Page last updated: 2024-10-17

creatine and Osteoporosis

creatine has been researched along with Osteoporosis in 19 studies

Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.

Research Excerpts

ExcerptRelevanceReference
"Sarcopenia is associated with other age-related conditions such as osteoporosis, frailty and cachexia."6.82Creatine supplementation for older adults: Focus on sarcopenia, osteoporosis, frailty and Cachexia. ( Candow, DG; Chilibeck, PD; Fairman, CM; Forbes, SC; Gualano, B; Roschel, H, 2022)
"Hyperhomocysteinemia may contribute to the development of osteoporosis."3.73Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people. ( de Groot, LC; Dhonukshe-Rutten, RA; Lips, P; Pluijm, SM; Smit, JH; van Staveren, WA, 2005)
"Two hundred postmenopausal women with osteopenia were randomly allocated to receive either creatine monohydrate (3 g/d) or placebo for 2 years."2.94Creatine Supplementation (3 g/d) and Bone Health in Older Women: A 2-Year, Randomized, Placebo-Controlled Trial. ( Alvarenga, JC; Benatti, FB; Gonçalves, N; Gualano, B; Pinto, AJ; Rodrigues Pereira, RM; Rodrigues, SF; Sales, LP; Sampaio-Barros, MM, 2020)
"Sarcopenia is associated with other age-related conditions such as osteoporosis, frailty and cachexia."2.82Creatine supplementation for older adults: Focus on sarcopenia, osteoporosis, frailty and Cachexia. ( Candow, DG; Chilibeck, PD; Fairman, CM; Forbes, SC; Gualano, B; Roschel, H, 2022)
"Osteoporosis in beta-thalassemia major has emerged as a topic of interest since optimized transfusion regimens have increased life expectancy and quality in these patients."2.71Quantitative ultrasound of bone and clodronate effects in thalassemia-induced osteoporosis. ( Fiore, CE; Pennisi, P; Pizzarelli, G; Riccobene, S; Spina, M, 2003)
" It is likely that a higher dosage would be more effective, but would cause the potential endometrial effects."2.65Bone loss during oestriol therapy in postmenopausal women. ( Clark, AC; Garwood, J; Hart, DM; Kraszewski, A; Lindsay, R; Maclean, A, 1979)
"Furthermore, congestive heart failure is associated with impaired creatinine clearance and increased urea and urate, and osteoporosis and hip fractures are characterized by low albumin and cholesterol."1.32Association of biochemical values with morbidity in the elderly: a population-based Swedish study of persons aged 82 or more years. ( Berg, S; Evrin, PE; Johansson, B; McClearn, G; Nilsson, SE; Takkinen, S; Tryding, N, 2003)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19907 (36.84)18.7374
1990's1 (5.26)18.2507
2000's5 (26.32)29.6817
2010's3 (15.79)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Candow, DG3
Chilibeck, PD2
Forbes, SC3
Fairman, CM1
Gualano, B3
Roschel, H2
Kirk, B1
Duque, G1
Sales, LP1
Pinto, AJ1
Rodrigues, SF1
Alvarenga, JC1
Gonçalves, N1
Sampaio-Barros, MM1
Benatti, FB1
Rodrigues Pereira, RM1
Murai, IH1
Pabis, LV1
Takayama, L1
de Oliveira, RB1
Dos Santos Pereira, RT1
Dantas, WS1
Pereira, RM1
Jorgetti, V1
Ballester, RY1
de Souza, RA1
Xavier, M1
da Silva, FF1
de Souza, MT1
Tosato, MG1
Martin, AA1
Castilho, JC1
Ribeiro, W1
Silveira, L1
CLARK, CG1
HAHNEMANN, S1
FRIIS, T1
HIGGINS, BA1
NASSIM, JR1
COLLINS, J1
HILB, A1
Pennisi, P1
Pizzarelli, G1
Spina, M1
Riccobene, S1
Fiore, CE1
Nilsson, SE1
Takkinen, S1
Tryding, N1
Evrin, PE1
Berg, S1
McClearn, G1
Johansson, B1
Seminari, E1
Castagna, A1
Soldarini, A1
Galli, L1
Fusetti, G1
Dorigatti, F1
Hasson, H1
Danise, A1
Guffanti, M1
Lazzarin, A1
Rubinacci, A1
Dhonukshe-Rutten, RA1
Pluijm, SM1
de Groot, LC1
Lips, P1
Smit, JH1
van Staveren, WA1
Sahota, O1
Masud, T1
San, P1
Hosking, DJ1
Chlebna-Sokół, D1
Loba-Jakubowska, E1
Sikora, A1
Lindsay, R1
Hart, DM1
Maclean, A1
Garwood, J1
Clark, AC1
Kraszewski, A1
Hulley, SB1
Vogel, JM1
Donaldson, CL1
Bayers, JH1
Friedman, RJ1
Rosen, SN1
Purnell, DC1
Jones, JD1
Becker, KL1
Lemon, HM1
Dworak, JE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Trial: Effects of Creatine Supplementation on Bone Mass and Turnover and Muscle Function in Healthy Postmenopausal Women[NCT01472393]200 participants (Anticipated)Interventional2011-11-30Recruiting
Effects of Creatine and Caffeine Co-Supplementation on Muscle Mass and Muscle Performance in Trained Young Adults[NCT04290819]36 participants (Anticipated)Interventional2019-02-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for creatine and Osteoporosis

ArticleYear
Creatine supplementation for older adults: Focus on sarcopenia, osteoporosis, frailty and Cachexia.
    Bone, 2022, Volume: 162

    Topics: Aged; Cachexia; Creatine; Dietary Supplements; Frailty; Humans; Muscle Strength; Osteoporosis; Sarco

2022
Current Evidence and Possible Future Applications of Creatine Supplementation for Older Adults.
    Nutrients, 2021, Feb-26, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Bone Density; Creatine; Dietary Supplements; Exercise; Female; Human

2021
Creatine supplementation and aging musculoskeletal health.
    Endocrine, 2014, Volume: 45, Issue:3

    Topics: Aging; Creatine; Humans; Osteoporosis; Resistance Training; Sarcopenia

2014

Trials

3 trials available for creatine and Osteoporosis

ArticleYear
Creatine Supplementation (3 g/d) and Bone Health in Older Women: A 2-Year, Randomized, Placebo-Controlled Trial.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2020, 04-17, Volume: 75, Issue:5

    Topics: Absorptiometry, Photon; Accidental Falls; Aged; Bone Density; Bone Diseases, Metabolic; Brazil; Crea

2020
Quantitative ultrasound of bone and clodronate effects in thalassemia-induced osteoporosis.
    Journal of bone and mineral metabolism, 2003, Volume: 21, Issue:6

    Topics: Adult; Amino Acids; beta-Thalassemia; Bone and Bones; Calcium; Clodronic Acid; Creatine; Humans; Inj

2003
Bone loss during oestriol therapy in postmenopausal women.
    Maturitas, 1979, Volume: 1, Issue:4

    Topics: Adult; Alkaline Phosphatase; Bone and Bones; Calcium; Clinical Trials as Topic; Creatine; Double-Bli

1979

Other Studies

13 other studies available for creatine and Osteoporosis

ArticleYear
Exercise training, creatine supplementation, and bone health in ovariectomized rats.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2015, Volume: 26, Issue:4

    Topics: Absorptiometry, Photon; Animals; Body Weight; Bone Density; Combined Modality Therapy; Creatine; Die

2015
Influence of creatine supplementation on bone quality in the ovariectomized rat model: an FT-Raman spectroscopy study.
    Lasers in medical science, 2012, Volume: 27, Issue:2

    Topics: Animals; Bone and Bones; Bone Density; Creatine; Dietary Supplements; Female; Osteoporosis; Ovariect

2012
MALABSORPTION FOLLOWING PARTIAL GASTRECTOMY.
    Journal of the Royal College of Surgeons of Edinburgh, 1963, Volume: 9

    Topics: Alkaline Phosphatase; Blood; Body Weight; Calcium Metabolism Disorders; Calcium, Dietary; Celiac Dis

1963
[REABSORPTION OF PHOSPHORUS IN THE RENAL TUBULES IN NONPARATHYROGENOUS DISEASES].
    Nordisk medicin, 1964, May-07, Volume: 71

    Topics: Adenoma; Bone Neoplasms; Breast Neoplasms; Creatine; Creatinine; Denmark; Diagnosis, Differential; H

1964
THE EFFECT OF BENDROFLUAZIDE ON URINE CALCIUM EXCRETION.
    Clinical science, 1964, Volume: 27

    Topics: Arthritis; Arthritis, Rheumatoid; Bendroflumethiazide; Calcium; Calcium Metabolism Disorders; Calciu

1964
Association of biochemical values with morbidity in the elderly: a population-based Swedish study of persons aged 82 or more years.
    Scandinavian journal of clinical and laboratory investigation, 2003, Volume: 63, Issue:7-8

    Topics: Aged; Aged, 80 and over; Biomarkers; Blood Chemical Analysis; Body Mass Index; Cholesterol; Creatine

2003
Osteoprotegerin and bone turnover markers in heavily pretreated HIV-infected patients.
    HIV medicine, 2005, Volume: 6, Issue:3

    Topics: Adult; Age Factors; Alkaline Phosphatase; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bi

2005
Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:6

    Topics: Aged; Aged, 80 and over; Body Weight; Bone and Bones; Cohort Studies; Creatine; Female; Fractures, B

2005
Vitamin D insufficiency increases bone turnover markers and enhances bone loss at the hip in patients with established vertebral osteoporosis.
    Clinical endocrinology, 1999, Volume: 51, Issue:2

    Topics: 25-Hydroxyvitamin D 2; Aged; Aged, 80 and over; Alkaline Phosphatase; Amino Acids; Bone Density; Bon

1999
Clinical evaluation of patients with idiopathic juvenile osteoporosis.
    Journal of pediatric orthopedics. Part B, 2001, Volume: 10, Issue:3

    Topics: Absorptiometry, Photon; Acute Disease; Adolescent; Alkaline Phosphatase; Body Mass Index; Bone Densi

2001
The effect of supplemental oral phosphate on the bone mineral changes during prolonged bed rest.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:12

    Topics: Administration, Oral; Adult; Alkaline Phosphatase; Body Weight; Bone and Bones; Bone Resorption; Cal

1971
Response to parathyroid hormone infusion in primary hyperparathyroidism.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:4

    Topics: Absorption; Calcium; Creatine; Graves Disease; Humans; Hypercalcemia; Hyperparathyroidism; Kidney Tu

1968
Association of human serum parathormone-like activity with pre-albumin electrophoretic zones.
    Nature, 1965, May-22, Volume: 206, Issue:4986

    Topics: Animals; Biological Assay; Blood Protein Electrophoresis; Calcium; Cattle; Chemistry Techniques, Ana

1965