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amlodipine and Osteoporosis

amlodipine has been researched along with Osteoporosis in 5 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.

Research Excerpts

ExcerptRelevanceReference
"This study was performed to evaluate the possible protective effect of two calcium channel blocker's "lacidipine (LAC) and amlodipine (AML)" on bone metabolism in an experimental ovariectomized and inflammation-induced osteoporosis rat model (OVXinf)."7.83Effects of Administration of Amlodipine and Lacidipine on Inflammation-Induced Bone Loss in the Ovariectomized Rat. ( Albayrak, A; Ayan, AK; Aydin, A; Bayir, Y; Cadirci, E; Demirci, E; Halici, Z; Karakus, E; Ozturk-Karagoz, B; Sahin, A; Unal, D, 2016)
" In this study, we investigated whether amlodipine protects against the reduction in bone density in stroke-prone spontaneously hypertensive rats (SHR-sp)."7.76Protective effect of amlodipine against osteoporosis in stroke-prone spontaneously hypertensive rats. ( Ando, H; Fujimura, A; Ishikawa, E; Liu, Y; Maekawa, T; Motosugi, Y; Tsuruoka, S; Ushijima, K, 2010)
"This study was performed to evaluate the possible protective effect of two calcium channel blocker's "lacidipine (LAC) and amlodipine (AML)" on bone metabolism in an experimental ovariectomized and inflammation-induced osteoporosis rat model (OVXinf)."3.83Effects of Administration of Amlodipine and Lacidipine on Inflammation-Induced Bone Loss in the Ovariectomized Rat. ( Albayrak, A; Ayan, AK; Aydin, A; Bayir, Y; Cadirci, E; Demirci, E; Halici, Z; Karakus, E; Ozturk-Karagoz, B; Sahin, A; Unal, D, 2016)
"Amlodipine is capable of mitigating the negative effects of orchidectomy and could be a good prevention of osteoporosis."3.78Protective effect of amlodipine on rat bone tissue after orchidectomy. ( Gradosova, I; Hubena, S; Palicka, V; Svejkovska, K; Zivna, H; Zivny, P, 2012)
" In this study, we investigated whether amlodipine protects against the reduction in bone density in stroke-prone spontaneously hypertensive rats (SHR-sp)."3.76Protective effect of amlodipine against osteoporosis in stroke-prone spontaneously hypertensive rats. ( Ando, H; Fujimura, A; Ishikawa, E; Liu, Y; Maekawa, T; Motosugi, Y; Tsuruoka, S; Ushijima, K, 2010)
"Amlodipine treatment at doses of 1 and 3 mg/kg significantly increased the calcium (P<0."1.35Protective effects of amlodipine and lacidipine on ovariectomy-induced bone loss in rats. ( Borekci, B; Cadirci, E; Halici, Z; Ozdemir, Y; Suleyman, H, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karakus, E1
Halici, Z2
Albayrak, A1
Bayir, Y1
Demirci, E1
Aydin, A1
Ozturk-Karagoz, B1
Cadirci, E2
Ayan, AK1
Sahin, A1
Unal, D1
Ushijima, K1
Liu, Y1
Maekawa, T1
Ishikawa, E1
Motosugi, Y1
Ando, H1
Tsuruoka, S1
Fujimura, A1
Shimizu, H1
Nakagami, H1
Yasumasa, N1
Mariana, OK1
Kyutoku, M1
Koriyama, H1
Nakagami, F1
Shimamura, M1
Rakugi, H1
Morishita, R1
Gradosova, I1
Zivna, H1
Palicka, V1
Hubena, S1
Svejkovska, K1
Zivny, P1
Borekci, B1
Ozdemir, Y1
Suleyman, H1

Other Studies

5 other studies available for amlodipine and Osteoporosis

ArticleYear
Effects of Administration of Amlodipine and Lacidipine on Inflammation-Induced Bone Loss in the Ovariectomized Rat.
    Inflammation, 2016, Volume: 39, Issue:1

    Topics: Amlodipine; Animals; Bone Density; Calcium Channel Blockers; Collagen Type I; Collagen Type I, alpha

2016
Protective effect of amlodipine against osteoporosis in stroke-prone spontaneously hypertensive rats.
    European journal of pharmacology, 2010, Jun-10, Volume: 635, Issue:1-3

    Topics: Administration, Oral; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Bone Density; Ca

2010
Cilnidipine, but not amlodipine, ameliorates osteoporosis in ovariectomized hypertensive rats through inhibition of the N-type calcium channel.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:1

    Topics: Amlodipine; Animals; Antihypertensive Agents; Bone and Bones; Bone Density; Calcium Channel Blockers

2012
Protective effect of amlodipine on rat bone tissue after orchidectomy.
    Pharmacology, 2012, Volume: 89, Issue:1-2

    Topics: Alkaline Phosphatase; Amlodipine; Animals; Biomarkers; Biomechanical Phenomena; Bone and Bones; Bone

2012
Protective effects of amlodipine and lacidipine on ovariectomy-induced bone loss in rats.
    European journal of pharmacology, 2008, Jan-28, Volume: 579, Issue:1-3

    Topics: Amlodipine; Animals; Bone and Bones; Calcium; Calcium Channel Blockers; Dihydropyridines; Disease Mo

2008