6-methyl-1-2-3-5-tetrahydroimidazo(2-1-b)quinazolin-2-one-hydrochloride and Osteoporosis

6-methyl-1-2-3-5-tetrahydroimidazo(2-1-b)quinazolin-2-one-hydrochloride has been researched along with Osteoporosis* in 1 studies

Other Studies

1 other study(ies) available for 6-methyl-1-2-3-5-tetrahydroimidazo(2-1-b)quinazolin-2-one-hydrochloride and Osteoporosis

Article	Year
Studies on osteoporoses. XII. Effect of imidazoquinazolinones on experimental osteoporosis. A preliminary report. Journal of medicine, 1982, Volume: 13, Issue:5-6 In vivo neutron activation analysis was employed to determine total body calcium content in C3H/St(Ha) female mice. Ninety-nine percent of calcium is in bone and loss of calcium was used as an index of osteoporosis. Heparin (500 U/kg b.i.d.) treatment for three months resulted in significant osteoporosis. BL3459 and BL4160 (6 mg/kg i.m. q.d.) prevented this heparin induced osteoporosis. BL4160 appeared to be more effective than BL3459 in this regard but the difference was not statistically significant. Topics: Animals; Calcium; Female; Heparin; Mice; Mice, Inbred C3H; Neutron Activation Analysis; Osteoporosis; Quinazolines	1982

Article

Year

Studies on osteoporoses. XII. Effect of imidazoquinazolinones on experimental osteoporosis. A preliminary report.

Journal of medicine, 1982, Volume: 13, Issue:5-6

In vivo neutron activation analysis was employed to determine total body calcium content in C3H/St(Ha) female mice. Ninety-nine percent of calcium is in bone and loss of calcium was used as an index of osteoporosis. Heparin (500 U/kg b.i.d.) treatment for three months resulted in significant osteoporosis. BL3459 and BL4160 (6 mg/kg i.m. q.d.) prevented this heparin induced osteoporosis. BL4160 appeared to be more effective than BL3459 in this regard but the difference was not statistically significant.

Topics: Animals; Calcium; Female; Heparin; Mice; Mice, Inbred C3H; Neutron Activation Analysis; Osteoporosis; Quinazolines

1982