2-acetylbenzothiophene has been researched along with Osteoporosis in 4 studies
*Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, HF; He, XB; Li, X; Li, ZR; Liu, ZY; Shao, HY; Si, SY; Yang, ZY; Zhang, YQ | 1 |
| Guo, HF; He, XB; Jiang, JD; Li, X; Li, ZR; Liu, ZY; Shao, HY; Si, SY; Xue, ST; Yang, ZY; Zhang, YQ | 1 |
| Guo, HF; Jin, J; Ju, DH; Li, ZR; Liu, MJ; Liu, ZY; Xue, ST | 1 |
| Guo, HF; Jin, J; Li, ZR; Liu, ZY; Xie, ZS; Xue, ST; Yi, H; Zhang, L | 1 |
4 other study(ies) available for 2-acetylbenzothiophene and Osteoporosis
| Article | Year |
|---|---|
Synthesis and evaluation of 1-(benzo[b]thiophen-2-yl)ethanone analogues as novel anti-osteoporosis agents acting on BMP-2 promotor.
Topics: Animals; Bone and Bones; Bone Morphogenetic Protein 2; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Design; Female; Gene Expression Regulation; Humans; Mice; Models, Chemical; Osteoporosis; Ovariectomy; Promoter Regions, Genetic; Rats; Thiophenes | 2009 |
Substituted benzothiophene or benzofuran derivatives as a novel class of bone morphogenetic protein-2 up-regulators: synthesis, structure-activity relationships, and preventive bone loss efficacies in senescence accelerated mice (SAMP6) and ovariectomized
Topics: Anabolic Agents; Animals; Benzofurans; Bone Density; Bone Density Conservation Agents; Bone Morphogenetic Protein 2; Cell Line; Female; Lethal Dose 50; Male; Mice; Osteoporosis; Ovariectomy; Rats; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Up-Regulation | 2010 |
Synthesis of a novel class of substituted benzothiophene or benzofuran derivatives as BMP-2 up-regulators and evaluation of the BMP-2-up-regulating effects in vitro and the effects on glucocorticoid-induced osteoporosis in rats.
Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Cell Line; Female; Glucocorticoids; Male; Mice; Mice, Inbred Strains; Osteoporosis; Rats; Rats, Wistar; Thiophenes; Up-Regulation | 2015 |
Substituted benzothiophene and benzofuran derivatives as a novel class of bone morphogenetic Protein-2 upregulators: Synthesis, anti-osteoporosis efficacies in ovariectomized rats and a zebrafish model, and ADME properties.
Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Caco-2 Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred BALB C; Molecular Structure; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiophenes; Zebrafish | 2020 |