor;
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
cifostodine[no description available]low002',3'-cyclic pyrimidine nucleotideEscherichia coli metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
ubiquinone-o[no description available]low00ubiquinonesEscherichia coli metabolite;
human metabolite
D-serine[no description available]low00D-alpha-amino acid;
serine zwitterion;
serine		Escherichia coli metabolite;
human metabolite;
NMDA receptor agonist
D-alanine[no description available]low00alanine zwitterion;
alanine;
D-alpha-amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite
D-tyrosine[no description available]low00D-alpha-amino acid zwitterion;
D-alpha-amino acid;
tyrosine		Escherichia coli metabolite
xanthosine 5'-triphosphate[no description available]low00purine ribonucleoside 5'-monophosphate;
xanthosine 5'-phosphate		Escherichia coli metabolite;
metabolite;
mouse metabolite
glucose-1,6-bisphosphate[no description available]low00D-glucose 1,6-bisphosphateEscherichia coli metabolite;
human metabolite
succinyl-coenzyme a[no description available]low00omega-carboxyacyl-CoAEscherichia coli metabolite;
inhibitor;
mouse metabolite
L-2-aminoadipic acid[no description available]low002-aminoadipic acidEscherichia coli metabolite;
human metabolite
acetoacetyl coa[no description available]low003-oxo-fatty acyl-CoAEscherichia coli metabolite;
mouse metabolite
propionyl-coenzyme a[no description available]low00acyl-CoAEscherichia coli metabolite;
metabolite;
mouse metabolite
stearoyl-coenzyme a[no description available]low0011,12-saturated fatty acyl-CoA;
long-chain fatty acyl-CoA		Escherichia coli metabolite;
mouse metabolite
3'-uridylic acid[no description available]low00pyrimidine ribonucleoside 3'-monophosphate;
uridine phosphate		Escherichia coli metabolite
2',3'-cyclic amp[no description available]low002',3'-cyclic purine nucleotideEscherichia coli metabolite
2,5-diketogluconic acid[no description available]low00diketoaldonic acidEscherichia coli metabolite
l-lactic acid[no description available]low00(2S)-2-hydroxy monocarboxylic acid;
2-hydroxypropanoic acid		Escherichia coli metabolite;
human metabolite
selenodiglutathione[no description available]low00glutathione derivative;
thioselenide		Escherichia coli metabolite;
metabolite
2-deoxyglucose-6-phosphate[no description available]low00deoxyaldohexose phosphateEscherichia coli metabolite;
Mycoplasma genitalium metabolite
3,4-dihydroxyphenylacetaldehyde[no description available]low00alpha-CH2-containing aldehyde;
catechols;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite
protoporphyrinogen[no description available]low00porphyrinogensEscherichia coli metabolite;
mouse metabolite
thymidine diphosphate-l-rhamnose[no description available]low00dTDP-L-rhamnoseEscherichia coli metabolite
butyryl-coenzyme a[no description available]low00butanoyl-CoAsEscherichia coli metabolite;
mouse metabolite
trehalose-6-phosphate[no description available]low00trehalose phosphateEscherichia coli metabolite
erythrose 4-phosphate[no description available]low00erythrose phosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
ribulose-1,5 diphosphate[no description available]low00ribulose phosphateEscherichia coli metabolite;
plant metabolite
n(8)-acetylspermidine[no description available]low00acetylspermidineEscherichia coli metabolite;
human metabolite
aerobactin[no description available]low00L-lysine derivativeEscherichia coli metabolite;
siderophore;
virulence factor
lipid x[no description available]low00N-acyl-D-glucosamine 1-phosphateEscherichia coli metabolite
galactose-1-phosphate[no description available]low00alpha-D-hexose 1-phosphate;
D-galactopyranose 1-phosphate		Escherichia coli metabolite;
mouse metabolite
gamma-glutamylcysteine[no description available]low00gamma-glutamylcysteineEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
glutamate-1-semialdehyde[no description available]low005-oxo monocarboxylic acid;
amino acid zwitterion;
gamma-amino acid;
glutamic semialdehyde		Escherichia coli metabolite
mannitol-1-phosphate[no description available]low00alditol 1-phosphate;
hexitol phosphate		Escherichia coli metabolite;
human metabolite
proline[no description available]low00amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
2'-deoxycytidine diphosphate[no description available]low002'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-diphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
o-phosphohomoserine[no description available]low00O-phosphorylhomoserineEscherichia coli metabolite
ribulose[no description available]low00ribuloseEscherichia coli metabolite;
human metabolite
2,3-dihydroxybenzoylserine[no description available]low00L-serine derivativeEscherichia coli metabolite
sorbitol 6-phosphate[no description available]low00alditol 6-phosphate;
glucitol phosphate		Escherichia coli metabolite;
mouse metabolite
beta-aspartyl phosphate[no description available]low00aminoacyl phosphate;
L-aspartic acid derivative;
non-proteinogenic L-alpha-amino acid		Escherichia coli metabolite
adenosine 3'-phosphate-5'-phosphate[no description available]low00adenosine bisphosphateEscherichia coli metabolite;
mouse metabolite
alpha-ribazole[no description available]low001-ribosylbenzimidazole;
dimethylbenzimidazole		Escherichia coli metabolite;
mouse metabolite
abrine[no description available]low00L-tryptophan derivative;
N-methyl-L-alpha-amino acid zwitterion;
N-methyl-L-alpha-amino acid		Escherichia coli metabolite
orotidylic acid[no description available]low00pyrimidine ribonucleoside 5'-monophosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
3-deoxy-d-arabino-heptulosonate-7-phosphate[no description available]low00ketoaldonic acid phosphateEscherichia coli metabolite
saicar[no description available]low001-(phosphoribosyl)imidazolecarboxamideEscherichia coli metabolite;
mouse metabolite
n(6)-(n-threonylcarbonyl)adenosine[no description available]low00L-threonine derivative;
N-(adenosin-N(6)-ylcarbonyl)threonine		Escherichia coli metabolite;
human metabolite
thymidine 5'-diphosphate[no description available]low00pyrimidine 2'-deoxyribonucleoside 5'-diphosphate;
thymidine phosphate		Escherichia coli metabolite;
mouse metabolite
sedoheptulose 1,7-bisphosphate[no description available]low00ketoheptose phosphate;
sedoheptulose derivative		Escherichia coli metabolite;
mouse metabolite
sedoheptulose 7-phosphate[no description available]low00ketoheptose phosphate;
sedoheptulose derivative		Escherichia coli metabolite;
human metabolite;
mouse metabolite
histidinol[no description available]low00amino alcohol;
imidazoles		EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor;
Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
carboxyaminoimidazole ribotide[no description available]low001-(phosphoribosyl)imidazole;
aminoimidazole;
imidazole-4-carboxylic acid		Escherichia coli metabolite;
mouse metabolite
lauroyl-coenzyme a[no description available]low00medium-chain fatty acyl-CoAEscherichia coli metabolite;
mouse metabolite
nicotinic acid adenine dinucleotide[no description available]low00nicotinic acid dinucleotideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
phenylacetyl-coenzyme a[no description available]low00acyl-CoAEscherichia coli metabolite;
metabolite;
mouse metabolite
5-formamidoimidazole-4-carboxamide ribotide[no description available]low001-(phosphoribosyl)imidazolecarboxamideEscherichia coli metabolite;
mouse metabolite
6,7-dimethyl-8-ribityllumazine, (d)-isomer[no description available]low00pteridinescofactor;
Escherichia coli metabolite
biotin[no description available]low00biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
glucosamine 1-phosphate[no description available]low00glucosamine phosphateEscherichia coli metabolite
2'-deoxyadenosine triphosphate[no description available]low002'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-diphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
9-mercaptodethiobiotin[no description available]low00imidazolidinone;
monocarboxylic acid;
thiol;
ureas		Escherichia coli metabolite
idonic acid[no description available]low00idonic acidEscherichia coli metabolite
gamma-glutamyl phosphate[no description available]low00gamma-glutamyl phosphateEscherichia coli metabolite;
mouse metabolite
5-amino-6-ribitylamino-2,4-(1h,3h)pyrimidinedione[no description available]low00aminouracil;
hydroxypyrimidine		Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
hydroxythreonine[no description available]low00amino acid zwitterion;
hydroxy-amino acid;
L-threonine derivative;
non-proteinogenic L-alpha-amino acid		Escherichia coli metabolite;
Saccharomyces cerevisiae metabolite
n(1)-((5'-phosphoribulosyl)formimino)-5-aminoimidazo-4-carboxamide ribonucleotide[no description available]low001-(phosphoribosyl)imidazolecarboxamideEscherichia coli metabolite
2-oxo-3-deoxygalactonic acid[no description available]low00hexonic acid;
ketoaldonic acid		Escherichia coli metabolite
5'-methylthioadenosine[no description available]low00thioadenosinealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
5'-deoxyadenosine[no description available]low005'-deoxyribonucleoside;
adenosines		Escherichia coli metabolite;
human metabolite;
mouse metabolite
xylulose-5-phosphate, (d)-isomer[no description available]low00xylulose 5-phosphateEscherichia coli metabolite;
mouse metabolite
glycerate 1,3-biphosphate[no description available]low002,3-bisphosphoglyceric acid;
acyl monophosphate		Escherichia coli metabolite;
mouse metabolite
arabinose[no description available]low00L-arabinoseEscherichia coli metabolite;
mouse metabolite
glucosamine[no description available]low00D-glucosamineEscherichia coli metabolite;
geroprotector;
mouse metabolite
ribose 1-phosphate[no description available]low00D-ribose 1-phosphateEscherichia coli metabolite
diaminopimelic acid[no description available]low002,6-diaminopimelic acid;
amino acid zwitterion		Escherichia coli metabolite
xanthosine 5'-triphosphate[no description available]low00purine ribonucleoside 5'-triphosphate;
xanthosine 5'-phosphate		Escherichia coli metabolite;
mouse metabolite
3-dehydroquinic acid[no description available]low002-hydroxy monocarboxylic acid;
4-hydroxy monocarboxylic acid;
4-oxo monocarboxylic acid;
5-hydroxy monocarboxylic acid;
secondary alpha-hydroxy ketone		Escherichia coli metabolite
o-succinylhomoserine[no description available]low00hemisuccinate;
o-succinylhomoserine		Escherichia coli metabolite;
Saccharomyces cerevisiae metabolite
s-adenosyl-3-methylthiopropylamine[no description available]low00adenosines;
sulfonium compound		Escherichia coli metabolite;
human urinary metabolite;
mouse metabolite;
rat metabolite
6-phosphonoglucono-delta-lactone[no description available]low00aldonolactone phosphateEscherichia coli metabolite;
mouse metabolite
cysteinylglycine[no description available]low00dipeptide zwitterion;
dipeptide		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
tartaric acid[no description available]low00tartaric acidEscherichia coli metabolite
s-ribosyl-l-homocysteine[no description available]low00S-(5-deoxy-D-ribos-5-yl)-L-homocysteineEscherichia coli metabolite
4-hydroxyphenylacetaldehyde[no description available]low00alpha-CH2-containing aldehyde;
phenylacetaldehydes		Escherichia coli metabolite;
human metabolite;
mouse metabolite
nitro-bis(2,4-pentanedionato)(pyridine)cobalt(iii)[no description available]low00diadenosyl pentaphosphateEscherichia coli metabolite;
vasoconstrictor agent
n-acetylglucosamine-1-phosphate[no description available]low00N-acetyl-D-glucosamine 1-phosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
pantothenylcysteine 4'-phosphate[no description available]low00L-cysteine derivativeEscherichia coli metabolite;
mouse metabolite
glutathionylspermidine[no description available]low00glutathione derivativeEscherichia coli metabolite
arbutin[no description available]low00beta-D-glucoside;
monosaccharide derivative		Escherichia coli metabolite;
plant metabolite
2-c-methylerythritol 4-phosphate[no description available]low00tetritol phosphateEscherichia coli metabolite
1-deoxy-d-xylulose 5-phosphate[no description available]low00xylulose phosphateEscherichia coli metabolite
c(alpha)-formylglycine[no description available]low003-oxoalanine;
amino acid zwitterion;
L-alanine derivative;
non-proteinogenic L-alpha-amino acid		Escherichia coli metabolite
dephosphocoenzyme a[no description available]low00adenosine 5'-phosphateEscherichia coli metabolite;
human metabolite;
mouse metabolite
n(1)-(5-phosphoribosyl)-5,6-dimethylbenzimidazole[no description available]low001-ribosylbenzimidazole;
dimethylbenzimidazole;
ribose monophosphate		Escherichia coli metabolite;
mouse metabolite
ribothymidine[no description available]low00methyluridineantigen;
Escherichia coli metabolite;
human metabolite
palmitoleic acid[no description available]low00hexadec-9-enoic acidalgal metabolite;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
human blood serum metabolite
oleic acid[no description available]low00octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent
geranyl pyrophosphate[no description available]low00polyprenyl diphosphateEscherichia coli metabolite;
mouse metabolite
1,5-dihydro-fad[no description available]low00flavin adenine dinucleotideEscherichia coli metabolite;
mouse metabolite
s-hydroxymethylglutathione[no description available]low00S-substituted glutathioneEscherichia coli metabolite;
mouse metabolite
hexanoyl-coenzyme a[no description available]low00medium-chain fatty acyl-CoAEscherichia coli metabolite;
human metabolite;
mouse metabolite
4-phosphoerythronate[no description available]low004-phosphoerythronic acidEscherichia coli metabolite;
mouse metabolite
riboflavin[no description available]low00flavin;
vitamin B2		anti-inflammatory agent;
antioxidant;
cofactor;
Escherichia coli metabolite;
food colouring;
fundamental metabolite;
human urinary metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite
flavin-adenine dinucleotide[no description available]low00flavin adenine dinucleotide;
vitamin B2		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prosthetic group
malonyl coenzyme a[no description available]low00malonyl-CoAsEC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor;
Escherichia coli metabolite;
metabolite;
mouse metabolite
sucrose-6-phosphate[no description available]low00disaccharide phosphateEscherichia coli metabolite
palmitoyl coenzyme a[no description available]low0011,12-saturated fatty acyl-CoA;
3-substituted propionyl-CoA;
long-chain fatty acyl-CoA;
palmitoyl bioconjugate		Escherichia coli metabolite;
mouse metabolite
glycerylphosphorylcholine[no description available]low00phosphocholines;
sn-glycerol 3-phosphates		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neuroprotective agent;
parasympatholytic;
Saccharomyces cerevisiae metabolite
cysteine sulfinic acid[no description available]low00organosulfinic acid;
S-substituted L-cysteine		Escherichia coli metabolite;
human metabolite;
metabotropic glutamate receptor agonist;
mouse metabolite
fusidic acid[no description available]low0011alpha-hydroxy steroid;
3alpha-hydroxy steroid;
alpha,beta-unsaturated monocarboxylic acid;
steroid acid;
steroid antibiotic;
sterol ester		EC 2.7.1.33 (pantothenate kinase) inhibitor;
Escherichia coli metabolite;
protein synthesis inhibitor
iminoglycine[no description available]low00dehydroamino acid;
imine;
zwitterion		Escherichia coli metabolite
2-keto-3-deoxy-6-phosphogluconate[no description available]low00ketoaldonic acid phosphateEscherichia coli metabolite
formyl-coenzyme a[no description available]low00acyl-CoAEscherichia coli metabolite
3-deoxy-2-octulosonic acid(2)-lipid iv(a)[no description available]low00lipid AsEscherichia coli metabolite
phosphothreonine[no description available]low00L-threonine derivative;
non-proteinogenic L-alpha-amino acid;
O-phosphoamino acid		Escherichia coli metabolite
maleamic acid[no description available]low00alpha,beta-unsaturated monocarboxylic acid;
dicarboxylic acid monoamide		bacterial xenobiotic metabolite;
Escherichia coli metabolite
retinol palmitate[no description available]low00all-trans-retinyl ester;
retinyl palmitate		antioxidant;
Escherichia coli metabolite;
human xenobiotic metabolite
canthaxanthin[no description available]low00carotenonebiological pigment;
Escherichia coli metabolite;
food colouring;
fungal metabolite
(e)-4-hydroxy-3-methylbut-2-enyl diphosphate[no description available]low00prenol phosphateepitope;
Escherichia coli metabolite;
phosphoantigen
menaquinone 7[no description available]low00menaquinonebone density conservation agent;
cofactor;
Escherichia coli metabolite;
human blood serum metabolite;
Mycoplasma genitalium metabolite
xylulose[no description available]low00xyluloseEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
vitamin mk 8[no description available]low00menaquinoneEscherichia coli metabolite;
human metabolite
5-ketogluconic acid[no description available]low00hexonic acid;
ketoaldonic acid		Escherichia coli metabolite
oleoyl-coenzyme a[no description available]low00octadecenoyl-CoAEscherichia coli metabolite;
mouse metabolite
menaquinone 9[no description available]low00menaquinoneEscherichia coli metabolite
allolactose[no description available]low00glycosylglucoseEscherichia coli metabolite
fuculose[no description available]low00deoxyketohexoseEscherichia coli metabolite;
human metabolite
1-deoxy-2-pentulose[no description available]low00deoxypentoseEscherichia coli metabolite
fructosyl-lysine[no description available]low00fructosamine;
glyco-amino acid		Escherichia coli metabolite
lipid a[no description available]low00dodecanoate ester;
lipid A;
tetradecanoate ester		Escherichia coli metabolite
methionine sulfoxide[no description available]low00amino acid zwitterion;
L-methionine S-oxide		Escherichia coli metabolite
(S)-4,5-dihydroxypentane-2,3-dione[no description available]low00alpha-diketone;
secondary alpha-hydroxy ketone		Escherichia coli metabolite
kdo2-lipid a[no description available]low00dodecanoate ester;
lipid As;
tetradecanoate ester		Escherichia coli metabolite
oxalyl-coenzyme a[no description available]low00omega-carboxyacyl-CoAEscherichia coli metabolite
s-tetradecanoyl-coenzyme a[no description available]low0011,12-saturated fatty acyl-CoA;
long-chain fatty acyl-CoA		Escherichia coli metabolite;
mouse metabolite
novobiocin[no description available]low00carbamate ester;
ether;
hexoside;
hydroxycoumarin;
monocarboxylic acid amide;
monosaccharide derivative;
phenols		antibacterial agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Escherichia coli metabolite;
hepatoprotective agent
cyclic gmp[no description available]low003',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
diguanosine tetraphosphate[no description available]low00guanosine 5'-phosphate;
purine ribonucleoside 5'-tetraphosphate		Escherichia coli metabolite;
mouse metabolite
deoxyguanosine[no description available]low00purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxyinosine[no description available]low00purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
2'-deoxyguanosine 5'-phosphate[no description available]low00deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
mouse metabolite
deoxyguanosine triphosphate[no description available]low00deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-triphosphate		Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
7,8-dihydroneopterin[no description available]low00dihydropterin;
neopterins		Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
dihydrofolate[no description available]low00dihydrofolic acidsEscherichia coli metabolite;
mouse metabolite
dihydroneopterin triphosphate[no description available]low00dihydropterin;
neopterins;
pterin phosphate		Escherichia coli metabolite;
mouse metabolite
deoxyinosine monophosphate[no description available]low00deoxyinosine phosphate;
purine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
2'-deoxyinosine triphosphate[no description available]low00deoxyinosine phosphate;
purine 2'-deoxyribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
guanosine diphosphate[no description available]low00guanosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
gdp-4-keto-6-deoxymannose[no description available]low00GDP-sugarEscherichia coli metabolite;
mouse metabolite
guanosine diphosphate mannose[no description available]low00GDP-D-mannoseEscherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite
guanosine pentaphosphate[no description available]low00guanosine 5'-phosphate;
guanosine bisphosphate		Escherichia coli metabolite;
mouse metabolite
guanosine monophosphate[no description available]low00guanosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		biomarker;
Escherichia coli metabolite;
metabolite;
mouse metabolite
guanosine triphosphate[no description available]low00guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
guanine[no description available]low002-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
guanosine tetraphosphate[no description available]low00guanosine bisphosphateEscherichia coli metabolite;
mouse metabolite
inosinic acid[no description available]low00inosine phosphate;
purine ribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
inosine[no description available]low00inosines;
purines D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
inosine triphosphate[no description available]low00inosine phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
queuine[no description available]low00pyrrolopyrimidineEscherichia coli metabolite
3'-guanylic acid[no description available]low00guanosine 3'-phosphate;
purine ribonucleoside 3'-monophosphate		Escherichia coli metabolite
2',3'-cyclic gmp[no description available]low002',3'-cyclic purine nucleotideEscherichia coli metabolite
rifampin[no description available]low00cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
leucovorin[no description available]low00formyltetrahydrofolic acidEscherichia coli metabolite;
mouse metabolite
5,10-methenyltetrahydrofolate[no description available]low00methylenetetrahydrofolic acidEscherichia coli metabolite;
mouse metabolite
10-formyltetrahydrofolate[no description available]low00formyltetrahydrofolic acidEscherichia coli metabolite;
mouse metabolite
colibactin[no description available]low001,3-thiazoles;
azaspiro compound;
polyketide;
pyrroline;
secondary carboxamide		alkylating agent;
carcinogenic agent;
Escherichia coli metabolite;
genotoxin
alpha,beta-dihydroxyisovaleric acid[no description available]low00dihydroxy monocarboxylic acid
atorvastatin[no description available]low00aromatic amide;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
pyrroles;
statin (synthetic)		environmental contaminant;
xenobiotic
l 154819[no description available]low00carbobicyclic compound;
dihydroxy monocarboxylic acid;
fatty acid ester;
polyketide		Aspergillus metabolite;
drug metabolite;
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
teratogenic agent
hederagenin[no description available]low00dihydroxy monocarboxylic acid;
pentacyclic triterpenoid;
sapogenin		plant metabolite
maslinic acid[no description available]low00dihydroxy monocarboxylic acid;
pentacyclic triterpenoid		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
plant metabolite
9,10-dihydroxystearic acid[no description available]low00dihydroxy monocarboxylic acid;
hydroxyoctadecanoic acid
3-(3-hydroxyphenyl)-3-hydroxypropanoic acid[no description available]low00dihydroxy monocarboxylic acid;
phenols		human urinary metabolite
cerivastatin[no description available]low00dihydroxy monocarboxylic acid;
pyridines;
statin (synthetic)
rosuvastatin[no description available]low00dihydroxy monocarboxylic acid;
monofluorobenzenes;
pyrimidines;
statin (synthetic);
sulfonamide		anti-inflammatory agent;
antilipemic drug;
cardioprotective agent;
CETP inhibitor;
environmental contaminant;
xenobiotic
leukotriene b4[no description available]low00dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid		human metabolite;
mouse metabolite;
plant metabolite;
vasoconstrictor agent
pitavastatin[no description available]low00cyclopropanes;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
quinolines;
statin (synthetic)		antioxidant
leukotriene b5[no description available]low00dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid		anti-inflammatory agent;
human xenobiotic metabolite;
rat metabolite
(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid[no description available]low00dihydroxy monocarboxylic acid;
indoles;
organofluorine compound
5,12-dihydroxy-6,8,14-eicosatrienoic acid[no description available]low00dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid		human urinary metabolite;
human xenobiotic metabolite
atractyligenine[no description available]low00carbotetracyclic compound;
dihydroxy monocarboxylic acid;
ent-kaurane diterpenoid;
tetracyclic diterpenoid		plant metabolite
2alpha,3beta-dihydroxy-20(29)-lupen-28-oic acid[no description available]low00dihydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite
23-hydroxyursolic acid[no description available]low00dihydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite
epi-maslinic acid[no description available]low00dihydroxy monocarboxylic acid;
pentacyclic triterpenoid		anti-inflammatory agent;
metabolite
1-hydroxy-2-naphthoic acid[no description available]low00hydroxy monocarboxylic acid;
naphthoic acid;
naphthols		bacterial xenobiotic metabolite;
fungal xenobiotic metabolite
1-naphthoic acid[no description available]low00naphthoic acidbacterial xenobiotic metabolite;
fungal xenobiotic metabolite
3-hydroxy-2-naphthoic acid[no description available]low00naphthoic acid
2-naphthoic acid[no description available]low00naphthoic acidmouse metabolite;
xenobiotic metabolite
salmeterol xinafoate[no description available]low00naphthoic acid
adapalene[no description available]low00adamantanes;
monocarboxylic acid;
naphthoic acid		dermatologic drug;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
non-steroidal anti-inflammatory drug
cd 437[no description available]low00adamantanes;
monocarboxylic acid;
naphthoic acid;
phenols		apoptosis inducer;
retinoic acid receptor gamma agonist
6-Methoxy-2-naphthoic acid[no description available]low00naphthoic acid
3-methoxy-4-(2-methoxy-3-methoxycarbonyl-1-naphthalenyl)-2-naphthalenecarboxylic acid methyl ester[no description available]low00naphthoic acid
3-hydroxy-2-naphthalenecarboxylic acid [2-(4-methyl-1-piperidinyl)-2-oxoethyl] ester[no description available]low00naphthoic acid
3-methoxy-2-naphthalenecarboxylic acid [2-(4-morpholinyl)-2-oxoethyl] ester[no description available]low00naphthoic acid
3-hydroxy-2-naphthalenecarboxylic acid [2-(3,5-dimethyl-1-piperidinyl)-2-oxoethyl] ester[no description available]low00naphthoic acid
sto 609[no description available]low00naphthoic acid
oxantel pamoate[no description available]low00naphthoic acid
2-naphthalenecarboxylic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester[no description available]low00naphthoic acid
pyrvinium pamoate[no description available]low00naphthoic acidanticoronaviral agent
1,2-dihydroxy-1,2-dihydronaphthalene[no description available]low00dihydronaphthalenes;
naphthalenediols		bacterial xenobiotic metabolite;
mouse metabolite
menadiol[no description available]low00methylnaphthalenes;
naphthalenediols;
naphthohydroquinone
chromotropic acid[no description available]low00naphthalenediols;
naphthalenesulfonic acid		indicator
1,4-naphthohydroquinone[no description available]low00naphthalenediol;
naphthohydroquinone
vitamin k1 hydroquinone[no description available]low00naphthohydroquinone;
polyprenylhydroquinone
ConditionIndicatedRelationship StrengthStudiesTrials
Age-Related Osteoporosis0low10
Anhedonia0low10
Body Weight0low10
Bone Loss, Age-Related0low10
Colitis0low20
Disease Models, Animal0low30
Infections, Listeria0low10
Listeria Infections0low10
Listeriosis0low10
Osteoporosis0low10
Osteoporosis, Age-Related0low10
Osteoporosis, Involutional0low10
Osteoporosis, Post-Traumatic0low10
Osteoporosis, Senile0low10
Physical Anhedonia0low10
Senile Osteoporosis0low10
Social Anhedonia0low10

Research Highlights

Safety/Toxicity (1)

ArticleYear
Safety of high doses of Propionibacterium freudenreichii ET-3 culture in healthy adult subjects.
Regulatory toxicology and pharmacology : RTP, Volume: 60, Issue: 2		2011
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]