geranylgeranylacetone has been researched along with Osteoporosis* in 2 studies
2 review(s) available for geranylgeranylacetone and Osteoporosis
Article | Year |
---|---|
[Effects of biologic therapies on systemic osteoporosis in patients with rheumatoid arthritis].
Biologic therapies including tumor necrosis factor alpha (TNF-alpha)-blocking therapy have been shown to reduce disease activity measures and joint damage progression. However, effects of biologic therapies on systemic osteoporosis remain to be elucidated in patients with rheumatoid arthritis (RA). In this review article, we reviewed the literature on the issue after we described our hypothesis on the pathogenesis of synovitis in patients with RA. Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Denosumab; Diterpenes; Drug Design; Humans; Infliximab; Interleukin-1; Interleukin-17; Interleukin-6; Osteoclasts; Osteoporosis; RANK Ligand; Receptors, Interleukin-6; Tumor Necrosis Factor-alpha | 2009 |
[Geranylgeranylacetone, an antiulcer drug, potently inhibits formation and function of human osteoclasts in vitro and bone loss in ovariectomized rats].
Topics: Animals; Anti-Ulcer Agents; Bone Density; Cell Differentiation; Diterpenes; Drug Design; Estrogens; Humans; Osteoclasts; Osteoporosis; Ovariectomy; Polyisoprenyl Phosphates | 2004 |